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| 1 | ADP-ribosylation factor proteins mediate agonist-induced activation of phospholipase D显示文摘 | Shome K Nie Y Romero G | 1998 | J Biol Chem1998，273，30： | 1 |
| 2 | Treatment of Kounis syndrome显示文摘 | Cevik C Nugent K Shome G P | 2010 | Int J Cardiol2010，143，： | 1 |
| 3 | The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade显示文摘 | Andresen BT Rizzo MA Shome K | 2002 | FEBS Lett2002，53，： | 1 |
| 4 | The role of phosphatidic acid in the regulation of the ras/MEK/Erk signaling cascade 显示文摘 | ANDRESEN B T RIZZO M A SHOME K | 2002 | FEBS Lett2002，531，1： | 1 |
| 5 | The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade显示文摘 | Andresen BT Rizzo MA Shome K | 2002 | FEBS Lett2002，531，1： | 1 |
| 6 | Earthquakes, records, and nonlinear responses 显示文摘 | Shome N Cornell C A Bazzurro P | 1998 | Earthquake Spectra1998，14，3： | 1 |
| 7 | Fungal keratitis with the type 1 Boston keratoprosthesis: early Indian experience 显示文摘 | Jain V Mhatre K Shome D Pineda R | 2012 | Cornea2012，31，7： | 1 |
| 8 | Continuous cooling transformation diagrams applicable to the heat affected zone of HSLA-80 and HSLA 100 steels显示文摘 | Shome M Mohanty O N | 2006 | Metallurgical and Materials Transac tions2006，37，7： | 1 |
| 9 | AT2 receptors cross talk with AT1 receptors through a nitric oxide - and RhoA - dependent mechanism resulting in decreased phospholipase D activity显示文摘 | Andresen BT Shome K | 2005 | Am J Physid Renal Physiol2005，288，： | 1 |
| 10 | Surgically induced necrotiz- ing seleritis after pterygium surgery with eonjunctival autograft显示文摘 | Jain V Shome D Natarajan S | 2008 | Cornea2008，27，： | 1 |
| 11 | A Modified Analytical Approach for Modeling Grain Growth in the Coarse Grain HAZ of HSLA Steels显示文摘 | SHOME M GUPTA O P MOHANTY O N | 2004 | Seripta Mater2004，，50： | 1 |
| 12 | Haemostatic changes in children with cyanotic and acyanotic congenital heart disease显示文摘 | Goel M Shome DK Singh ZN | 2000 | Indian Heart J2000，52，5： | 1 |
| 13 | Continuous cooling transformation diagrams applicable to the heat-affected zone of HSLA-80 and HSLA- 100 steels显示文摘 | Shome M Mohanty O N | 2004 | Metallurgical and Materials Transactions2004，37，7： | 1 |
| 14 | Effect of simulated thermalcycles on the microstructure of the heat-affected zone in HSLA-80and HSLA-100 steel plates 显示文摘 | Shome M Gupta 0 P Mohan ty 0 N | 2004 | Metallurgical and MaterialsTransactions A2004，35，3： | 1 |
| 15 | In situ synthesized Ag nanoparticle in self-assemblies of amino acid based amphiphilic hydrogelators:development of antibacterial soft nanocomposites显示文摘 | Shome A Dutta S Maiti S | | 0，，： | 1 |
| 16 | Serological profiling of Crohn’s disease and ulcerative colitis patients reveals anti-microbial antibody signatures显示文摘BACKGROUND The healthcare burden of inflammatory bowel disease(IBD)is rising globally and there are limited non-invasive biomarkers for accurate and early diagnosis.AIM To understand the important role that intestinal microbiota play in IBD pathogenesis and identify anti-microbial antibody signatures that benefit clinical management of IBD patients.METHODS We performed serological profiling of 100 Crohn’s disease(CD)patients,100 ulcerative colitis(UC)patients and 100 healthy controls against 1173 bacterial and 397 viral proteins from 50 bacteria and 33 viruses on protein microarrays.The study subjects were randomly divided into discovery(n=150)and validation(n=150)sets.Statistical analysis was performed using R packages.RESULTS Anti-bacterial antibody responses showed greater differential prevalence among the three subject groups than anti-viral antibody responses.We identified novel antibodies against the antigens of Bacteroidetes vulgatus(BVU_0562)and Streptococcus pneumoniae(SP_1992)showing higher prevalence in CD patients relative to healthy controls.We also identified antibodies against the antigen of Streptococcus pyogenes(SPy_2009)showing higher prevalence in healthy controls relative to UC patients.Using these novel antibodies,we built biomarker panels with area under the curve(AUC)of 0.81,0.87,and 0.82 distinguishing CD vs control,UC vs control,and CD vs UC,respectively.Subgroup analysis revealed that penetrating CD behavior,colonic CD location,CD patients with a history of surgery,and extensive UC exhibited highest antibody prevalence among all patients.We demonstrated that autoantibodies and anti-microbial antibodies in CD patients had minimal correlation.CONCLUSION We have identified antibody signatures for CD and UC using a comprehensive analysis of antimicrobial antibody response in IBD.These antibodies and the source microorganisms of their target antigens improve our understanding of the role of specific microorganisms in IBD pathogenesis and,after future validation,should aid early and accurate diagnosis of IBD. | Mahasish Shome Lusheng Song Stacy Williams Yunro Chung Vel Murugan Jin G Park William Faubion Shabana F Pasha Jonathan A Leighton Joshua LaBaer Ji Qiu | 2022 | World Journal of Gastroenterology2022，28，30： | 1 |
| 17 | Head group modulated pH-responsive hydrogel of amino acid-based amphiphiles: entrapment and release of cytochrome c and vitamin B12 显示文摘 | Shome A Debnath S Das PK | 2008 | Langmuir2008，24，8： | 1 |
| 18 | Effect of simulated thermal cycles on the microstructure of the heat-affected zone in HSLA-80 and HSLA-10 steelplates显示文摘 | Shome M Gupta O P Mohanty O N | 2004 | Metallurgical and Materials Transactions A2004，35，3： | 1 |
| 19 | Effect of simulated thermal cycles on the microstructure of the heat-affected zone in HSLA-80 and HSLA-100 steel plates显示文摘 | M. Shome O. P. Gupta O. N. Mohanty | 2004 | Metallurgical and Materials Transactions A2004，，13： | 1 |
| 20 | The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade显示文摘 | ANDRESSN BT RIZZO MA SHOME K | 2002 | FEBS Lett2002，531，1： | 1 |
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