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| 1 | Drain amylase value as an early predictor of pancreatic fistula after cephalic duodenopancreatectomy显示文摘AIM:To determine predictors of clinically relevant pancreatic fistulas(CRPF)by measuring drain fluid amylase(DFA)in the early postoperative period.METHODS:This prospective clinical study included382 patients with periampullary tumors that were surgically resected at our department between March 2005and October 2012.A cephalic duodenopancreatectomy (DP)was performed on all patients.Two closed suction drains were placed at the end of the surgery.The highest postoperative DFA value was recorded and analyzed during the first three postoperative days and on subsequent days if the drains were kept longer.Pancreatic fistula(PF)was classified according to the International Study Group of Pancreatic Fistula(ISGPF)criteria.Postoperative complications were defined according to the Dindo-Clavien classification.All data were statistically analyzed.The optimal thresholds of DFA levels on the first,second and third postoperative days were estimated by constructing receiver operating curves,generated by calculating the sensitivities and specificities of the DFA levels.The DFA level limits were used to differentiate between the group without PF and the groups with biochemical pancreatic fistula(BPF)and CRPF.RESULTS:Pylorus-preserving duodenopancreatectomy was performed on 289(75.6%)patients,while the remaining patients underwent a classic Whipple procedure(CW).The total incidence of PF was 37.7%(grade A22.8%,grade B 11.0%and grade C 3.9%).Soft pancreatic texture(SPT)was present in 58.3%of patients who developed PF.Mortality was 4.2%.The median DFA value on the first postoperative day(DFA1)in patients who developed PF was 4520 U/L(range 350-99000 U/L)for grade A fistula(BPF)with a SPT and a diameter of the main pancreatic duct(MPD)of≤3 mm.For grade B/C(CRPF),the median DFA1 value was 8501 U/L(range377-92060 U/L)with a SPT and MPD of≤3 mm.These values were significantly higher when compared to the patients who did not have PF(122;range 5-37875 U/L).The upper limit of DFA values for the first 3 postoperative days in the examined stages of PF were:DFA1 1200U/L for the BPF and CRPF;DFA3 350 U/L for BPF and DFA3 800 U/L for CRPF.The determined values were highly significant and demonstrated a reliable diagnostic test for both BPF and CRPF.CONCLUSION:DFA1≥1200 U/L is an important predictive factor for PF of any degree.The trend of DFA3(decrease of<50%)compared to DFA1 is a significant factor in the differentiation of CRPF from transient BPF. | Vladimir D Dugalic Djordje M Knezevic Vladan N Obradovic Miroslava G Gojnic-Dugalic Slavko V Matic Aleksandra R Pavlovic-Markovic Predrag D Dugalic Srbislav M Knezevic | 2014 | World Journal of Gastroenterology2014，20，26： | 7 |
| 2 | Primary retroperitoneal mucinous cystadenoma:A case report显示文摘Primary retroperitoneal mucinous cystic tumors are extremely rare.These tumors can be classified as a primary retroperitoneal mucinous cystadenoma with or without borderline malignancy or primary retroperitoneal mucinous cystadenocarcinoma.The most common of these is primary retroperitoneal mucinous cystadenoma,which almost always occurs in female patients;only ten cases have been reported in males.The most common clinical findings for this tumor type include nonspecific abdominal pain and a palpable abdominal mass.A definitive diagnosis is usually obtained from histopathology after surgical excision.Here,we report the case of a 60-year-old female patient who complained of abdominal pain that had been present for 3 mo and presented with a palpable abdominal mass.Multidetector computed tomography scanning revealed a large,unilocular cystic mass in the left retroperitoneal space.Surgical intervention was performed and the tumor was completely removed.Histopathologic examination confirmed that the tumor was a primary retroperitoneal mucinous cystadenoma.Two years after surgery,the patient remains disease free. | Srbislav Knezevic Igor Ignjatovic Snezana Lukic Slavko Matic Vladimir Dugalic Djordje Knezevic Marjan Micev Sanja Dragasevic | 2015 | World Journal of Gastroenterology2015，21，17： | 3 |
| 3 | Experimental Investigation of Pyrolysis Process of Woody Biomass Mixture显示文摘This paper describes an experimental investigation of pyrolysis of woody biomass mixture. The mixture consists of oak, beech, fir, cherry, walnut and linden wood chips with equal mass fractions. During the experiment, the sample mass inside the reactor was 10 g with a particle diameter of 5-10 mm. The sample in the reactor was heated in the temperature range of 24-650oC. Average sample heating rates in the reactor were 21, 30 and 54 oC/min. The sample mass before, during and after pyrolysis was determined using a digital scale. Experimental results of the sample mass change indicate that the highest yield of pyrolytic gas was achieved at the temperature slightly above 650oC and ranged from 77 to 85%, while char yield ranged from 15 to 23%. Heating rate has significant influence on the pyrolytic gas and char yields. It was determined that higher pyrolysis temperatures and heating rates induce higher yields of pyrolytic gas, while the char mass reduces. Condensation of pyrolytic gas at the end of the pyrolysis process at 650oC produced 2.4-2.72 g of liquid phase. The results obtained represent a starting basis for determining material and heat balance of pyrolysis process as well as woody biomass pyrolysis equipment. | Tijana R.Kosanic Mirjana B.Ceranic Slavko N.Duric Vojin R.Grkovic Milan M.Milotic Sasa D.Brankov | 2014 | Journal of Thermal Science2014，23，3： | 2 |
| 4 | Perigastric extraskeletal Ewing's sarcoma: A case report显示文摘Ewing's sarcoma (ES) is a neoplasm of undifferentiated small round cells, which occurs in the bones and deep soft tissues of children and adolescents. We present a rare case of a 44-year-old woman with gastric ES presenting with epigastric pain and weight loss. Ultrasound and computed tomography scans indicated a solid/cystic mass in the pancreatic tail. At laparotomy, the tumor was found attached to the posterior surface of the stomach, completely free from the pancreas, with no lymphadenopathy or local metastases. The polynodal, partly pseudocystic, dark-red soft tumor was excised. Histopathology revealed an anaplastic small-round-cell tumor with strong membranous CD99 immunoexpression. Additionally, there was patchy immunostaining for S-100 protein, vimentin, protein gene product (PGP) 9.5 and neuron-specifi c enolase, and weak focal CD117 cytoplasmic immunoreactivity. The patient had no adjuvant chemotherapy; her postoperative recovery was uneventful, and she remains symptom-free, and without any sign of recurrence at 20 mo. To the best of our knowledge, this is only the third ever case of gastric ES. | Radoje B Colovic Nikica M Grubor Marjan T Micev Slavko V Matic Henry Dushan Edward Atkinson Stojan M Latincic | 2009 | World Journal of Gastroenterology2009，15，2： | 2 |
| 5 | Color Doppler sonography and angioscintigraphy in hepatic Hodgkin's lymphoma显示文摘AIM:To estimate the characteristics of Color Doppler findings and the results of hepatic radionuclide angiography (HRA) in secondary Hodgkin's hepatic lymphoma.METHODS:The research included patients with a diagnosis of Hodgkin's lymphoma with metastatic focal lesions in the liver and controls.Morphologic characteristics of focal liver lesions and hemodynamic parameters were examined by pulsed and Color Doppler in the portal,hepatic and splenic veins were examined.Hepatic perfusion index (HPI) estimated by HRA was calculated.RESULTS:In the majority of patients,hepatomegaly was observed.Lesions were mostly hypoechoic and mixed,solitary or multiple.Some of the patients presented with dilated splenic veins and hepatofugal blood flow.A pulse wave was registered in the centre and at the margins of lymphoma.The average velocity of the pulse wave was higher at the margins (P>0.05).A continuous venous wave was found only at the margins of lymphoma.There was no linear correlation between lymphoma size and velocity of pulse and continuous wave (r=390,P<0.01).HPI was significantly lower in patients with lymphomas than in controls (P<0.05),pointing out increased arterial perfusion in comparison to portal perfusion.CONCLUSION:Color Doppler ultrasonography is a sensitive method for the detection of neovascularization in Hodgkin's hepatic lymphoma and estimation of its intensity.Hepatic radionuclide angiography can additionally help in the assesment of vascularisation of liver lesions. | Mirjana V Stojkovi Vera M Artiko Irena B Radoman Slavko J Knezevi Snezana M Luki Mirko D Kerkez Nebojsa S Leki Andrija A Anti Marinko M Zuvela Vitomir I Rankovi Milorad N Petrovi Dragana P obi Vladimir B Obradovi | 2009 | World Journal of Gastroenterology2009，15，26： | 2 |
| 6 | 低温烧结制度对ZnO-Bi2O3基压敏陶瓷显微结构与电性能的影响显示文摘采用传统电子陶瓷的制备工艺,制备了相同Bi_2O_3含量、Sb_2O_3/Bi_2O_3比分别为0.25、0.50的ZnO-Bi_2O_3基压敏陶瓷,研究在800℃-950℃区间内一步烧结与两步烧结制度对陶瓷的显微结构与电性能的影响。显微结构分析表明,烧结过程中足够的Bi_2O_3液相有利于烧结,而且能够促进晶粒内含反演边界(Inversion Boundary)的ZnO晶粒的长大。烧成的样品具有发育良好的显微结构:高的致密度、均匀的含Bi第二相分布以及粒径,而且电性能良好:压敏电压327-670 V/mm,非线性系数20-31,漏电流低于0.5μA。Sb_2O_3含量较高的样品,晶粒尺寸较小,压敏电压和非线性系数较大,漏电流较小。研究还发现,ZnO晶粒尺寸以受两步烧结制度里占主要的烧结过程的影响为主。研究结果表明:与传统的1000℃以上烧结相比,合理的配方是保证在800℃-950℃区间内烧结获得综合性能良好的压敏陶瓷样品的关键。 | 程丽红 Slavko Bernik Matejka Podlogar 郑嘹赢 李国荣 | 2017 | 陶瓷学报2017，38，5： | 2 |
| 7 | Regulation of the mesenchymal stem cell fate by interleukin-17: Implications in osteogenic differentiation显示文摘Bone regeneration is a tightly regulated process that ensures proper repair and functionality after injury.The delicate balance between bone formation and resorption is governed by cytokines and signaling molecules released during the inflammatory response.Interleukin(IL)-17A,produced in the early phase of inflammation,influences the fate of osteoprogenitors.Due to their inherent capacity to differentiate into osteoblasts,mesenchymal stem/stromal cells(MSCs)contribute to bone healing and regeneration.This review presents an overview of IL-17A signaling and the leading cellular and molecular mechanisms by which it regulates the osteogenic differentiation of MSCs.The main findings demonstrating IL-17A’s influence on osteoblastogenesis are described.To this end,divergent information exists about the capacity of IL-17A to regulate MSCs’osteogenic fate,depending on the tissue context and target cell type,along with contradictory findings in the same cell types.Therefore,we summarize the data showing both the pro-osteogenic and anti-osteogenic roles of IL-17,which may help in the understanding of IL-17A function in bone repair and regeneration. | Jelena Krstić Slavko Mojsilović Sonja S Mojsilović Juan F Santibanez | 2021 | World Journal of Stem Cells2021，13，11： | 2 |
| 8 | Two synchronous somatostatinomas of the duodenum and pancreatic head in one patient显示文摘Somatostatinomas are extremely rare neuroendocrine tumors of the gastrointestinal tract,f irst described in the pancreas in 1977 and in the duodenum in 1979.They may be functional and cause somatostatinoma or inhibi-tory syndrome,but more frequently are non-functioning pancreatic endocrine tumors that produce somatostatin alone.They are usually single,malignant,large lesions,frequently associated with metastases,and generally with poor prognosis.We present the unique case of a 57-year-old woman with two synchronous non-function-ing somatostatinomas,one solid duodenal lesion and one cystic lesion within the head of the pancreas,that were successfully resected with a pylorus-preserving Whipple's procedure.No secondaries were found in the liver,or in any of the removed regional lymph nodes.The patient had an uneventful recovery,and remains well and symptom-free at 18 mo postoperatively.This is an extremely rare case of a patient with two synchro-nous somatostatinomas of the duodenum and the pancreas.The condition is discussed with reference to the literature. | Radoje B olovi Slavko V Mati Marjan T Micev Nikica M Grubor Henry Dushan Atkinson Stojan M Latini | 2009 | World Journal of Gastroenterology2009，15，46： | 1 |
| 9 | Abdominal neurenteric cyst显示文摘Neurenteric cysts are extremely rare congenital anomalies,often presenting in the first 5 years of life,and are caused by an incomplete separation of the notochord from the foregut during the third week of embryogenesis. They are frequently accompanied with spinal or gastrointestinal abnormalities,but the latter may be absent in adults. Although usually located in the thorax,neurenteric cysts may be found along the entire spine. We present a 24-year-old woman admitted for epigastric pain,nausea,vomiting,low grade fever and leucocytosis. She underwent cystgastrostomy for a loculated cyst of the distal pancreas at the age of 4 years,which recurred when she was at the age of 11 years. Ultrasound and computer tomograghy(CT) scan revealed a 16 cm × 15 cm cystic mass in the body and tail of pancreas,with a 6-7 mm thickened wall. Laboratory data and chest X-ray were normal and spinal radiographs did not show any structural abnormalities. The patient underwent a complete cyst excision,and after an uneventful recovery,remained symptom-free without recurrence during the 5-year follow-up. The cyst was found to contain 1200 mL of pale viscous fluid. It was covered by a primitive single-layered cuboidal epithelium,along with specialized antral glandular parenchyma and hypoplastic primitive gastric mucosa. Focal glandular groups resemblingthose of the body of the stomach were also seen. In addition,ciliary respiratory epithelium,foci of squamous metaplasia and mucinous glands were present. The wall of the cyst contained a muscular layer,neuroglial tissue with plexogenic nerve fascicles,Paccini corpuscle-like structures,hyperplastic neuroganglionar elements and occasional psammomatous bodies,as well as fibroblast-like areas of surrounding stroma. Cartilagenous tissue was not found in any part of the cyst. Immunohistochemistry confirmed the presence of neurogenic elements marked by S-100,GFAP,NF and NSE. The gastric epithelium showed mostly CK7 and EMA immunoexpression,and the respiratory epithelium revealed a CK8 and CK18 immunoprofile without CK 10/13 positive elements,though neither CEA or AFP positive cells were found. To our knowledge,this is the first reported case of an abdominally located neurenteric cyst with no associated spinal anomalies. | Radoje olovi Marjan Micev Miodrag Jovanovi Slavko Mati Nikica Grubor Henry Dushan E Atkinson | 2008 | World Journal of Gastroenterology2008，14，23： | 1 |
| 10 | Gel-combustion synthesis of Ni-MoO3 mixtures and their reduction to Ni-Mo alloys显示文摘 | Slavko M Biljanan T Divna M | 2008 | MaterialsChemistry and Physics2008，112，5： | 1 |
| 11 | A study of caffeine binding to human serum albumin显示文摘 | ANITA K MARINA K SLAVKO P GRETA P | 2005 | Croat Chem Acta2005，78，1： | 1 |
| 12 | Wear mechanisms of cutting tools in high-speed cutting processes显示文摘 | Slavko Dolinsek Borivoj Sustarsic Janez Kopac | 2001 | Wear2001，250，3： | 1 |
| 13 | A Theoretical Model Applying Fuzzy Logic Theory for Evaluating Personnel in Project Management显示文摘 | Darko Galinec Slavko Vidovic | 2006 | Journal of Behavioral and Applied Management2006，，： | 1 |
| 14 | Risk Factor Analysis and Diagnoses of Coronary Heart Disease in Patients with Hypercholesterolemia from Croatian Zagorje County显示文摘 | Ksenija Pe?ek Damir Bukovi? Tomislav Pe?ek Slavko Ore?kovi? Darko Milinovi? Marko Rukavina Mato Pavi? Marija Zlojtro | 2008 | Collegium Antropologicum2008，，2： | 1 |
| 15 | New me- dia, new research challenges: an introduction显示文摘 | PETER GOLDING SLAVKO SPLICHAL | 2013 | Javnost-the public2013，20，2： | 1 |
| 16 | Wear Mechanisms of cutting tools in high-speed cutting processes显示文摘 | Slavko Dolinsek Borivoj Sustarsic Janez Kopac | 2001 | Wear2001，250，： | 1 |
| 17 | Influence of quenching process parameters on residual stresses in steel显示文摘 | Janez Grum Slavko Bo?i? Martin Zupan?i? | 2001 | Journal of Materials Processing Tech2001，，1： | 1 |
| 18 | Gel-combustion synthesis of Ni-Mo O3 mixtures and their reduction to Ni-Mo alloys显示文摘 | Slavko M Biljanan T Divna M | 2008 | Materials Chemistry and Physics2008，112，： | 1 |
| 19 | Acoustic emission signals for tool wear identification显示文摘 | Dolinsek Slavko Kopac Janez | 1999 | Wear1999，，： | 1 |
| 20 | Plants and human health in the twenty-first century显示文摘 | Ilya Raskin David M. Ribnicky Slavko Komarnytsky Nebojsa Ilic Alexander Poulev Nikolai Borisjuk Anita Brinker Diego A. Moreno Christophe Ripoll Nir Yakoby Joseph M. O'Neal Teresa Cornwell Ira Pastor Bertold Fridlender | 2002 | Trends in Biotechnology2002，，12： | 1 |
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