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8篇 您的检索式:作者名="Simon Walling"
    题名 作者 年代 出处 被引量
1新生儿复苏培训降低新生儿死亡率的效能分析:文献综述,meta分析与Delphi法的应用显示文摘[背景]全球每年13600万新生儿中,约1000万需要外界的帮助才能建立自主呼吸,每年有约814000例新生儿死亡是由分娩相关足月儿死亡(以往定义为'出生窒息')所导致的。目前尚缺乏关于新生儿复苏培训降低新生儿死亡率效能的系统性评价。[目的]对在医院和社区层面开展的快速评估及初步刺激、基本的复苏措施这两种新生儿复苏培训干预方法在降低足月新生儿分娩相关死亡率('出生窒息')、早产相关并发症死亡率这两个生命指标方面的效能进行评价。[方法]采用系统综述的方法,检索并筛选符合标准的新生儿复苏培训研究文献。采用GRADE方法对文献的质量进行评价。对符合要求的文件进行Meta分析。对数据质量较低的文献采用专家咨询法估计效能大小。[结果]通过文献检索筛选了24篇新生儿复苏培训干预研究(20篇观察性研究,2篇半试验研究,2篇随机对照研究)。对其中3篇文献进行Meta分析结果显示,以医院为基础的新生儿复苏培训可使分娩相关足月儿死亡降低30%(RR=0.70,95%CI0.59~0.84);文献中涉及早产儿死亡率效能的数据质量不高,因此采用专家咨询法进行估计。以社区为基础的新生儿复苏培训干预研究具有较高的异质性,复苏培训通常是一系列培训包的一部分,且对早产儿和足月儿的定义标准不一致。专家咨询法估计结果显示,新生儿快速评估和初步刺激可使分娩相关新生儿死亡、早产儿死亡均降低10%;以医院为基础的培训可使早产儿死亡进一步降低10%,以社区为基础的培训可使分娩相关足月儿死亡率进一步降低20%,早产儿死亡率进一步降低5%。[结论]新生儿复苏培训在医院层面可以使足月新生儿分娩相关死亡率降低30%,然而中低收入水平的国家培训覆盖率仍较低。专家咨询法估计新生儿复苏培训在社区层面降低足月儿及早产儿死亡率的效能较小。需要对新生儿复苏培训的效果、成本、实施策略等进行更深入的研究与评价。Anne CC Lee Simon Cousens Stephen N Wall 徐韬 2012中国妇幼卫生杂志2012,3,2:11
2Randomized Controlled Trial of Total Immunosuppression Withdrawal in Liver Transplant Recipients: Role of Ursodeoxycholic Acid显示文摘Nimer Assy Paul C. Adams Paul Myers Verra Simon Gerry Y. Minuk William Wall Cameron N. Ghent 2007Transplantation2007,,12:2
3Endorsement advertising in aboriginal tourism: an experiment in Taiwan 显示文摘Janet Chang Geoffrey Wall Chen -Tsang (Simon) Tsai 2005International Journal of Tourism Research2005,,6:1
4Randomized Controlled Trial of Total Immunosuppression Withdrawal in Liver Transplant Recipients: Role of Ursodeoxycholic Acid显示文摘Nimer Assy Paul C. Adams Paul Myers Verra Simon Gerry Y. Minuk William Wall Cameron N. Ghent 2007Transplantation2007,,12:1
5Ammonia plasma treatment of polystyrene surfaces enhances proliferation of primary human mesenchymal stem cells and human endothelial cells显示文摘Claudia Kleinhans Jakob Barz Simone Wurster Marleen Willig Christian Oehr Michael Müller Heike Walles Thomas Hirth Petra J. Kluger 2012Biotechnology Journal2012,,3:1
6Alpha-synuclein,especially the Parkinson\'s disease-associated mutants,forms pore-like annular and tubular protofibrils 显示文摘Lashuel H A Petre B M Wall J Simon M Nowak R J Lansbury P T 2002J Mol Biol2002,322,:1
7Stoichiometry and domainal organization of the long tail-fiber of bacteriophage T4 a hinged viral adhesin 显示文摘Cerritelli ME Wall JS Simon MN 1996J Mol Biol1996,260,5:1
8Pharmacological management of neuropathic pain in patients with vestibular schwannomas:Experience of the Atlantic Lateral Skull Base Clinic显示文摘Neuropathic pain is chronic pain generated by disorders of the peripheral and central nervous system, including skull base tumours. A skull base tumour can be any type of tumour that forms in the skull base, and this includes vestibular schwannomas which arise from the sheath of the inner ear vestibulocochlear nerve(eighth cranial nerve). Growth of the tumour, surgical resection, and/or stereotactic radiotherapy may result incompression and/or irritation of the fifth cranial nerve(trigeminal nerve) resulting in facial pain and/or numbness. Non-trigeminal afferent input may contribute to the wide constellation of symptoms seen in orofacial pain patients. The purpose of this report was to develop a decision tool to guide the recognition and treatment of neuropathic pain in this specialized population. Recommendations for treatment are based on evidence presented in Canadian and international neuropathic treatment guidelines. Algorithms are included for assessment and treatment of adult patients with agents that are recognized to have analgesic efficacy within the broad context of neuropathic pain.Andrea LO Hebb Jana Sawynok Manohar Bance Simon Walling Ken Chisholm David P Morris 2014World Journal of Pharmacology2014,3,2:0
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