|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification显示文摘MLL-AF4 熔化基因是在在婴儿的高风险的尖锐成淋巴细胞的白血病的一个特点 genomic 错误。尽管 MLL-AF4 在人的开发期间出生前地产生,这很好被建立,它在在 utero 的造血的开发的效果仍然保持未经勘探。我们创造了一个人特定的细胞的系统在 MLL-AF4-expressing 人的胚胎的干细胞(hESCs ) 学习早 hemato-endothelial 开发。介绍的功能的研究,同种细胞的分析和基因表示表明在 hESCs 的 MLL-AF4 的那表情有 phenotypic,功能并且基因表示影响。MLL-AF4 在 hESCs 充当全球 transcriptional 使活跃之物和 homeobox 基因表示的一个积极管理者。机能上地, MLL-AF4 从 hESCs 提高 hemogenic 先锋的说明,但是强烈损害进一步造血的承诺赞成 endothelial 房间命运。MLL-AF4 hESCs transcriptionally 被告知向对 endothelial 成熟敏感的 hemogenic 先锋区分,由联系到 vascular-endothelial 功能和早造血作用的主人基因的显著 upregulation 思考了。而且,我们报导那 MLL-AF4 表情不是足够的转变导出 hESC 的造血的房间。这个工作说明 hESCs 怎么可以提供唯一的卓见进人的开发并且推进我们理解白血病的熔化基因,知道出生前地产生,调整人的胚胎的造血的说明。 | Clara Bueno Rosa Montes Gustavo J Melen Verdnica Ramos-Mejia Pedro J Real Ver6nica Ayllo'n Laura Sanchez Gertmdis Ligero Inmaculada Gutierrez-Aranda Agustin F Femfindez Mario F Fraga Inmaculada Moreno-Gimeno Deborah Btlrks Maria del Carmen Plaza-Calonge Juan C Rodriguez-Manzaneque Pablo Menendez | 2012 | Cell Research2012，22，6： | 2 |
| 2 | Adult bone marrow stromal cells differentiate into neural cells in vitro显示文摘 | Sanchez Ramos J Song S Cardozo Pelaez F | | 0，，： | 2 |
| 3 | Bioshale FP6 European project: exploiting black shale ores using biotechnologies? 显示文摘 | D'HUGUES P NORRIS P R HALLBERG K SANCHEZ F LANGWALDT J GROTOWSKI A CHMIELEWSKI T GROUDEV S Bioshale consortium | 2007 | Minerals Engineering2007，21，： | 1 |
| 4 | Assessment of metal contamination in donana national park (spain) using crayfish (proeamburus elarkia) 显示文摘 | Sanchez Lopez F J Gil Garcia M D Martinez Vidal J | 2004 | Environmental Monitoring and Assessment2004，，93： | 1 |
| 5 | Aluminium foams as structured supports fur volatile organic compounds( VOCs )oxidation显示文摘 | Sanz O Echave F J Sanchez M | 2008 | Applied Catalysis: Genera2008，340，1： | 1 |
| 6 | A correlation between the pretransplantation MELD score and mortality in the first two years after liver transplantation显示文摘 | Onaca N N Levy M F Sanchez E Q | 2003 | Liver Transpl2003，9，： | 1 |
| 7 | Cross-linked nanocomposite polymer electrolytes reinforced with cellulose whiskers显示文摘 | Samir M Alloin F Sanchez J Y | 2004 | Macro molecules2004，37，13： | 1 |
| 8 | Heavy metals in sewage sludge amended soils determined by sequential extractions as afunction of incubation time of soils显示文摘 | SANCHEZ M J GARCfA D M LORENZO L F | 2007 | Geoderma2007，，142： | 1 |
| 9 | Ultra-trace determination of per- sistent organic pollutants in arctic ice using stir bar sorp- tive extraction and gas chromatography coupled to mass spectrometry 显示文摘 | Lacortea S Quintana J Taulera R Ventura F Tovar- Sanchez A Duarte CM | 2009 | J Chromatogr A2009，1216，49： | 1 |
| 10 | Environmental control of dormancy in weed seed banks in soil显示文摘 | BENECH ARMOLD R L SANCHEZ R A FORCELLA F | 2000 | Field Crops Research2000，67，： | 1 |
| 11 | Overexpression of FABP 7 in Down Syndrome Fetal Brain Is Associated with PKNOX1 Gene-dosage Imbalance 显示文摘 | Sanchez Font M F Bosch Comas A Marfany G | 2003 | Nuclei Acids Res2003，31，11： | 1 |
| 12 | Modeling quenching performance by the kuyucak method显示文摘 | Sarmiento Gustavo Sanchez Bugna Joaquin Fernandez Canale Lauralice C F | 2007 | Materials Science and Engineering2007，159，： | 1 |
| 13 | Adult bone marrow stromal cells differentiate into neural cells in vivo显示文摘 | Sanchez - Ramos J Song S Cardozo - Pelaez F | 2000 | Exp Neurol2000，164，： | 1 |
| 14 | Unlocking fungal cryptic natural products 显示文摘 | Chiang Y M Lee K H Sanchez J F Keller N P & Wang C C | 2009 | Nat Prod Commun2009，4，15： | 1 |
| 15 | Effect of temperature on the free radical scavenging ca- pacity of extracts from red and white grape pomace peel 显示文摘 | LARRAURI J A SANCHEZ - MORENO C SAURA - CALIXTO F | 1998 | J Agric Food Chem1998，46，7： | 1 |
| 16 | Asymmetric aldol reaction using immobilized proline on mesoporous support 显示文摘 | Calderon F Fernandez R Sanchez F | 2005 | Adv Synth Catal2005，347，： | 1 |
| 17 | Fast and selective determination of triterpenic compounds in olive leaves by liquid chromatography tandem mass spectrometry with multiple reaction monitoring after microwave-assisted extraction显示文摘 | SANCHEZ A N PRIEGO C F RUIZ J J | 2009 | Talanta2009，78，1： | 1 |
| 18 | Conductimetric immunosensor for atrazine detection based on antibodies labelled with gold nanoparticles 显示文摘 | Valeraa E Javier R Sanchez F J | 2008 | Sensors and Actuators B2008，134，1： | 1 |
| 19 | Assessment of CaCl2, NaNO3 and NH4NO3 ex traction procedures for the study of Cd, Cu, Pb and Zn extractability in contaminated soils显示文摘 | Pueyo M Lopex Sanchez J F Rauret G | 2004 | Analytica Chimica Acta2004，504，2： | 1 |
| 20 | Increase in quinolone resistance in a Haemophilus influenzae strain isolate from a patient with recurrent respiratory infections treated with ofloxacin显示文摘 | JORDI V RUIZ J SANCHEZ F | 1999 | Antimicrob Agents Chemother1999，43，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员