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| 1 | Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology显示文摘笨重脱氧核糖核酸的修理由小径是的核苷酸切除修理(NER ) 使内收更万用的脱氧核糖核酸之一为脱氧核糖核酸损害的移动修理小径。有 NER 小径,全球 genomic-NER (GG-NER ) 和联合抄写的 NER (TC-NER ) 的二个子集,它仅仅在包含脱氧核糖核酸损害的识别的步不同。损坏的后面的识别,亚小径然后为充满的切口 / 切除步骤和结扎步骤收敛。这评论将集中于 NER 的 GGR 亚小径,当 TCR 亚小径将在这个问题在另一篇文章被盖住时。到修理的 NER 小径的能力一个宽数组使内收部分地,茎在影响人的生理的回答和事件的一个同等地宽的数组的 NER 损坏脱氧核糖核酸和结果从涉及起始的识别的机制走。在这评论, carcinogenesis 上的 NER 的影响,神经病学的功能,到环境因素的敏感和到癌症的敏感,治疗学将被讨论。在过去的 40 年在我们 NER 小径的理解产生的知识从进展,以及从体质研究和参予这条小径的蛋白质和酶的结构的分析导致了动物模型系统,哺乳动物的遗传和试管内生物化学的领域。每研究的这些大街显著地作出贡献到我们 NER 小径怎么并且怎么工作的理解在 NER 活动的改变,积极、否定,影响人生物学。 | Sarah C Shuck Emily A Short John J Turchi | 2008 | Cell Research2008，18，1： | 7 |
| 2 | Role of functional imaging in the development and refinement of invasive neuromodulation for psychiatric disorders显示文摘Deep brain stimulation(DBS) is emerging as a pow-erful tool for the alleviation of targeted symptoms in treatment-resistant neuropsychiatric disorders. Despite the expanding use of neuropsychiatric DBS, the mecha-nisms responsible for its effects are only starting to be elucidated. Several modalities such as quantitative elec-troencephalography as well a intraoperative recordings have been utilized to attempt to understand the under-pinnings of this new treatment modality, but functional imaging appears to offer several unique advantages. Functional imaging techniques like positron emission tomography, single photon emission computed tomog-raphy and functional magnetic resonance imaging have been used to examine the effects of focal DBS on activ-ity in a distributed neural network. These investigations are critical for advancing the field of invasive neuro-modulation in a safe and effective manner, particularly in terms of defining the neuroanatomical targets and refining the stimulation protocols. The purpose of this review is to summarize the current functional neuroim-aging findings from neuropsychiatric DBS implantation for three disorders: treatment-resistant depression, obsessive-compulsive disorder, and Tourette syndrome. All of the major targets will be discussed(Nucleus ac-cumbens, anterior limb of internal capsule, subcallosal cingulate, Subthalamic nucleus, Centromedial nucleus of the thalamus-Parafasicular complex, frontal pole, and dorsolateral prefrontal cortex). We will also address some apparent inconsistencies within this literature, and suggest potential future directions for this promis-ing area. | Nolan R Williams Joseph J Taylor Kayla Lamb Colleen A Hanlon E Baron Short Mark S George | 2014 | World Journal of Radiology2014，6，10： | 6 |
| 3 | 活性氧化铝除氟研究显示文摘针对目前活性氧化铝饮水除氟中存在的问题,进行了生产性试验研究,通过采用原水投加CO_2气体降低pH值、小颗粒活性氧化铝、大流量短历时的NaOH循环再生法等新技术,提高了活性氧化铝的吸附容量和处理水的能力,克服滤料板结和假疲劳,除氟效果稳定可靠,水质好,再生时间短,用药省,降低了基建投资和运转费用。 | North China Municipal Engineering Design Institute A full-scale plant was set up for studying the existing problems on the fluoride removal from drinking water by activated alumina. Some new methods was adopted,such as the addition of CO2to reduce water pH value,the use of small-sized activated alumina,and the employment of a cyclic regeneration at large flow rate with NaOH as regenerant,which result in the improvement of adsorption capacity of activated alumina and treatment capacity, the elimination of the hardening of filtration materials and false fatigue,stable and reliable effectiveness,good quality in water,short regeneration time,small consumption of regenerant. And then the capital and openational costs were reduced. | 1989 | 中国给水排水1989，5，3： | 5 |
| 4 | Sex differences in uric acid and risk factors for coronary artery disease显示文摘 | Katherine R Tuttle Robert A Short Richard J Johnson | 2001 | The American Journal of Cardiology2001，，12： | 2 |
| 5 | Effectiveness in the laboratory of Corexit 9527 and 9500 in dispersing fresh,weathered,and emulsion of Alaska North Slope crude oil under subarctic conditions显示文摘 | MOLES A HOLLAND L SHORT J | 2002 | Spill Science & Technology Bulletin2002，7，56： | 1 |
| 6 | 显示文摘 | Samain D Descoins C A short stereo - selective synthesis of E E - 8 10 -dode cadien - 1 - ol the sex pheromone of the codling moth Laspeyresia pomoneUa L | 1978 | Synthesis1978，，5： | 1 |
| 7 | An application of Prony method in PSS design for multi-machine systems显示文摘 | TRUDNOWSKI D J SMITH J R SHORT T A | 1991 | IEEE Trans on Power Systems1991，6，1： | 1 |
| 8 | A phase Ⅱ study using retinoids as redifferentiation agents to increase iodine uptake in metastatic thyroid cancer显示文摘 | Short SC Suovuori A Cook G | | 0，，： | 1 |
| 9 | The effect of tide range on beach morphodynamics and morphology:a conceptual beach model显示文摘 | Masselink G Short A D | | 0，，3： | 1 |
| 10 | Monitoring results of the effectiveness of surge arrester spacings on distribution line protection 显示文摘 | SHORT T A AMMON R H | 1999 | IEEE Transactions on Power Delivery1999，14，3： | 1 |
| 11 | Urban World Herit- age Sites and the problem of authenticity显示文摘 | Pendlebury J Short M While A | 2009 | Cities2009，，6： | 1 |
| 12 | Sequence analysis of marine virus communities reveals that groups of related algal viruses are widely distributed in nature 显示文摘 | SHORT S M SUTTLE C A | 2002 | Applied and Environmental Microbiology2002，68，3： | 1 |
| 13 | An in vivo Comparison of Intestinal pH and Bacteria as Physiological Trigger Mechanisms for Colonic Targeting in Man显示文摘 | Emma L McConnell a Michael D Short Abdul W Basit | 2008 | Journal of Controlled Release2008，130，： | 1 |
| 14 | Use of the polymerase chain reaction and denaturing gradient gel electrophoresis to study diversity in natural virus communites 显示文摘 | Short S M and Suttle C A | 1999 | Hydrobiologia1999，401，： | 1 |
| 15 | Measurement of interlayer spacings and crystal sizes in turbostratic carbons显示文摘 | SHORT M A WALKER P L | 1963 | Carbon1963，1，： | 1 |
| 16 | Reconstructing the keystream form a chaotic encryption scheme显示文摘 | Parker A T Short K M | 2001 | IEEE Trans Circuits Syst-I2001，48，5： | 1 |
| 17 | The induction in vitro of adventitious shoots in Rosa显示文摘 | LLOYD D ROBERTS A V SHORT K C | 1988 | Euphytica1988，37，： | 1 |
| 18 | Using computer aided text a- nalysis to elevate constructs:An illustration using psychological cap- ital 显示文摘 | McKenny A F Short J C Payne G T | 2012 | Organizational Research Methods2012，16，1： | 1 |
| 19 | On the use of Earth radiation budget statistics for studies of clouds and climate显示文摘 | Dennis L Hartmann and David A Short | 1980 | Journal of the Atmospheric Sciences1980，37，： | 1 |
| 20 | TRMM radar observations of shallow precipitation over the tropical oceans 显示文摘 | Short D A Nakamura K | 2000 | J Climate2000，13，23： | 1 |
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