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39篇 您的检索式:作者名="Sims I M"
    题名 作者 年代 出处 被引量
1Anti-solvent co-crystallization of carbamazepine and saccharin显示文摘Wang I C Lee M J Sim S J 2013Int J Pharm2013,450,:1
2Structural diversity of fructans from members of the order Asparagales in New Zealand显示文摘Sims I M 2003Phytochemistry2003,63,:1
3TRIP-Br:a novel family of PHD zinc finger and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1显示文摘Hsu S I Yang C M Sim K G 2001The EMBO journal2001,20,9:1
4Whole- transcriptome shotgun sequencing ( RNA-Seq ) screen reveals upregulation of cellobiose and motility operons of Lactobacillus ruminis L5 during growth on tetrasaccharides derived from barley β-glucan 显示文摘LAWLEY B SIMS I M TANNOCK G W 2013Applied and Environmental Microbiology2013,79,18:1
5Pollution of soils by the toxic spill of a pyrite mine (Aznalcollar, Spain)显示文摘M Simón I Ortiz I Garc??a E Fernández J Fernández C Dorronsoro J Aguilar 1999Science of the Total Environment1999,,1:1
6An 1HNMR Investigation into the Loci of Solubilization of 4-nitrotoluene, 2,6-dinitrotoluene, and 2,4,6-trinitrotoluene in Nonionic Surfactant Micelles 显示文摘PARK D J JAHRAUS W I SIMS J M 2011Colloids and Surfaces A : Physicochem- ical Engineering Aspects2011,3751,:1
7Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy显示文摘SIM(O) R CARRASCO E GARC(I)A-RAM(I)REZ M 2006Current Diabetes Reviews2006,2,1:1
8Human myoblast genome therapy显示文摘Human Myoblast Genome Therapy (HMGT) is a platform technology of cell transplantation, nuclear transfer, and tissue engineering. Unlike stem cells, myoblasts are differentiated, immature cells destined to become muscles. Myoblasts cultured from satellite cells of adult muscle biopsies survive, develop, and function to revitalize degenerative muscles upon transplantation. Injection injury activates regeneration of host myofibers that fuse with the engrafted myoblasts, sharing their nuclei in a common gene pool of the syncytium. Thus, through nuclear transfer and complementation, the normal human genome can be transferred into muscles of patients with genetic disorders to achieve phenotype repair or disease prevention. Myoblasts are safe and efficient gene transfer vehicles endogenous to muscles that constitute 50% of body weight. Results of over 280 HMGT procedures on Duchenne Muscular Dystrophy (DMD) subjects in the past 15 years demonstrated absolute safety. Myoblast-injected DMD muscles showed improved histology. Strength increase at 18 months post-operatively averaged 123%. In another application of HMGT on ischemic cardiomyopathy, the first human myoblast transfer into porcine myocardium revealed that it was safe and effective. Clinical trials on approximately 220 severe cardiomyopathy patients in 15 countries showed a <10% mortality. Most subjects received autologous cells implanted on the epicardial surface during coronory artery bypass graft, or injected on the endomyocardial surface percutaneously through guiding catheters. Significant increases in left ventricular ejection fraction, wall thickness, and wall motion have been reported, with reduction in perfusion defective areas, angina, and shortness of breath. As a new modality of treatment for disease in the skeletal muscle or myocardium, HMGT emerged as safe and effective. Large randomized multi-center trials are under way to confirm these preliminary results. The future of HMGT is bright and exciting.Peter K Law Danlin M Law Eugene KW Sim Khawja H Haider Margarita N Vakhromeeva Ilia I Berishvili Leo A Bockeria Choong-Chin Liew 2006Journal of Geriatric Cardiology2006,3,3:1
9Genetic mapping of a major gene affecting onion bulb fructan content 显示文摘MecallumJ Clarke A Sheffer J Shaw M Butler R Brash D Scheffer J Sims I van Heusden S Shigyo M Havey M 2006Journal of Theoretical and Applied Genetics2006,112,:1
10Changes in cell wall composition during ripening of grape berries 显示文摘Nunan K J Sims I M Bacic A 1998Plant Physiol1998,118,:1
11Physiological and morphological responses to flooding with fresh or saline water in Jatropha curcas显示文摘Gimeno V Syvertsen J P Simón I Nieves M DíazLópez L Martínez V Garcia-Sanchez F 0,,:1
12Visualization of cavitation phenomena in a Diesel engine fuel injection nozzle by neutron radiography 显示文摘Takenaka N Kadowaki T Kawabata Y Lim I C Sim C M 2005Nuclear Instruments and Methods in Physics Research Section A: Accelerators Spectrometers Detectors and Associated Equipment2005,542,13:1
13Performance enhancement of outdoor visible light communication system using selective combining receiver显示文摘I E Lee M L Sim F W L Kung 2009The Institution of Engineering and Technology Optoelectron2009,3,1:1
14Smaller right hippocampus in war veterans with posttraumatie stress disorder显示文摘Pavic L Gregurek R Rados M Brkljaci c B Brajkovic L Sim etin Pavi c I 2007Psychiatry Res2007,154,:1
15WIP Deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation显示文摘Anton I M de la Fuente M A Sims T N 2002Immunity2002,16,2:1
16The duration of acute health pro- blems in people involved with the cleanup operation of the Hebei Spir- it oil spill 显示文摘NA J U SIM M S JO I J 2012Mar Pollut Bull2012,64,6:1
17Marked en- hancement of the immune response to BioThrax (R) ( Anthrax Vaccine Adsorbed) by the TLR9 agonist CPG 7909 in healthy volunteers显示文摘RYNKIEWICZ D RATHKOPF M SIM I 2011Vaccine2011,29,37:1
18Aqueous ferric chloride doped poly for electrorheological material 显示文摘Choi H J Sim I S Jhon M S 2000Journal of Materials Science Letters2000,19,:1
19Harvesting techniques applied to microalgae:A review显示文摘Barros A I Gonalves A L Simóes M 2015Renewable and Sustainable Energy Reviews2015,41,10:1
20Highly efficient deep-blue emitting organic light emitting diode based on the multifunctional fluorescent molecule comprising covalently bonded carbazole and anthracene moieties 显示文摘KIM S H CHO I SIM M K 2011J Mater Chem2011,21,25:1
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