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| 1 | Autoimmune hepatitis显示文摘自体免疫的肝炎是忍耐的损失通常认为地引起到 hepatocytespecific autoantigens 的长期的肝疾病。它被女偏爱,提高的 aminotransferase 层次,自身抗体,增加的血球素或 IgG 层次和接口肝炎的活体检视证据描绘。它当前被划分成类型 1 和 2,基于自身抗体的表示。Autoantigenic epitopes 仅仅为不太经常的类型被识别了 2。尽管自体免疫的肝炎发生在童年,这评论在成年人集中于疾病。当特殊病征的 biomarkers 不在时,诊断要求临床、生物化学、血清学、组织学的特征的考虑,它被编纂了进验证诊断得分系统。因为许多特征也发生在另外的长期的肝疾病,这些得分系统帮助微分诊断的评估。新实践指南重新定义标准让宽恕在抑制免疫力的治疗上包括完全的生物化学、组织学的正规化。免疫力的抑制用泼尼松或氢化尼松和 azathioprine 最经常是成功的;然而,为非肝脏硬化症的病人的 budesonide 和 azathioprine 的联合提供明显的优点。没有通过标准免疫力的抑制的病人是其他的抑制免疫力的政体的候选人,然而,任何一个都没在使随机化的、控制审判选择被学习。有也的重叠症候群主要 sclerosing 胆管炎或主要胆汁的肝硬化发生在一个少数。肝移植为与尖锐的肝失败,严重地患心脏代偿失调的肝硬化或 hepatocellular 癌介绍的病人代表一种救生选择。移植接受者在为在 allograft 的周期性的自体免疫的肝炎的风险,并且 de novo 疾病可以在为另外的指示移植的病人发生。为 AIH 移植的病人也在风险为周期性或 de novo 煽动性的肠疾病。在我们 immunopathogenesis 的理解的进步应该导致特定的诊断、预示的 biomarkers 和新治疗学的策略的鉴定。 | Farhad Sahebjam John M. Vierling | 2015 | Frontiers of Medicine2015，9，2： | 17 |
| 2 | Direct acting antiviral therapy is curative for chronic hepatitis C/autoimmune hepatitis overlap syndrome显示文摘Autoimmune phenomena are common in patients with chronic hepatitis C. Management of chronic hepatitis C/autoimmune hepatitis syndrome has until recently been problematic due to the adverse effects of interferon on autoimmune processes and immunosuppression on viral replication. In this report we describe 3 patients with chronic hepatitis C/autoimmune hepatitis overlap syndrome who responded rapidly to direct acting antiviral therapy. The resolution of the autoimmune process supports a direct viral role in its pathophysiology. | Farhad Sahebjam Cristina H Hajdu Esther Nortey Samuel H Sigal | 2016 | World Journal of Hepatology2016，8，14： | 2 |
| 3 | Fourteen-year experience of prenata1 diagnosis of thalassemia in Iran显示文摘 | Najmabadi H Ghamari A Sahebjam F | 2006 | Community Genet2006，9，2： | 1 |
| 4 | Hyaluronidase 3 ( HYAL3 ) knockout mice do not display evidence of hyaluronan accumulation显示文摘 | Vasantha Atmuri Dianna C. Martin Richard Hemming Alex Gutsol Sharon Byers Solmaz Sahebjam James A. Thliveris John S. Mort Euridice Carmona Judy E. Anderson Shyamala Dakshinamurti Barbara Triggs-Raine | 2008 | Matrix Biology2008，，8： | 1 |
| 5 | Fourteen- year experience of prenatal diagnosis of thalassemia in Iran显示文摘 | Najmabadi H Ghamari A Sahebjam F | 2006 | Community Genet2006，9，2： | 1 |
| 6 | Pretreatment ADC histogram analysis is a predictive imaging biomarker for bevaeizumab treatment but not chemotherapy in recurrent glioblastoma显示文摘 | Ellingson BM Sahebjam S Kim H J | 2014 | AJNR Am J Neuroradiol2014，35，4： | 1 |
| 7 | Emerging biomarkers in glioblastoma显示文摘 | McNamara MG Sahebjam S Mason WP | 2013 | Cancers ( Basel )2013，5，3： | 1 |
| 8 | Lack of Tissue Inhibitor of Metalloproteinases-3 Results in an Enhanced Inflammatory Response in Antigen-Induced Arthritis显示文摘 | Mahmoodi M Sahebjam S Smookler D | 2005 | Am J Pathol2005，166，6： | 1 |
| 9 | Fourteen- year experience of prenatal diagnosis of thalassemia in Iran 显示文摘 | Najmabadi H Ghamari A Sahebjam F | 2006 | Cornmunity Genet2006，9，2： | 1 |
| 10 | Lack of tissue inhibit of metalloproteinases-3 results in an enhanced inflammatory response in antigen-induced arthritis显示文摘 | Mahmoodi M Sahebjam S Smookler D | 2005 | Am J Pathol2005，166，6： | 1 |
| 11 | Bevacizumab use for recurrent high-grade glioma at McGill University Hospital显示文摘 | Sahebjam S Garoufalis E Guiot M C | | 0，，02： | 1 |
| 12 | Bevacizumab use for recurrent high-grade glioma at McGill University Hospital 显示文摘 | Sahebjam S Garoufalis E Guiot MC | 2013 | Can J Neurol Sci2013，40，： | 1 |
| 13 | Fourteen-year ex-perience of prenatal diagnosis of thalassemia in Iran显示文摘 | Najmabadi H Ghamari A Sahebjam F | 2006 | CommunityGenet2006，9，2： | 1 |
| 14 | Increased collagen and aggrecan degradation with age in the joints of Timp3 ( / ) mice显示文摘 | SAHEBJAM S KHOKHA R MORT J S | 2007 | Arthritis Rheum2007，56，3： | 1 |
| 15 | Increased collagen and aggrecan degradation with age in the joints of TIMP-3 mice显示文摘 | Sahebjam S Khokha R Mort JS | | 0，，3： | 1 |
| 16 | Relationship between left atrial function and size and level of left ventricu- lar dyssynchrony in heart failure patients 显示文摘 | Sahebjam M Zoroufian A Sadeghian H | 2013 | Echoeardio- graphy2013，30，7： | 1 |
| 17 | Emerging biomarkers in glioblastoma 显示文摘 | McNamara MG Sahebjam S Mason WP | 2013 | Cancers (Basel)2013，5，3： | 1 |
| 18 | Bevacizuraab use for recurrent high-grade glioma at meG-ill university hospital显示文摘 | Sahebjam S Garoufalis E Ouiot MC | 2013 | Can J Neurol Sci2013，40，2： | 1 |
| 19 | Bevacizumab use for recurrent high-grade glioma at McGill University Hospital 显示文摘 | Sahebjam S Garoufalis E Guiot MC | 2013 | Can J Neurol Sci2013，40，2： | 1 |
| 20 | Fourteen -year expe- rience of prenatal diagnosis of thalassemia in iran 显示文摘 | Najmabadi H Ghamari A Sahebjam F | 2006 | Community Genet2006，9，2： | 1 |
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