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| 1 | Levels of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 in gastric cancer显示文摘AIM:To evaluate the levels of preoperative serum matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in gastric cancer.METHODS:One hundred gastric cancer patients who underwent gastrectomy were enrolled in this study.The serum concentrations of MMP-1 and TIMP-1 in these patients and in fifty healthy controls were determined using an enzyme-linked immunosorbent assay.RESULTS:Higher serum MMP-1 and TIMP-1 levels were observed in patients than in controls (P < 0.001).Serum MMP-1 and TIMP-1 levels were positively associated with morphological appearance,tumor size,depth of wall invasion,lymph node metastasis,liver metastasis,perineural invasion,and pathological stage.They were not significantly associated with age,gender,tumor location,or histological type.CONCLUSION:Increased MMP-1 and TIMP-1 were associated with gastric cancer.Although these markers are not good markers for diagnosis,these markers show in advanced gastric cancer. | Ozgur Kemik Ahu Sarbay Kemik Aziz Sümer Ahmet Cumhur Dulger Mine Adas Huseyin Begenik Ismail Hasirci Ozkan Yilmaz Sevim Purisa Erol Kisli Sefa Tuzun Cetin Kotan | 2011 | World Journal of Gastroenterology2011，17，16： | 10 |
| 2 | Gallbladder function and dynamics of bile flow in asymptomatic gallstone disease显示文摘AIM:To investigate the effects of gallbladder stones on motor functions of the gallbladder and the dynamics of bile flow in asymptomatic gallstone disease.METHODS:Quantitative hepatobiliary scintigraphy was performed to detect the parameters of gallbladder motor function [gallbladder ejection fraction(GBEF),gallbladder visualization time(GBVT),gallbladder time to peak activity(GBTmax),gallbladder half emptying time(GBT1/2),and transit time of bile to duodenum(TTBD)] in 24 patients with asymptomatic cholelithiasis who were diagnosed incidentally during routine abdominal ultrasonographic examination and 20 healthy subjects with normal gallbladder.RESULTS:Even though there was no significant difference in the clinical and laboratory parameters between the patient and control groups,all parameters of gallbladder function except TTBD were found to differ significantly between the two groups.GBEF in the patient group was decreased(P=0.000) and GBVT,GBTmax,GBT1/2 in the patient group were longer(P=0.000,P=0.015,P=0.001,respectively).CONCLUSION:Our results showed that even if there were not any clinical and laboratory findings,gallbladder filling and emptying could be impaired in patients with gallstone disease. | Sevim Süreyya eri Feride Meltem zbek Celal eri Bahattin Baykal Hasan Erol Eroglu Zeynep Baykal Mustafa Yildiz Semahat Saglam Ahmet Yesildag | 2009 | World Journal of Gastroenterology2009，15，22： | 8 |
| 3 | Effect of Abdominal Obesity on Insulin Resistance and the Components of the Metabolic Syndrome: Evidence Supporting Obesity as the Central Feature显示文摘 | ?avlan Türkoglu MD Belgin Süsleyici Duman PhD Demet Günay PhD Penbe ?agatay PhD Remzi ?zcan MD A Sevim Büyükdevrim MD | 2003 | Obesity Surgery2003，，5： | 1 |
| 4 | Ultrasoundguided versus'blind'intraparotid injections of botulinum toxin-A for the treatment of sialorrhoea in patients with Parkinson's disease显示文摘 | Dogu O Apaydin D Sevim S | | 0，，： | 1 |
| 5 | Prevalence of essential tremor:door-to-door neurologic exams in Mersin Province,Turkey显示文摘 | Sevim S Camdeviren H | 2003 | Neurology2003，61，12： | 1 |
| 6 | Biliary complications and their management in pediatric liver transplantations:one center's experience显示文摘 | Karakayali H Boyvat F Sevims S | 2005 | Transplantation Proc2005，37，7： | 1 |
| 7 | Soybean oil-based lubricants : a search for synergistic antioxidants 显示文摘 | Brajendra K S Joseph M P Sevim Z E | 2007 | Energy Fuels2007，21，4： | 1 |
| 8 | Effect of intra-vitreal bevacizumab injection before Ahmed glaucoma valve im-plantation in neovascular glaucoma 显示文摘 | Sevim MS Buttanri IB Kugu S Serin D Sevim S | 2013 | Ophthalmological2013，229，2： | 1 |
| 9 | Corneal endothelial cell loss inpost-penetrating keratoplasty,patients after cataract surgery:phacoemulsification versus planned extracapsular cataract extrac tion显示文摘 | Acar B T Buttanri I B Sevim M S | 2011 | Journal of Cataract and Refractive Surgery2011，37，29： | 1 |
| 10 | Knowledge and Attitudes of High School Students about AIDS:A Turkish Perspective显示文摘 | Sevim S | 2003 | Public Health Nursing2003，20，1： | 1 |
| 11 | A study on recovery of gold from decopperized anode slime显示文摘 | DONMEZ B SEVIM F COLAK S | 2001 | Chemical Engineering & Technology2001，24，： | 1 |
| 12 | Effect of intravitreal beva- cizumab injection before Ahmed glaucoma valve implantation in neovascular glaucoma显示文摘 | Sevim MS Buttanri IB Kugu S | 2013 | Ohthalmological2013，229，2： | 1 |
| 13 | The effect of two different methods of pe- ripheralvenous blood collection on pain reduction in neonates 显示文摘 | Emine E Sevim S | 2007 | Agri2007，19，2： | 1 |
| 14 | Correlation of anxiety and depression symptoms in patients with restless leg syndreme:a population based survey显示文摘 | Sevim S Degu O Kalaegasi H | 2004 | J Neurol Neuresurg Psychiatry2004，75，2： | 1 |
| 15 | Effect of intravitreal Bevaci- zumab injection before Ahmed glaucoma valve implantation in neo- vascular glaucoma 显示文摘 | Sevim MS Buttanri IB Kugu S ct al | 2013 | Ophthalmologica2013，229，2： | 1 |
| 16 | A study on recovery of gold from decopperized anode slime 显示文摘 | Donmez B Sevim F Colak S | 2001 | Chemical Engineering & Technology2001，24，： | 1 |
| 17 | Unexpectedly low prevalence and unusual characteristics of RLS in Mersin, Turkey显示文摘 | Sevim S Dogu O Camdeviren H | 2003 | Neurology2003，61，： | 1 |
| 18 | Effect of botulinum toxin type A on nasal symptoms in patients with allergic rhinitis: a double-blind, placebo-controlled clinical trial显示文摘 | Unal M Sevim S Dogu O | 2003 | Acta Otolaryngol2003，123，9： | 1 |
| 19 | Effect of IntravitrealBevacizumab Injection before Ahmed Glaucoma Valve Im-plantation in Neovascular Glaucoma显示文摘 | Sevim MS Buttanri IB Kugu S | 2013 | Ophthalmologica2013，229，2： | 1 |
| 20 | The impact of mean reversion model on portfolio investment strategies:Empirical evidence from emerging markets显示文摘 | Akarim Y. D Sevim S | | 0，，33： | 1 |
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