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4篇 您的检索式:作者名="Sinnakaruppan Mathavan"
    题名 作者 年代 出处 被引量
1Transcriptomic analysis of a transgenic zebrafish hepatocellular carcinoma model reveals a prominent role of immune responses in tumour progression and regression显示文摘Zhen Li Huaien Luo Caixia Li Xiaojing Huo Chuan Yan Xiaoqian Huang Muthafar Al‐Haddawi Sinnakaruppan Mathavan Zhiyuan Gong 2014Cancer2014,,7:2
2Sperm-mediated gene transfer in the silkworm Bombyx mori archives of insect显示文摘Yusuff Shamila Sinnakaruppan Mathavan 1998Biochemistry and Physiology1998,37,:1
3Sperm-mediated gene transfer in the silkworm Bombyx mori archives of insect显示文摘 1998Biochemistry and Physiology1998,37,:1
4Oxidative stress and mitochondrial transfer:A new dimension towards ocular diseases显示文摘Ocular cells like,retinal pigment epithelium(RPE)is a highly specialized pigmented monolayer of post-mitotic cells,which is located in the posterior segment of the eye between neuro sensory retina and vascular choroid.It functions as a selective barrier and nourishes retinal visual cells.As a result of high-level oxygen consumption of retinal cells,RPE cells are vulnerable to chronic oxidative stress and an increased level of reactive oxygen species(ROS)generated from mitochondria.These oxidative stress and ROS generation in retinal cells lead to RPE degeneration.Various sources including mtDNA damage could be an important factor of oxidative stress in RPE.Gene therapy and mitochondrial transfer studies are emerging fields in ocular disease research.For retinal degenerative diseases stem cell-based transplantation methods are developed from basic research to preclinical and clinical trials.Translational research contributions of gene and cell therapy would be a new strategy to prevent,treat and cure various ocular diseases.This review focuses on the effect of oxidative stress in ocular cell degeneration and recent translational researches on retinal degenerative diseases to cure blindness.Mohana Devi Subramaniam Mahalaxmi Iyer Aswathy P.Nair Dhivya Venkatesan Sinnakaruppan Mathavan Nimmisha Eruppakotte Soumya Kizhakkillach Manoj kumar Chandran Ayan Roy Abilash Valsala Gopalakrishnan Balachandar Vellingiri 2022Genes & Diseases2022,9,3:1
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