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		题名	作者	年代	出处	被引量
	1	Gastrointestinal and Retroperitoneal Manifestations of Type 1 Neurofibromatosis显示文摘	Ursula Basile Giuseppe Cavallaro Andrea Polistena Sandra Giustini Gennaro Orlando Dario Cotesta Luigi Petramala Claudio Letizia Stefano Calvieri Giorgio Toma	2010	Journal of Gastrointestinal Surgery2010，，1：	1
	2	Surgical Management of Abdominal Manifestations of Type 1 Neurofibromatosis: Experience of a Single Center显示文摘	Cavallaro Giuseppe Basile Ursula Polistena Andrea Giustini Sandra Arena Rossella Scorsi Alessandro Zinnamosca Laura Letizia Claudio Calvieri Stefano De Toma Giorgio	2010	The American Surgeon2010，，4：	1
	3	Neuroretinal dysfunction in patients affected by neurofibromatosis type 1显示文摘AIM:To examine neuroretinal function by using the multifocal electroretinography(mf ERG)test in patients with neurofibromatosis type 1(NF1)without optic pathway gliomas(OPGs).METHODS:This study was conducted on 35 patients(35 eyes)with NF1 and 30 healthy subjects(30 eyes)for the control group.Each subject underwent a complete ophthalmological examination including spectral domainoptical coherence tomography(SD-OCT)and mf ERG.The 1.5-Tesla magnetic resonance imaging(MRI)scan of the brain was performed in NF1 patients to assess the presence of OPGs.All participants were recruited having a best corrected visual acuity(BCVA)of no less than 20/20 in each eye.The amplitude and implicit time of the P1 wave(first-order Kernel component)were evaluated on mf ERG.Data analysis was carried out in the two central degrees and in the four quadrants from two to 25 degrees of visual field.RESULTS:Statistically significant results were obtained for the P1 wave amplitudes in the 4 quadrants in NF1 patients compared to healthy controls,while the reduction was not significant in the 2 central degrees between the groups.A statistically significant difference was observed among the P1 wave amplitudes as recorded in the 4 quadrants within the NF1 group,with lower amplitudes detected in the nasal quadrants.No differences in the implicit times were recorded in the 2 central degrees and in the 4 quadrants as compared between NF1 patients and controls.CONCLUSION:Impaired neuroretinal function in NF1 patients is expressed in a decreased amplitude of the P1-wave between 2 and 25 central retinal degrees on mf ERG.Altered intracellular signal transduction due to abnormal neurofibromin-mediated cyclic adenosine monophosphate(c AMP)generation,can be involved.The possible use of mf ERG as subclinical retinal damage indicator has a potential utility in clinical practice for the follow-up of NF1 patients.	Antonietta Moramarco Luca Lucchino Fabiana Mallone Michela Marcelli Ludovico Alisi Vincenzo Roberti Sandra Giustini Alessandro Lambiase Marcella Nebbioso	2022	International Journal of Ophthalmology(English edition)2022，15，5：	0

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