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| 1 | Predisposing factors for positive D-Xylose breath test for evaluation of small intestinal bacterial overgrowth:A retrospective study of 932 patients显示文摘AIM: To investigate, in the largest cohort to date, patient characteristics and associated risk factors for developing small intestinal bacterial overgrowth(SIBO) using the D-Xylose breath test(XBT).METHODS: We performed a retrospective crosssectional study to analyze patient characteristics who underwent the XBT for evaluation of SIBO. Diagnostic testing with the XBT was performed based on a clinical suspicion for SIBO in patients with symptoms of bloating, abdominal pain, abdominal distension, weight loss, diarrhea, and/or constipation. Consecutive electronicmedical records of 932 patients who completed the XBT at the University of Florida between 2005 and 2009 were reviewed. A two-way Analysis of Variance(ANOVA) was used to test for several associations including age, gender, and body mass index(BMI) with a +XBT. A two-way ANOVA was also performed to control for the differences and interaction with age and between genders. A similar analysis was repeated for BMI. Associations between medical conditions and prior surgical histories were conducted using the Mantel-Haenszel method for 2 by 2 contingency tables, stratified for gender. Reported odds ratio estimates reflect the odds of the prevalence of a condition within the +XBT group to that of the-XBT group. P values of less than 0.05(two-sided) were considered statistically significant.RESULTS: In the 932 consecutive eligible subjects studied, 513 had a positive XBT. A positive association was found between female gender and a positive XBT(P = 0.0025), and females with a positive test were, on average, greater than 5 years older than those with a negative test(P = 0.024). The mean BMI of positive XBT subjects was normal(24.5) and significantly lower than the subjects with a negative XBT(29.5)(P = 0.0050). A positive XBT was associated with gastroesophageal reflux disease(GERD)(OR = 1.35; 95%CI: 1.02-1.80, P = 0.04), peptic ulcer disease(PUD)(OR = 2.61; 95%CI: 1.48-4.59, P < 0.01), gastroparesis(GP)(OR = 2.04; 95%CI: 1.21-3.41, P < 0.01) and steroid use(OR = 1.35; 95%CI: 1.02-1.80, P = 0.01). Irritable bowel syndrome, independent protonpump inhibitor(PPI) usage, or previous abdominal surgery was not significantly associated with a positive XBT. No single subdivision by gender or PPI use was associated with a significant difference in the odds ratios between any of the subsets. CONCLUSION: Female gender, lower BMI, steroid use, PUD, GERD(independent of PPI use), and GP were more prevalent in patients with SIBO, determined by a positive XBT. Increasing age was associated with SIBO in females, but not in males. | Richard A Schatz Qing Zhang Nilesh Lodhia Jonathan Shuster Phillip P Toskes Baharak Moshiree | 2015 | World Journal of Gastroenterology2015,21,15: | 4 |
| 2 | Polymerization of Propylene by Mixed Ziegler-Natta and Metallocene Catalysts显示文摘 | Lisovskii A Shuster M Gishvoliner M | 1998 | Appl Organomet Chem1998,12,6: | 1 |
| 3 | Inflammatory myofibroblastie tumor of the urinary tract: a clinicopathologic study of 45 cases including a malignant example inflammatory fibrosarcoma and a subset associated with high-grade urothelial carcinoma显示文摘 | Montgomery E A Shuster D D Burkart A L | 2006 | Am J Surg Patho12006,30,12: | 1 |
| 4 | Precision and bias of target controlled propofol infusion for sedation显示文摘 | Frolich M A Dennis D M Shuster J A | 2005 | Br J Anaesth2005,94,4: | 1 |
| 5 | Genetic stability for protein expression systems in yeasts显示文摘 | Bussinear C M Shuster J A | 1994 | Dev Bio stand1994,83,: | 1 |
| 6 | Agglomeration of submicrometer particles in weak periodic shock waves显示文摘 | Shuster K Fichman M Goldshtein A | 2002 | Physics of Fluids2002,14,5: | 1 |
| 7 | RAPD marker es-timation of genetic attraction among isolated northern leopard frog popu-lation in the southwestern USA显示文摘 | Kimberling D N Ferreira A R Shuster S M | 1996 | Mol Ecol1996,5,4: | 1 |
| 8 | Modeling techniques of best management practices Rain barrels and rain gardens using EPA SWMM-5显示文摘 | Aad M P A Suidan M T Shuster W D | 2010 | Hydrol Eng2010,15,4: | 1 |
| 9 | Nitrous oxide emissions from a large, impounded river: The Ohio River显示文摘 | Beaulieu J J Shuster W D Rebholz J A | 2010 | Environmental Science and Technology2010,44,19: | 1 |
| 10 | Aurora B kinase maintains chromatin organization during the MⅠ to MⅡ transition in surf clam oocytes显示文摘 | George O Johnston M A Shuster C B | 2006 | Cell Cycle2006,5,22: | 1 |
| 11 | Nitrous oxide emissions from a large, impounded river: the Ohio River显示文摘 | Beaulieu J J Shuster W D Rebholz J A | 2010 | Environmental Science & Technology2010,44,19: | 1 |
| 12 | ^4He/^3 He thermoehronometry 显示文摘 | Shuster D L Farley K A | 2004 | Earth and Planetary Science Letters2004,217,: | 1 |
| 13 | Functional characterization of mutant androgen receptors from androgen-independent prostate cancer显示文摘 | Fenton M A Shuster T D Fertig A M | 1997 | Clin Cancer Res1997,3,8: | 1 |
| 14 | Production and in vitro characterization of recombinant chicken interleukin-2显示文摘 | STEPANIA K J A SHUSTER J E HU W | 1999 | Interferon Cytokine Res1999,19,5: | 1 |
| 15 | Quantifying the diffusion kinetics and spatial distributions of radiogenic ^4 He in minerals containing protoninduced ^3 He 显示文摘 | Shuster D L Farley K A Sisterson J M | 2004 | Earth and Planetary Science Letters2004,217,: | 1 |
| 16 | Abdominal aortic sarcoma:report of a case with long-term survival and review of the literature显示文摘 | Shuster T A Dall'Olmo C A Spadone D | 2002 | Ann Vasc Surg2002,16,: | 1 |
| 17 | A camera's view of consumer food-handling behaviors显示文摘 | ANDERSONJ B SHUSTER T A HANSEN K E | 2004 | J Am Diet Assoc2004,104,2: | 1 |
| 18 | Controls on gas transfer velocities in a large river 显示文摘 | BEAULIEU J J SHUSTER W D REBHOLZ J A | 2012 | Journal of Geophysical Research-Biogeosciences2012,117,00: | 1 |
| 19 | Performance of PVD TiN, TiCN, and TiAlN eoated cemented carbide tools in turning显示文摘 | JINDAL P C SANTHANAM A T SCHLEINKOFER U SHUSTER A F | 1999 | International Journal of Refractory Metals and Hard Materials1999,17,13: | 1 |
| 20 | The clinical impor?tance of visceral adiposity-a critical review of methods for visceral adipose tissue analysis显示文摘 | Shuster A Patlas M PinthusJH | 2012 | BrJ Radiol2012,85,1009: | 1 |