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| 1 | Hepatopancreatoduodenectomy for metastatic duodenal gastrointestinal stromal tumor显示文摘BACKGROUND: Duodenal gastrointestinal stromal tumors, which are rare, comprise 3%-5% of all gastrointestinal stromai tumors. We present a case of a metastatic duodenal gastrointestinal stromal tumor that was successfully treated by simultaneous tight hemihepatectomy and pancreaticoduodenectomy. METHODS: A 50-year-old woman was admitted to our department for the treatment of a possible metastatic duodenal gastrointestinal stromal tumor (GIST). At laparotomy a large duodenal tumor was found displacing the head of the pancreas. A 3 cm in diameter lesion in the posterior aspect of segment Ⅷ of the liver was also noted. Simultaneous right hepatectomy and pancreaticoduodenectomy were performed. RESULTS: Histological examination revealed a high grade metastatic duodenal GIST strongly positive for c-kit, CD34, and vimentin. The patient had no additional therapy. A follow-up of 21 months showed that the patient is very well and there is no evidence of recurrent diseases. CONCLUSIONS: Malignant stromai tumors of the duodenum are rarely encountered. They are usually slow growing, and may be amenable to curative surgery, even after occurrence of metastases. Resection of localized liver metastasis is still advocated when feasible, since imatinib does not provide a complete or long-term response. Combined surgical resection is an efficacious treatment for patients with metastatic duodenal gastrointestinal stromal tumor. | Charalabos Stratopoulos Zahir Soonawalla Juan Piris Peter J Friend | 2006 | Hepatobiliary & Pancreatic Diseases International2006，5，1： | 3 |
| 2 | Electroluminescence in conjugated polymers 显示文摘 | FRIEND R H GYMER R W HOLMES A B | 1999 | Nature1999，397，： | 2 |
| 3 | New oral delivery systems for treatment of inflammatory bowel disease显示文摘 | David R. Friend | 2004 | Advanced Drug Delivery Reviews2004，，2： | 2 |
| 4 | Why European Universities and Funding Agencies are Committing to Open Access显示文摘New opportunities presented by technological developments are being realised but more can be achieved in opening access to scientific reports and data. Funding agencies and universities are beginning to realise the benefits from an open access model for the dissemination of research results. European funding agencies and universities are following two strategies towards open access, the deposit of research reports in repositories and the conversion of journals to an open access business model. Various public statements have been made in support of open access, and several organizations-such as JISC in the UK-are undertaking work to assist all stakeholders in scholarly communication in introducing beneficial changes. | Frederick J Friend | 2006 | 图书情报工作2006，50，1： | 2 |
| 5 | Colon-specific drug delivery显示文摘 | Friend D R | 1981 | Adv Drug Deliv Rev1981，7，： | 1 |
| 6 | Variations in tight junctions and gap junctions in mammalian tissues显示文摘 | Gilula NB | 1972 | J Cell Biol1972，53，3： | 1 |
| 7 | The effect of particulate oxidation on the age-hardening characteristics of SiC/6061 MMC produced by the preforming infiltration route显示文摘 | FRIEND C M | 1992 | Seripta Metall1992，26，3： | 1 |
| 8 | A modification to improve technical success rate of small bowel transplantation in rats 显示文摘 | Soin AS Friend PJ | 1996 | Transplant Proc1996，28，5： | 1 |
| 9 | Interleukin-3,GMCSF and G-CSF receptor expression on cell lines and primary leukemia cells:receptor heterogeneity and relationship to growth factor responsiveness显示文摘 | Park L S Waldron P E Friend D | 1989 | Blood1989，74，： | 1 |
| 10 | Improved operational stability of polyfluorene-based organic light-emitting diodes with plasma-treated indium-tin-oxide anodes显示文摘 | KIM J S FRIEND R H CACIALLI F | 1999 | Appl Phys Lett1999，74，21： | 1 |
| 11 | Fabrication of microfluidic devices using polydimethylsiloxane显示文摘 | Friend J Yeo L | 2010 | Biomicrofluidics2010，4，2： | 1 |
| 12 | Procalcitonin elevation suggests a septic source显示文摘 | Friend KE Burgess JN Britt RC | 2014 | AmSurg2014，80，9： | 1 |
| 13 | High-yield preparation of isolated rat liver parenchymal cells:a biochemical and fine structural study显示文摘 | Berry MN Friend DS | 1969 | J Cell Biol1969，43，3： | 1 |
| 14 | Effect of crystal nature on upconversion luminescence in Er3:ZrO2nanocrystals显示文摘 | PATRAC A CHRISTOPHER S FRIEND R K | 2003 | Appl Phys Lett2003，，83： | 1 |
| 15 | Miniature inhalation therapy platform using surface acoustic wave microfluidic atomization显示文摘 | Qi A Friend JR Yeo LY | 2009 | Lab Chip2009，9，15： | 1 |
| 16 | JT-60SU divertor conceptual design显示文摘 | Friend M E Baxi C B Ihida S | 2001 | Fusion Technology2001，39，2： | 1 |
| 17 | Increased severity of local and systemic anaphylactic reactions in gp49B1-deficient mice显示文摘 | Daheshia M Friend D S Grusby M J | 2001 | J Exp Med2001，194，2： | 1 |
| 18 | Platelet responsiveness to aspirin in patients with hyperlipidaemia显示文摘 | Friend M Vucenik I Miller M | 2003 | BMJ2003，326，7380： | 1 |
| 19 | Comparison of four methods of calf confinement physiology显示文摘 | Friend T H Dellemier E E | 1985 | Anita Sci1985，60，： | 1 |
| 20 | Evolutionary and ecophysiological re- sponses of mountain plants to the growing season environment显示文摘 | Friend A D Woodward F I | 1990 | Advances in Ecological Research1990，20，： | 1 |
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