|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Expression of TRAIL Receptors in Human Hepatocellular Carcinoma and Apoptosis Induced by TRAIL显示文摘Objective: To investigate the expression of TRAIL receptors in human hepatocellular carcinoma and neighboring non-tumor liver tissues and to study its roles in apoptosis of SK-Hepl cell line. Methods:The expression of TRAIL receptors in hepatocellular carcinoma and in SK-Hepl cell line was detected by immunohistochemical staining and RT-PCR, and the apoptosis of SK-Hepl cell line induced by recombi-nant human TRAIL together with or without INF-γ was measured by FCM. Results: The expression of four TRAIL receptors was detectable in human hepatocellular carcinoma and neighboring non-tumor liver tissues. High expression of DR4 and DR5 was detected in tumor and neighboring non-tumor liver tissues whereas low expression of DcR1 and DcR2 was found in tumor, significantly lower than that in normalliver tissues (67.86% vs 100%, 78.57% vs 100%, respectively, P<0.01. TRAIL together with INF-γ stronglyincreased the apoptosis of SK Hepl cell line. Conclusion: The four TRAIL receptors can be detected in hepatocellular carcinoma and in SK-Hepl cell line. Combinations of TRAIL and INF-γ may be a useful alternative to HCC. | GERuiliang SHENFeng WUMengchao | 2003 | The Chinese-German Journal of Clinical Oncology2003，2，3： | 4 |
| 2 | BEACON SYNCHRONIZATION TECHNOLOGY FOR “BEIDOU” TERRESTRIAL IMPROVEMENT SYSTEM显示文摘Synchronization is an essential technology in the radio navigation system. The technique for improving the “Beidou” positioning ability is presented through constituting the terrestrial improvement system, and the beacon synchronization of the improvement system with the “Beidou” one-way time transfer model is realized.The direct digital synthesis (DDS) is adopted to generate the pseudo-random code clock having high precision and stability. Meanwhile, the CPLD device is used to design the synchronization pulse picking-up module, the spread spectrum PN code generator and the spread spectrum modulator. Measurement results indicate that the beacon synchronization has the high precision and the stability. | WEIJin-chen TANGJi-qiang SHENFeng | 2005 | Transactions of Nanjing University of Aeronautics and Astronautics2005，22，2： | 2 |
| 3 | In Vitro and in Vivo Study of the Antitumor Effects of a THANK Modified Hepatoma Cell Line显示文摘Objective THANK, known as a member of TNF superfamily,is a petent costimulator of both B and T lymphocytes and can promote a strong immune response.To investigate its role in liver immunotherapy,the anti-tumor effects of the THAND-transduced hepatoma cell line SMMU-7721 in vitro and in vivo studied. Methods THANK full-elngth cDNA was transfected into SMMU-7721 cell line .The transfectant with stable expression of THAND was obtained by clone selection and THANK's effects on hepatoma cells were analyzed,further the tumorigenicity of THANK -transduced 7721 cells was examined in nude mice.Results THANK's expression in 7721 cells inhibited the growth of hepatoma cells and induced a strong CTL response in vitro.The cell cycle analysis showed that THANK transfected 7721 cells were arrested in the S phase.The expression of THANK in SMMU-7721 cell line not only inhibited the tumorigenicity of 7721 cells,but also induced a systemic immune response against re-chalenge of parental 7721 tumors. Conclusion THANK transduction in SMMU-7721 cells can induce an effective immune response in nude mice and may be useful for the immunotherapy of hepatomas. | WUDong SHENFeng 等 | 2002 | The Chinese-German Journal of Clinical Oncology2002，1，2： | 2 |
| 4 | Film mor- phology and orientation of amino silicone adsorbed onto cellu- lose substrate 显示文摘 | XU Yingjun YIN Hong YUAN Shenfeng | 2009 | Applied Surface Science2009，255，： | 1 |
| 5 | Study on the Separation of Binary Azeotropic Mixtures by Continuous Extractive Distillation显示文摘 | Yuan Shenfeng Zou Cancan Yin Hong | 2015 | Chem Eng Res Des2015，93，： | 1 |
| 6 | Modulation of Synaptic Plasticity and Memory by Reelin Involves Differential Splicing of the Lipoprotein Receptor Apoer2显示文摘 | Uwe Beffert Edwin J. Weeber Andre Durudas Shenfeng Qiu Irene Masiulis J. David Sweatt Wei-Ping Li Giselind Adelmann Michael Frotscher Robert E. Hammer Joachim Herz | 2005 | Neuron2005，，4： | 1 |
| 7 | Kinetics of water–isocyanate reaction in N,N-dimethylformamide显示文摘The uncatalyzed reaction of p-tolyl isocyanate(p-TI)with water in N,N-dimethylformamide(DMF)was investigated by high performance liquid chromatography(HPLC).The reactions were carried out at different temperatures from 293 K to 323 K,using various molar ratios of water to p-TI.DMF,as a special amide,was proved to be an efficient catalyst for water–isocyanate reaction.Under the reaction conditions in this study,substituted urea was the only final product observed.An appreciable amount of intermediate p-toluidine was detected.Concentrations of the isocyanate group as well as the amine and urea were determined as a function of time.New kinetic equations were deduced for each of the substance on the basis of a multistep mechanism,instead of a simple second order reaction as usual.Kinetic constants were calculated using the software MATLAB.Furthermore,the effects of temperature and concentrations of reactants on the reaction rate and amine content were discussed.The activation energy of each step was also determined. | Zhirong Chen Weitao Yang Hong Yin Shenfeng Yuan | 2017 | Chinese Journal of Chemical Engineering2017，25，10： | 1 |
| 8 | Yield, grain quality and water use efficiency of rice under non-flooded mulching cultivation显示文摘 | Zichang Zhang Shenfeng Zhang Jianchnag Yang Jianhua Zhang | 2008 | Field Crops Research2008，，1： | 1 |
| 9 | Separation of acetone-tetrahydrofuran azeotropic mixture by continous extractive distillation显示文摘 | Yuan Shenfeng Yang Wendong Yin Hong | 2013 | J Chem Technol Biotechnol2013，88，： | 1 |
| 10 | A rhodamine-based chromogenic and fluorescent chemosensor for copper ion in aqueous media显示文摘 | Minglei Zhao Xiao-Feng Yang Shenfeng He Liping Wang | 2008 | Sensors & Actuators: B Chemical2008，，2： | 1 |
| 11 | Layered Structure and Management in Intemet of Ttings显示文摘 | Huansheng Ning Na Ning Shenfeng Oil | 2007 | Future generation conmmnication and networklng(fgcn 2007)2007，2，68： | 1 |
| 12 | Enhanced oral bioavailability of paclitaxel formulated in vitamin E‐TPGS emulsified nanoparticles of biodegradable polymers: In vitro and in vivo studies显示文摘 | LingyunZhao Si‐ShenFeng | 2010 | J Pharm Sci2010，，8： | 1 |
| 13 | Film morphology and orientation of amino silicone adsorbed onto cellulose substrate 显示文摘 | XU YINGJUN YIN HONG YUAN SHENFENG | 2009 | Applied Surface Science2009，255，： | 1 |
| 14 | Film morphology and orientation of amino silicone adsorbed onto cellulose substrate 显示文摘 | Xu Yingjun Yin Hong Yuan Shenfeng | 2009 | Applied Surface Sci2009，255，20： | 1 |
| 15 | Film morphology and oriention of amino silicone adsorbed onto cellulose substrate显示文摘 | XU Yingjun YIN Hong YUAN Shenfeng | 2009 | Applied Surface Science2009，255，： | 1 |
| 16 | Film morphology and orientation of amino silicone adsorbed onto cellulose substrate 显示文摘 | XU Yingjun YIN Hong YUAN Shenfeng | 2009 | Applied Surface Science2009，255，： | 1 |
| 17 | Induced Neural Stem Cells Generated from Rat Fibroblasts显示文摘The generation of induced tissue-specifc stem cells has been hampered by the lack of well-established methods for the maintenance of pure tissue-specifc stem cells like the ones we have for embryonic stem(ES)cell cultures.Using a cocktail of cytokines and small molecules,we demonstrate that primitive neural stem(NS)cells derived from mouse ES cells and rat embryos can be maintained.Furthermore,using the same set of cytokines and small molecules,we show that induced NS(iNS)cells can be generated from rat fbroblasts by forced expression of the transcriptional factors Oct4,Sox2 and c-Myc.The generation and long-term maintenance of iNS cells could have wide and momentous implications. | Guangjun Xi Pingfang Hu Cunye Qu Shenfeng Qiu Chang Tong Qi-Long Ying | 2013 | Genomics, Proteomics & Bioinformatics2013，11，5： | 1 |
| 18 | Film morphology and oriention of amino silicone adsorbed onto cellulose substrate显示文摘 | XU Yingjun YIN Hong YUAN Shenfeng | 2009 | Applied Surface Science2009，，255： | 1 |
| 19 | Array pattern synthesis with robustness against manifold vector uncertainty显示文摘 | SHENFENG YAN JEN M HOVEM | 2008 | IEEE Journal Of Oceanic Engineering2008，33，4： | 1 |
| 20 | Study on the separation of binary azeotropic mixtures by continuous extractive distillation显示文摘 | Yuan Shenfeng Zou Cancan Yin Hong | 2015 | Chemical Engineering Research and Design2015，93，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员