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| 1 | The Metabolic Response of Arabidopsis Roots to Oxidative Stress is Distinct from that of Heterotrophic Cells in Culture and Highlights a Complex Relationship between the Levels of Transcripts, Metabolites, and Flux显示文摘新陈代谢的调整是一重要,但是糟糕理解,到氧化应力的植物的反应的部分。在以前的研究(巴斯斯特等, 2007 ) ,在到由甲蔡醌的氧化应力的正式就职的文化的 Arabidopsis 房间的新陈代谢的反应被描绘。紧急情况幸存策略在 anabolism 的主要新陈代谢大部分在哪个是下面调整的赞成被揭开分解代谢并且抗氧化剂新陈代谢。在整个植物纸巾的反应可能是不同的,我们因此调查了 Arabidopsis 根的反应到甲蔡醌处理,分析有主要以及第二等的新陈代谢的焦点的 transcriptome, metabolome 和关键新陈代谢的流动。用氧化还原作用敏感的 GFP,甲蔡醌引起氧化还原作用不安,这也被显示出,不是就在线粒体,而且在根的 cytosol 和质体。在里面开始的 30 ? 处理的 min,反应类似于房间文化:在 TCA 周期和氨基酸生合成的代谢物有减少, transcriptomic 反应被 DNA 规章的蛋白质的起来规定统治。在 2 和 6 以后 ? 处理的 h,根的反应对房间文化不同。代谢物层次没仍然保持沮丧,但是相反恢复并且在 pyruvate 的情况中,一些氨基酸和脂肪族的 glucosinolates 在控制层次上面显示出稳定的增加。然而,在中央碳新陈代谢的流动的主要变化都没被观察,新陈代谢的抄本主要独立于相应代谢物变化了。一起,结果建议根纸巾能在氧化抑制以后恢复新陈代谢的活动并且为 glycolysis 和氧化戊糖磷酸盐小径加亮潜在地重要的角色。 | Martin Lehmann Markus Schwarzlander Toshihiro Obata Supaart Sirikantaramas Meike Burow Carl Erik Olsen Takayuki Tohge Mark D. Fricker Birger Lindberg Moiler Alisdair R. Fernie Lee J. Sweetlove Miriam Laxa | 2009 | Molecular Plant2009，2，3： | 8 |
| 2 | Is There a Metabolic Requirement for Photorespiratory Enzyme Activities in Heterotrophic Tissues?显示文摘Dear Editor, Photorespiration is an essential metabolic process in leaves that facilitates recovery of carbon lost by the oxygenase reaction of Rubisco and avoids the accumulation of the toxic product,2-phosphoglycolate (2PG) of this reaction (Bauwe et al.,2012).However,there is also evidence to suggest that photorespiration has a more complex role during normal growth than the mere detoxification of 2PG and the recovery of 3-phosphoglycerate (3PGA) (Bauwe et al.,2012).The current view is that photorespiration is an essential mechanism to maintain optimal photosynthesis,normal growth,and development of oxygenic photosynthetic organisms in an oxygen-containing environment (Bauwe et al.,2012). | Adriano Nunes-Nesi Alexandra Florian Andrew Howden Kathrin Jahnke Stefan Timm Hermann Bauwe Lee Sweetlove Alisdair R. Fernie | 2014 | Molecular Plant2014，7，1： | 3 |
| 3 | Increased β-Cyanoalanine Nitrilase Activity Improves Cyanide Tolerance and Assimilation in Arabidopsis显示文摘植物自然地生产被快速的吸收的一个过程在他们的房间在底层维持的氰化物(CN ) 。然而,与象工业污染那样的活动联系的环境 CN 的高集中对植物有毒。因此对作为一条潜在的线路增加植物的 CN detoxification 能力到植物救治有兴趣。这里, Pseudomonas fluorescens -cyanoalanine nitrilase pinA 与相比的 Arabidopsis 幼苗 overexpressing 野类型并且为生长的一根 -cyanoalanine nitrilase 大美人线(Atnit4 ) 面对外长的 CN。在有 CN 的孵化以后, +PfpinA 幼苗增加了漂白与相比的根长度,增加的新鲜重量,和减少的叶野类型,显示增加了 CN 忍耐。没有 -cyanoalanine synthase 活动的增加,增加的忍耐被完成,在氰化物吸收小径的另外的酶,建议那项 nitrilase 活动是为氰化物 detoxification 的限制因素。用标记实验[13C ] KCN 证明改变的 CN 忍耐能被差别向改变的 -cyanoalanine nitrilase 活动引起的 Asn 从 CN 在流动解释。代谢物在 CN 处理以后介绍提供了新卓见进下游的新陈代谢,揭示由 photorespiratory 氮周期和芳香的氨基酸的累积的 Asn 的向前的新陈代谢。 | Brendan O'Leary GaU M. Preston Lee J. Sweetlove | 2014 | Molecular Plant2014，7，1： | 3 |
| 4 | The contribution of adenosine 5'-diphosphoglucose pyrophosphorylase to the control of starch synthesis in potato tubers显示文摘 | SWEETLOVE L J MULLER-ROEBER B WILLMIZER L | 1999 | Planta1999，209，： | 1 |
| 5 | Roles of reactive oxygen species and antioxidants in plant mitochondria显示文摘 | SWEETLOVE L J FOYER C H | 2004 | Advance in Photosynthesis and Resporation2004，17，： | 1 |
| 6 | The contribution of adenosine 5'-diphosphoglucose pyrophosphorylase to the control of starch synthesis in potato tubers显示文摘 | Sweetlove L J Muller-Roeber B Willmitzer L | 1999 | Planta1999，209，： | 1 |
| 7 | The control of source to sink carbon flux during tuber development in potato显示文摘 | Sweetlove L J Kossmann J Riesmeier J W | 1998 | Plant J1998，15，5： | 1 |
| 8 | Identification of mitochondrial protein complexes in Arabidopsis using two- dimensional blue-native polyacrylamide gel electrophoresis 显示文摘 | Giege P Sweetlove L J Leaver C J | 2003 | Plant Mol Biol Rep2003，21，2： | 1 |
| 9 | The impact of oxidative stress on Arabidopsis mitochondria显示文摘 | SWEETLOVE L J HEAZLEWOOD J L | 2002 | Plantjoumal2002，32，6： | 1 |
| 10 | Characterization of transgenic potato (Solanum tuberosum) tubers with increased ADPglucose pyrophosphorylase显示文摘 | SWEETLOVE L J BURRELL M M AP REES T | | 0，，02： | 1 |
| 11 | Starch metabolism in tubers of transgenic potato (Solanum tuberosum) with increased ADP-glucose pyrophosphorylase显示文摘 | SWEETLOVE L J BURRELL M M AP REES T | | 0，，02： | 1 |
| 12 | The contribution of adenosine 5- diphosphoglucose pyrophosphorylase to the control of starch synthesis in potato tubers显示文摘 | Sweetlove LJ Muller - Rober B Willmitzer L | 1999 | Planta1999，209，： | 1 |
| 13 | The contribution of a- denosine 5c- diphosphoglueose pyrophosphorylase to the control ofstarch synthesis in potato tubers显示文摘 | Sweetlove L J Muller-roeber B WiUmizer L | 1999 | Planta1999，209，： | 1 |
| 14 | Respiratory metabolism: glycolysis, the TCA cycle and mitochondrial electron transport显示文摘 | Alisdair R Fernie Fernando Carrari Lee J Sweetlove | 2004 | Current Opinion in Plant Biology2004，，3： | 1 |
| 15 | The mitochondrion:an integration point of cellularmetabolism and signaling显示文摘 | SWEETLOVE L J FAIT A NUNES-NESI A WILLIAMS T FERNIE A R | 2007 | Critical Reviews in Plant Sciences2007，26，： | 1 |
| 16 | Regulation of met- abolic networks: understanding metabolic com- plexity in the systems biology era显示文摘 | Sweetlove L J Fernie h R | 2005 | New Phytologist2005，168，1： | 1 |
| 17 | Monitoring the in vivo redox state of plant mitochontria:effect of respiratory inhibitors,abiotic stress and assessment of recovery from oxidative challenge显示文摘 | SCHWARZL (A)NDER M FRICKER M D SWEETLOVE L J | 2009 | Bioehim Biophys Acta Bioenerg2009，1787，： | 1 |
| 18 | The contribution of adenosine 5'-diphosphoglucose pyrophosp-horylase to the control of starch synthesis in potato tubers 显示文摘 | Sweetlove L J Muller R B Willmizer L | 1999 | Planta1999，，209： | 1 |
| 19 | The impact of oxidative stress on Arabidopsis mitochondria显示文摘 | Sweetlove L Heazlewood J Herald V | 2002 | Plant J2002，32，6： | 1 |
| 20 | Starch metabolism in tubers of transgenic potato (Solanum tuberosum)with increased ADPglucose pyrophosphorylase显示文摘 | Sweetlove L J Burrell M M | | 0，，： | 1 |
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