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| 1 | Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology显示文摘笨重脱氧核糖核酸的修理由小径是的核苷酸切除修理(NER ) 使内收更万用的脱氧核糖核酸之一为脱氧核糖核酸损害的移动修理小径。有 NER 小径,全球 genomic-NER (GG-NER ) 和联合抄写的 NER (TC-NER ) 的二个子集,它仅仅在包含脱氧核糖核酸损害的识别的步不同。损坏的后面的识别,亚小径然后为充满的切口 / 切除步骤和结扎步骤收敛。这评论将集中于 NER 的 GGR 亚小径,当 TCR 亚小径将在这个问题在另一篇文章被盖住时。到修理的 NER 小径的能力一个宽数组使内收部分地,茎在影响人的生理的回答和事件的一个同等地宽的数组的 NER 损坏脱氧核糖核酸和结果从涉及起始的识别的机制走。在这评论, carcinogenesis 上的 NER 的影响,神经病学的功能,到环境因素的敏感和到癌症的敏感,治疗学将被讨论。在过去的 40 年在我们 NER 小径的理解产生的知识从进展,以及从体质研究和参予这条小径的蛋白质和酶的结构的分析导致了动物模型系统,哺乳动物的遗传和试管内生物化学的领域。每研究的这些大街显著地作出贡献到我们 NER 小径怎么并且怎么工作的理解在 NER 活动的改变,积极、否定,影响人生物学。 | Sarah C Shuck Emily A Short John J Turchi | 2008 | Cell Research2008,18,1: | 7 |
| 2 | Role of functional imaging in the development and refinement of invasive neuromodulation for psychiatric disorders显示文摘Deep brain stimulation(DBS) is emerging as a pow-erful tool for the alleviation of targeted symptoms in treatment-resistant neuropsychiatric disorders. Despite the expanding use of neuropsychiatric DBS, the mecha-nisms responsible for its effects are only starting to be elucidated. Several modalities such as quantitative elec-troencephalography as well a intraoperative recordings have been utilized to attempt to understand the under-pinnings of this new treatment modality, but functional imaging appears to offer several unique advantages. Functional imaging techniques like positron emission tomography, single photon emission computed tomog-raphy and functional magnetic resonance imaging have been used to examine the effects of focal DBS on activ-ity in a distributed neural network. These investigations are critical for advancing the field of invasive neuro-modulation in a safe and effective manner, particularly in terms of defining the neuroanatomical targets and refining the stimulation protocols. The purpose of this review is to summarize the current functional neuroim-aging findings from neuropsychiatric DBS implantation for three disorders: treatment-resistant depression, obsessive-compulsive disorder, and Tourette syndrome. All of the major targets will be discussed(Nucleus ac-cumbens, anterior limb of internal capsule, subcallosal cingulate, Subthalamic nucleus, Centromedial nucleus of the thalamus-Parafasicular complex, frontal pole, and dorsolateral prefrontal cortex). We will also address some apparent inconsistencies within this literature, and suggest potential future directions for this promis-ing area. | Nolan R Williams Joseph J Taylor Kayla Lamb Colleen A Hanlon E Baron Short Mark S George | 2014 | World Journal of Radiology2014,6,10: | 6 |
| 3 | Sex differences in uric acid and risk factors for coronary artery disease显示文摘 | Katherine R Tuttle Robert A Short Richard J Johnson | 2001 | The American Journal of Cardiology2001,,12: | 2 |
| 4 | Effectiveness in the laboratory of Corexit 9527 and 9500 in dispersing fresh,weathered,and emulsion of Alaska North Slope crude oil under subarctic conditions显示文摘 | MOLES A HOLLAND L SHORT J | 2002 | Spill Science & Technology Bulletin2002,7,56: | 1 |
| 5 | The New Industrial Engineering:Information Technology and Business Process Redesign显示文摘 | DAVENPORT T H SHORT J | 1990 | Sloan Management Review1990,31,4: | 1 |
| 6 | Accumulating Sequence of Ignitions From a Propagating Pulse显示文摘 | Dold J W Short M Clarke J F | 1995 | Combustion and Flame1995,100,3: | 1 |
| 7 | Cloning and mRNA expression of the Ca2+-binding DREAM protein in the pituitary显示文摘 | Leclerc G M Leclerc G J Shorte S L | 2002 | Gen Comp Endocrinol2002,129,1: | 1 |
| 8 | Successful and fusion for thoracolumbar spine fractures : a consecutive 41/2 - year series 显示文摘 | PARKER J W short - segment LANE J R KARAIKOVIC E E | 2000 | Spine2000,25,9: | 1 |
| 9 | An application of Prony method in PSS design for multi-machine systems显示文摘 | TRUDNOWSKI D J SMITH J R SHORT T A | 1991 | IEEE Trans on Power Systems1991,6,1: | 1 |
| 10 | Polymerase chain reaction(PCR)detection of listeria monocytogenes in diluted milk and reversal of PCR inhibition caused by calcium ions显示文摘 | Bickley J Short J K McDowel D G | 1996 | Lett Appl Microbiol1996,22,2: | 1 |
| 11 | Polyphenylene sulfide coating and molding resins 显示文摘 | J N Short H W Hill Jr | 1972 | CHEMTECH1972,2,: | 1 |
| 12 | Self- rating de- pression scale in an outpatient clinic 显示文摘 | ZUNG W C RICHARDS C B SHORT M J | 1965 | Arch Gen Psychia- try1965,13,6: | 1 |
| 13 | FISH detection of PML-RARA fusion in ins (15;17) acute promyelocytic leukaemia depends on probe size显示文摘 | Campbell LJ Oei P Brookwell R ShoRt J | 2013 | Biomed Res Int2013,2013,16: | 1 |
| 14 | Urban World Herit- age Sites and the problem of authenticity显示文摘 | Pendlebury J Short M While A | 2009 | Cities2009,,6: | 1 |
| 15 | Salvage chemotherapy of relapsed or high-risk gestational trophoblastic neoplasia (GTN) with paclitaxel/cisplatin alternating with paclitaxel/etoposide (TP/TE)显示文摘 | WANG J SHORT D SEBIRE NJ | 2008 | Ann Oncol2008,5,2: | 1 |
| 16 | Using computer aided text a- nalysis to elevate constructs:An illustration using psychological cap- ital 显示文摘 | McKenny A F Short J C Payne G T | 2012 | Organizational Research Methods2012,16,1: | 1 |
| 17 | Raman Spectroscopy Detects Biochemical Changes due to Proliferation in Mammalian Cell Cultures 显示文摘 | SHORT K W CARPENTER S FREYER J P | 2005 | Biophysical Journal2005,88,6: | 1 |
| 18 | Firm,Strategic Group,and Industry Influences on Performance显示文摘 | Jeremy C Short David J Ketchen JR Timothy B Palmer G Tomas M Hult | 2007 | Strategic Management Journal2007,28,: | 1 |
| 19 | Corrosion resistance of electroplated zinc alloy coatings显示文摘 | Short N R Abibisin A Dennis J K | 1989 | Trans Inst Metal Finish1989,67,3: | 1 |
| 20 | The simultaneous determination of diazepam and its three metabolites in dog plasma by highperformance liquid chromatography with mass spectroscopy detection显示文摘 | LIU Z SHORT J ROSE A | 2001 | Journal of Pharmaceutical&Biomedical Analysis2001,26,2: | 1 |