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| 1 | Antihyperglycemic and antioxidant effects of Solanum xanthocarpum leaves(field grown & in vitro raised) extracts on alloxan induced diabetic rats显示文摘Objective:To investigate antidiabetic efficacy of the extract of field grown and in vitro raised leaves of Solanum xanthocarpum(S.xanthocarpum) against alloxan induced diabetic rats. Methods:The antidiabetic activity of the crude methanol extracts of the field grown and in vitro raised leaves of S.xanthocarpum at different concentrations(100-200 mg/kg bw) was tested against alloxan induced diabetic rats.The antidiabetic efficacy was validated through various biochemical parameters and the antioxidant effect was also determined.The phytochemical analyses of field grown S.xanthocarpum and in vitro rasied 5.xanthocarpum leaves were done by estimating their chlorophyll,carotenoids,total sugar,protein,amino acid and minerals contents. Results:The results revealed that the methanol extracts of both the leaves(field grown and in vitro raised) of S.xanthocarpum was efficient anti hyperglycemic agents at a concentration of 200 mg/kg bw and posses potent antioxidant activity.However,the extracts of in vitro rasied S.xanthocarpum raised leaves exhibit higher efficacy than the field grown leaves in all tested concentrations.Proximal composition and mineral analysis of S.xanthocarpum revealed higher concentration of contents in in vitro rasied S.xanthocarpum than field grown S.xanthocarpum. Conclusions:From the results it can be concluded that the leaves extracts of S.xanthocarpum can be a potential candidate in treating the hyperglycemic conditions and suits to be an agent to reduce oxidative stress. | K Poongothai P Ponmurugan K Syed Zameer Ahmed B Senthil Kumar SA Sheriff | 2011 | Asian Pacific Journal of Tropical Medicine2011,4,10: | 9 |
| 2 | Lycopene stabilizes lipoprotein levels during D-galactosamine/lipopolysaccharide induced hepatitis in experimental rats显示文摘Objective:To investigate the effect of lycopene on lipoprotein metabolism during D-galactosamine/lipopolysacchoride(D-Gal/LPS)induced hepatitis in experimentul rats.Methods:The efficacy of lycopene was validated during D-Gal/LPS induced hepatitis by analyzing the activity of lipid metabolizing enzymes such as lipoprotein lipase(LPL),lecithincholesterol acyl transferase(LCAT)and hepatic triglyceride lipase(HTCL).Lipo protein analyses were done by the estimation of very low density lipoprotein cholesterol(VLDL),low density lipoprotein cholesterol(LDL)and high density lipoprotein cholesterol(HDL).Remits:The toxic insult of D-galactosamine/lipopolysaccharide(D-Gal/LPS)in experimental group of animals reduces the normal values of lipid metabolizing enzymes due to liver injury.The significant drop in the levels of HDL and concomitant increase in the values of VLDL and LDL were observed.The pretreatment of lycopene restore these altered values to near normal level in experimental group of animals.Conclusions:In the light of results,it can be concluded that administration lycopene stabilizes the lipoprotein levels by regulating the lipid metabolizing enzymes through its antioxidant defense and helps to maintain the normal lipid metabolism during toxic injury in liver. | Sheik Abdulazeez Sheriff Thiruvengadam Devaki | 2012 | Asian Pacific Journal of Tropical Biomedicine2012,2,12: | 4 |
| 3 | 复合铸造制备稻壳灰增强AA6061铝合金及表征(英文)显示文摘稻壳灰(RHA)是一种有潜力的廉价铝基复合材料的增强颗粒。采用复合铸造方法制备不同稻壳灰含量(0,2%,4%,8%,质量分数)增强的AA6061铝合金复合材料。采用X射线衍射和扫描电镜对所制备复合材料进行表征。X射线衍射谱表明AA6061/RHA铝基复合材料中除RHA颗粒外未形成其他金属间化合物。扫描电镜图片表明RHA颗粒均匀分布在铝基体中。RHA基本分布在晶粒内部。此外,RHA颗粒与铝基体结合良好并形成清晰的界面。RHA颗粒的添加能提高铝基复合材料的显微硬度和抗拉强度。铝基复合材料的拉伸行为与其微观组织密切相关。 | J.ALLWYN KINGSLY GLADSTON N.MOHAMED SHERIFF I.DINAHARAN J.DAVID RAJA SELVAM | 2015 | Transactions of Nonferrous Metals Society of China2015,25,3: | 2 |
| 4 | hemodynamic conse-quences of rapid changes in posture in humans显示文摘 | Sheriff DD Ndland IH Toska K | 2007 | J ApplPhysiol2007,103,8: | 1 |
| 5 | Epidermal transpiration and stomata responses to humidity: some hypotheses explored显示文摘 | Sheriff D W | 1984 | Plant Cell Environment1984,,7: | 1 |
| 6 | Complex seismic trace analysis显示文摘 | Taner M T Koehler F Sheriff R E | 1979 | Geophysics1979,44,6: | 1 |
| 7 | Measuring stress in wildlife:Techniques for quantifying glucocorticoids显示文摘 | Sheriff M J Dantzer B Delehanty B Plame R Boonstra R | 2011 | Oecologia2011,166,: | 1 |
| 8 | Role of sympathetic re-sponses on the hemodynamic consequences of rapid changes inposture in humans显示文摘 | Sheriff DD Ndland IH Toska K | 2010 | J Appl Physiol2010,108,7: | 1 |
| 9 | Complex seismic trace analysis显示文摘 | Taner M T Koehler F Sheriff R E | 1979 | Geophysics1979,44,6: | 1 |
| 10 | A non-invasive technique for analyzing fecal cortisol metabolites in snowshoe hares(Lepus americanus)显示文摘 | Sheriff M J Bosson C O Krebs C J Boonstra R | 2009 | Journal of Comparative Physoiology2009,179,: | 1 |
| 11 | Complex seismic Trace analysis显示文摘 | Taner M T Koehler F Sheriff R E | 1979 | Geophysics1979,44,6: | 1 |
| 12 | The collectins in innate immunity 显示文摘 | Epstein J Eichbaum Q Sheriff S | 1996 | Current Opinion in Immunology1996,8,1: | 1 |
| 13 | Prospect development in a sequence stratigraphic framework using high resolution seismic data显示文摘 | CHOWDHURY A SHERIFF R E | 1996 | The Leading Edge1996,,3: | 1 |
| 14 | Limitations on resolution of seismic reflec-tion and geologic detail derivable from them显示文摘 | Sheriff R E | 1977 | AAPGMem1977,26,: | 1 |
| 15 | Ghrelin receptor agonist,GHRP-2,attenuates burn injury-induced MuRF-1and MAFbx expression and muscle proteolysis in rats显示文摘 | Sheriff S Joshi R Friend LA | | 0,,: | 1 |
| 16 | Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery显示文摘 | Cheng J Teply BA Sheriff I | | 0,,: | 1 |
| 17 | Complex seismic trace analysis 显示文摘 | Taner M T Koehler F Sheriff R E | 1979 | Geophysics1979,44,6: | 1 |
| 18 | The diabetes epidemic in Sri Lanka-a growing problem显示文摘 | Katulanda P Sheriff MH Matthews DR | 2006 | Ceylon Med J2006,51,1: | 1 |
| 19 | Diagnostic procedures facilitate the solving of gas flow problems显示文摘 | Sheriff D | 1995 | Solid State Technology1995,8,: | 1 |
| 20 | Metabolic profil- ing comparison of human pancreatic ductal epithelial cells and three pancreatic cancer cell lines using nmr based metabonomics显示文摘 | Watanabe M Sheriff S Lewis KB | 2012 | Journal of molecular biomarkers & diagnosis''2012,3,2: | 1 |