5篇
您的检索式：作者名="Sheela Devi"
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| 1 | Longer period of oral administration of aspartame on cytokine response in Wistar albino rats显示文摘 | Choudhary AK Sheela Devi R | 2015 | Endocrinol Nutr2015，62，3： | 1 |
| 2 | A study on antibiotic susceptibility and resistance profiles of bacterial strains isolated from patients with urinary tract infection(uti)at kanchipuram district,tamil- nadu,india显示文摘 | Sheela Devi A Rajkumar J | 2013 | International Journal of Pharmacy & Pharmaceuti- cal Sciences2013，193，3： | 1 |
| 3 | Effects of aspartame on hsp70,bcl-2 and bax expression in immune organs of Wistar albino rats显示文摘Aspartame,a 'first generation sweetener',is widely used in a variety of foods,beverages,and medicine.The FDA has determined the acceptable daily intake(ADI) value of aspartame to be 50 mg/kg-day,while the JECFA(Joint FAO/WHO Expert Committee on Food Additives) has set this value at 40 mg/kg of body weight/day.Safety issues have been raised about aspartame due to its metabolites,specifically toxicity from methanol and/or its systemic metabolites formaldehyde and formic acid.The immune system is now recognized as a target organ for many xenobiotics,such as drugs and chemicals,which are able to trigger unwanted apoptosis or to alter the regulation of apoptosis.Our previous studies has shown that oral administration of aspartame[40 mg/(kg.day)]or its metabolites for 90 days increased oxidative stress in immune organs of Wistar albino rats.In this present study,we aimed to clarify whether aspartame consumption over a longer period(90-days) has any effect on the expression of hsp70,bcl-2 and bax at both mRNA transcript and protein expression levels in immune organs.We observed that oral administration of aspartame for 90 days did not cause any apparent DNA fragmentation in immune organs of aspartame treated animals;however,there was a significant increase in hsp70 expression,apart from significant alteration in bcl-2 and bax at both mRNA transcript and protein expression level in the immune organs of aspartame treated animals compared to controls.Hence,the results indicated that hsp70 levels increased in response to oxidative injury induced by aspartame metabolites;however,these metabolites did not induce apoptosis in the immune organs.Furthermore,detailed analyses are needed to elucidate the precise molecular mechanisms involved in these changes. | Arbind Kumar Choudhary Rathinasamy Sheela Devi | 2016 | The Journal of Biomedical Research2016，30，5： | 0 |
| 4 | 给新生儿补充维生素A对其早期死亡率的影响:印度南部社区的群体随机试验显示文摘目的:评定给新生儿补充维生素A对其6个月大时死亡率的影响。 设计:群体、随机、双盲、安慰剂对照试验。 地点:印度南部2个农村社区。 | Lakshmi Rahmathullah James M Tielsch R D Thulasiraj Joanne Katz Christian Coles Sheela Devi Rajeesh John Karthik Prakash A V Sadanand N Edwin C Kamaraj 吕小东 | 2004 | 英国医学杂志中文版2004，7，2： | 0 |
| 5 | Interdependence between electrical and magnetic properties of polycrystalline cobalt-substituted tungsten bronze multiferroic ceramics显示文摘Polycrystalline cobalt-substituted tungsten bronze ferroelectric ceramics with chemical composition Ba_(5)CaTi_(2-x)Co_(X)Nb_(8)O_(30)(x=0.00,0.02,0.04 and 0.08)were synthesized by solid state reaction technique.X-ray diffraction(XRD)technique was used to confirm the phase formation and it revealed the formation of single phase tetragonal structure with space group P4bm.The surface morphology of the samples was studied by using the scanning electron microscopy(SEM)technique.The dielectric properties such as dielectric constant and dielectric loss have been investigated as a function of temperature and frequency.The P-E and M-H studies confirmed the coexistent of ferroelectricity and magnetism at room temperature.The P-E loop study indicated an increase in the coercive field while the M-H study depicted a decrease in the magnetization with the incorporation of cobalt ions. | Shilpi Jindal Sheela Devi Ajay Vasishth Khalid Mujasam Batoo Gagan Kumar | 2018 | Journal of Advanced Dielectrics2018，8，1： | 0 |
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