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| 1 | Systematic review of prognostic importance of extramuralvenous invasion in rectal cancer显示文摘AIM: To systematically review the survival outcomes relating to extramural venous invasion in rectal cancer.METHODS: A systematic review was conducted using PRISMA guidelines. An electronic search was carried out using MEDLINE, EMBASE, CINAHL, Cochrane library databases, Google scholar and Pub Med until October 2014. Search terms were used in combination to yield articles on extramural venous invasion in rectal cancer. Outcome measures included prevalence and 5-year survival rates. These were graphically displayed using Forest plots. Statistical analysis of the data was carried out.RESULTS: Fourteen studies reported the prevalence of extramural venous invasion(EMVI) positive patients. Prevalence ranged from 9%-61%. The pooled prevalence of EMVI positivity was 26% [Random effects: Event rate 0.26(0.18, 0.36)]. Most studies showed that EMVI related to worse oncological outcomes. The pooled overall survival was 39.5% [Random effects: Event rate 0.395(0.29, 0.51)].CONCLUSION: Historically, there has been huge variation in the prevalence of EMVI through inconsistent reporting. However the presence of EMVI clearly leads to worse survival outcomes. As detection rates become more consistent, EMVI may be considered as part of risk-stratification in rectal cancer. Standardised histopathological definitions and the use of magnetic resonance imaging to identify EMVI will improve detection rates in the future. | Manish Chand Muhammed RS Siddiqui Ian Swift Gina Brown | 2016 | World Journal of Gastroenterology2016，22，4： | 15 |
| 2 | Nitrogen in Relation to Photosynthetic Capacity and Accumulation of Osmoprotectant and Nutrients in Brassica Genotypes Grown Under Salt Stress显示文摘Different strategies of the application of nutrients are required to overcome the adverse effects of mustard (Brassica juncea L.) in response to NaCl stress. The objective of the present study was to determine if different added levels of nitrogen (N) in growth medium could alleviate the adverse effects of salt stress on photosynthetic capacity and accumulation of osmoprotectants and nutrients. 14 days mustard seedlings of salt-sensitive (cv. Chuutki) and salt-tolerant (cv. Radha) genotypes were fed with: (i) 0 mmol L-1 NaCl + 0 mg N kg-1 sand (control), (ii) 90 mmol L-1 NaCl + 30 mg N kg-1 sand, (iii) 90 mmol L-1 NaCl + 60 mg N kg-1 sand, (iv) 90 mmol L-1 NaCl + 90 mg N kg-1 sand and (v) 90 mmol L-1 NaCl + 120 mg N kg-1 sand. Under the condition of salinity stress, N application caused a significant ameliorative effect on both genotypes with respect to growth attributes [fresh weight (FW) and dry weight (DW)] and physio-biochemical parameters [percent water content (WC), net photosynthetic rate (PN), stomatal conductance (gs), total chlorophyll (Chl), carbonic anhydrase (CA) activity and malondialdehyde (MDA), nitrogen (N), potassium (K) and sodium (Na) contents, and K/Na ratio] and yield attributes (number of pods/plant, seeds/pod and seed yield/plant). The salt-tolerant genotype exhibited maximum value for growth, physio-biochemical and yield attributes at 60 mg N kg-1 sand than that of salt-sensitive genotype. These results suggest that application of N may ameliorate most of the attributes and prove to be a physiological remedy to increase the tolerance against the ill effects of salt stress in Brassicas. | Manzer H Siddiqui Firoz Mohammad M Nasir Khan Mohamed H Al-Whaibi Ali H A Bahkali | 2010 | Agricultural Sciences in China2010，9，5： | 14 |
| 3 | 医学专业本科留学生教育限制性因素调查分析及对策建议显示文摘目的对留学生医学教育发展的限制性因素进行调查。方法2011至2013年对重庆医科大学350名在校留学生进行现场问卷调查,回收有效答卷339份。结果调查发现,仅有33.0%(112人)的学生认为授课教师英语表达较为顺畅,70.2%(238人)的学生有增加中文课的需求。另外,被调查学生中认为理论知识教育不够以及动手机会太少的分别占69.6%(236人)和63.1%(214人)。92.3%(313人)的学生来自东南亚地区等发展中国家。86.1%(292人)的学生认为学校对其管理不足。结论通过此次调查发现。影响留学生医学教育发展的因素主要有语言水平与需求不平衡、专业知识教育及实践不足、生源问题以及日常管理中的困难等。 | 谭继翔 张丹 赵林 刘景仑 王栋 Islam Mohammed Aftab Chouhan Dawood Siddiqui | 2016 | 中华医学教育探索杂志2016，15，2： | 14 |
| 4 | Enteral stents for the management of malignant colorectal obstruction显示文摘Colorectal cancer(CRC) is the 3rd most common cancer in the United States with more than 10000 new cases diagnosed annually. Approximately 20% of patients with CRC will have distant metastasis at time of diagnosis, making them poor candidates for primary surgical resection. Similarly, 8%-25% of patients with CRC will present with bowel obstruction and will require palliative therapy. Emergent surgical decompression has a high mortality and morbidity, and often leads to a colostomy which impairs the patient's quality of life. In the last decade, there has been an increasing use of colonic stents for palliative therapy to relieve malignant colonic obstruction. Colonic stents have been shown to be effective and safe to treat obstruction from CRC, and are now the therapy of choice in this scenario. In the setting of an acute bowel obstruction in patients with potentially resectable colon cancer, stents may beused to delay surgery and thus allow for decompression, adequate bowel preparation, and optimization of the patient's condition for curative surgical intervention. An overall complication rate(major and minor) of up to 25% has been associated with the procedure. Long term failure of stents may result from stent migration and tumor ingrowth. In the majority of cases, repeat stenting or surgical intervention can successfully overcome these adverse effects. | Jeremy Kaplan Anna Strongin Douglas G Adler Ali A Siddiqui | 2014 | World Journal of Gastroenterology2014，20，37： | 13 |
| 5 | 新生儿坏死性小肠结肠炎发病机制的研究进展显示文摘新生儿坏死性小肠结肠炎(NEC),是新生儿重症监护病房常见的危重胃肠道炎症性疾病,严重危及患儿生命。目前认为导致NEC的主要危险因素包括早产、肠道菌群失调、炎症反应、输注血液制品及喂养不当等,但是该病的具体发病机制迄今尚未明确。笔者拟就目前有关NEC发病机制的最新研究进行综述。 | 马娜 Mohd Jaish Siddiqui 夏斌 | 2020 | 中华妇幼临床医学杂志(电子版)2020，16，6： | 10 |
| 6 | Treatment of hemorrhoids: A survey of surgical practice in Australia and New Zealand显示文摘BACKGROUND Hemorrhoidal disease is the most common anorectal disorder.Hemorrhoids can be classified as external or internal,according to their relation to the dentate line.External hemorrhoids originate below the dentate line and are managed conservatively unless the patient cannot keep the perianal region clean,or they cause significant discomfort.Internal hemorrhoids originate above the dentate line and can be managed according to the graded degree of prolapse,as described by Goligher.Generally,low-grade internal hemorrhoids are effectively treated conservatively,by non-operative measures,while high-grade internal hemorrhoids warrant procedural intervention.AIM To determine the application of clinical practice guidelines for the current management of hemorrhoids and colorectal surgeon consensus in Australia and New Zealand.METHODS An online survey was distributed to 206 colorectal surgeons in Australia and New Zealand using 17 guideline-based hypothetical clinical scenarios.RESULTS There were 82 respondents(40%)to 17 guideline-based scenarios.Nine(53%)reached consensus,of which only 1(6%)disagreed with the guidelines.This was based on low quality evidence for the management of acutely thrombosed external hemorrhoids.There were 8 scenarios which showed community equipoise(47%)and they were equally divided for agreeing or disagreeing with the guidelines.These topics were based on low and moderate levels of evidence.They included the initial management of grade I internal hemorrhoids,grade III internal hemorrhoids when initial management had failed and the patient had recognised risks factors for septic complications;and finally,the decision-making when considering patient preferences,including a prompt return to work,or minimal post-operative pain.CONCLUSION Although there are areas of consensus in the management of hemorrhoids,there are many areas of community equipoise which would benefit from further research. | George E Fowler Javariah Siddiqui Assad Zahid Christopher John Young | 2019 | World Journal of Clinical Cases2019，7，22： | 8 |
| 7 | Vegetation-environment relationships in the forests of Chitral district Hindukush range of Pakistan显示文摘We investigated the composition of plant communities to quantify their relationships with environmental parameters in the Chitral Hindukush range of Pakistan. We sampled tree vegetation using the Point Centered Quarter (PCQ) method while understory vegetation was sampled in 1.5-m circular quadrats. Cedrus deodara is the national symbol of Pakistan and was dominant in the sampled communities. Because environmental variables determine vegetation types, we analyzed and evaluated edaphic and topographic factors. DCA-Ordination showed the major gradient as an amalgam of elevation (p<0.05) and slope (p<0.01) as the topographic factors correlated with species distribution. Soil variables were the factors of environmental significance along DCA axes. However, among these factors, Mg2+ , K + and N2+ contributed not more than 0.054% 0.20% and 0.073%, respectively, to variation along the first ordination axis. We conclude that the principal reason for weak or no correlation with many edaphic variables was the anthropogenic disturbance of vegetation. The understory vegetation was composed of perennial herbs in most communities and was most dense under the tree canopy. The understory vegetation strongly regulates tree seedling growth and regeneration patterns. We recommend further study of the understory vegetation using permanent plots to aid development of forest regeneration strategies. | Nasrullah Khan Syed Shahid Shaukat Moinuddin Ahmed Muhammad Faheem Siddiqui | 2013 | Journal of Forestry Research2013，24，2： | 8 |
| 8 | Current Status of Conventional and Molecular Interventions for Blast Resistance in Rice显示文摘Pyricularia oryzae anamorph of Magnaporthe oryzae is one of the most notorious fungal pathogens causing severe economic loss in rice production worldwide. Various methods, viz. cultural, biological and molecular approaches, are utilized to counteract this pathogen. Moreover, some tolerant or resistant rice varieties have been developed with the help of breeding programmes. Isolation and molecular characterization of different blast resistance genes now open the gate for new possibilities to elucidate the actual allelic variants of these genes via various molecular breeding and transgenic approaches. However, the behavioral pattern of this fungus breakups the resistance barriers in the resistant or tolerant rice varieties. This host-pathogen barrier will be possibly countered in future research by comparative genomics data from available genome sequence data of rice and M. oryzae for durable resistance. Present review emphasized fascinating recent updates, new molecular breeding approaches, transgenic and genomics approaches(i.e. mi RNA and genome editing) for the management of blast disease in rice. The updated information will be helpful for the durable, resistance breeding programme in rice against blast pathogen. | Deepti SRIVASTAVA Md SHAMIM Mahesh KUMAR Anurag MISHRA Pramila PANDEY Deepak KUMAR Prashant YADAV Mohammed Harrish SIDDIQUI Kapildeo Narayan SINGH | 2017 | Rice science2017，24，6： | 8 |
| 9 | Systematic review of emergent laparoscopic colorectal surgery for benign and malignant disease显示文摘Laparoscopic surgery has become well established in the management of both and malignant colorectal disease.The last decade has seen increasing numbers of surgeons trained to a high standard in minimallyinvasive surgery.However there has not been the same enthusiasm for the use of laparoscopy in emergency colorectal surgery.There is a perception that emergent surgery is technically more difficult and may lead to worse outcomes.The present review aims to provide a comprehensive and critical appraisal of the available literature on the use of laparoscopic colorectal surgery(LCS)in the emergency setting.The literature is broadly divided by the underlying pathology;that is,inflammatory bowel disease,diverticulitis and malignant obstruction.There were no randomized trials and the majority of the studies were case-matched series or comparative studies.The overall trend was that LCS is associated with shorter hospital stay,par or fewer complications but an increased operating time.Emergency LCS can be safely undertaken for both benign and malignant disease providing there is appropriate patient selection,the surgeon is adequately experienced and there are sufficient resources to allow for a potentially more complex operation. | Manish Chand Muhammed RS Siddiqui Ashish Gupta Shahnawaz Rasheed Paris Tekkis Amjad Parvaiz Alex H Mirnezami Tahseen Qureshi | 2014 | World Journal of Gastroenterology2014，20，45： | 7 |
| 10 | Defining response to radiotherapy in rectal cancer using magnetic resonance imaging and histopathological scales显示文摘AIM To define good and poor regression using pathology and magnetic resonance imaging(MRI) regression scales after neo-adjuvant chemotherapy for rectal cancer.METHODS A systematic review was performed on all studies up to December 2015, without language restriction, t h a t w e r e i d e n t i f i e d f r o m M E D L I N E, C o c h r a n e Controlled Trials Register(1960-2015), and EMBASE(1991-2015). Searches were performed of article bibliographies and conference abstracts. MeS H and text words used included 'tumour regression', 'mr TRG', 'poor response' and 'colorectal cancers'. Clinical studies using either MRI or histopathological tumour regression grade(TRG) scales to define good and poor responders were included in relation to outcomes [local recurrence(LR), distant recurrence(DR), disease-free survival(DFS), and overall survival(OS)]. There was no age restriction or stage of cancer restriction for patient inclusion. Data were extracted by two authors working independently and using pre-defined outcome measures.RESULTS Quantitative data(prevalence) were extracted and analysed according to meta-analytical techniques using comprehensive meta-analysis. Qualitative data(LR, DR, DFS and OS) were presented as ranges. The overall proportion of poor responders after neo-adjuvant chemoradiotherapy(CRT) was 37.7%(95%CI: 30.1-45.8). There were 19 different reported histopathological scales and one MRI regression scale(mrT RG). Clinical studies used nine and six histopathological scales for poor and good responders, respectively. All studies using MRI to define good and poor response used one scale. The most common histopathological definition for good response was the Mandard grades 1 and 2 or Dworak grades 3 and 4; Mandard 3, 4 and 5 and Dworak 0, 1 and 2 were used for poor response. For histopathological grades, the 5-year outcomes for poor responders were LR 3.4%-4.3%, DR 14.3%-20.3%, DFS 61.7%-68.1% and OS 60.7-69.1. Good pathological response 5-year outcomes were LR 0%-1.8%, DR 0%-11.6%, DFS 78.4%-86.7%, and OS 77.4%-88.2%. A poor response on MRI(mr TRG 4,5) resulted in 5-year LR 4%-29%, DR 9%, DFS 31%-59% and OS 27%-68%. The 5-year outcomes with a good response on MRI(mrT RG 1,2 and 3) were LR 1%-14%, DR 3%, DFS 64%-83% and OS 72%-90%.CONCLUSION For histopathology regression assessment, Mandard 1, 2/Dworak 3, 4 should be used for good response and Mandard 3, 4, 5/Dworak 0, 1, 2 for poor response. MRI indicates good and poor response by mr TRG1-3 and mrT RG4-5, respectively. | Muhammed RS Siddiqui Jemma Bhoday Nicholas J Battersby Manish Chand Nicholas P West Al-Mutaz Abulafi Paris P Tekkis Gina Brown | 2016 | World Journal of Gastroenterology2016，22，37： | 6 |
| 11 | Endoscopic retrograde cholangiopancreatography in cirrhosis-a systematic review and meta-analysis focused on adverse events显示文摘AIM To investigate indications and outcomes of endoscopic retrograde cholangiopancreatography(ERCP) in cirrhotics, especially adverse events. Patients with cirrhosis undergoing ERCP are believed to have increased risk. However, there is a paucity of literature describing the indications and outcomes of ERCP procedures in patients with cirrhosis, especially focusing on adverse events.METHODS We performed a systematic appraisal of major literature databases, including PubMed and EMBASE, with a manual search of literature from their inception until April 2017.RESULTS A total of 6,505 patients from 15 studies were analyzed(male ratio 59%, mean age 59 years), 11% with alcoholic and 89% with non-alcoholic cirrhosis, with 56.2% Child-Pugh class A, and 43.8% class B or C. Indications for ERCP included choledocholithiasis 60.9%, biliary strictures 26.2%, gallstone pancreatitis 21.1% and cholangitis 15.5%. Types of interventions included endoscopic sphincterotomy 52.7%, biliary stenting 16.7% and biliary dilation 4.6%. Individual adverse events included hemorrhage in 4.58%(95%CI: 2.77-6.75%, I^2 = 85.9%), post-ERCP pancreatitis(PEP) in 3.68%(95%CI: 1.83-6.00%, I^2 = 89.5%), cholangitis in 1.93%(95%CI: 0.63-3.71%, I^2 = 87.1%) and perforation in 0.00%(95%CI: 0.00-0.23%, I^2 = 37.8%). Six studies were used for comparison of ERCPrelated complications in cirrhosis vs non-cirrhosis, which showed higher overall rates of complications in cirrhosis patients with pooled OR of 1.63(95%CI: 1.27-2.09, I2 = 65%): higher rates of hemorrhage with OR of 2.05(95%CI: 1.62-2.58, I^2 = 2.1%) and PEP with OR of 1.33(95%CI: 1.04-1.70, I2=65%), but similar cholangitis rates with OR of 1.23(95%CI: 0.67-2.26, I^2 = 44.3%).CONCLUSION There is an overall higher rate of adverse events related to ERCP in patients with cirrhosis, especially hemorrhage and PEP. A thorough risk/benefit assessment should be performed prior to undertaking ERCP in patients with cirrhosis. | Shailender Singh Mashiana Amaninder Singh Dhaliwal Harlan Sayles Banreet Dhindsa Ji Won Yoo Qing Wu shailender singh Ali A Siddiqui Gordon Ohning Mohit Girotra Douglas G Adler | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，11： | 6 |
| 12 | A review of recent advancements in finite element formulation for sandwich plates显示文摘Use of composite structures is exponentially growing in different fields due to their higher strength-to-weight ratio. This application trend requires that accurate theoretical explanations and their finite element models be developed for analyzing sandwich plates before finalizing the designs. This paper reviews the recent research trends of finite element formulations developed for analyzing sandwich plates. This paper reviews the finite element models developed after the year 2000. Initially, the finite element formulations based on first order shear deformation theory, higher order shear deformation theories, mixed solid-shell elements, zig-zag theories and global–local theories are presented. Then, some finite element formulations developed to analyze a very new class of structures called piezoelectric structures are presented. At the end, some formulations to analyze a very critical phenomenon called buckling are presented. | Shehzaib IRFAN Faisal SIDDIQUI | 2019 | Chinese Journal of Aeronautics2019，32，4： | 5 |
| 13 | Investigation on the process parameters of TIG-welded aluminum alloy through mechanical and microstructural characterization显示文摘Multi-pass TIG welding was conducted on plates(15×300×180 mm^(3))of aluminum alloy Al-5083 that usually serves as the component material in structural applications such as cryogenics and chemical processing industries.Porosity formation and solidification cracking are the most common defects when TIG welding Al-5083 alloy,which is sensitive to the welding heat input.In the experiment,the heat input was varied from 0.89 kJ/mm to 5 kJ/mm designed by the combination of welding torch travel speed and welding current.Tensile,micro-Vicker hardness and Charpy impact tests were executed to witness the impetus response of heat input on the mechanical properties of the joints.Radiographic inspection was performed to assess the joint’s quality and welding defects.The results show that all the specimens displayed inferior mechanical properties as compared to the base alloy.It was established that porosity was progressively abridged by the increase of heat input.The results also clinched that the use of medium heat input(1-2 kJ/mm)offered the best mechanical properties by eradicating welding defects,in which only about 18.26% of strength was lost.The yield strength of all the welded specimens remained unaffected indica ted no influence of heat input.Partially melted zone(PMZ)width also affected by heat input,which became widened with the increase of heat input.The grain size of PMZ was found to be coarser than the respective grain size in the fusion zone.Charpy impact testing revealed that the absorbed energy by low heat input specimen(welded at high speed)was greater than that of high heat input(welded at low speed)because of low porosity and the formation of equiaxed grains which induce better impact toughness.Cryogenic(-196℃)impact testing was also performed and the results corroborate that impact properties under the cryogenic environment revealed no appreciable change after welding at designated heat input.Finally,Macro and micro fractured surfaces of tensile and impact specimens were analyzed using Stereo and Scanning Electron Microscopy(SEM),which have supported the experimental findings. | Muhammad Samiuddin Jing-long Li Muhammad Taimoor Mohammad Nouman Siddiqui Sumair Uddin Siddiqui Jiang-tao Xiong | 2021 | Defence Technology(防务技术)2021，17，4： | 5 |
| 14 | Neuroprotective Effect of Chrysophanol as a PI3K/AKT/mTOR Signaling Inhibitor in an Experimental Model of Autologous Blood-induced Intracerebral Hemorrhage显示文摘Objective Intracerebral hemorrhage(ICH)refers to predominant,sporadic,and non-traumatic bleeding in the brain parenchyma.The PI3K/AKT/mTOR signaling pathway is an important signal transduction pathway regulated by enzyme-linked receptors and has many biological functions in mammals.It plays a key role in neuronal metabolism,gene expression regulation,and tissue homeostasis in the healthy and diseased brain.Methods In the present study,the role of the PI3K/AKT/mTOR pathway inhibitor chrysophanol(CPH)(10 mg/kg and 20 mg/kg,orally)in the improvement of ICH-associated neurological defects in rats was investigated.Autologous blood(20µL/5 min/unilateral/intracerebroventricular)mimics ICH-like defects involving cellular and molecular dysfunction and neurotransmitter imbalance.The current study also included various behavioral assessments to examine cognition,memory,and motor and neuromuscular coordination.The protein expression levels of PI3K,AKT,and mTOR as well as myelin basic protein and apoptotic markers,such as Bax,Bcl-2,and caspase-3,were examined using ELISA kits.Furthermore,the levels of various neuroinflammatory cytokines and oxidative stress markers were assessed.Additionally,the neurological severity score,brain water content,gross brain pathology,and hematoma size were used to indicate neurological function and brain edema.Results CPH was found to be neuroprotective by restoring neurobehavioral alterations and significantly reducing the elevated PI3K,AKT,and mTOR protein levels,and modulating the apoptotic markers such as Bax,Bcl-2,and caspase-3 in rat brain homogenate.CPH substantially reduced the inflammatory cytokines like interleukin(IL)-1β,IL-6,and tumor necrosis factor-α.CPH administration restored the neurotransmitters GABA,glutamate,acetylcholine,dopamine,and various oxidative stress markers.Conclusion Our results show that CPH may be a promising therapeutic approach for overcoming neuronal damage caused by the overexpression of the PI3K/AKT/mTOR signaling pathway in ICH-induced neurological dysfunctions in rats. | Kuldeep Singh JADAUN Sidharth MEHAN Aarti SHARMA Ehraz Mehmood SIDDIQUI Sumit KUMAR NaifALSUHAYMI | 2022 | Current Medical Science2022，42，2： | 5 |
| 15 | Crohn's disease with gastroduodenal involvement: Diagnostic approach显示文摘Crohn's disease(CD) is a chronic idiopathic inflammatory disease of gastrointestinal tract characterizedby segmental and transmural involvement of gastrointestinal tract. Ileocolonic and colonic/anorectal is a most common and account for 40% of cases and involvement of small intestine is about 30%. Isolated involvement of stomach is an extremely unusual presentation of the disease accounting for less than 0.07% of all gastrointestinal CD. To date there are only a few documented case reports of adults with isolated gastric CD and no reports in the pediatric population. The diagnosis is difficult to establish in such cases with atypical presentation. In the absence of any other source of disease and in the presence of nonspecific upper gastrointestinal endoscopy and histological findings, serological testing can play a vital role in the diagnosis of atypical CD. Recent studies have suggested that perinuclear anti-neutrophil cytoplasmic antibody and anti-Saccharomycescervisia antibody may be used as additional diagnostic tools. The effectiveness of infliximab in isolated gastric CD is limited to only a few case reports of adult patients and the long-term outcome is unknown. | Sachin B Ingle Baban D Adgaonkar Nawab P Jamadar Saleha Siddiqui Chitra R Hinge | 2015 | World Journal of Clinical Cases2015，3，6： | 5 |
| 16 | Cancer models in preclinical research:A chronicle review of advancement in effective cancer research显示文摘Cancer is a major stress for public well-being and is the most dreadful disease.The models used in the discovery of cancer treatment are continuously changing and extending toward advanced preclinical studies.Cancer models are either naturally existing or artificially prepared experimental systems that show similar features with human tumors though the heterogeneous nature of the tumor is very familiar.The choice of the most fitting model to best reflect the given tumor system is one of the real difficulties for cancer examination.Therefore,vast studies have been conducted on the cancer models for developing a better understanding of cancer invasion,progression,and early detection.These models give an insight into cancer etiology,molecular basis,host tumor interaction,the role of microenvironment,and tumor heterogeneity in tumor metastasis.These models are also used to predict novel can-cer markers,targeted therapies,and are extremely helpful in drug development.In this review,the potential of cancer models to be used as a platform for drug screening and therapeutic discoveries are highlighted.Although none of the cancer models is regarded as ideal because each is associated with essential caveats that restraint its application yet by bridging the gap between preliminary cancer research and transla-tional medicine.However,they promise a brighter future for cancer treatment. | Humna Sajjad Saiqa Imtiaz Tayyaba Noor Yusra Hasan Siddiqui Anila Sajjad Muhammad Zia | 2021 | Animal Models and Experimental Medicine2021，4，2： | 5 |
| 17 | Pharmacological properties of Datura stramonium L. as a potential medicinal tree:An overview显示文摘India has a great wealth of various naturally occurring plant drugs which have great potential pharmacological activities.Datura stramonium(D.stramonium is one of the widely well known folklore medicinal herbs.The troublesome weed,D.stramonium is a plant with both poisonous and medicinal preperties and has been proven to have great pharmacological potential with a great utility real usage in folklore medicine.D.stromonium has been scientifically proven to contain alkaloids,tannins,carbohydrates and proteins.This plant has contributed various pharmacological actions in the scientific field of Indian systems of medicines like analgesic and antiasthmatic activities.The present paper presents an exclusive review work on the ethnomedical,phytochemical,pharmacological activities of this plant. | Priyanka Soni Anees Ahmad Siddiqui Jaya Dwivedi Vishal Soni | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，12： | 5 |
| 18 | Characterization of Embryonic Stages through Variations in the Egg's Contents in Spodoptera fitura显示文摘 | F. Perveen H. Ahmed F. M. Abbasi N. Y. Siddiqui A. Gul | 2010 | Journal of Agricultural Science and Technology2010，4，5： | 5 |
| 19 | Mechanical, tribological and anti-corrosive properties of polyaniline/graphene coated Mg-9Li-7Al-1Sn and Mg-9Li-5Al-3Sn-1Zn alloys显示文摘The mechanical,tribological and corrosion protection offered to Mg-9Li-7Al-1Sn and Mg-9Li-5Al-3Sn-1Zn alloys by the epoxy coating containing polyaniline/graphene(PANI/Gr)pigments is undertaken in the current work.PANI/Gr containing coatings were observed to be strongly adherent with a higher scratch hardness(Hs)and plowing hardness(Hp),i.e.Hsof 0.43 GPa,and Hpof 0.61 GPa,respectively when compared to that of neat epoxy coating(Hsof 0.17 GPa,and Hpof 0.40 GPa,respectively).Due to their higher Hsand Hpvalues,PANI/Gr based coatings displayed an enhanced wear resistance(Wear volume,Wv=4.53×10^-3 m^3)than that of neat epoxy coating(Wv=5.15×10^-3 m^3).The corrosion protection efficiency in corrosive environment of 3.5 wt%NaCl solution was obtained to be>99% for PANI/Gr containing coatings when compared to that of neat epoxy coating.The charge-transfer resistance(R(ct))of the PANI/Gr containing coatings were estimated to be>10^6 cm^2,which indicates their highly protective nature when compared to that of neat epoxy coating(R(ct)10^5 Ω cm^2).Hence,PANI/Gr containing coatings can be potentially used for wear resistance and corrosion protection applications in marine environments. | Rita Maurya Abdul Rahim Siddiqui Prvan Kumar Katiyar Kantesh Balani | 2019 | Journal of Materials Science & Technology2019，35，8： | 4 |
| 20 | Biosynthesis of Flower-Shaped CuO Nanostructures and Their Photocatalytic and Antibacterial Activities显示文摘Copper oxide nanoflowers(CuO-NFs)have been synthesized through a novel green route using Tulsi leaves-extracted eugenol(4-allyl-2-methoxyphenol)as reducing agent.Characterizations results reveal the growth of crystalline singlephase CuO-NFs with monoclinic structure.The prepared CuO-NFs can effectively degrade methylene blue with 90%efficiency.They also show strong barrier against E.coli(27±2 mm)at the concentration of 100μg mL−1,while at the concentration of 25μg mL−1 weak barrier has been found against all examined bacterial organisms.The results provide important evidence that CuO-NFs have sustainable performance in methylene blue degradation as well as bacterial organisms. | Hafsa Siddiqui MSQureshi Fozia Zia Haque | 2020 | Nano-Micro Letters2020，12，2： | 4 |
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