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| 1 | Fourier Transform Infrared Spectroscopic Analysis of Protein Secondary Structures显示文摘红外线的光谱学是为多肽和蛋白质的二级结构的分析的最旧、好的确定的试验性的技术之一。它是方便的,非破坏性,要求更少的样品准备,和罐头在 ofconditions.This 评论介绍的一个宽变化下面被使用在 Fourier 的最近的开发转变红外线(FTIR ) 光谱学技术和它的应用到蛋白质结构的研究。在 FTIR 分光镜的乐队和蛋白质二级结构部件之间的 experimentals 杀死,数据分析,和关联被讨论。到分析, conformational 变化,结构的动力学和稳定性蛋白质学习的二级结构的 FTIR 的应用也被讨论。 | Jilie KONG Shaoning YU | 2007 | Acta Biochimica et Biophysica Sinica2007，39，8： | 81 |
| 2 | Evaluation of ecosystem services of Chinese pine forests in China显示文摘Evaluation of forest ecosystem services is a hot topic,both in China and at abroad,but it has not yet obtained a consistency of evaluation indicator systems and evaluation methods.Under the framework of evaluation criteria to be implemented for forest ecosystem services,years of consecutive observation data from Long Term Ecological Research Stations affiliated to Chinese Forest Ecosystem Research Network(CFERN),forest resource inventory and public data were applied to carry out a detailed and dynamic evaluation on the physical quantity and value of ecosystem services of Chinese pine forests in China.The results showed that the above services had the total value and unit value of 1144.9640 billion(1.1449640×10 12 )RMB and 52.074 thousand RMB per hectare per year,respectively during the 9th Five-year Plan(1996―2000),and of 1190.5461 billion RMB and 52.101 thousand RMB per hectare per year,respectively,during the 10th Five-year Plan(2001―2005).For Chinese pine forests,water conservation was 40.40 hundred million cubic meters annually,soil conservation was 67 million tons and C fixation 9 million tons annually,production of healthful negative ions was 1.96×10 20 , absorption of SO2 was 5.02 hundred million kilograms and dust-catching was 759.10 hundred million kilograms. Among the 15 provinces of China with Chinese pine forests,the biggest beneficiary from ecosystem services was Liaoning Province;while Hunan Province was the smallest beneficiary between the 9th Five-year Plan. | GUO Hao ,WANG Bing,MA XiangQian,ZHAO GuangDong&LI ShaoNing Research Institute of Forest Ecology Environment and Protection of CAF,Key Laboratory of Forest Ecological Environment of State Forestry Administration,Beijing 100091,China | 2008 | Science China(Life Sciences)2008，51，7： | 14 |
| 3 | Arsenic trioxide encapsulated liposomes prepared via copper acetate gradient loading method and its antitumor efficiency显示文摘In this study, arsenic trioxide(ATO) was encapsulated in liposomes via copper acetate(Cu(OAc)2) gradients and high entrapment efficiency of over 80% was obtained. The average particle size and the zeta-potential of the liposomes were detected to be 115.1 ± 29.1 nm and-21.97 ± 0.6 m V, respectively. The TEM images showed rod-like precipitates in the inner aqueous phase, which was supposed be due to the formation of insoluble ATO–Cu complex.The in vitro drug release of ATO–Cu liposomes exhibited a sustained release over 72 h, and the release rates decreased with the increase of the p H of release media. Pharmacokinetic and tissue distribution studies of ATO liposomes showed significantly reduced plasma clearance rate, increased AUC0–12h and T1/2, and improved tumor distribution of As compared to iv administration of ATO solution. The anti-tumor effect of ATO loaded liposomes to S180 tumor-bearing mice was significantly improved with a tumor inhibition rate of 61.2%,meanwhile the toxicity of encapsulated ATO was greatly decreased. In conclusion, ATO can be effectively encapsulated into liposomes by remote loading method via Cu(OAc)2 gradients;the co-administration of ATO and Cu(Ⅱ) via liposomal formulation may find wide applications in the treatment of various tumors. | Shaoning Wang Chunxiu Liu Cunyang Wang Jia Ma Hui Xu Jianbo Guo Yihui Deng | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，3： | 6 |
| 4 | Improved dissolution and oral absorption by co-grinding active drug probucol and ternary stabilizers mixtures with planetary beads-milling method显示文摘The objective of this work is to construct a nanosuspension drug delivery system of probucol,a BCS II drug,in order to improve its dissolution and oral bioavailability.The wet milling procedure using planetary beads-milling equipment was utilized to grind the raw probucol to ultrafine nanoparticle/nanocrystal aqueous suspension that was further solidified by freeze-drying process.Cellulose derivatives of different substitution groups and molecular weights,including HPMC,HPC,and MC,were evaluated as the primary stabilizer of probucol nanosuspension.Ternary stabilizers system composed of a primary stabilizer(cellulose derivative,i.e.HPC),a nonionic surfactant(Pluronic R F68),and an anionic surfactant(SDS)was employed to obtain probucol nanosuspension of finer particle size and enhanced dissolution in aqueous media.The probucol nanosuspension with good physical stability showed no obvious change of particle size even after storing over 7 d at 4°C or 25°C.The solidified probucol nanosuspension with trehalose as the cryoprotectant showed the highest dissolution rate(>60%at 2 h)compared to other cryoprotectant.The in vivo pharmacokinetic evaluation indicated about 15-folds higher AUC value of the probucol nanosuspension compared to that of coarse probucol suspension after oral administration to rats.The probucol nanosuspension prepared by wet-milling and ternary stabilizers system may find wide applications for improving the dissolution and oral absorption of water-insoluble drugs. | Fang Li Linsen Li Shaoning Wang Yan Yang Jia Li Dongchun Liu Sijie Zhang Siling Wang Hui Xu | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，6： | 5 |
| 5 | Heat transfer and fluid flow and their effects on the solidification microstructure in full-penetration laser welding of aluminum sheet显示文摘Understanding the behaviors of heat transfer and fluid flow in weld pool and their effects on the solidification microstructure are significant for performance improvement of laser welds.This paper develops a three-dimensional numerical model to understand the multi-physical processes such as heat transfer,melt convection and solidification behavior in full-penetration laser welding of thin 5083 aluminum sheet.Solidification parameters including temperature gradient G and solidification rate R,and their combined forms are evaluated to interpret solidification microstructure.The predicted weld dimensions and the microstructure morphology and scale agree well with experiments.Results indicate that heat conduction is the dominant mechanism of heat transfer in weld pool,and melt convection plays a critical role in microstructure scale.The mushy zone shape/size and solidification parameters can be modulated by changing process parameters.Dendritic structures form because of the low G/R value.The scale of dendritic structures can be reduced by increasing GR via decreasing heat input.The columnar to equiaxed transition is predicted quantitatively via the process related G^3/R.These findings illustrate how heat transfer and fluid flow affect the solidification parameters and hence the microstructure,and show how to improve microstructure by optimizing the process. | Shaoning Geng Ping Jiang Xinyu Shao Lingyu Guo Xuesong Gao | 2020 | Journal of Materials Science & Technology2020，42，11： | 5 |
| 6 | Recent Developments of Modulation and Control for High-Power Current-Source-Converters Fed Electric Machine Systems显示文摘The pulse-width-modulated(PWM)current-source converters(CSCs)fed electric machine systems can be considered as a type of high reliability energy conversion systems,since they work with the long-life DC-link inductor and offer high fault-tolerant capability for short-circuit faults.Besides,they provide motor friendly waveforms and four-quadrant operation ability.Therefore,they are suitable for high-power applications of fans,pumps,compressors and wind power generation.The purpose of this paper is to comprehensively review recent developments of key technologies on modulation and control of high-power(HP)PWM-CSC fed electric machines systems,including reduction of low-order current harmonics,suppression of inductor–capacitor(LC)resonance,mitigation of common-mode voltage(CMV)and control of modular PWM-CSC fed systems.In particular,recent work on the overlapping effects during commutation,LC resonance suppression under fault-tolerant operation and collaboration of modular PMW-CSCs are described.Both theoretical analysis and some results in simulations and experiments are presented.Finally,a brief discussion regarding the future trend of the HP CSC fed electric machines systems is presented. | Pengcheng Liu Zheng Wang Sanmin Wei Yuwen Bo Shaoning Pu | 2020 | CES Transactions on Electrical Machines and Systems2020，4，3： | 3 |
| 7 | Extended tacrolimus release via the combination of lipid-based solid dispersion and HPMC hydrogel matrix tablets显示文摘The objective of this study is to evaluate the feasibility of obtaining extended release of tacrolimus by a novel combination of lipid-based solid dispersion and matrix-type extended release tablet techniques. Tacrolimus solid dispersion was prepared using glycerylbehenate(Compritol~?ATO888) and Pluronic F127 as the carrier materials with hot-melt method, which was then blended with hydrogel matrix materials, such as HPMC and lactose, the powders were directly compressed into tablets. In vitro drug release tests were carried out to evaluate the performance of the solid dispersions and the tablets. The dissolution rate of tacrolimus was significantly improved by the lipid-based solid dispersion, and the incorporation of HPC into the solid dispersion obviously improved its stability after storage. Extended release tablets loaded with tacrolimus solid dispersion showed prolonged drug release patterns over 24 h, the release patterns of the tablets can be tailored by the compositions of the matrix materials, including the types and content of HPMCs. A modified processing method that directly mixed the melted solid dispersion with HPMC powders improved the uniformity of the solid dispersion inside the tablet matrix and release profile. The release data of the extended release tablet fitted well to the Korsmeyer–Peppas model with n value of 0.85, which suggested diffusion-and erosion-controlled release mechanism. The combination of lipid-based solid dispersion and HPMC hydrogel matrix may find wide applications in the extended release dosage forms of high potent, water-insoluble drugs. | Hui Xu Li Liu Xuehui Li Junyuan Ma Rui Liu Shaoning Wang | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，4： | 3 |
| 8 | Lithium in-diffusion treatment of thick LiNbO 3 crystals by the vapor transport equilibration method显示文摘 | Xinan Liang Xu Xuewu Chong Tow-Chong Yuan Shaoning Yu Fengliang Tay Yong Soon | 2003 | Journal of Crystal Growth2003，，： | 2 |
| 9 | Transductive Support Vector Machines and Applications in Bioinformatics for Promoter Recognition,Letters and Reviews显示文摘 | Nikola K Shaoning P | 2004 | Neural Information Processing2004，3，2： | 1 |
| 10 | Incremental Learning of Chunk Data for Online Pattern Classification Systems显示文摘 | Ozawa Seiiehi Pang Shaoning Kasabov Nikola | 2008 | IEEE Trans- actions on Neural Networks2008，19，6： | 1 |
| 11 | Constructing Support Vector Machine Ensemble显示文摘 | Kim H Pang Shaoning Jie Hongrno | 2003 | Pattern Recognition2003，36，12： | 1 |
| 12 | Transductive support vector machines and applications in bioinformatics for promoter recognition,letters and reviews显示文摘 | Nikola K Shaoning P | 2004 | Neural Information Processing2004，3，2： | 1 |
| 13 | Face membership au- thentication using SVM classification tree generated by membership- based LLE data partition显示文摘 | Pang Shaoning Kim Daijin Bang Sungyang | 2005 | IEEE Transactions on Neural Networks2005，16，2： | 1 |
| 14 | An OAIS based approach to effective long-term digital metadata curation 显示文摘 | Shaon A WoolfA | 2008 | Computer and lnformatiouScience2008，1，2： | 1 |
| 15 | Weighted average integration of sparse representation and collaborative representation for robust face recognition显示文摘Sparse representation is a significant method to perform image classification for face recognition. Sparsity of the image representation is the key factor for robust image classification.As an improvement to sparse representation-based classification, collaborative representation is a newer method for robust image classification. Training samples of all classes collaboratively contribute together to represent one single test sample. The ways of representing a test sample in sparse representation and collaborative representation are very different, so we propose a novel method to integrate both sparse and collaborative representations to provide improved results for robust face recognition.The method first computes a weighted average of the representation coefficients obtained from two conventional algorithms, and then uses it for classification. Experiments on several benchmark face databases show that our algorithm outperforms both sparse and collaborative representation-based classification algorithms, providing at least a 10%improvement in recognition accuracy. | Shaoning Zeng Yang Xiong | 2016 | Computational Visual Media2016，2，4： | 1 |
| 16 | Constructing Support Vector Machine Ensemble显示文摘 | Kim Hyun-Chul Pang Shaoning Je Hong-Mo | 2003 | Pattern Recognition2003，36，12： | 1 |
| 17 | Intradiscal cement leak following percutaneous vertebroplasty显示文摘 | Mirovsky Y Anekstein Y Shaon E | 2006 | Spine2006，31，10： | 1 |
| 18 | Three approaches to qualitative content anal- ysis显示文摘 | Hsieh HF Shaon SE | 2005 | Qualitative Health Research2005，15，9： | 1 |
| 19 | Face membership authentication using SVM classification tree generated by membership-based LLE data partition显示文摘 | Pang Shaoning Kim Daijin Bang Sungyang | | 0，，02： | 1 |
| 20 | Long-term Preservation for Spatial Data Infrastructures: a Metadata Framework and Geo-portal Implementation 显示文摘 | Arif Shaon Andrew Woolf | 2011 | D-Lib Magazine2011，17，910： | 1 |
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