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26篇 您的检索式：作者名="Scheurlen"

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	题名	作者	年代	出处	被引量
1	Psychiatric side effects of pegylated interferon alfa-2b as compared to conventional interferon alfa-2b in patients with chronic hepatitis C显示文摘AIM: To assess systematically the spectrum and extent of depressive symptoms comparing patient groups receiving peginterferon or conventional interferon.METHODS: Ninety-eight patients with chronic hepatitis C and interferon-based therapy (+ribavirin) were consecutively enrolled in a longitudinal study. Patients were treated with conventional interferon alfa-2b (48/98patients; 5 MIU interferon alfa-2b thrice weekly) or peginterferon alfa-2b (50/98 patients; 80-150 μgpeginterferon alfa-2b) in combination with weight-adapted ribavirin (800-1 200 mg/d). Repeated psychometric testing was performed before, three times during and once after antiviral therapy: Depression was evaluated by the Hospital Anxiety and Depression Scale (HADS), anger/hostility by the Symptom Checklist-90 Items Revised (SCL-90-R).RESULTS: Therapy with pegylated interferon alfa-2bproduces comparable scores for depression (ANOVA:P = 0.875) as compared to conventional interferon.Maximums of depression scores were even higher and cases of clinically relevant depression were frequent during therapy with peginterferon. Scores for anger/hostility were comparable for both therapy subgroups.CONCLUSION: Our findings suggest that the extent and frequency of depressive symptoms in total are not reduced by peginterferon. Monitoring and management of neuropsychiatric toxicity especially depression have to be considered as much as in antiviral therapy with unmodified interferon.	Michael R Kraus Arne Sch(a\|¨)fer Herbert Csef Michael Scheurlen	2005	World Journal of Gastroenterology2005，11，12：	5
2	Anti- Saccharomyces cerevisiae Antibodies in Inflammatory Bowel Disease: a Family Study显示文摘	F. Seibold O. Stich R. Hufnagl S. Kamil M. Scheurlen	2001	Scandinavian Journal of Gastroenterology2001，，：	1
3	Compliance with Therapy in Patients with Chronic Hepatitis C: Associations with Psychiatric Symptoms, Interpersonal Problems, and Mode of Acquisition显示文摘	Michael Rupert Kraus Arne Sch?fer Herbert Csef Hermann Faller Hubert M?rk Michael Scheurlen	2001	Digestive Diseases and Sciences2001，，10：	1
4	Phase II study of photodynamic therapy and metal stent as palliative treatment for nonresectable hilar cholangiocarcinoma显示文摘	Franz Ludwig Dumoulin Thomas Gerhardt Sybille Fuchs Christian Scheurlen Michael Neubrand Günter Layer Tilman Sauerbruch	2003	Gastrointestinal Endoscopy2003，，：	1
5	Neonatal mastocy- tosis with pachydermic bullous skin without c-Kit 816 mutation显示文摘	Walker T Von Komorowski G Scheurlen W	2006	Der- matology2006，212，1：	1
6	Risk stratification in medulloblastoma:screening for molecular markers显示文摘	Ebinger M Senf L Scheurlen W	2006	Klin Padiatr2006，218，3：	1
7	Cavernous transformation of the portal vein associated with common bile duct strictures:report of two cases显示文摘	Mork H Weber P Schmidt H Goerig RM Scheurlen M	1998	Gastrointest Endosc1998，47，1：	1
8	Gilbert disease and type Ⅰ and Ⅱ Crigler-Najjar syndrome due to mutations in the same UGT1A1 gene locus显示文摘	Kraemer D Scheurlen M	2002	Med Klin (Munich)2002，97，9：	1
9	Impaired Pancreatic Function in Patients with Crohn’s Disease With and Without Pancreatic Autoantibodies显示文摘	F. Seibold M. Scheurlen A. Müller H. Jenss P. Weber	1996	Journal of Clinical Gastroenterology1996，，3：	1
10	Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome显示文摘	Scheurlen WG Schwabe GC Joos S	1998	J Clin Oncol1998，16，：	1
11	Computation of turbulent evaporating spray,eulefian versus lagrangian pproach 显示文摘	Hallmann M Scheurlen M	1995	J of Engineering for Gas Turbine and Power1995，117，：	1
12	Chronic autoimmune thromboeytopenia/neutropenia in a boy with persistent parvovirus B19 infection 显示文摘	Scheurlen W Ramasubbu K Wachowski O	2001	J Clin Virol2001，20，3：	1
13	Long-term results and prognostic factors in the treatment of achalasia with botulinum toxin显示文摘	Neubrand M Scheurlen C Schepke M	2002	Endoscopy2002，34，7：	1
14	Growth factor a/b-FGF and PDGF have no effect on development of inflammatory tumor in chronic pancreatitis显示文摘	Scheurlen I Izbicki JR Sauer H	1998	Langenbecks Arch Chit Suppl Kongressbd1998，115，1：	1
15	Neonatal mastocytosis with pachydermic bullous skin without c-Kit 816 mutation显示文摘	Walker T von Komorowski G Scheurlen W Dorn-Beineke A Back W Bayerl C	2006	Dermatology2006，212，1：	1
16	Effect of olsalazine and mesalazine on human ileal and colonic (Na+ + K+)-ATPase显示文摘	C. Scheurlen H. Allgayer W. Kruis E. Erdmann T. Sauerbruch	1993	The Clinical Investigator1993，，4：	1
17	Long-term result and prognostic factors in the treatment of achalasia with botulinum toxin显示文摘	NEUBRAND M SCHEURLEN C SCHEPKE M	2002	Endoscopy2002，34，7：	1
18	Mycoplas- naa pneumoniac associated organising pneumonia in a 10 year old boy显示文摘	Wachowski O Demirakca S Mtiller KM Scheurlen W	2003	Arch Dis Child2003，88，3：	1
19	Comprehensive Cohort Study: an alternative to randomized consent design in a breast preservation trial显示文摘	Olschewski M Scheurlen H	1985	Methods Inf Med1985，24，3：	1
20	Chronic autoimmune thrombopenia/neutropenia in a boy with persistent parvovirus B19 infection显示文摘	Scheurlen W Ramasubbu K Wachowski O	2001	J Clin Virol2001，20，3：	1

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