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| 1 | Pre-ischemia electro-acupuncture potentiates the expression of Bcl-2 and transforming growth factor-beta 1 in rat brains显示文摘The expression of the anti-apoptotic molecules Bcl-2 and transforming growth factor-beta 1 is known to confer protective effects on the cerebral ischemia-reperfusion injury.The current study investigated the expression levels of Bcl-2 and transforming growth factor-beta 1 in response to multiple pre-ischemia electro-acupuncture at acupoints Zusanli(ST36)and Fengchi(GB20) stimulation.Rats were divided into five groups:uninjured,control,non-acupoint,GB20 and ST36. Rats in the non-acupoint,GB20 and ST36 groups received 30 minutes(3 times or 18 times)of electro-acupuncture stimulation before experimental cerebral ischemia was induced.Bcl-2 and transforming growth factor-beta 1 were found to be significantly increased in the ST36 groups with either 3 or 18 electro-acupuncture treatments(P<0.05).The production was higher with 18 electro-acupuncture treatments in the ST36 groups(P<0.05).In the GB20 groups,significant increase was only observed in transforming growth factor-beta 1 with 18 electro-acupuncture treatments(P<0.05).No significant elevation of the level of transforming growth factor-beta 1 was observed in the non-acupoint groups.However,the production of Bcl-2 increased with 18 treatments in the non-acupoint groups(P<0.05).The data suggest that multiple pre-ischemia electro-acupuncture at ST36 was effective in conferring neuroprotective effect on the brain by means of upregulation of Bcl-2 and transforming growth factor-beta 1 and the effect was increase with the number of treatment. | Ka Keung Yip Samuel CL Lo Kwok-fai So Dora MY Poon Mason CP Leung | 2012 | Neural Regeneration Research2012，7，24： | 3 |
| 2 | Granulocyte colony stimulating factor does not induce long-term DNA instability in healthy peripheral blood stem cell donors 显示文摘 | Shapira MY KaspIer P Samuel S | 2003 | Am J Hematol2003，73，1： | 1 |
| 3 | Postlrau matic growth in Chinese cancer survivors显示文摘 | Samuel MY Ho Cecilia LW Chan Rainbow TH Ho | 2004 | Psycho Oneology2004，，13： | 1 |
| 4 | Social sharing of bereavement experience by Chinese bereaved persons in Hong Kong显示文摘 | Amyy MC Cecilia WC Samuel MY | 2007 | Death Studies2007，31，： | 1 |
| 5 | Wafer-level vapor cells filled with laser-actuated hermetic seals for integrated atomic devices显示文摘Atomic devices such as atomic clocks and optically-pumped magnetometers rely on the interrogation of atoms contained in a cell whose inner content has to meet high standards of purity and accuracy.Glass-blowing techniques and craftsmanship have evolved over many decades to achieve such standards in macroscopic vapor cells.With the emergence of chip-scale atomic devices,the need for miniaturization and mass fabrication has led to the adoption of microfabrication techniques to make millimeter-scale vapor cells.However,many shortcomings remain and no process has been able to match the quality and versatility of glass-blown cells.Here,we introduce a novel approach to structure,fill and seal microfabricated vapor cells inspired from the century-old approach of glass-blowing,through opening and closing single-use zero-leak microfabricated valves.These valves are actuated exclusively by laser,and operate in the same way as the“make-seals”and“break-seals”found in the filling apparatus of traditional cells.Such structures are employed to fill cesium vapor cells at the wafer-level.The make-seal structure consists of a glass membrane that can be locally heated and deflected to seal a microchannel.The break-seal is obtained by breaching a silicon wall between cavities.This new approach allows adapting processes previously restricted to glass-blown cells.It can also be extended to vacuum microelectronics and vacuum-packaging of micro-electro-mechanical systems(MEMS)devices. | Vincent Maurice Clément Carlé Shervin Keshavarzi Ravinder Chutani Samuel Queste Ludovic Gauthier-Manuel Jean-Marc Cote Rémy Vicarini Moustafa Abdel Hafiz Rodolphe Boudot Nicolas Passilly | 2022 | Microsystems & Nanoengineering2022，8，6： | 0 |
| 6 | High-finesse Fabry-Perot cavities with bidimensional Si_(3)N_(4) photonic-crystal slabs显示文摘Light scattering by a two-dimensional photonic-crystal slab(PCS)can result in marked interference effects associated with Fano resonances.Such devices offer appealing alternatives to distributed Bragg reflectors and filters for various applications,such as optical wavelength and polarization filters,reflectors,semiconductor lasers,photodetectors,bio-sensors and non-linear optical components.Suspended PCS also have natural applications in the field of optomechanics,where the mechanical modes of a suspended slab interact via radiation pressure with the optical field of a high-finesse cavity.The reflectivity and transmission properties of a defect-free suspended PCS around normal incidence can be used to couple out-of-plane mechanical modes to an optical field by integrating it in a free-space cavity.Here we demonstrate the successful implementation of a PCS reflector on a high-tensile stress Si_(3)N_(4) nanomembrane.We illustrate the physical process underlying the high reflectivity by measuring the photonic-crystal band diagram.Moreover,we introduce a clear theoretical description of the membrane scattering properties in the presence of optical losses.By embedding the PCS inside a high-finesse cavity,we fully characterize its optical properties.The spectrally,angular-and polarization-resolved measurements demonstrate the wide tunability of the membrane’s reflectivity,from nearly 0 to 99.9470±0.0025%,and show that material absorption is not the main source of optical loss.Moreover,the cavity storage time demonstrated in this work exceeds the mechanical period of low-order mechanical drum modes.This so-called resolved-sideband condition is a prerequisite to achieve quantum control of the mechanical resonator with light. | Xu Chen Clément Chardin Kevin Makles Charles Caër Sheon Chua Rémy Braive Isabelle Robert-Philip Tristan Briant Pierre-François Cohadon Antoine Heidmann Thibaut Jacqmin Samuel Deléglise | 2016 | Light(Science & Applications)2016，5，1： | 0 |
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