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| 1 | 吸烟,血清抗氧化维生素水平和老年性黄斑变性之间的关系(英文)显示文摘目的:研究老年性黄斑变性(AMD)等级、血清抗氧化维生素水平(维生素A、C和E)和吸烟的关系。方法:对84例患者行黄斑彩色眼底成像,根据AMD损伤率和损伤程度将其分为五组(等级I^V)。应用高效液相色谱法(HPLC)测量血清抗氧化维生素水平。根据吸烟状况分不吸烟者、已戒烟者和吸烟者三组,并统计吸烟者每年的吸烟总量。结果:对照组中,维生素A、E、C水平分别为0.874±0.326mg/L,10.739±4.874mg/L和1.737±0.447mg/L,AMD组中分别为0.880±0.305mg/L,9.487±6.060mg/L和1.870±2.191mg/L,无显著差异(P>0.05)。AMD不同等级分组间维生素A(P=0.881)和E(P=0.293)水平差异无统计学意义,维生素C水平(P=0.044)随AMD程度的加深而增加。根据吸烟状况,AMD组与对照组之间无显著差异。根据每年的吸烟总量,两组之间有显著差异(P=0.02)。AMD越严重,年吸烟总量越高(P=0.007)。结论:研究结果显示AMD与维生素A、E血清水平无关,但和维生素C的血清水平相关,并与吸烟量有关。 | Sezen Akkaya Cakir Ozlem Sahin Haluk Kazokoglu Feyza Tekeli Goncagul Haklar Yelda Ozkurt | 2014 | 国际眼科杂志2014，14，5： | 5 |
| 2 | Congenital H-type anovestibuler fistula显示文摘The congenital H-type fistula between the anorectum and genital tract besides a normal anus is a rare entity in the spectrum of anorectal anomalies. We described a girl with an anovestibuler H-type fistula and left vulvar abscess. A 40-day-old girl presented symptoms after her parents noted the presence of stool at the vestibulum. On the physical examination, anus was in normal location and size, and had normal sphincter tone. A vestibuler opening was seen in the midline just below of the hymen. A fistulous communication was found between the vestibuler opening and the anus, just above the dentate line. There was a vulvar abscess which had a left lateral vulvar drainage opening 15 mm left lateral to the perineum. After the management of local inflammation and abscess, the patient was operated for primary repair of the fistula. A protective colostomy wasn′t performed prior the operation. A profuse diarrhea started after 5 hours of postoperation. After the diarrhea, a recurrent fistula was occurred on the second postoperative day. A divided sigmoid colostomy was performed. 2 months later, and anterior sagital anorectoplasty was reconstructed and colostomy was closed 1 month later. Various surgical techniques with or without protective colostomy have been described for double termination repair. But there is no consensus regarding surgical management of double termination. | Mesut Yazlcl Barlas Etensel Harun Gürsoy Sezen zklsaclk | 2003 | World Journal of Gastroenterology2003，9，4： | 4 |
| 3 | Online computation of International Reference Ionosphere Extended to Plasmasphere(IRI-Plas) model for space weather显示文摘Ionosphere is the most challenging part of Space Weather with its spatio-temporal variability and dispersive nature. Ionospheric models are very important in reducing positioning error in GNSS system.International Reference Ionosphere(IRI) is an empirical, deterministic and climatic model of ionosphere up to 2000 km in height. Recently, IRI Extended to Plasmasphere(IRI-Plas) model has been developed to extend the interest region of IRI to the GPS orbital height of 20,000 km. Both IRI and IRI-Plas provide ionospheric parameters such as electron density, electron and ion temperatures according to their height profiles. In order to update the model to current ionospheric conditions, IRI-Plas can input F2 layer critical frequency(foF2), maximum ionization height(hmF2), and also Total Electron Content(TEC).Online IRI-Plas is developed for the ionospheric community to run multiple tasks at various locations,dates and times with optional foF2, hmF2 and TEC inputs in a user-friendly manner. In this paper, we are going to present the capabilities of the Online IRI-Plas service and provide some comparisons between IRI-Plas outputs and ionosonde measurements. The comparison between online IRI-Plas foF2 outputs and ionosonde foF2 measurements indicates that the model with TEC input can significantly improve the representation of the current ionospheric state, which is very successful especially in the geomagnetically disturbed days. | Umut Sezen T.L.Gulyaeva Feza Arikan | 2018 | Geodesy and Geodynamics2018，9，5： | 3 |
| 4 | Computational and Empirical Investigation of Propeller Tip Vortex Cavitation Noise显示文摘In this study,non-cavitating and cavitating flow around the benchmark DTMB 4119 model propeller are solved using both viscous and potential based solvers.Cavitating and non-cavitating propeller radiated noises are then predicted by using a hybrid method in which RANS(Reynolds-averaged Navier-Stokes)and FWH(Ffowcs Williams Hawkings)equations are solved together in open water conditions.Sheet cavitation on the propeller blades is modelled by using a VOF(Volume of Fiuld)method equipped with Schnerr-Sauer cavitation model.Nevertheless,tip vortex cavitation noise is estimated by using two different semi-empirical techniques,namely Tip Vortex Index(TVI,based on potential flow theory)and Tip Vortex Contribution(TVC).As the reference distance between noise source and receiver is not defined in open water case for TVI technique,one of the outputs of this study is to propose a reference distance for TVI technique by coupling two semi-empirical techniques and ITTC distance normalization.At the defined distance,the starting point of the tip vortex cavitation is determined for different advance ratios and cavitation numbers using potential flow solver.Also,it is examined that whether the hybrid method and potential flow solver give the same noise results at the inception point of tip vortex cavitation.Results show that TVI method based on potential flow theory is reliable and can practically be used to replace the hybrid method(RANS with FWH approach)when tip vortex cavitation starts. | Savas SEZEN Sakir BAL | 2020 | China Ocean Engineering2020，34，2： | 3 |
| 5 | Shear Strength Model for Lightly Reinforced Concrete Columns显示文摘 | Halil Sezen Jack P. Moehle | 2004 | Journal of Structural Engineering2004，，11： | 2 |
| 6 | Phase I study on the safety and preliminary efficacy of allogeneic mesenchymal stem cells in hypoxic-ischemic encephalopathy显示文摘BACKGROUND Hypoxic-ischemic encephalopathy(HIE)is a leading cause of morbidity and mortality in the adult as well as in the neonate,with limited options for treatment and significant dysfunctionality.AIM To investigate the safety and preliminary efficacy of allogeneic mesenchymal stem cells(MSCs)in HIE patients.METHODS Patients who had HIE for at least 6 mo along with significant dysfunction and disability were included.All patients were given Wharton’s jelly-derived MSCs at 1×106/kg intrathecally,intravenously,and intramuscularly twice a month for two months.The therapeutic effects and prognostic implications of MSCs were evaluated by multiple follow-ups.Functional independence measure(FIM),modified Ashworth,and Karnofsky scales were used to assess any side effects,neurological and cognitive functions,and overall outcomes.RESULTS The 8 subjects included in the study had a mean age of 33.25±10.18 years.Mean HIE exposure and mean post-HIE durations were 45.63±10.18 and 19.67±29.04 mo,respectively.Mean FIM score was 18.38±1.06,mean modified Ashworth score was 43.5±4.63,and mean Karnofsky score was 20.For the first 24 h,5 of the patients experienced a subfebrile state,accompanied by mild headaches due to intrathecally administration and muscle pain because of intramuscularly administration.Neurological and functional examinations,laboratory tests,electroencephalography,and magnetic resonance imaging were performed to assess safety of treatment.Mean FIM score increased by 20.88±3.31 in the first month(P=0.027)and by 31.38±14.69 in 12 mo(P=0.012).The rate of patients with an FIM score of 126 increased from 14.58%to 16.57%in the first month and 24.90%in 12 mo.CONCLUSION Multiple triple-route Wharton’s jelly-derived MSC administrations were found to be safe for HIE patients,indicating neurological and functional improvement.Based on the findings obtained here,further randomized and placebo research could be performed. | Serdar Kabataş ErdinçCivelek Necati Kaplan Eyüp Can Savrunlu Gülseli Berivan Sezen Mourat Chasan Halil Can Ali Genç Yener Akyuva Osman Boyalı Furkan Diren Erdal Karaoz | 2021 | World Journal of Experimental Medicine2021，11，2： | 2 |
| 7 | Subthreshold micropulse laser versus intravitreal anti-VEGF for diabetic macular edema patients with relatively better visual acuity显示文摘AIM:To compare the effects of yellow(577 nm)subthreshold micropulse laser(SML)and intravitreal(IV)anti-vascular endothelial growth factor(VEGF)treatment in patients with diabetic macular edema(DME)with relatively better visual acuity[best corrected visual acuity(BCVA)≤0.15 log MAR].METHODS:The medical records of 76 eyes of 47 patients underwent IV(0.5 mg)anti-VEGF injection or SML for the DME with relatively better BCVA were reviewed.The IV group received three consecutive monthly IV anti-VEGF injections,then were retreated as needed.The laser treatment group was treated at baseline and 3 mo,and then retreated at 6 and 9 mo if needed.All participants were followed up for one year.The mean BCVA and mean central macular thickness(CMT)values changes over the follow-up were evaluated.RESULTS:Twenty-four and 23 patients were assigned to the SML and IV subgroups,respectively.The mean number of treatments was 3.64±0.76 in SML group and 5.85±1.38 in IV group(P<0.05).The subgroups were similar with regard to the mean BCVA score at baseline and at the 1st and 3rd months,but the score of SML group was better than that of IV group at the 6th,9th,and 12th months(P<0.05).The decrease in the mean CMT values from baseline values was higher in SML group at the 6th,9th,and 12th months(P<0.05).CONCLUSION:Yellow SML treatment is superior to IV anti-VEGF injection in DME patients with relatively better BCVA for increasing visual acuity and decreasing CMT at 6,9,and 12 mo.SML can be a good alternative first-line therapy for DME with BCVA≤0.15 log MAR. | Sezen Akkaya Banu Acιkalιn Yusuf Emre Dogan Fatih Coban | 2020 | International Journal of Ophthalmology(English edition)2020，13，10： | 2 |
| 8 | Shear strength model for lightly reinforced concrete columns 显示文摘 | Halil Sezen and Jack P Moehle | 2004 | ASCE Journal of structural engineering2004，130，11： | 1 |
| 9 | Heavy metal accumulation and distribution in narrow-leavedcattail (Typhaangustifolia) and common reed(Phragmites austraBs)显示文摘 | AKSOY A DUMAN F SEZEN G | 2005 | Journal of Fresh-water Ecology2005，20，4： | 1 |
| 10 | Vitamin E and L-carnitine, separately or in combination,in the prevention of radiation-in- dueed brain and retinal damages显示文摘 | Sezen O Ertekin MV Demircan B | 2008 | Neurosurg Rev2008，31，2： | 1 |
| 11 | Reinforcement slip in reinforced concrete columns 显示文摘 | Sezen H Setzler E J | 2008 | ACI Structural Journal2008，105，3： | 1 |
| 12 | Evaluation of outcomes in patients given dexmedetomidine in functional endoscopic sinus surgery显示文摘 | Guven DG Demiraran Y Sezen G | 2011 | Ann Otol Rhinol Laryngol2011，120，9： | 1 |
| 13 | Behavior of square concrete columns reinforced with prefabricated cage system显示文摘 | SHAMSAI M SEZEN H | 2011 | Mate- rials and Structures2011，44，1： | 1 |
| 14 | Relative effects of design,integration and information sharing on supply chain performance显示文摘 | Sezen B | 2008 | Supply Chain management:An International Journal2008，13，3： | 1 |
| 15 | Comparison of drip and sprinkler irrigation strategies on sunflower seed and oil yield and quality under Mediterranean climatic conditions显示文摘 | Sezen S M Yazar A Kapur B | 2011 | Agri Water Manag2011，98，7： | 1 |
| 16 | Economic Evaluation of Reinforced Concrete Structures with Columns Reinforced with Prefabricated Cage System 显示文摘 | Mohammad Shamsai Earl Whitlateh Halil Sezen | 2007 | Journal of Construction Engineering and Management2007，133，11： | 1 |
| 17 | Anti - nociceptive, analgesic and pathohistological effects of intrathecal dexmedetomidine and bupivacaine in rats 显示文摘 | ERDIVANLI B ALTUN M SEZEN O K | 2013 | Rev Bras Anestesio12013，63，2： | 1 |
| 18 | Usefulness of the epicardial fat tissue thickness as a diagnostic criterion for geriatric patients with metabolic syndrome显示文摘ObjectiveTo 与新陈代谢的症候群(MetS ) 为衰老老人病人作为一个诊断标准评估 epicardial 脂肪织物厚度(EFTT ) 超过 65 岁的 .MethodsSixty 衰老老人病人为学习被招募。病人们被划分成二个组:组 1 (n = 30 ) 与 MetS 由病人组成了;组 2 (n = 30 ) 没有 MetS,由病人组成了。Echocardiography 被用来在所有病人测量 EFTT,并且血样品被分析让生物化学的 parameters.ResultsCompared 组织 2,组 1 的 EFTT 层次统计上更高(P <0.05 ) 。在二进制逻辑回归分析, EFTT 层次为新陈代谢的症候群用作独立因素(B = 17.35, SE = 4.93, Wald = 12.36, P <0.001 ) 。操作典型曲线(巨鸟曲线) 分析的接收装置表明 EFTT 在 7.3 公里的水平上面与 96.7% 敏感和 86.7% 特性预言了 MetS [在曲线 = 下面的区域 0.969;95% 信心间隔(CI ) :0.928-1.00 ] 学习表明了的在场的 .ConclusionsThe 浆液 EFTT 铺平,这在有 MetS 的衰老老人病人是更高的并且能因此为 MetS 被用作一个诊断标准。 | Bema Kaya Bedri Caner Kaya Emel Yigit Karakas Sadettin Selcuk Baysal Dursun Cadirci Emre Erkus Ibrahim Halil Altiparmak Emin Savik Hatice Sezen Tttrgay Ulas | 2015 | Journal of Geriatric Cardiology2015，12，4： | 1 |
| 19 | High-Strength Concrete Columns Reinforced with Prefabricated Cage System 显示文摘 | Halil Sezen Mohammad Shamsai | 2008 | Journal of Structural Engineering2008，134，5： | 1 |
| 20 | Cobalt-catalyzed arylation of azole heteroarenes via direct C-H bond functionalization显示文摘 | SEZEN B SAMES B | | 0，，20： | 1 |
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