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| 1 | Update on mesenchymal stem cell therapies for cartilage disorders显示文摘Cartilage disorders, including focal cartilage lesions, are among the most common clinical problems in orthopedic practice. Left untreated, large focal lesions may result in progression to osteoarthritis, with tremendous impact on the quality of life of affected individuals. Current management strategies have shown only a modest degree of success, while several upcoming interventions signify better outcomes in the future. Among these, stem cell therapies have been suggested as a promising new era for cartilage disorders. Certain characteristics of the stem cells, such as their potential to differentiate but also to support healing made them a fruitful candidate for lesions in cartilage, a tissue with poor healing capacity. The aim of this editorial is to provide an update on the recent advancements in the field of stem cell therapy for the management of focal cartilage defects. Our goal is to present recent basic science advances and to present the potential of the use of stem cells in novel clinical interventions towards enhancement of the treatment armamentarium for cartilage lesions. Furthermore, we highlight some thoughts for the future of cartilage regeneration and repair and to explore future perspectives for the next steps in the field. | Nikolaos K Paschos Mackenzie L Sennett | 2017 | World Journal of Orthopedics2017，8，12： | 2 |
| 2 | Clean double-walled carbon nanotubes synthesized by CVD显示文摘 | Li W Z Wen J G Sennett M | 2003 | Chem Phys Lett2003，368，： | 1 |
| 3 | Mesenchymal-epithelial interactions during hair follicle morphogenesis and cycling显示文摘 | Sennett R Rendl M | 2012 | Semin Cell Dev Biol2012，23，8： | 1 |
| 4 | Comparison of lateral release versus lateral release with medial soft-tissue realignment for the treatment of recurrent patellar instability:a systematic review显示文摘 | Ricchetti ET Mehta S Sennett BJ | 2007 | Arthroscopy2007，23，5： | 1 |
| 5 | Wnt/显示文摘 | Tsai SY Sennett R Rezza A | 2014 | Dev Biol2014，385，2： | 1 |
| 6 | Wnt/13-catenin signaling in dermal condensates is required for hair follicle formation显示文摘 | Tsai SY Sennett R Rezza A | 2014 | Dev Biol2014，385，2： | 1 |
| 7 | Treatment of chronic osteomyelitis complicating nonunion and segmental defects of the tibia with open cancellous bone graft,posterolateral bone graft,and soft-tissue transfer显示文摘 | Esterhai JL Jr Sennett B Gelb H | 1990 | J Trauma1990，30，1： | 1 |
| 8 | Mesenchymal-epithelial interactions during hair follicle morphogenesis and cycling 显示文摘 | Sennett R Rendl M | 2012 | Semin Cell Dev Biol2012，23，8： | 1 |
| 9 | Automated method for improving system performance of computer-aided diagnosis in breast ultrasound显示文摘 | Drukker K Sennett C A Giger M L | 2009 | IEEE Trans Med Imaging2009，28，1： | 1 |
| 10 | American shoulder and elbow surgeons standardized shoulder assessment form, patient self-report section reliablitiy, validity, and responsivenss显示文摘 | Michener LA Mcclure PW Sennett BI | 2002 | Shoulder Elbow Surg2002，11，6： | 1 |
| 11 | Direct 3-di- mensional measurement of scapular kinematics during dynam- ic movements in vivo显示文摘 | McClure PW Michener LA Sennett BJ | 2001 | J Shoulder Elbow Surg2001，10，3： | 1 |
| 12 | Treatment of ehronles teomyelitis complicating nonunion and segmental defects of the tibia with open eaneeHousbonegraft,posterol ateral bone graft,and soft tissue transfer显示文摘 | Esterhai JL Sennett B Gelb H | 1990 | Trauma1990，30，1： | 1 |
| 13 | American shoulder and el-bow surgeons standardized shoulder assessment form,patient self-re-port section reliablitiy,validity,and responsivenss显示文摘 | Michener LA Mcclure PW Sennett BI | 2002 | Shoulder ElbowSurg2002，11，6： | 1 |
| 14 | Adult stem cell niches: cellular and molecular components显示文摘 | Rezza A Sennett R Rendl M | 2014 | Curr Top Dev Biol2014，107，： | 1 |
| 15 | Wnt/p-catenin signaling in dermal condensates is required for hair follicle formation显示文摘 | Tsai S Y Sennett R Rezza A | 2014 | Develop Biol2014，385，2： | 1 |
| 16 | Treatment of chronic osteomyelitis complicating nonunion and segmental defects of thetibia with open cancellous bone graft, posterolateral bone graft, and soft-tissue transfer显示文摘 | Esterhai JL Jr Sennett B Gelb H | 1990 | J Trauma1990，30，1： | 1 |
| 17 | Automated method for improving system performance of computer-aided diagnosis in breast ultrasound显示文摘 | Drukker K Sennett CA Giger ML | | 0，，01： | 1 |
| 18 | Comparison of lat- eral release versus lateral release with medial soft - tissue realignmentfor the treatment of recurrent patellar instability : a systematic review显示文摘 | Ricchetti ET Mehta S Sennett B J | 2007 | Arthroseopy2007，23，5： | 1 |
| 19 | Combined anterior cruciate hgament and medial collateral ligament injuries in adolescents显示文摘 | Sankar WN Wells L Sennett BJ | 2006 | J Pediatr Orthop2006，26，6： | 1 |
| 20 | Mesenchymal-epithelial interactions during hair follicle morphogenesis and cycling显示文摘 | Sennett R Rendl M | 2012 | Semin Cell Dev Bioi2012，23，8： | 1 |
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