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4篇 您的检索式:作者名="Simone Cappello"
    题名 作者 年代 出处 被引量
1Predominant growth of Alcanivorax during experiments on “oil spill bioremediation” in mesocosms显示文摘Simone Cappello Renata Denaro Maria Genovese Laura Giuliano Michail M. Yakimov 2006Microbiological Research2006,,2:1
2Comparison the effects of bioaugmentation versus biostimulation on marine microbial community by PCR–DGGE: A mesocosm scale显示文摘In order to better understand the effects of biostimulation and bioaugmentation processes on a marine microbial community, three different mesocosm experiments were planned. Natural seawater(10.000 L) was artificially polluted with crude oil(1 L) and(1) inorganic nutrients(Biostimulating Mesocosm, BM),(2) inorganic nutrients and an inoculum of Alcanivorax borkumensis SK2(Single Bioaugmentation Mesocosm, SBM),(3) inorganic nutrients and inoculums of A. borkumensis SK2 and Thalassolituus oleivorans MIL-1(Consortium Bioaugmentation Mesocosm, CBM). During the experimental period(20 days), samples were taken from each mesocosm and the community structure was analyzed by PCR–DGGE. The 16 S r RNA gene DGGE banding patterns and sequence analysis demonstrated that biostimulation had the lowest effect on microbial biodiversity in the mesocosms; however, the biodiversity of the marine microbial community dramatically decreased in the CBM(Shannon index was 0.6 in T3). The community structures among the three mesocosms were also markedly different,and major bacteria derived from DGGE bands were related to uncultured Gamma Proteobacteria. The biodegradation results show that the Single Bioaugmentation Mesocosm(SBM) system had the highest percentage of degradation(95%) in comparison to the BM mesocosm(80%) and CBM(70%).Mehdi Hassanshahian Zeynab Bayat Simone Cappello Francesco Smedile Michail Yakimov 2016Journal of Environmental Sciences2016,28,5:1
3Crude oil-induced structural shift of coastal bacterial communities of rod bay (Terra Nova Bay, Ross Sea, Antarctica) and characterization of cultured cold-adapted hydrocarbonoclastic bacteria显示文摘Michail M. Yakimov Gabriella Gentile Vivia Bruni Simone Cappello Giuseppe D’Auria Peter N. Golyshin Laura Giuliano 2004FEMS Microbiology Ecology2004,,3:1
4Immunophenotyping identifies distinct cellular signatures for systemic lupus erythematosus and lupus nephritis显示文摘Background:Systemic lupus erythematosus(SLE)is a complex systemic autoimmune disease characterized by development of autoantibodies and multiorgan involvement.Kidney involvement,termed lupus nephritis,has major impact on life expectancy.It is increasingly recognized that SLE is likely a common clinical manifestation of pathophysiologically diverse processes,and lupus nephritis has similarly been associated with several distinct immunological processes.We compared the immune cell phenotypes of individuals with SLE in the presence or absence of nephritis.Methods:Cryopreserved peripheral blood mononuclear cells from SLE patients with and without kidney involvement underwent flow cytometric analysis to identify major populations in T cells,B cells and myeloid lineages.Results:We compared the frequencies of lymphocyte populations in 69 SLE patients without nephritis,20 SLE patients with nephritis,and 92 healthy blood donors.Patients with SLE and lupus nephritis(LN)had reduced marginal zone B cells(P<0.0001 in SLE;P=0.001 in LN),memory B cells(P=0.002 in SLE;P=0.001 in LN)and circulating T follicular helper(Tfh)memory cells(P<0.0001 in SLE and LN)compared to healthy donors.Patients with lupus nephritis had increase Th2(P<0.0001)and T regulatory cells(P<0.0001)compared to both SLE patients without nephritis and healthy donors.Conclusion:SLE patients with and without lupus nephritis have distinct immunologic differences that may reflect the unique pathophysiological processes contributing to disease manifestations.Yi Tong V.Aw Phillip J.Whiley Ayla May Lorenzo Tom Lea-Henry Somasundhari Shanmuganandam Maurice Stanley Sonia N.Babu Vicki Athanasopoulos Jean Cappello Julia I.Ellyard Matthew Cook Carola Vinuesa Giles Walters David A.Fulcher Simon H.Jiang 2023Rheumatology & Autoimmunity2023,3,1:0
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