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| 1 | 糖尿病视网膜病变患者玻璃体样本中白细胞介素-8和肿瘤坏死因子-α水平(英文)显示文摘目的:测量糖尿病性视网膜病变(DR)行玻璃体切除术(PPV)患者玻璃体样品中白细胞介素-8(IL-8),肿瘤坏死因子-α(TNF-α)的水平,与对照组比较结果并探讨其对DR的影响。方法:将伊斯坦布尔Bilim大学眼科系的57例(57眼)DR患者和22例黄斑裂孔未伴有增生性玻璃体视网膜病变患者分为研究组和对照组。对所有79例患者行3切口,20G PPV。PPV手术眼内灌注前,用Vitrector抽吸0.5mL玻璃体样品并稀释。样品转至冷藏室,存放在-70℃。IL-8和TNF-α的测量结果用酶联免疫吸附法以pg/mL为单位计算。结果:DR患者玻璃体样本中IL-8水平[82.7891±74.08700(0.08-307.09)pg/mL]明显高于对照组患者[2.9805±3.77546(0.08-18.53)pg/mL](P<0.001)。同样,DR患者TNF-α水平[18.0007±13.90015(2.32-51.11)pg/mL]也显着高于对照组[1.7005±1.26949(0.1-5.17)pg/mL](P<0.001)。结论:在视网膜新生血管形成中起重要作用的TNF-α和作为炎症和血管生成介体的IL-8水平在DR患者玻璃体样本中明显高。 | Rifat Rasier Ozgur Artunay Uzay Gormus Erdal Yuzbasioglu Alper Sengul Amber Senel Kukner Murat Oncel Halil Bahcecioglu | 2013 | 国际眼科杂志2013，13，12： | 8 |
| 2 | Correlation of neutrophil/lymphocyte and platelet/lymphocyte ratio with visual acuity and macular thickness in age-related macular degeneration显示文摘AIM:To investigate the place of neutrophil-to-lymphocyte ratio(NLR) and platelet-to-lymphocyte ratio(PLR) in the diagnosis of and prognosis for neovascular age-related macular degeneration(AMD). METHODS:One hundred AMD patients and 100 healthy controls were included in the study. Blood samples were obtained from the venous blood, which is used for routine analysis, and these samples were subjected to complete blood count. NLR was defined as the neutrophil count divided by the number of lymphocytes, and PLR was defined as the platelet count divided by the number of lymphocytes. RESULTS:No statistically significant difference was observed between the two groups under consideration in terms of demographic features(P>0.05). The average NLR in the patient group was found to be significantly higher than that in the healthy control group(P<0.05). The average PLR was significantly higher in the patient group as compared to the control group(P<0.05). As best corrected visual acuity(BCVA) increased, both NLR and PLR decreased(significant negative correlations at 49.8% and 63.0%, respectively), whereas as central macular thickness(CMT) increased, both NLR and PLR increased(significant positive correlations at 59.3% and 70.0%, respectively).CONCLUSION:NLR and PLR levels are higher among neovascular AMD patients as compared to healthy control group. NLR and PLR levels were found to be inversely proportional to BCVA and directly proportional to CMT. | Elvan Alper Sengul Ozgur Artunay Alev Kockar Ceyda Afacan Rifat Rasier Palmet Gun Nazli Gul Yalcin Erdal Yuzbasioglu | 2017 | International Journal of Ophthalmology(English edition)2017，10，5： | 4 |
| 3 | Trauma induced thyroid storm complicated by multiple organ failure显示文摘 | Mehmet Kanbay Aysegul Sengul Nilgn Gvener | 2005 | Chinese Medical Journal2005，，11： | 2 |
| 4 | Modeling with Fractional Equations 显示文摘 | Atici F M Sengul S | 2010 | J Math Anal Appl2010，369，： | 1 |
| 5 | Association of MDR1 C3435T polymorphism with bipolar disorder in patients treated with valproic acid显示文摘 | Turgut G Kurt E Sengul C et a1 | 2009 | Mol Biol Rep2009，36，： | 1 |
| 6 | Beneficial effect of lisinopill plus telmisartan in patients with type 2 diabetes, microalbuminuria and hypertension 显示文摘 | Sengul AM Altuntas Y Kürklü A | 2006 | Diabetes Res Clin Praet2006，71，2： | 1 |
| 7 | Compositional, biochemical and textural changes during ripening of Tulum cheese made with different coagulants显示文摘 | SENGUL M ERKAYA T DERVIOLU M | 2014 | International Journal of Dairy Technology2014，67，3： | 1 |
| 8 | Pulmonary throm- boembolism due to paliperidone: report of 2 cases 显示文摘 | SENGUL MC KAYA K YILMAZ A | 2014 | Am J Emerg Meal2014，32，7： | 1 |
| 9 | Diversity Analysis of Single and Multiple Beamforming显示文摘 | Ersin Sengul Enis Akay Ender Ayanoglu | 2006 | IEEE Transactions on communications2006，54，06： | 1 |
| 10 | Epicardial adipose tissue:a review of physiology,pathophysiology,and clinical applications显示文摘 | Sengul C Ozveren O | 2013 | Anadolu Kardiyol Derg2013，13，3： | 1 |
| 11 | Urinary angiotensinogen level iscorrelated with proteinuria in renal transplant recipients 显示文摘 | Erdogmus S Sengul S Kocak S | 2013 | TransplantProc2013，45，3： | 1 |
| 12 | Uterine leiomyoma embolization : Role of power Doppler ultrasonography 显示文摘 | Hannah M Zeteroglu S Sengul M | 2003 | Tani Girisim Radyol2003，9，： | 1 |
| 13 | Tissue levels of adiponectin, turnout necrosis factor - alpha, soluble intercellular adhesion molecule - 1 and heart - type fatty acid - binding protein in human coronary atherosclerotic plaques显示文摘 | Karaduman M Sengul A Oktenli C | 2006 | Clin Endocrinol (Oxf)2006，64，2： | 1 |
| 14 | Effects of radiotherapy on different histopathological types of rectal carcinoma显示文摘 | Sengul N Wexner SD Woodhouse S | 2006 | Colorectal Dis2006，8，4： | 1 |
| 15 | Application of Box-Wilson experimental design method for the photo degradation of baker's yeast industry with UV/H2O2 and UV/H2O2/Fe (II) process显示文摘 | Catalkaya E C Sengul F | 2006 | Journal of Hazardous Materials2006，128，23： | 1 |
| 16 | Mycobacterium tuberculosis in- fection in renal transplant recipients 显示文摘 | Ergun I Ekmekci Y Sengul S | 2006 | Transplant Proc2006，38，5： | 1 |
| 17 | Comparisons of in - hospital and one year outcomes in patients with left ventricular ejection fractions 40%, 41% ,49% and 50% having percutaneous coronay revascularization显示文摘 | Keelan PC Johnston JM Koru- Sengul T | 2003 | Am J Cardiol2003，91，10： | 1 |
| 18 | Hemobilia and occult cystic ar- terystump bleeding显示文摘 | Cagli B Tuned SA Sengul E | 2011 | Prague Medttep2011，121，2： | 1 |
| 19 | Effect of expanded perlite on the mechanical properties and thermal conductivity of lightweight concrete显示文摘 | Ozkan Sengul Senem Azizi Filiz Karaosmanoglu Mehmet Ali Tasdemir | 2010 | Energy & Buildings2010，，2： | 1 |
| 20 | Clear cell adenocarcinoma of the urinary bladder显示文摘 | Kosem M Sengul E | 2005 | Scand J Urol Nephrol2005，39，1： | 1 |
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