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| 1 | Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。 | Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim | 2015 | Cell Research2015，25，6： | 20 |
| 2 | Promotion of Pt/γ-Al2O3 by Ce for preferential oxidation of CO in H2显示文摘 | Son I H Lane A M | 2001 | Catalysis Letters2001，176，34： | 2 |
| 3 | Improving the performance of time-constrained workflow processing显示文摘 | Son J H Kim M H | 2001 | The Journal of System and Software2001，58，3： | 1 |
| 4 | Antibiotic resistance and plasmid profile of Aeromonas hydrophilia isolates from cultured fish 显示文摘 | Son R Rusul G Sahilah A M | 1997 | Letters of Applied Microbiology1997，，24： | 1 |
| 5 | Energy gaps in gra- phene nanoribbons 显示文摘 | SON Y W COHEN M L LOUIE S G | 2006 | Physical Review Letters2006，97，21： | 1 |
| 6 | Morphology devel- opment and crystallization behavior of poly ( ethylene tereph- thalate)/poly ( trimethylene terephthalate ) blends 显示文摘 | KIM G S SON J M LEE J K | 2010 | Eur Polym J2010，46，8： | 1 |
| 7 | Researchers' Perspectives on Sup- ply Chain Risk Management 显示文摘 | Sodhi M S Son B G Tang C S | 2012 | Production and Operations Man- agement2012，21，1： | 1 |
| 8 | Surface plasmon enhanced photoconductance and single electron effects in mesoporous titania nanofibers loaded with gold nanoparticles显示文摘 | SON M IM J WANG K | 2010 | Appl Phys Lett2010，96，02： | 1 |
| 9 | Lithological and Mineralogi- cal Survey of the Oyu Tolgoi Region, Southeastern Gobi, Mongolia Using ASTER Reflectance and Emissivity data 显示文摘 | Son Y S Kang M K Yoon W J | 2014 | International Journal of Applied Earth Observation and Geoin- formation2014，26，： | 1 |
| 10 | Extracting the workflow critical path from the extended well formed workflow schema显示文摘 | SON J H KIM J S KIM M H | 2005 | Journal of Computer and System Sciences2005，70，1： | 1 |
| 11 | Vibratory stress relief:A fundamental study of its effectiveness显示文摘 | M offat D G | 1980 | Journal of Engineering Materials and Technology1980，，4： | 1 |
| 12 | Growth of highly oriented TiO2 thin films on InP(100) substrates by metalorganic chemical vapor deposition显示文摘 | Kim E K Son M H | 1997 | Journal of Crystal Growth1997，170，4： | 1 |
| 13 | Impact of laparoscopic surgery on the long-term outcomes for patients with rectal cancer显示文摘 | Kim J G Heo Y J son G M | 2009 | ANZ J Surg2009，79，11： | 1 |
| 14 | Anticancer activity of HS-527, a novel inhibitor targeting PI3-kinase in human pancreatic cancer cells显示文摘 | Ryu Y L Jung K H Son M K | 2014 | Cancer Lett2014，353，1： | 1 |
| 15 | Rapid simultaneous determina- tion of amines and organic acids in citrus using high-performance liquid chromatography显示文摘 | UCKOO R M JAYAPRAKASHA G K NEL- SON S D | 2011 | Ta- lanta2011，83，3： | 1 |
| 16 | NAD(P)H oxidase participates in the signaling events in high glucose-induced proliferation of vascular smooth muscle cells显示文摘 | SON S M KIM Y K | 2003 | Life Sci2003，72，24： | 1 |
| 17 | Antioxidant and synergistic effect of sesame oil cake extract treated fromβ - glucosidase显示文摘 | SON J Y KANG D W SHIN G M | 2001 | Korean J Food Nutr2001，14，6： | 1 |
| 18 | Improving the performance of time-constrained workflow processing显示文摘 | SON J KIM M | 2001 | The Journal of Systems and Software2001，58，1： | 1 |
| 19 | Thymosin β10 inhibits an- giogenesis and tumor growth by interfering with Ras function 显示文摘 | Lee S H Son M J Oh S H | 2005 | Cancer Res2005，65，： | 1 |
| 20 | Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection 显示文摘 | Petrovas C Chaon B Amhrozak DR Price DA Melen- horst JJ Hill BJ Geldmacher C Casazza JP Chatto- padhyay PK Roederer M Douek DC Mueller YM Jacob- son JM Kulkarni V Felber BK Pavlakis GN Katsikis PD Koup RA | 2009 | J Immunol2009，183，2： | 1 |
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