|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Etiology and portal vein thrombosis in Budd-Chiari syndrome显示文摘AIM: To research the etiology, portal vein thrombosis and other features of Budd-Chiari syndrome (BCS) patients prospectively. METHODS: A total of 75 patients (40 female, 35 male) who were diagnosed between January 2002 and July 2004 as having BCS were studied prospectively. Findings from on physical examination, ultrasonography, duplex ultrasonography and venography were analyzed. Hemogram and blood chemistry were studied at the time of diagnosis and on each hospital visit. Bone marrow examination and immune phenotyping were performed by a hematologist when necessary. Protein C, S, antithrombin Ⅲ, activated protein C resistance, and anticardiolipin antibodies, antinuclear antibodies, and anti ds-DNA were studied twice. The presence of ascite, esophageal varices, and portal thrombosis were evaluated at admission and on every visit. RESULTS: At least one etiological factor was determined in 54 (72%) of the patients. The etiology could not be defined in 21 (28%) patients. One etiological factor was found in 39, 2 factors in 14 and 3 factors in 1 patient. The most common cause was the web (16%), the second was Hydatid disease (11%), the third was Behcet’s disease (9%). Portal vein thrombosis was present in 11 patients and at least one etiology was identified in 9 of them (82%). CONCLUSION: Behcet’s disease and hydatid disease are more prominent etiological factors in Turkey than in other countries. Patients with web have an excellent response to treatment without signs of portal veinthrombosis while patients having thrombofilic factors more than one are prone to develop portal vein thrombosis with worse clinical outcome. | Oguz Uskudar Meral Akdogan Nurgul Sasmaz Sevinc Yilmaz Muharrem Tola Burhan Sahin | 2008 | World Journal of Gastroenterology2008，14，18： | 14 |
| 2 | Intraoperative acidosis is a new predictor for postoperative pancreatic fistula after pancreaticoduodenectomy显示文摘BACKGROUND:Early diagnosis of postoperative pancreatic fistula(POPF) is important for proper interventions.The preoperative,intraoperative and early postoperative biochemical markers have predictive value of POPF.The present study was to evaluate several simple biochemical parameters in the prediction of POPF.METHODS:Patients who underwent pancreaticoduodenectomy in our center between 2006 and 2015 were reviewed retrospectively.Preoperative and early postoperative biochemical parameters were evaluated.Additionally,the relationship between POPF and p H and lactate level at the end of surgery were analyzed,and neutrophil-to-lymphocyte ratio(NLR),plateletto-lymphocyte ratio(PLR),and red cell distribution widthto-platelet ratio(RPR) were calculated for postoperative days(PODs) 1 and 3.Diagnosis and grading of POPF were performed according to the standards of the International Study Group on Pancreatic Fistula.The patients were divided into two groups:Group 1 with no fistula or grade-A fistula; group 2 with grade-B or-C fistula.These simple biochemical markers were then compared between the two groups.RESULTS:Serum amylase level was significantly higher at POD3,and p H level was significantly lower at the end of operation in group 2 compared with those in group 1.However,the serum amylase was below the upper limit of normal serum level and therefore,the difference was not significant in clinical practice.Receiver operating charecteristic curve analysis showed that p H level was a reliable predictor of POPF(area under the curve:0.713; 95% CI:0.573-0.853).CONCLUSIONS:A low p H level at the end of pancreaticoduodenectomy was a risk factor of POPF.NLR,PLR,and RPR had no predictive value of POPF after pancreaticoduodenectomy. | Erdem Kinaci Mert Mahsuni Sevinc Abdulkerim Ozakay Savas Bayrak Ekrem Cakar Serkan Sari | 2016 | Hepatobiliary & Pancreatic Diseases International2016，15，3： | 7 |
| 3 | Leptin levels in the differential diagnosis between benign and malignant ascites显示文摘AIM: To evaluate the role of leptin levels in the differential diagnosis of ascites. METHODS: Ascitic leptin, TNFα and serum leptin levels were measured in 77 patients with ascites (35 with malignancies, 30 cirrhosis and 12 tuberculosis). Control serum samples were obtained from 20 healthy subjects. Leptin and TNFα levels were measured by ELISA. Body mass index (BMI) and percentage of body fat (BFM) by skin fold measurement were calculated for all patients and control groups. Peritoneal biopsy, ascites cytology and cultures or biochemical values were used for the diagnosis of patients. RESULTS: In patients with malignancies, the mean serum and ascites leptin levels and their ratios were significantly decreased compared to the other patient groups and controls. In tuberculosis peritonitis, ascitic fluid TNFα levels were significantly higher than malignant ascites and cirrhotic sterile ascites. BMI and BFM values did not distinguish between patients and controls. CONCLUSION: In patients with malignant ascites, levels of leptin and TNFα were significantly lower than in patients with tuberculous ascites. | Mehmet Buyukberber Mehmet Koruk M Cemil Savas Murat T Gulsen Yavuz Pehlivan Rukiye Deveci Alper Sevinc Serdar Gergerlioglu | 2007 | World Journal of Gastroenterology2007，13，3： | 7 |
| 4 | Early detection of response to imatinib therapy for gastrointestinal stromal tumor by using 18F-FDG-positron emission tomography and computed tomography imaging显示文摘有变形胃肠的基质肿瘤的 41 年的老女性被指 18F-FDG-positron 排放断层摄影术和计算断层摄影术(PET/CT ) 与 imatinib 在一个月前后扫描治疗(Glivec 收款机, Gleevec 收款机, Novartis,巴塞尔,瑞士) ,一个酷氨酸激酶禁止者(400 mg/d ) 。新陈代谢的反应在一月治疗前后被评估。最大的 standardised 举起价值(SUV ) 的减少是 79%( 从 9.8 ~ 2.1 ) 。正电子排放断层摄影术在 imatinib 治疗的一个月以后表明了完全的新陈代谢的反应。另外,以前的损害与花冠相比是计算机化的 tomographic 图象。根据 CT 图象在在治疗前后的肿瘤的尺寸没有差别。然而,新陈代谢的活动被禁止。18F-FDG-PET 是为对在有胃肠的基质肿瘤的病人的一个月 imatinib 治疗的反应的察觉的一个珍贵方法。 | Sabri Zincirkeser Alper Sevinc M Emin Kalender Celalettin Camci | 2007 | World Journal of Gastroenterology2007，13，15： | 7 |
| 5 | Effect of sunitinib on metastatic gastrointestinal stromal tumor in patients with neurofibromatosis type 1: A case report显示文摘Gastrointestinal stromal tumor (GIST) represents the most common mesenchymal malignancy of the gastrointestinal (GI) tract. In neurofibromatosis (NF), the increased incidence of tumor needs to be considered even in non-symptomatic individuals. Patients with neurofibromatosis NF type 1 have an increased risk of developing GI tumors including rare types such as GIST. We report a case of GIST in a 53-year-old male patient with neurofibromatosis. The patient was diagnosed with NF four years ago and his medical history revealed that he was hospitalized 5 times with a provisional diagnosis of massive lower gastrointestinal bleeding. GIST was diagnosed at explorative laparotomy and the tumor was 21 cm × 13 cm × 7 cm in size. Immunohistochemical examination showed that vimentin, actin and CD117 were positive. Computerized tomography showed peritoneal implants three months later. Imatinib mesylate (600 mg/d) was initiated. However, control computerized tomography revealed liver and omental metastasis. The dosage was elevated to 800 mg/d. Despite high dosage, the progression of the metastatic lesions continued in the liver and omentum. The patient started oral sunitinib malate (Sutent? Pfizer Inc, New York, NY, USA) 50 mg per day for 4 consecutive weeks, followed by 2 wk off per treatment cycle. The metastatic lesions in the liver and omentum were decreased in size after four courses, suggesting that sunitinib is also an effective treatment modality for metastatic GIST in NF patients. | M Emin Kalender Alper Sevinc Ediz Tutar Akif Sirikci Celalettin Camci | 2007 | World Journal of Gastroenterology2007，13，18： | 5 |
| 6 | Clinical and hemodynamic profiles of elderly patients with pulmonary arterial hypertension: a single center, prospective study显示文摘sPulmonary 动脉的高血压(哼) 以前被认为主要影响幼仔的病,但是现在,它逐渐地也被认出在老。这研究的目的是比较诊断与的老对更年轻的病人的特征,并且定义影响他们的长期的 survival.MethodsIn 的预示的因素哼这未来的、单个中心研究,临床, echocardiographic ,血液动力学的特征,并且结果更年轻( 18-65 年)并且老( 65 年)有 precapillary 的权威的诊断的病人哼 119 个病人全部的 compared.ResultsA 在这研究被分析;43 是老的(吝啬的年龄:71.5 ? 灡牰灯楲瑡 ? 慣摮摩瑡 ? 景瀠汵潭慮祲愠瑲牥慩? 票数瑲湥楳湯 ? 灳 ' 虝娹娆 _ 敨慲祰椠 ? 汥敤汲 ? 慰楴湥獴眠瑩 ? 異浬湯牡 ? | Ebru Ozpelit Bahri Akdeniz Dilek Sezgin Can Sevinc Kemal Can Tertemiz Mehmet Emre Ozpelit Mustafa Baris Nezihi Baris | 2017 | Journal of Geriatric Cardiology2017，14，1： | 5 |
| 7 | Extraordinary cause of acute gastric dilatation and hepatic portal venous gas: Chronic use of synthetic cannabinoid显示文摘Addiction to synthetic cannabinoids(SCs) is a growing social and health problem worldwide. Chronic use of SCs may cause adverse effects in the gastrointestinal system. We describe a very rare case of acute gastric dilatation(AGD) and hepatic portal venous gas(HPVG),with findings of acute abdomen resulting from chronic use of a SC, Bonzai. AGD and HPVG were detected by computerized tomography examination. Patchy mucosal ischemia was seen in endoscopic examination. Despite the findings of an acute abdomen, a non-surgical approach with nasogastric decompression, antibiotic therapy, and close radiologic and endoscopic followup was preferred in the presented case. Clinical and radiologic findings decreased dramatically on the first day, and endoscopic findings gradually disappeared over 7 d. In conclusion, this case shows that chronic use of a SC may cause AGD and accompanying HPVG,which can be managed non-surgically despite the findings of acute abdomen. | Mert Mahsuni Sevinc Erdem Kinaci Savas Bayrak Aytul Hande Yardimci Ekrem Cakar Hasan Bektas | 2015 | World Journal of Gastroenterology2015，21，37： | 3 |
| 8 | Effect of growth hormone on small intestinal homeostasis relation to cellular mediators IGF-I and IGFBP-3显示文摘AIM:To evaluate the effects of growth hormone(GH) on the histology of small intestines which might be related to the role of insulin like growth factor(IGF)-I, IGF-binding protein 3(IGFBP-3)and its receptors. METHODS:Twelve week-old adult male Wistar albino rats were divided into two groups.The study group(n =10),received recombinant human growth hormone (rGH)at a dose of 2 mg/kg per day subcutaneously for 14 d and the control group(n=10)received physiologic serum.Paraffin sections of jejunum were stained with periodic acid shift(PAS)and hematoxylin and eosin(HE) for light microscopy.They were also examined for IGF-I, IGFBP-3 and IGF-receptor immunoreactivities.Staining intensity was graded semi-quantitatively using the HS- CORE. RESULTS:Goblet cells and the cells in crypt epitheliawere significantly increased in the study group compared to that of the control group.We have demonstrated an increase of IGF-I and IGFBP-3 immunoreactivities in surface epithelium of the small intestine by GH application.IGF-I receptor immunoreactivities of crypt,villous columnar cells,enteroendocrine cells and muscularis mucosae were also more strongly positive in the study group compared to those of in the control group. CONCLUSION:These findings confirm the important trophic and protective role of GH in the homeostasis of the small intestine.The trophic effect is mediated by an increase in IGF-I synthesis in the small intestine, but the protective effect is not related to IGF-I. | Betul Ersoy Kemal Ozbilgin Erhun Kasirga Sevinc Inan Senol Coskun Ibrahim Tuglu | 2009 | World Journal of Gastroenterology2009，15，43： | 2 |
| 9 | Effect of continuous lumbar traction on the size of herniated disc material in lumbar disc herniation显示文摘 | Bulent Ozturk Osman Hakan Gunduz Kursat Ozoran Sevinc Bostanoglu | 2006 | Rheumatology International2006，，7： | 2 |
| 10 | The relation between plasma endothelin-1 levels and metabolic control,risk factors,treatment modalities,and diabetic microangiopathy in patients with Type 2 diabetes mellitus显示文摘 | Ak G Buyukberber S Sevinc A | 2001 | Diabetes Complications2001，15，3： | 1 |
| 11 | Improvement of colonic healing by preoperative rectal irrigation with short-chain fatty acids in rats given radiotherapy显示文摘 | Terzi C Sevinc AI Kocdor H | 2004 | Dis Colon Rectum2004，47，12： | 1 |
| 12 | Cilazapril-induced pleural effusion:a case report and review of the literature 显示文摘 | Elif K Gaye U Sevinc SU | 2010 | Ann Thorac Med2010，5，3： | 1 |
| 13 | Entropy-based assessment of water quality monitoring networks显示文摘 | Sevinc Ozkul Nilgun B Harmnaciou Vijay P Singh | 2000 | Journal of Hydrologic Engineering2000，5，1： | 1 |
| 14 | The utility of lactate dehydrogenase isoenzyme pattern in the diagnostic evaluation of malignant and nonmalignant ascites显示文摘 | Sevinc A Sari R Fadillioglu E | 2005 | J Natl Med Assoc2005，97，1： | 1 |
| 15 | Studies on silica obtained from rice husk显示文摘 | YALCIN N SEVINC V | 2001 | Ceramics International2001，27，2： | 1 |
| 16 | Early switch from intravenous tooral antibiotics : guidelines and implementation in a large teaching hospital 显示文摘 | Sevinc F Prins JM Koopmans RP | 1999 | J Antimicrob Chemother1999，43，： | 1 |
| 17 | New natural observer applied to speed-sensorless DC servo and induction motors 显示文摘 | Bowes S Sevinc A Derrick Holliday | 2004 | IEEE Transactions on Industrial Electronics2004，51，5： | 1 |
| 18 | Trauma from instrumentation after non- surgical periodontal treatment with ultrasonic scalers and Nd: YAG laser 显示文摘 | Dilsiz A Sevinc S | 2015 | Acta Odontol Scand2015，73，2： | 1 |
| 19 | The expression of angiopoietins and their receptor Tie-2 in human prostate carcinoma显示文摘 | WURMBACH J H HAMMERER P SEVINC S | 2000 | Anticancer Res2000，20，： | 1 |
| 20 | Web of Science:A Unique Method of Cited Reference Searching显示文摘 | Alper Sevinc | 2004 | Journal of The National Medical Assoeiation2004，96，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员