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| 1 | Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population Utilizing Ultrasound and Liver Biopsy: A Prospective Study显示文摘 | Christopher D. Williams Joel Stengel Michael I. Asike Dawn M. Torres Janet Shaw Maricela Contreras Cristy L. Landt Stephen A. Harrison | 2011 | Gastroenterology2011，，1： | 20 |
| 2 | Dual-sugar tests of small intestinal permeability are poor predictors of bacterial infections and mortality in cirrhosis: a prospective study显示文摘AIM: To prospectively analyze the impact of increased intestinal permeability(IP) on mortality and the occurrence of infections in patients with cirrhosis.METHODS: IP was quantified using the lactulose/mannitol(L/M) test in 46 hospitalized patients with cirrhosis(25 Child-Pugh A/B, 21 Child-Pugh C) and in 16 healthy controls. Markers of inflammation [LPSbinding protein, Interleukin-6(IL-6)] and enterocyte death [intestinal fatty-acid binding protein(I-FABP)] were determined in serum using enzyme-linked immunosorbent assays. Patients were followed for one year and assessed for survival, liver transplantation, the necessity of hospitalization and the occurrence of bacterial infections. The primary endpoint of the study was defined as differences in survival between patients with pathological and without pathological lactulose/mannitol test.RESULTS: Thirty-nine(85%) patients with cirrhosis had a pathologically increased IP index(L/M ratio > 0.07) compared to 4(25%) healthy controls(P < 0.0001). The IP index correlated with the ChildPugh score(r = 0.484, P = 0.001) and with serum IL-6(r = 0.342, P = 0.02). Within one year, nineteen(41%) patients developed a total of 33 episodes of hospitalization with bacterial or fungal infections. Although patients who developed spontaneous bacterial peritonitis(SBP)(n = 7) had a higher IP index than patients who did not(0.27 vs 0.14, P = 0.018), the baseline IP index did not predict time to infection, infection-free survival or overall survival, neither when assessed as linear variable, as tertiles, nor dichotomized using an established cut-off. In contrast, model for end-stage liver disease score, Child-Pugh score, the presence of ascites, serum IL-6 and I-FABP were univariate predictors of infection-free survival.CONCLUSION: Although increased IP is a frequent phenomenon in advanced cirrhosis and may predispose to SBP, it failed to predict infection-free and overall survival in this prospective cohort study. | Anika Vogt Philipp A Reuken Sven Stengel Andreas Stallmach Tony Bruns | 2016 | World Journal of Gastroenterology2016，22，11： | 8 |
| 3 | Is infliximab safe to use while breastfeeding?显示文摘Inflammatory bowel disease (IBD) often affects women around the age of conception and pregnancy. Most drugs used to treat IBD are safe in pregnancy, but physicians must consider the clinical implications of certain treatment regimens in young, fertile females. We report an informative case of a pregnant patient with IBD who underwent treatment with infliximab during her pregnancy and while nursing her infant. Serum and breast milk infliximab levels were monitored throughout this time period. This case report suggests that targeted monoclonal antibodies and other biologic agents can be used with caution in pregnant and breastfeeding patients. | Joel Z Stengel Hays L ArnoldJ | 2008 | World Journal of Gastroenterology2008，14，19： | 6 |
| 4 | Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population Utilizing Ultrasound and Liver Biopsy: A Prospective Study显示文摘 | Christopher D. Williams Joel Stengel Michael I. Asike Dawn M. Torres Janet Shaw Maricela Contreras Cristy L. Landt Stephen A. Harrison | 2011 | Gastroenterology2011，，1： | 5 |
| 5 | Preprotein Import into Chloroplasts via the Toc and Tic Complexes Is Regulated by Redox Signals in Pisum sativum显示文摘原子编码 preproteins 的进口是必要的维持叶绿体功能。越过叶绿体信封的大多数先锋蛋白质的识别和转移被二插入膜的蛋白质建筑群,外部的叶绿体的 translocons 和内部信封便于(Toc 和 Tic 建筑群,分别地) 。几个信号被调用了调整 preproteins 的进口。在我们的学习,我们对基于氧化还原作用的进口感兴趣规定由二个信号调停了:规定基于 thiols 并且在新陈代谢的 NADP+/NADPH 比率上。我们寻求了鉴别参予这些的规定的蛋白质搬运小径并且描绘其进口是氧化还原作用依赖者的 preprotein 亚群。我们的结果提供在 Toc 受体和 Toc translocation 隧道的二硫化物桥的形成和减小在所有测试 preproteins 的进口产量上有强烈影响的证据为 translocation 取决于 Toc 建筑群。而且,新陈代谢的 NADP+/NADPH 比率影响 Tic 建筑群,而且大多数,然而并非所有的进口效率的不仅作文,测试的 preproteins。因此,几 Tic subcomplexes 看起来参予不同 preprotein 亚群的 translocation,并且这些建筑群的氧化还原作用活跃的部件多半在调整运输起一个作用。 | Anna Stengel | 2009 | Molecular Plant2009，2，6： | 4 |
| 6 | Localization of nesfatin-1 neurons in the mouse brain and functional implication显示文摘 | Miriam Goebel-Stengel Lixin Wang Andreas Stengel Yvette Taché | 2011 | Brain Research2011，，： | 2 |
| 7 | Retrograde fixation of distal fern oral fractures:Results using a new nail system显示文摘 | Seifert J Stengel D Mattes G | 2003 | J Orthop Trauma2003，17，6： | 1 |
| 8 | Adenovirus- mediated gene transfer of human platelet-activting factor-acetylhydrolase prevents injury-induced neointima formation and reduces spontaneous atherosclerosis in apolipoprotein E-deficient mice显示文摘 | Quarck R De Geest B Stengel D | 2001 | Circulation2001，103，： | 1 |
| 9 | Primary total hip arthroplasty versus hemiarthmplasty for displaced int- racapsular hip fractures in older patients:systematic rev- iew显示文摘 | Hopley C Stengel D Ekkemkamp A | 2010 | BMJ2010，340，： | 1 |
| 10 | Cadmium in the invertebrate fauna of an unpolluted forest in Switzerland 显示文摘 | Knutti R Bucher P Stengel M | 1988 | En- viron Toxicol Ser1988，2，： | 1 |
| 11 | Effect of exercise and Cim- icifuga racemosa ( CR BNO 1055 ) on bone mineral density, 10-year coro- nary heart disease risk, and menopausal complaints:the randomized con- trolled Training and Cimicifuga racemosa Erlangen (TRACE) study 显示文摘 | Bebenek M Kemmler W von Stengel S | 2010 | Menopause2010，17，4： | 1 |
| 12 | Nesfatin-1 immu-noreactivity in rat brain and spinal cord autonomic nuclei显示文摘 | Goebel M Stengel A Wang L | 2009 | Neurosci Lett2009，452，3： | 1 |
| 13 | Exercise and osteoporosis-related fractures:perspectives and recommendations of the sports and exercise scientist显示文摘 | Kemmler W von Stengel S | | 0，，01： | 1 |
| 14 | Corticotropin-relcasing factor signaling and visceral response to stress 显示文摘 | Stengel A Tache Y | 2010 | Exp Biol Med2010，235，10： | 1 |
| 15 | Effects of mutations and glycosylations on STS activity: a site-directed mutagenesis study显示文摘 | Stengel C Newman S P Day J M Tutill H J Reed M J Purohit A | 2008 | Molecular and Cellular Endocrinology2008，283，1： | 1 |
| 16 | The use of image processing in assessing conchocelis growth and conchospore pro-duction in Porphyra linearis显示文摘 | Varela-Alvarez E Stengel D B Guiry M D | 2004 | Phycologia2004，43，3： | 1 |
| 17 | Flight control design using non-linear inverse dynamics显示文摘 | Lane S H Stengel R F | 1988 | Automatica1988，24，4： | 1 |
| 18 | Robust nonlinear control of a hypersonic aircraft显示文摘 | Wang Q Stengel R F | 2000 | Journal of Guidance Control and Dynamics2000，23，4： | 1 |
| 19 | Power training is more effective than strength training for maintaining bone mineral density in postmenopausal women显示文摘 | Stengel S V Kemmler W Pintag R | 2005 | J Appl Physio2005，99，1： | 1 |
| 20 | Robust nonlinear control of a hypersonic aircraft 显示文摘 | WANG Q STENGEL R F | 2000 | Journal of Guidance Control and Dynamics2000，23，4： | 1 |
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