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| 1 | Diagnostic non-invasive model of large risky esophageal varices in cirrhotic hepatitis C virus patients显示文摘AIM To build a diagnostic non-invasive model for screening of large varices in cirrhotic hepatitis C virus(HCV) patients. METHODS This study was conducted on 124 post-HCV cirrhotic patients presenting to the clinics of the Endemic Medicine Department at Mansoura University Hospital for evaluation before HCV antiviral therapy: 78 were Child A and 46 were Child B(score ≤ 8). Inclusion criteria for patients enrolled in this study was presence of cirrhotic HCV(diagnosed by either biopsy or fulfillment of clinical basis). Exclusion criteria consisted of patients with other etiologies of liver cirrhosis, e.g., hepatitis B virus and patients with high MELD score on transplant list. All patients were subjected to full medical record, full basic investigations, endoscopy, and computed tomography(CT), and then divided into groups with no varices, small varices, or large risky varices. In addition, values of Fibrosis-4 score(FIB-4), aminotransferase-to-platelet ratio index(APRI), and platelet count/splenic diameter ratio(PC/SD) were also calculated.RESULTS Detection of large varies is a multi-factorial process, affected by many variables. Choosing binary logistic regression, dependent factors were either large or small varices while independent factors included CT variables such coronary vein diameter, portal vein(PV) diameter, lieno-renal shunt and other laboratory noninvasive variables namely FIB-4, APRI, and platelet count/splenic diameter. Receiver operating characteristic(ROC) curve was plotted to determine the accuracy of non-invasive parameters for predicting the presence of large esophageal varices and the area under the ROC curve for each one of these parameters was obtained. A model was established and the best model for prediction of large risky esophageal varices used both PC/SD and PV diameter(75% accuracy), while the logistic model equation was shown to be(PV diameter ×-0.256) plus(PC/SD ×-0.006) plus(8.155). Values nearing 2 or more denote large varices.CONCLUSION This model equation has 86.9% sensitivity and 57.1% specificity, and would be of clinical applicability with 75% accuracy. | Hatem Elalfy Walid Elsherbiny Ashraf Abdel Rahman Dina Elhammady Shaker Wagih Shaltout Ayman Z Elsamanoudy Bassem El Deek | 2016 | World Journal of Hepatology2016,8,24: | 5 |
| 2 | Entrepreneurial Risk Taking in Family Firms显示文摘 | SHAKER A Z | 2005 | Family Business Review2005,18,1: | 1 |
| 3 | The immunostatus of T helper and T cytotoxie cells in the patients ten years after exposure to sulfur mustard显示文摘 | Shaker Z Hassan ZM Sohrabpoor H etal | 2003 | Immunopharmacol Immunotoxicol2003,25,3: | 1 |
| 4 | Contextual influences on the corporate entrepreneurship-performance relationship:A longitudinal analysis 显示文摘 | SHAKER A Z JEFFREY G C | 1995 | Journal of Business Venturing1995,10,1: | 1 |
| 5 | Study of omentinl and other adipokines and hormones in PCOS patients显示文摘 | Mahde A Shaker M A1-Mashhadani Z | 2009 | Oman Ned J2009,24,2: | 1 |
| 6 | A Measure of Absorptive Capacity: Scale Development and Validation显示文摘 | Tessa C F Andreas E Shaker A Z | 2011 | European Management Journal2011,29,2: | 1 |
| 7 | Contextualizing theory building in entrepreneurship research显示文摘 | SHAKER A Z | 2007 | Journal of Business Venturing2007,22,3: | 1 |
| 8 | The novel TLR9 antagonist COV08-O064 protects from ischemia/repeffusion injury in non-steatotic and steatotic mice livers显示文摘 | Shaker M E Trawick B N Mehal W Z | 2016 | Biochem Pharmacol2016,112,: | 1 |
| 9 | Develop- ment of anti ballistic board from ramie fiber显示文摘 | ALI Aidy SHAKER Z R KHALINA A | 2011 | Polymer- Plastics Technology and Engineering2011,50,62: | 1 |
| 10 | Sources of capabilities, integration and technology commercialization 显示文摘 | Shaker A Z Nielsen A P | 2002 | Strategic Management Journal2002,,23: | 1 |
| 11 | Analysis of terrain elevation effects on Ikonos imagery rectification accuracy by using non-rigorous models显示文摘 | Shi W Z Shaker A | 2003 | Photogrammetric Engineering and Remote Sensing2003,69,12: | 1 |
| 12 | Absorptive Capacity:a Review Recon- ceptualization and Extension 显示文摘 | SHAKER A Z GERARD G | 2002 | Academy of Management Review2002,27,2: | 1 |
| 13 | Epoxy - toughened, unsaturated polyester interpenetrating networks 显示文摘 | Shaker Z G Browne P M Stretz H A | 2002 | Journal of Applied Polymer Science2002,84,12: | 1 |
| 14 | Corporate Venturing and Value Creation: A Review and Proposed Framework 显示文摘 | NARAYANAN V K YANG Y SHAKER Z A | 2009 | Research Policy2009,38,1: | 1 |
| 15 | Effect of treat- ment with metforminon omentin-1, ghrelin and other biochemi- cal, clinical features in PCOS patients 显示文摘 | SHAKER M MASHHADANI Z I MEHDI A A | 2010 | Oman Med2010,25,4: | 1 |
| 16 | Internationalexpansion by new venture firms:international diversity,mode of market entry,technological learning,and per-formance显示文摘 | SHAKER A Z IRELAND R D HITT A M | 2000 | The Academy of Management Journal2000,43,5: | 1 |
| 17 | Technology strategy and new venture performanee: A study of corporate - sponsored and independent biotechnology ventures显示文摘 | Shaker A Z | 1996 | Journal of Business Venturing1996,11,4: | 1 |
| 18 | A typology of social entrepreners: Motives, search proces- ses and ethical challenges显示文摘 | Shaker A Z Gedajlovic E Donald O N | 2009 | Journal of Busines ses Venturing2009,24,5: | 1 |
| 19 | Technology strategy and financial performance: Examining the moderating role of the firm' s competitive environment 显示文摘 | Shaker A Z | 1996 | Journal of Business Venturing1996,11,3: | 1 |
| 20 | Technology strategy and software new ventures' performance: exploring the moderating effect of the competitive environment显示文摘 | Shaker A Z William C B | 2000 | Journal of Business Venturing2000,15,2: | 1 |