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| 1 | molecular pathology of intraductal papillary mucinous neoplasms of the pancreas显示文摘Since the first description of intraductal papillary mucinous neoplasms(IPMNs)of the pancreas in the eighties,their identification has dramatically increased in the last decades,hand to hand with the improvements in diagnostic imaging and sampling techniques for the study of pancreatic diseases.However,the heterogeneity of IPMNs and their malignant potential make difficult the management of these lesions.The objective of this review is to identify the molecular characteristics of IPMNs in order to recognize potential markers for the discrimination of more aggressive IPMNs requiring surgical resection from benign IPMNs that could be observed.We briefly summarize recent research findings on the genetics and epigenetics of intraductal papillary mucinous neoplasms,identifying some genes,molecular mechanisms and cellular signaling pathways correlated to the pathogenesis of IPMNs and their progression to malignancy.The knowledge of molecular biology of IPMNs has impressively developed over the last few years.A great amount of genes functioning as oncogenes or tumor suppressor genes have been identified,in pancreatic juice or in blood or in the samples from the pancreatic resections,but further researches are required to use these informations for clinical intent,in order to better define the natural history of these diseases and to improve their management. | Marina Paini Stefano Crippa Stefano Partelli Filippo Scopelliti Domenico Tamburrino Andrea Baldoni Massimo Falconi | 2014 | World Journal of Gastroenterology2014，20，29： | 4 |
| 2 | Pancreatic fistula: definition and current problems显示文摘 | Giovanni Butturini Despoina Daskalaki Enrico Molinari Filippo Scopelliti Andrea Casarotto Claudio Bassi | 2008 | Journal of Hepato - Biliary - Pancreatic Surgery2008，，3： | 3 |
| 3 | Ultrasonically sculpted virtual relay lens for in situ microimaging显示文摘We demonstrate in situ non-invasive relay imaging through a medium without inserting physical optical components.We show that a virtual optical graded-index(GRIN)lens can be sculpted in the medium using in situ reconfigurable ultrasonic interference patterns to relay images through the medium.Ultrasonic wave patterns change the local density of the medium to sculpt a graded refractive index pattern normal to the direction of light propagation,which modulates the phase front of light,causing it to focus within the medium and effectively creating a virtual relay lens.We demonstrate the in situ relay imaging and resolving of small features(22μm)through a turbid medium(optical thickness=5.7 times the scattering mean free path),which is normally opaque.The focal distance and the numerical aperture of the sculpted optical GRIN lens can be tuned by changing the ultrasonic wave parameters.As an example,we experimentally demonstrate that the axial focal distance can be continuously scanned over a depth of 5.4mm in the modulated medium and that the numerical aperture can be tuned up to 21.5%.The interaction of ultrasonic waves and light can be mediated through different physical media,including turbid media,such as biological tissue,in which the ultrasonically sculpted GRIN lens can be used for relaying images of the underlying structures through the turbid medium,thus providing a potential alternative to implanting invasive endoscopes. | Matteo Giuseppe Scopelliti Maysamreza Chamanzar | 2019 | Light(Science & Applications)2019，8，1： | 2 |
| 4 | Highly luminescent,visible-emitting lanthanide macrocyclic chelates stable in water and derived from the cyclen framework显示文摘 | Zucchi G Ferrand A Scopelliti R | 2002 | Inorg Chem2002，41，9： | 1 |
| 5 | Pancreatic fistula: definition and current problems显示文摘 | Giovanni Butturini Despoina Daskalaki Enrico Molinari Filippo Scopelliti Andrea Casarotto Claudio Bassi | 2008 | Journal of Hepato - Biliary - Pancreatic Surgery2008，，3： | 1 |
| 6 | Oxidative stress and HIV infection:target pathways for novel therapies? 显示文摘 | Aquaro S Scopelliti F Pollicita M | 2008 | Future HIV Therapy2008，2，4： | 1 |
| 7 | Effect of a neuroprotective exercise protocol on oxidative state and BDNF levels in the rat hippocampus 显示文摘 | Fernanda Cechetti Ctntia Fochesatto Denise Scopel et al | 2008 | Brain Research2008，1188，： | 1 |
| 8 | Impact ofdirect sowing mulch-based cropping systems on soilcarbon,soil erosion and maize yield显示文摘 | Scopel E Findeling A Guerra E C | 2005 | AgronomyFor Sustainable Development2005，25，4： | 1 |
| 9 | Soil carbonstorage potential of direct seeding mulch-based crop-ping systems in the Cerrados of Brazil显示文摘 | Corbeels M Scopel E Cardoso A | 2006 | GlobalChange Biology2006，12，9： | 1 |
| 10 | Induction of extreme light sensitivity in buried weed seeds and its role in the percep- tion of soil cultivations显示文摘 | Scopel A L Ballar6 C L Sdnchez R A | 1991 | Plant Cell and Environment1991，14，： | 1 |
| 11 | Synthesis and characterisation of the water soluble bis- phosphine complex and an investigation of its cytotoxic effects 显示文摘 | RENFREW A K EGGER A E SCOPELLITI R | 2010 | Comptes Rendus Chim2010，13，： | 1 |
| 12 | Lanthanide helicates self-assembled in water: a new class of highly stable and luminescent dimetallic carboxylates 显示文摘 | Elhabiri M Scopelliti R Bulnzli J G | 1999 | Journal of the American Chemical Society1999，121，10： | 1 |
| 13 | The versatility of the free lateral arm flap in head and neck soft tissue reconstruction:clinical experience of 210 cases显示文摘 | Marques Faria JC Rodrigues ML Scopel GP | 2008 | Plast Reconstr Aesthet Surg2008，61，2： | 1 |
| 14 | Solar UV-B influences microfaunal community composition in a Tierra del Fuego peatland显示文摘 | Robson T M Pancotto V A Scopel A L | 2005 | Soil Biol Biochem2005，，37： | 1 |
| 15 | A five-coordinate iron center in the active site of-hydrogenase:Hints from a mod- el study显示文摘 | Chen D Scopelliti R Hu X | 2011 | Angew Chem lnt Ed2011，50，： | 1 |
| 16 | Soil carbon stocks under no- tillage mulch-based cropping systems in the Brazilian Cerrado: An on-farm synchronic assessment显示文摘 | Nero M S Scopel E Corbeels M | 2010 | Soil and Tillage Research2010，110，1： | 1 |
| 17 | Effect of a neuroprotective exercise protocol on oxidative state and BDNF levels in the rat hippocampus显示文摘 | CECHETTI F FOCHESATTO C SCOPEL D | | 0，，： | 1 |
| 18 | Reversible protonation of a thiolate ligand in an -hydrogenase model complex 显示文摘 | Chen D Scopelliti R Hu X | 2012 | Angew Chem Int Ed2012，51，： | 1 |
| 19 | Solar UV-B influences microfaunal community composition in a Tierra del Fuego peatland 显示文摘 | ROBSON T M PANCOTTO V A SCOPEL A L | 2005 | Soil Biology & Biochemistry2005，37，12： | 1 |
| 20 | Analysis of clinical pharmacist interventions in a tertiary teaching hospital in Bra zil显示文摘 | Reis WC Scopel CT Correr CJ | 2013 | Einstein(Sao Paulo)2013，11，2： | 1 |
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