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| 1 | Relationship between Crohn’s disease, infection with Mycobacterium avium subspecies paratuberculosis and SLC11A1 gene polymorphisms in Sardinian patients显示文摘AIM: To study the association between Crohn’s disease (CD), Mycobacterium avium subspecies paratubercu- losis (MAP), and genetic factors by examining the role of natural resistance-associated macrophage protein 1 (NRAMP1) gene polymorphisms (now SLC11A1) in Sar dinian patients with CD and controls. METHODS: Thirty-seven CD patients and 34 controls with no inflammatory bowel disease (IBD) were recruited at the University of Sassari after giving written con sent. Six SCL11A1 polymorphisms previously reported to be the most significantly associated with IBD were searched. M. paratuberculosis was identified by IS900 PCR and sequencing. Logistic regression was used to cal culate odds ratios (OR) for the associations among CD presence of MAP, and 6 loci described above. RESULTS: For the first time, a strong association was observed between polymorphisms at NRAMP1 locus 823C/T and CD. While CD was strongly associated withboth NRAMP1 and MAP, NRAMP1 polymorphisms and MAP themselves were not correlated. CONCLUSION: Combined with previous work on the NOD2/CARD15 gene, it is clear that the interplay of ge- netic, infectious, and immunologic factors in the etiology of CD is complex. | Leonardo A Sechi Maria Gazouli Lee E Sieswerda Paola Molicotti Niyaz Ahmed John Ikonomopoulos Antonio M Scanu Daniela Paccagnini Stefania Zanetti | 2006 | World Journal of Gastroenterology2006，12，44： | 3 |
| 2 | Lp(a)Lipoprotein-coping with heterogeneity显示文摘 | Scanu A M | 2003 | N EngL Med2003，349，20： | 1 |
| 3 | Ultra-fast adenosine 5'-triphosphate,adenosine 5'-diphosphate and adenosine 5'-monophosphate detection by pressure-assisted capillary electrophoresis UV detection 显示文摘 | Zinellu A Sotgia S Scanu B | 2010 | Electrophoresis2010，31，16： | 1 |
| 4 | Lopoproteim(a) and the atherothro,botic provess:mechanistic insights and cLinicaL impLications显示文摘 | Scanu A M | 2003 | Curr AtheroscLer Rep2003，5，： | 1 |
| 5 | Cytokine levels in humansynovial fluid during the different stages of acute gout: role oftransforming growth factor beta 1 in the resolution phase显示文摘 | Scanu A Oliviero F Ramonda R | 2012 | AnnRheum Dis2012，71，4： | 1 |
| 6 | Taurine determination by capillary electrophoresis with laser-induced fluorescence detection:from clinical field to quality food applications显示文摘 | ZINELLU A SOTTA S SCANU B | 2009 | Amino Acids2009，36，1： | 1 |
| 7 | Gout as autoinflammatorydisease: new mechanisms for more appropriated treatment targets显示文摘 | Punzi L Scanu A Ramonda R | 2012 | Autoimmun Rev2012，12，1： | 1 |
| 8 | Use of a reference material proposed by the International Federation of Clinical Chemistry and Laboratory Medicine to evaluate analytical methods for the determination of plasma lipoprotein(a)显示文摘 | Albers J J Scanu A M | 2000 | Clin Chem2000，46，12： | 1 |
| 9 | Serum high-density lipoprotein : effect of change in structure on activity of chicken adipose tissue lipase 显示文摘 | Scanu A | 1966 | Science1966，153，736： | 1 |
| 10 | Serum high-density lipoprotein: effect of change in structure on activity of chicken adipose tissue lipase显示文摘 | SCANU A | 1966 | Sci-ence1966，153，： | 1 |
| 11 | Effect of Triton on lipoprorein lipase of rat plasma 显示文摘 | Schotz M C Scanu A Page I H | 1957 | Amer J Physiol1957，188，： | 1 |
| 12 | Cytokine levels in human synovial fluid during the different stages of acute gout:role of transforming growth factor β1 in the resolution phase显示文摘 | Scanu A Oliviero F Ramonda R | | 0，，： | 1 |
| 13 | Gout as autoinflammatory disease:new mechanisms for more appropriated treatm enttargets 显示文摘 | Punzi L Scanu A Ramonda R | 2012 | Autoimmun Rev2012，12，1： | 1 |
| 14 | A rare variant of gallstone Ileus:bouveret′s syndrome显示文摘 | Fancellu A Niolu P Scanu AM | | 0，，04： | 1 |
| 15 | High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystals显示文摘 | Scanu A Oliviero F Gruaz L | | 0，，： | 1 |
| 16 | High-density lipoproteins inhibit urate crystal-induced inflammation in mice显示文摘 | Scanu A Luisetto R Oliviero F | 2015 | Annals of the rheumatic diseases2015，74，3： | 1 |
| 17 | Stimulated T cells generate microparticles,which mimi cellular contact activation of human monocytes:differential regulation of pro-and anti-inflammatory cytokine production by high-density lipoprotein显示文摘 | Scanu A Molnarfi N Brandt KJ | 2008 | J Leukocyte Biol2008，83，4： | 1 |
| 18 | Eveduation of non -covalent interactions between serum albumin and green tea cateehins by affinity capillary electrophoresis 显示文摘 | Zinellu A Sotgia S Scanu B | 2014 | Journal of Chromatography A2014，1367，： | 1 |
| 19 | Serum high-density lipoprotein: ef- fect of change in structure on activity of chicken adipose tissue lipase显示文摘 | Scanu A | 1966 | Science1966，153，736： | 1 |
| 20 | High-density lipopro- teins downregulate CCL2 production in human fibmblast-like synovioeytes stimulated by urate crystals 显示文摘 | Scanu A Oliviero F Gmaz L | 2010 | Arthritis Res Ther2010，12，： | 1 |
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