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| 1 | Safety and feasibility of thullium laser transurethral resection of prostate for the treatment of benign prostatic enlargement in overweight patients显示文摘Objective:We aimed to determine safety and feasibility of thulium laser transurethral vapoenucleation of prostate(ThuVEP)for treatment of obese patients affected by benign prostatic hyperplasia(BPH).Methods:We retrospectively analysed data of 452 patients with BPH who underwent ThuVEP from February 2012 to March 2016 in a single center.Patients were divided into three groups according to body mass index(BMI,kg/m^2):Normal weight(18.5≤BMI<25;Group A),overweight(25≤BMI<30;Group B)and obese(BMI≤30;Group C),for a total of 412 patients evaluable for this study.Preoperative total serum prostate-specific antigen(PSA),digital rectal examination of the prostate,transrectal ultrasound(TRUS),renal ultrasound,urine culture,uroflowmetry,International Prostate Symptoms Score(IPSS),and Quality of Life(QoL)score were analyzed.Post-operative complications,hospital stay and days of catheterization,questionnaires and uroflowmetry at 1 and 3 months after surgery were evaluated.Preoperative data,surgical outcomes,complication rate and clinical outcomes were compared between groups.Results:The median age of patients was 69 years(Interquartile Range[IQR 10]).The preoperative median IPSS among groups was 19(IQR 8.75),20(IQR 10),and 18(IQR 10)respectively.At 1 and 3 months of follow-up,this value was 8(IQR 7),8(IQR 4),7(IQR 5)and 5(IQR 6.25),5(IQR 6),6(IQR 5),respectively(all p between groups>0.05).There was no statistically significant difference among three groups as for hospital stay and days of catheterization(p>0.05).Conclusion:Our results showed that ThuVEP was safe and feasible even in overweight patients with substantially enlarged prostate. | Luca Carmignani Maria Chiara Clementi Claudia Signorini Gloria Motta Sebastiano Nazzani Franco Palmisano Elisa De Lorenzis Michele Catellani Alessandro Francesco Mistretta Andrea Conti Valeria Tringali Maria Beatrice Costa Damiano Vizziello | 2019 | Asian Journal of Urology2019，6，3： | 3 |
| 2 | Enhanced characterization of solid solitary pulmonary nodules with Bayesian analysis-based computer-aided diagnosis显示文摘The aim of this study was to prospectively assess the accuracy gain of Bayesian analysis-based computeraided diagnosis(CAD) vs human judgment alone in characterizing solitary pulmonary nodules(SPNs) at computed tomography(CT). The study included 100 randomly selected SPNs with a definitive diagnosis. Nodule features at first and follow-up CT scans as well as clinical data were evaluated individually on a 1 to 5 points risk chart by 7 radiologists, firstly blinded then aware of Bayesian Inference Malignancy Calculator(BIMC) model predictions. Raters' predictions were evaluated by means of receiver operating characteristic(ROC) curve analysis and decision analysis. Overall ROC area under the curve was 0.758 before and 0.803 after the disclosure of CAD predictions(P = 0.003). A net gain in diagnostic accuracy was found in 6 out of 7 readers. Mean risk class of benign nodules dropped from 2.48 to 2.29, while mean risk class of malignancies rose from 3.66 to 3.92. Awareness of CAD predictions also determined a significant drop on mean indeterminate SPNs(15 vs 23.86 SPNs) and raised the mean number of correct and confident diagnoses(mean 39.57 vs 25.71 SPNs). This study provides evidence supporting the integration of the Bayesian analysis-based BIMC model in SPN characterization. | Simone Perandini Gian Alberto Soardi Massimiliano Motton Raffaele Augelli Chiara Dallaserra Gino Puntel Arianna Rossi Giuseppe Sala Manuel Signorini Laura Spezia Federico Zamboni Stefania Montemezzi | 2016 | World Journal of Radiology2016，8，8： | 3 |
| 3 | Impact of complete revascularization with percutaneous coronary intervention on survival in patients with at least one chronic total occlusion显示文摘 | Valenti R Migliorini A Signorini U | 2008 | Eur Heart J2008，29，19： | 1 |
| 4 | Therapeutic hypothermia for head injury 显示文摘 | ALDERSON P GADKARY C SIGNORINI D F | 2004 | Cochrane Database Syst Rev2004，4，00： | 1 |
| 5 | Normal cerebcllar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K1 channel GIRK2显示文摘 | Liao YJ Duncan SA | 1997 | Proc Natl Acad Sci USA1997，94，： | 1 |
| 6 | Linear and nonlinear optical properties of fullerenes in solid state materials显示文摘 | Brusatin G Signorini R | 2002 | Journal of Materials Chemistry2002，12，7： | 1 |
| 7 | Exposure assessment of mycotoxins in cow’s milk in Argentina显示文摘 | Signorini M L Gaggiotti M Molineri A | 2012 | Food and Chemical Toxicology2012，50，2： | 1 |
| 8 | Oxidative stress, isoprostanes and hepatic fibrosis 显示文摘 | Comporti M Arezzini B Signorini C | 2009 | Histopathology2009，24，7： | 1 |
| 9 | Adding insult to injury: the prognostic value of early secondary insults for survival after traumatic brain injury显示文摘 | Signorini DF Andrews PJ Jones PA | 1999 | J Neurel Neuresurg Psychiatry1999，66，1： | 1 |
| 10 | Prediction of cyclosporine area under the curve using a three- point sampling strategy after NeoralTM administration显示文摘 | Gaspari F Anedda MF Signorini O | 1997 | J Am Soc Nephrol1997，8，4： | 1 |
| 11 | Feto-maternal correlation of PTX3, sFlt-1 and PlGF in physiological and pre-eclamptic pregnancies显示文摘 | Paola Algeri Sara Ornaghi Davide Paolo Bernasconi Fabrizio Cappellini Stefano Signorini Paolo Brambilla Gabriele Urban Patrizia Vergani | 2014 | Hypertension in Pregnancy2014，，3： | 1 |
| 12 | Hypoxia-induced free iron release in the red cells of newborn infants显示文摘 | Zani S Sargentini I Gioia D Signorini C Bracci R | 1998 | Acta Paediatrica1998，87，1： | 1 |
| 13 | Detecting psychiatric morbidity after st roke显示文摘 | Roncke S Machale S Signorini D | 1998 | Steroke1998，29，5： | 1 |
| 14 | A comparison of Irish set dancing and exercises for people with Parkinson's disease: a phase II feasibility study显示文摘 | Volpe D Signorini M Marchetto A | 2013 | BMC Geriatr2013，13，： | 1 |
| 15 | Determinazione del senso di sedimentazione degli strati helle formaaione arenacea dell'Appennino settentrionale 显示文摘 | Signorini R | 1936 | Bollettino Della Societa Geologica Italiana1936，55，： | 1 |
| 16 | Bone mass and quality in patients with juvenile idiopathic arthritis:longitudinal evaluation of bone mass determinants using dual energy X-ray absorptiometry,peripheral quantitative computed tomography,and quantitative ultrasonography显示文摘 | Stagi S Cavalli L Signorini C | 2014 | Arthritis Res Ther2014，，2： | 1 |
| 17 | Linear and nonlinear parameters for the analysis of fetal heart rate signal from ean-liotocgraphic recordings显示文摘 | Magenes G Cerutti | 2003 | IEEE Tram Biomed Eng2003，50，3： | 1 |
| 18 | Heart-type fatty acid-binding protein may exclude a cute myocardial infarction on admission to pain 显示文摘 | Cappellini F Da Molin S Signorini S | 2013 | Acute Card Care emergency department for chest2013，15，4： | 1 |
| 19 | Clinical evaluation of a new selfdrying silicone gel in the treatment of scars: a preliminary report 显示文摘 | Signorini M Clementoni M T | 2007 | Aesthetic Plast Surg2007，31，2： | 1 |
| 20 | Raman linewidths in ferroelectric NaNO2 显示文摘 | SIGNORINI G F BECUCCI M CASTELLUCCI E | 1994 | Chemical Physics1994，187，： | 1 |
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