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| 1 | A submillimeter observation and study of star-forming regions显示文摘Using the 3-m radio telescope of KOSMA, we mapped 12CO (J = 3-2) lines for three molecular clouds, B35, S146 and TMC-2A. High-velocity molecular outflows are found in all these regions. The physical and dynamical pa-rameters of the outflows are derived, and their shapes and driving sources are analyzed. Contour maps of center veloci-ties show that the large scale systematic gradients exist in the three clouds. These observed motions are best explained by rotation after excluding the cause of outflows. Furthermore, in the core region of TMC-2A there is a velocity gradient in opposite direction from that of the large scale. It may be caused by magnetic braking. Finally, angular velocities of the clouds are calculated, and the effects of rotation against gravity and lowering the star-formation rate are also ana-lyzed. | JIANG Linhua, WU Yuefang & M. MillerDepartment of Astronomy, Peking University, Beijing 100871, China Chinese Academy of Sciences-Peking University Joint Beijing Astrophysics Center, Beijing 100871, China I. Physikalisches Institut, Zulpicher Str | 2002 | Chinese Science Bulletin2002，47，1： | 8 |
| 2 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 3 | Severe adverse events during antiviral therapy in hepatitis C virus cirrhotic patients: A systematic review显示文摘AIM: To identify severe adverse events (SAEs) leading to treatment discontinuation that occur during antiviral therapy in hepatitis C virus (HCV)-infected cirrhotic patients. METHODS: We identified all the articles published prior to December 2011 in the PubMed, Medline, Lilacs, Scopus, Ovid, EMBASE, Cochrane and Medscape databases that presented these data in cirrhotic patients. These studies evaluated the rate of SAEs leading to discontinuation of standard care treatment: Pegylated interferon (PegIFN) alpha 2a (135-180 μg/wk) or PegIFN alpha 2b (1 or 1.5 μg/kg per week) and ribavirin (800-1200 mg/d). Patients with genotype 1 + 4 underwent treatment for 48 wk, whereas those with genotypes 2 + 3 were treated for 24 wk.RESULTS: We included 17 papers in this review, comprising of 1133 patients. Treatment was discontinued due to SAEs in 14.5% of the patients. The most common SAEs were: severe thrombocytopenia and/or neutropenia (23.2%), psychiatric disorders (15.5%), decompensation of liver cirrhosis (12.1%) and severe anemia (11.2%). The proportion of patients who needed to discontinue their therapy due to SAEs was significantly higher in patients with Child-Pugh class B and Cvs those with Child-Pugh class A: 22%vs 11.4% (P = 0.003). A similar discontinuation rate was found in cirrhotic patients treated with PegIFN alpha 2a and those treated with PegIFN alpha 2b, in combination with ribavirin: 14.2%vs 13.7% (P = 0.96). The overall sustained virological response rate in cirrhotic patients was 37% (95%CI: 33.5-43.1) but was significantly lower in patients with genotype 1 + 4 than in those with genotype 2 + 3: 20.5% (95%CI: 17.9-24.8) vs 56.5% (95%CI: 51.5-63.2), (P < 0.0001). CONCLUSION: Fourteen point five percent of HCV cirrhotic patients treated with PegIFN and ribavirin needed early discontinuation of therapy due to SAEs, the most common cause being hematological disorders. | Simona Bota Ioan Sporea Roxana Sirli Alina Popescu Adriana Maria Neghinǎ Mirela Dǎnilǎ Mihnea Strǎin | 2013 | World Journal of Hepatology2013，5，3： | 6 |
| 4 | Balloon kyphoplasty compared to vertebroplasty and nonsurgical management in patients hospitalised with acute osteoporotic vertebral compression fracture: a UK cost-effectiveness analysis显示文摘 | A. Svedbom L. Alvares C. Cooper D. Marsh O. Str?m | 2013 | Osteoporosis International2013，，1： | 5 |
| 5 | Life-cycle Assessment of Carbon Dioxide Capture for Enhanced Oil Recovery显示文摘技术是的二氧化碳俘获和存储( CCS )的发展和推广挪威的政府工程的气候 strategy.A 数字的一块奠基石当前沿着挪威的韦斯特海岸被评估/计划,在从这个工程的 Tjeldbergodden.CO2 的将在 Halten 油田为提高的油的回收部分地被利用,在挪威的海。我们学习如此的 system.A 的一个潜在的图案有 832 MW 的粗野权力产量的联合周期动力厂作为溶剂用胺基于燃烧以后的俘获与 CO2 俘获植物被相结合。捕获的 CO2 被用于提高的油的回收(EOR ) 。我们采用一个混合生命周期评价(LCA ) 估计系统的环境影响的方法。站台的修正和操作的学习焦点在 EOR.We 期间分配连接到 CO2 的俘获到连接到 CO2 的运输和存储到生产的油的电生产,和影响的影响。我们的学习由 80% ~ 75 g ·(kW · h 从权力生产显示出温室气体排出物的实质的减小)^(-1) 。它也显示与采油每单位量油生产了联系的排出物的减小,主要由于增加的采油。如果另外的力量需求从陆地由于 EOR 导致电源,减小是特别重要的。 | Edgar G. Hertwich Martin Aaberg Bhawna Singh Anders H. StrФmman | 2008 | Chinese Journal of Chemical Engineering2008，16，3： | 4 |
| 6 | Effect of hypnotherapy and educational intervention on brain response to visceral stimulus in the irritable bowel syndrome显示文摘 | M. B. O. Lowén E. A. Mayer M. Sj?berg K. Tillisch B. Naliboff J. Labus P. Lundberg M. Str?m M. Engstr?m S. A. Walter | 2013 | Aliment Pharmacol Ther2013，，12： | 4 |
| 7 | 应用两种不同数字图像分析法对沥青裹覆集料的检测与评价显示文摘集料与沥青的黏附性是影响道路耐久性最重要的因素之一。该文应用数字图像分析法估测沥青裹覆度替代人工预估法来评价黏附性。该方法为镜面反射量法,基于沥青反射光强度高于集料的特点,可用于估测所有颜色的集料。为了尽可能多地获取来自四分之一圆周弧形光源内的镜面反射量,随着旋转台的转动,拍摄不同角度的图像,并检测反射量用于估测沥青裹覆度。为了能够将研究结果与实际情况相比较,应用该方法对浅色集料进行评价,并与传统人工方法、评价浅色集料工作性优异的像素分割法进行比较。结果表明:传统人工方法离散性较大,难以准确估测;该方法测得的沥青裹覆度,接近像素分割法测值,但其值偏低;选取最优系数k的最小函数法计算补偿处理后,其与像素分割法测得结果没有明显差异。 | 牛冬瑜 黄慈航 仁乾龙珠 闵一桐 陈华鑫 K?llén H Heyden A ?str?m K | 2018 | 中外公路2018，38，3： | 3 |
| 8 | 抗P-21激活的磷酸化蛋白激酶5多克隆抗体的制备及其在牙胚细胞研究中的应用显示文摘目的克隆PAK5-N端基因并诱导其表达,进行多克隆抗体制备,为研究其在牙胚细胞中的生物学功能奠定基础。方法根据人全长PAK5cDNA序列,设计引物;利用PCR技术,以PAK5全长cDNA为模板扩增PAK5-N端基因,将扩增产物克隆至pGEX-4T-1载体中,经EcoRI/XhoI双酶切后进行重组质粒鉴定,DNA测序。以硫代半乳糖苷诱导其在大肠杆菌BL21中表达。利用GST融合蛋白纯化系统进行蛋白纯化,通过免疫家兔制备多克隆抗体,并在牙胚细胞中进行了初步研究。结果和结论成功克隆了PAK5-N端基因,在E.coli中表达了PAK5-NT,并纯化了GST融合蛋白,制备了PAK5特异性抗体。Westernblotting表明PAK5在牙胚细胞中过度表达,为其在口腔细胞中的生物学功能研究提供了依据。 | 安政雯 刘宏伟 贾志敏 李照峰 Staffan Strmblad 张宏权 | 2006 | 南方医科大学学报2006，26，6： | 3 |
| 9 | 中国的纺织品碳足迹显示文摘“碳足迹”的概念是用来描述完整的产品生产过程中温室气体的排放量的集合,以生产每千克织物排放多少克二氧化碳,作为二氧化碳的排放量。从纺织品的生命周期分析中可以看到,大约50%的二氧化碳排放量发生在增值链阶段(纤维的生产、制造、贸易和运输),50%则由日常使用产生。图1显示了纺织品从纤维到服装的生产过程中,主要的二氧化碳来源。 | Jürgen Strhle 谢峥 | 2012 | 印染2012，38，20： | 2 |
| 10 | THE INTEGRAL OF THE INVERSE FUNCTION OF φ FOR AN ANALYTICAL SOLUTION TO THE COMPRESSION OF A THIN WORKPIECE显示文摘An analytical solution of the unit pressure on a thin workpiece under compression has been obtained by using the inverse function of φ to the integral integral from 0 to x φ dx. Its result is basically the same as the prevailing numerical formula integral from 0 to x φdx=∑√1-Δx1. However, the new integral is simpler and more convenient to use. | Zhao, Dewen Northeast University of Technology, Shenyang 110006, China Fang, Youkang Institute fur Angewandte Mathematik Albert-Ludwigs Universitat, Hemann-Henter Str 10 7800 Freihurg.1. Br. BRD, Germany | 1993 | 中国有色金属学会会刊:英文版1993，3，1： | 2 |
| 11 | PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals显示文摘 | Maria Antonella Burza Carlo Pirazzi Cristina Maglio Kajsa Sj?holm Rosellina Margherita Mancina Per-Arne Svensson Peter Jacobson Martin Adiels Marco Giorgio Baroni Jan Borén Stefano Ginanni Corradini Tiziana Montalcini Lars Sj?str?m Lena Mariana Susann Car | 2012 | Digestive and Liver Disease2012，，12： | 2 |
| 12 | Functional studies of mesenchymal stem cells derived from adult human adipose tissue显示文摘 | Andrea Dicker Katarina Le Blanc Gaby ?str?m Vanessa van Harmelen Cecilia G?therstr?m Lennart Blomqvist Peter Arner Mikael Rydén | 2005 | Experimental Cell Research2005，，2： | 2 |
| 13 | Autophagosome-associated variant isoforms of cytosolic enzymes显示文摘 | Fengsrud M Raiborg C Berg TO Strmhaug PE Ueno T Erichsen ES Seglen PO | 2000 | Biochem J2000，352，3： | 1 |
| 14 | EGFR-tyrosine kinase inhibitor treatment beyond progression in long-term Caucasian responders to erlotinib in advanced non-small cell lung cancer: a case-control study of overall survival显示文摘 | M. Faehling R. Eckert T. Kamp S. Kuom U. Griese J. Str?ter G. Ott W. Spengler | 2013 | Lung Cancer2013，，： | 1 |
| 15 | Expression of platelet P-selectin and detection of soluble P-selectin, NPY and RANTES in patients with inflammatory bowel disease显示文摘 | J.P. F?gerstam P.A. Whiss M. Str?m R.G.G. Andersson | 2000 | Inflammation Research2000，，9： | 1 |
| 16 | Influence of humic substances on photolysis of divalent mercury in aqueous solution显示文摘 | Z. F. Xiao D. Str?mberg O. Lindqvist | 1995 | Water Air & Soil Pollution (-)1995，，1： | 1 |
| 17 | K‐ras mutations are correlated to lymph node metastasis and tumor stage, but not to the growth pattern of colon carcinoma显示文摘 | ABDULMANNAN VICTORIAHAHN‐STR?MBERG | 2012 | APMIS2012，，6： | 1 |
| 18 | Oral Pentasa in the treatment of active Crohn's disease:A meta-analysis of double-blind,placebo-controlled trials显示文摘 | Hanauer SB Strmberg U | 2004 | Clin Gastroenterol Hepatol2004，2，5： | 1 |
| 19 | X-stop versus decompressive surgery for lumbar neurogenic intermittent claudication:randomized controlled trial with 2-year follow-up显示文摘 | Str(o)mqvist BH Berg S Gerdhem P | 2013 | Spine2013，38，17： | 1 |
| 20 | Fractures in the proximal humerus:functional outcome and evaluation of 70 patients treated in hospital显示文摘 | Fjalestad T Str?ms?e K Blücher J | | 0，，05： | 1 |
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