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| 1 | Neuroinflammation and comorbidities are frequently ignored factors in CNS pathology显示文摘Virtually all drug interventions that have been successful pre-clinically in experimental stroke have failed to prove their efficacy in a clinical setting. This could be partly explained by the complexity and heterogeneity of human diseases as well as the associated co-morbidities which may render neuroprotective drugs less efficacious in clinical practice. One aspect of crucial importance in the physiopathology of stroke which is not completely understood is neuroinflammation. At the present time, it is becoming evident that subtle, but continuous neuroinflammation can provide the ground for disorders such as cerebral small vessel disease. Moreover, advanced aging and a number of highly prevalent risk factors such as obesity, hypertension, diabetes and atherosclerosis could act as 'silent contributors' promoting a chronic proinflammatory state. This could aggravate the outcome of various pathological entities and can contribute to a number of subsequent post-stroke complications such as dementia, depression and neurodegeneration creating a pathological vicious cycle. Moreover, recent data suggests that the inflammatory process might be closely linked with multiple neurodegenerative pathways related to depression. In addition, pro-inflammatory cytokines could play a central role in the pathophysiology of both depression and dementia. | Raluca Elena Sandu Ana Maria Buga Adriana Uzoni Eugen Bogdan Petcu Aurel Popa-Wagner | 2015 | Neural Regeneration Research2015，10，9： | 6 |
| 2 | Infrared radiative drying--a process analysis in food engineering 显示文摘 | Sandu C | 1982 | Biotechnology Progress1982，，3： | 1 |
| 3 | Surgical treatment and outcome of cerebral cavernomas~a 10 years'experience 显示文摘 | Giovani A Sandu A Neaesu A | 2014 | Romanian Neurosurgery2014，21，4： | 1 |
| 4 | Magentic resonance imagine assessment of disc degeneration 10 years after antenior lumbar Interlexty fusion显示文摘 | Penta M Sandu A Praser RD | 1995 | Spine1995，20，： | 1 |
| 5 | Overexpression of torsinA in PC12 cells protects against toxicity显示文摘 | Shashidharan P Paris N Sandu D | 2004 | Journalof Neurochemistry2004，88，4： | 1 |
| 6 | Ensem- ble-based chemical data assimilation, h general ap- proach 显示文摘 | Constantinescu E M Sandu A Chai T | 2007 | Quarterly Journal of the Royal Meteoro- logical Society2007，133，626： | 1 |
| 7 | On the binding mechanism of CMC in Si negative electrodes for Li-ion batteries显示文摘 | LESTRIEZ B BAHRI S SANDU I | 2007 | Electrochemistry Communications2007，9，： | 1 |
| 8 | Orbital optic nerve gliomas in children with neurofibromatosis type l显示文摘 | Zeid JL Charrow J Sandu M | 2006 | J AAPOS2006，10，： | 1 |
| 9 | A g ene cluster on pA01 of Arthrobacter nicotinovorans involved in the deg- radation of the plant alkaloid nicotine: Cloning, purication and characterization of 2,6-dihydroxypyridine 3-hydroxy- lase显示文摘 | Baitsch D Sandu C Brandsch R et a l | 2001 | J Bacterial2001，183，： | 1 |
| 10 | Orbital optic nerve gliomas in children with neurofibmmatosis type 1 显示文摘 | Zeid JL Charrow J Sandu M | 2006 | J AAPOS2006，10，： | 1 |
| 11 | Protein identification and localization using mass spectrometry and staining tests in cross- sections of polychrome samples 显示文摘 | KUCKOVA S SANDU I C A CKHOVA M | 2013 | Journal of Cultural Heritage2013，14，： | 1 |
| 12 | A review of emission polarization 显示文摘 | Sandus O | 1965 | Applied Optfi:s1965，4，12： | 1 |
| 13 | Postconditioning: a new or old option after ischemic stroke?显示文摘 | Sandu N Schaller B | 2010 | Expert Rev Cardiovasc Ther2010，8，4： | 1 |
| 14 | Plasmids for nicotinedependent and independent gene expression in Arthrobocter nicotinovotans and other A rthrobacter species显示文摘 | SANDU C CHIRIBAU CB SACHELARU P | 2005 | Applied and environmental microbiology2005，71，12： | 1 |
| 15 | Supraclavicular flap in head and neck reconstruction: experience in 50 consecutive patients显示文摘 | Sandu K Monnier P Pasche P | 2012 | Eur Arch Oto- rhinolaryngol2012，269，4： | 1 |
| 16 | What is a quantifier? 显示文摘 | HINTIKKA J SANDU G | 1994 | Synthese1994，98，： | 1 |
| 17 | A polynomial chaos-based kalman filter approach for parameter estimation of mechanical systems 显示文摘 | Emmanuel D Blanchard Adrian Sandu | 2010 | Journal of Dynamic Systems Mea- surement and Control Transactions of the ASME2010，132，06： | 1 |
| 18 | Access Control Principles and Practice显示文摘 | Sandu R S Samaratiy P | 1994 | IEEE Communications Magazine1994，32，9： | 1 |
| 19 | Factors influencing the nitrification efficiency of fluidized bed filter with a plastic bead medium 显示文摘 | Sandu S I Boardman G D Watten B J | 2002 | Aquacuh Eng2002，26，： | 1 |
| 20 | Predicting air quality:Improvements through advanced methods to integrate models and measurements显示文摘 | Carmichael G R Sandu A Chai T | | 0，，07： | 1 |
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