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| 1 | Learning, corporate control and perfonnance requirements in venture capital contracts 显示文摘 | Chan Y Sigel D Thakor A V | 1990 | International Economic Review1990，31，： | 1 |
| 2 | Spectroscopic analysis of the structure and properties of alkali tellurite glasses显示文摘 | HEO J LAM D SIGEL G H | | 0，，02： | 1 |
| 3 | Species relationships and farina evolution in the cheilanthoid fern genus Argyrochosma (Pteridaceae) 显示文摘 | Sigel E M Windham M D Huiet L | 2011 | Syst Bot2011，36，3： | 1 |
| 4 | Experimental observation of laser-induced radiation heat waves显示文摘 | Sigel R Tsakiris G D Lavarenne F | 1990 | Phys Rev Lett1990，65，5： | 1 |
| 5 | Meat massaging: the effects of salt and phosphate and massaging on cooking loss, binding strength and exudate composition in sectioned and formed ham显示文摘 | SIGEL D G THENO D M SCHMIDIT G R | 1978 | Journal of Food Science1978，43，2： | 1 |
| 6 | Defect centers in a germanium doped silica core optical fiber显示文摘 | FRIEBELE E J GRISCOM D L SIGEL G H | 1974 | Journal of Applied Physics1974，45，8： | 1 |
| 7 | Self-calibration of a thinned, backside illuminated charge coupled devices in the soft-X-ray region显示文摘 | Li Y L Tsakiris G D Sigel R | 1995 | Sci Instrum1995，66，1： | 1 |
| 8 | Cancer statistics,2013 显示文摘 | Sigel R Naishadham D Jemal A | 2013 | CA Cancer J Clin2013，63，1： | 1 |
| 9 | Loss of kindlin-l,a human homolog of the Caenorbabditis elegans actin-extracellular-matrix linker protein UNC-112,causes Kindler syndrome显示文摘 | Sigel D Ashton G Penagos H | 2003 | Am J Hum Genet2003，73，： | 1 |
| 10 | Determination of carotid plaque risk by ultrasonic tissue characterization显示文摘 | LEE D J SIGEL B SUAMI U K | 1998 | Ultrasound Med Biol1998，24，： | 1 |
| 11 | Real-world cure rates for hepatitis C virus treatments that include simeprevir and/or sofosbuvir are comparable to clinical trial results显示文摘AIM To assess the real-world effectiveness and cost of simeprevir(SMV), and/or sofosbuvir(SOF)-based therapy for chronic hepatitis C virus(HCV) infection.METHODS The real-world performance of patients treated with SMV/SOF ± ribavirin(RBV), SOF/RBV, and SOF/RBV with pegylated-interferon(PEG) were analyzed in a consecutive series of 508 patients with chronic HCV infection treated at a single academic medical center. Patients with genotypes 1 through 4 were included. Rates of sustained virological response-the absence of a detectable serum HCV RNA 12 wk after the end of treatment [sustained virological response(SVR) 12]-were calculated on an intention-to-treat basis. Costs were calculated from the payer's perspective using Medicare/Medicaid fees and Redbook Wholesale Acquisition Costs. Patient-related factors associated with SVR12 were identified using multivariable logistic regression.RESULTS SVR 12 rates were as follows: 86%(95%CI: 80%-91%)among 178 patients on SMV/SOF ± RBV; 62%(95%CI: 55%-68%) among 234 patients on SOF/RBV; and 78%(95%CI: 68%-86%) among 96 patients on SOF/PEG/RBV. Mean costs-per-SVR 12 were $174442(standard deviation: ± $18588) for SMV/SOF ± RBV; $223003(± $77946) for SOF/RBV; and $126496(± $31052) for SOF/PEG/RBV. Among patients on SMV/SOF ± RBV, SVR12 was less likely in patients previously treated with a protease inhibitor [odds ratio(OR): 0.20, 95%CI: 0.06-0.56]. Higher bilirubin(OR: 0.47, 95%CI: 0.30-0.69) reduced the likelihood of SVR12 among patients on SOF/RBV, while FIB-4 score ≥ 3.25 reduced the likelihood of SVR 12(OR: 0.18, 95%CI: 0.05-0.59) among those on SOF/PEG/RBV. CONCLUSION SVR 12 rates for SMV and/or SOF-based regimens in a diverse real-world population are comparable to those in clinical trials. Treatment failure accounts for 27% of costs. | Kian Bichoupan Neeta Tandon James F Crismale Joshua Hartman David Del Bello Neal Patel Sweta Chekuri Alyson Harty Michel Ng Keith M Sigel Meena B Bansal Priya Grewal Charissa Y Chang Jennifer Leong Gene Y Im Lawrence U Liu Joseph A Odin Nancy Bach Scott L Friedman Thomas D Schiano Ponni V Perumalswami Douglas T Dieterich Andrea D Branch | 2017 | World Journal of Virology2017，6，4： | 1 |
| 12 | Stability of Binary Complexes of Metal Ions with Adenosine Triphosphate 显示文摘 | Backer K Mccormick D B | 1967 | Biochimica et Biophysica Acta1967，148，： | 1 |
| 13 | Self-calibration of a thinned, backside illuminated charge coupled devices in the soft X-ray region显示文摘 | Li Yuelin Tsakiris G D Sigel R | 1995 | Rev Sci Instrum1995，66，1： | 1 |
| 14 | Perraanent and transient radiation induced losses in optical fibers显示文摘 | Evans B D Jr Sigel G H | 1974 | IEEE Tram on Nuclear Science1974，21，： | 1 |
| 15 | The fiber optic dosimeter on the navigational technology satellite 2显示文摘 | Evans B D Sigel G H Jr Langworthy J B | 1978 | IEEE Tram on Nuclear Science1978，25，6： | 1 |
| 16 | Spectrascopic anlysis of the structure and properties of alkali tellurite glasses显示文摘 | HEO J LAM D SIGEL G H | 1992 | Journal of the American Ceramic Society1992，75，2： | 1 |
| 17 | Permanent and transient radiation induced losses in optical fibers 显示文摘 | Evans B D Sigel G H Jr | 1974 | IEEE Transactions on Nuclear Science1974，21，： | 1 |
| 18 | Permanent and transient radiation induced losses in optical fibers显示文摘 | EVANS B D SIGEL G H Jr | | 0，，： | 1 |
| 19 | Experimental observation of laser-induced radiation heat waves显示文摘 | Sigel R Tsakiris G D Lavarenne F | 1990 | Phys Rev Letters1990，65，5： | 1 |
| 20 | Experimental investigation of radiation heat waves driven by laser-induced Planck radiation显示文摘 | Sigel R Tsakiris G D Lavarenne F | 1992 | Phys Rev A1992，45，6： | 1 |
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