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| 1 | Leukemia:研究鉴定出与34种AML白血病亚群相关联的基因突变显示文摘针对成年急性髓细胞白血病(acute myeloid leukemia,AML)患者的一项新的大型研究将80种癌症相关基因突变与5种AML亚型相关联。这5种AML亚型可通过特异性的染色体异常加以确定。在未来,这些发现可能有助指导基因突变测试和治疗决策。 | A-K Eisfeld K Mrózek J Kohlschmidt D Nicolet S Orwick C J Walker K W Kroll J S Blachly A J Carroll J E Kolitz B L Powell E S Wang R M Stone A de la Chapelle J C Byrd C D Bloomfield | 2017 | 现代生物医学进展2017，17，15： | 7 |
| 2 | Dyslipidemia management in primary prevention of cardiovascular disease:Current guidelines and strategies显示文摘Cardiovascular disease is the leading cause of death in the United States. In 2010, the Centers for Disease Control and Prevention estimated that $444 billion was spent on cardiovascular diseases alone, about $1 of every $6 spent on health care. As life expectancy continues to increase, this annual cost will also increase, making costeffective primary prevention of cardiovascular disease highly desirable. Because of its role in development of atherosclerosis and clinical events, dyslipidemia management is a high priority in cardiovascular prevention. Multiple major dyslipidemia guidelines have been published around the world recently, four of them by independent organizations in the United States alone. They share the goal of providing clinical guidance on optimal dyslipidemia management, but guidelines differ in their emphasis on pharmacotherapy, stratification of groups, emphasis on lifestyle modification, and use of a fixed target or percentage reduction in low density lipoprotein cholesterol. This review summarizes eight major guidelines for dyslipidemia management and considers the basis for their recommendations. Our primary aim is to enhance understanding of dyslipidemia management guidelines in patient care for primary prevention of future cardiovascular risk. | Aditya D Hendrani Tolulope Adesiyun Renato Quispe Steven R Jones Neil J Stone Roger S Blumenthal Seth S Martin | 2016 | World Journal of Cardiology2016，8，2： | 5 |
| 3 | Parallel processing with the perfect shuffle显示文摘 | Stone H S | 1971 | IEEE Transactions on Computers1971，20，2： | 1 |
| 4 | Spinal cord injury in children: long-term urodynamic and urological outcomes 显示文摘 | Generao S E Dall' era J P Stone A R | 2004 | J Urol2004，172，3： | 1 |
| 5 | Seasonal and diurnal body-mass fluctuations for two nonhoarding species ofparus in Sweden modeled using path analysis显示文摘 | Rintamaki P T Stone J R Lundberg S A | 2003 | Auk2003，120，3： | 1 |
| 6 | Cloning of DGAT2,a second mammalian diacylglycerol acyltransferase,and related family members 显示文摘 | Cases S Stone S J Zhou P | 2001 | J Biol Chem2001，276，38： | 1 |
| 7 | Berry anthocyanins as novel antioxidants in human health and disease prevention 显示文摘 | Zafra- Stone S Yasmin T Bagchi M | 2007 | Mol Nutr Food Res2007，51，6： | 1 |
| 8 | Effectiveness of barrier precautions and surveillance cultures to control transmission of multidrug-resistant organisms:a systematic review of the literature显示文摘 | Aboelela S W Saiman L Stone P | 2006 | Am J Infect Control2006，34，8： | 1 |
| 9 | Early Career out Cames of Graduate Employees: The Effect of Mentoring and in Graduations显示文摘 | Aryee S Wyatt T Stone R | 1996 | Journal of Management Studies1996，33，1： | 1 |
| 10 | Structure-function relations of heparin-mimetic sulphated xylan-oligosaccharides inhibition of Human Immunodeficiency Virus-1 infectivity in vitro显示文摘 | Stone A L Melton D J Lewis M S | 1998 | GlycoconjugateJournal1998，15，： | 1 |
| 11 | Extensive genomic conservation of catde micro satellite heterozygosity in sheep显示文摘 | Freking B A Kappes S M Leymaster K A Crawford A M Stone R T Beattie | 1997 | Animal Genetics1997，28，： | 1 |
| 12 | ARC1 is an E3 ubiquitin ligase and promotes the ubiquitination of proteins during the rejection of self-incompatible Brassica pollen 显示文摘 | Stone S L Anderson E M Mullen R T et cd | 2003 | Plant Cell2003，15，4： | 1 |
| 13 | Compensation of Nonlin- earities in Diode-Clamped Multilevel Converters显示文摘 | Minshull S Bingham C Stone D | 2010 | Industrial E- lectronics IEEE Transactions on2010，57，8： | 1 |
| 14 | Molecular differenc- es between hydrocarbon and fluorocarbon surfaetants at the COJ water interface 显示文摘 | Stone M T Da Rocha S R P Rossky P J | 2003 | Journal of Physics Chemistry2003，107，10： | 1 |
| 15 | Genetic diversity of Salmonella pathogenicity islands SPI-5 and SPI-6 in Salmonella Newport显示文摘 | Cao G Allard M Strain E Stones R Zhao S Brown E Meng J | 2014 | Foodborne Pathog Dis2014，11，10： | 1 |
| 16 | A dynamic range compression andthree-dimensional peptide fractionation analysisplatform expands proteome coverage and thediagnostic potential of whole saliva 显示文摘 | BANDHAKAVI S STONE M D ONSONGOG | 2009 | Journalof Proteome Research2009，8，55： | 1 |
| 17 | Recent developments in neuropsychological endophenotypes for schizophrenia: Development of the MATRICS battery, liability syndromes and the near future显示文摘Cognitive deficits are now recognized widely as core features of schizophrenia, and as major contributors to the clinical outcome of the disorder. They are also studied widely as 'endophenotypes', reflecting a growing consensus that schizophrenia is a broader, more multidimensional illness than the diagnostic criteria required for its formal diagnosis. This evolving view of cognition underlies its utilization in recent initiatives for intervention and assessment in schizophrenia. Two of these initiatives are reviewed in this paper. The first focuses on the development and validation of the MATRICS Cognitive Consensus Battery, a standardized battery of neuropsychological tests developed to assess the effectiveness of cognitive enhancing treatments in schizophrenia. A part of this effort includes the identification of performance-based, 'co-primary' measures of functional capacity that are related to cognition, and that are likely to show improvement at least partly as a function of improved cognition. The second initiative involves efforts to utilize neuropsychological deficits in the identification, validation and remediation of a liability syndrome for schizophrenia ('schizotaxia'). The discussion of this effort focuses on the development of a syndrome that is both measurable and meaningful clinically, and that may provide useful intervention targets. The utilization of cognition in both of these initiatives underscores its functional importance in the clinical outcome of schizophrenia. Moreover, it helps to illuminate indicators of liability for schizophrenia that might be amenable to remediation. | STONE William S HSI Xiaolu | 2011 | Chinese Science Bulletin2011，56，32： | 1 |
| 18 | Recognition and management of Tillaux fractures in adolescents显示文摘 | Koury S I Stone C K Harrell G | 1999 | J Pediatr Emerg Care1999，15，1： | 1 |
| 19 | Development of an Observational Measure of Healthcare Worker Hand-hygiene Behaviour:the Hand-hygiene Observation Tool (HHOT)显示文摘 | McAteer J Stone S Fuller C | 2008 | J Hosp Infect2008，68，3： | 1 |
| 20 | Platelet inhibition with cangrelor in patients undergoing PCI显示文摘 | Harrington RA Stone GW Menulty S | 2009 | N Engl J Med2009，361，24： | 1 |
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