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43篇 您的检索式:作者名="Sentovich"
    题名 作者 年代 出处 被引量
1Impact of RAS and BRAF mutations on carcinoembryonic antigen production and pattern of colorectal metastases显示文摘AIM: To investigate the impact of RAS and BRAF mutations on the pattern of metastatic disease and carcinoembryonic antigen(CEA) production.METHODS: In this retrospective study, we investigated the impact of RAS and BRAF mutational status on pattern of metastatic disease and CEA production. Only patients presenting with a newly diagnosed metastatic colorectal cancer(CRC) were included. Patients' characteristics, primary tumor location, site of metastatic disease and CEA at presentation were compared between those with and without RAS and BRAF mutations.RESULTS: Among 174 patients, mutations in KRAS, NRAS and BRAF were detected in 47%, 3% and 6% respectively. RAS mutations(KRAS and NRAS) were more likely to be found in African American patients(87% vs 13%; P value = 0.0158). RAS mutations were associated with a higher likelihood of a normal CEA(< 5 ng/mL) at presentation. BRAF mutations were more likely to occur in females. We were not able to confirm any association between mutational status and site of metastatic disease at initial diagnosis.CONCLUSION: No association was found between RAS and BRAF mutations and sites of metastatic disease at the time of initial diagnosis in our cohort. Patients with RAS mutations were more likely to present with CEA levels < 5 ng/mL. These findings may have clinical implications on surveillance strategies for RAS mutant patients with earlier stages of CRC.may cho chie akiba cecilia lau david smith milhan telatar michelle afkhami stephen sentovich kurt melstrom marwan fakih 2016World Journal of Gastrointestinal Oncology2016,8,1:3
2Simultaneous dynamic proctography and peritoneography for pelvic floor disorders显示文摘Sentovich SM Rivela LJ Thorson AG 1995Dis Colon Rectom1995,38,2:1
3Simultaneous dynamic proctography and peritoneography for pelvic floor disorders 显示文摘 Rivela L J Thorson A G 1995Dis Colon Rectum1995,38,9:1
4Fibrin glue for all anal fistula 显示文摘STEPHEN M SENTOVICH MD 2001J Gastrointest Surg2001,5,2:1
5Fibrin glue for all anal fistulas: long term results 显示文摘SENTOVICH MD 2003Dis Colon Rectum2003,46,4:1
6Fibrin glue for all anal fistulas显示文摘Sentovich SM 2001J Gastrointest Surg2001,5,2:1
7Fibrin glue for all anal fistulas:Long-term results显示文摘Sentovich SM 2003Dis Colon Rectum2003,46,4:1
8Fibrin Glue for All Anal Fistulas显示文摘Stephen M Sentovich MD 2001J Gastrointest Sur g2001,5,:1
9Fibrin Glue forAll Anal Fistulas Lo g- Term Results显示文摘Sentovich SM 2003Dis Colon Rectum2003,46,:1
10Pitfalls and sources of error in staging rectal cancer with endorectal US显示文摘Kruskal JB Kane RA Sentovich SM 1997Radiographics1997,17,3:1
11Immediate Reconstruction of the Perineal Wound With Gracilis Muscle Flaps Following Abdominoperineal Resection and Intraoperative Radiation Therapy for Recurrent Carcinoma of the Rectum显示文摘David Shibata MD William Hyland MD Paul Busse MD PhD H. Katherine Kim MD Steven M. Sentovich MD Glenn Steele MD PhD Ronald Bleday MD 1999Annals of Surgical Oncology1999,,1:1
12Fibrin Glue for all anal fistulas Long-Term Results显示文摘Sentovich SM 2003Dis Colon Rectum2003,46,:1
13Fibrin glue for atl anal fistulas显示文摘Stephen M Sentovich MD 2001J Gastrointest Surg2001,5,2:1
14Fibrin glue for all anal fistulas:long-term results显示文摘Sentovich SM 2003Dis Colon Rectum2003,46,4:1
15Transjugular intrahepatic portosystemic shunt for treatment of bleeding ectopic varices with portal hypertension显示文摘David Shibata M.D. David P. Brophy M.D. Fredric D. Gordon M.D. Harry T. Anastopoulos M.D. Stephen M. Sentovich M.D. Dr. Ronald Bleday M.D 1999Diseases of the Colon & Rectum1999,,12:1
16Fibrin Glue for All Anal Fistulas log-Term Results 显示文摘Sentovich SM 2003Diseases of the C olon&Reetum2003,46,:1
17Fibrin glue for anal fistulas:long-term results显示文摘Sentovich SM 2003Dis Colon Rectum2003,46,:1
18Fibrin glue for all anal fistulas 显示文摘Sentovich SM 2001J Gstrointest Surg2001,5,2:1
19Diagnosing anal sphincter injury with transanal ultrasound and manometry 显示文摘 Blatchford GJ Rivela LJ 1997Dis Colon Rectum1997,40,12:1
20Fibrin glue for anal fistulas:long-term results显示文摘Sentovich SM 2003Dis Colon Rectum2003,46,4:1
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