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| 1 | Prevalence of Helicobacter pylori infection and atrophic gastritis in patients with dyspeptic symptoms in Myanmar显示文摘AIM: To survey the detailed analyses for Helicobacter pylori(H. pylori) infection and gastric mucosal status in Myanmar.METHODS: A total of 252 volunteers with dyspeptic symptoms(155 female and 97 male; mean age of 43.6 ± 14.2 years) was participated in Yangon and Mandalay. The status of H. pylori infection was determined based on 5 different tests including rapid urease test, culture, histology, immunohistochemistry and serology. Histological scores were evaluated according to the update Sydney system and the Operative Link for Gastritis Assessment system. Pepsinogen(PG)Ⅰand PG Ⅱ were measured using enzyme-linked immunosorbent assays.RESULTS: The overall prevalence of H. pylori infectionwas 48.0%. There was no relationship between age and infection rate. Even in young group(less than 29 years old), the H. pylori infection rate was relatively high(41.9%). The prevalence of H. pylori infection was significantly higher in Yangon than that of Mandalay. H. pylori infection was significantly associated with the presence of gastric mucosal atrophy. All 7 subjects with peptic ulcer were infected with H. pylori. Although H. pylori-positive subjects showed stronger gastritis than H. pylori-negative subjects, most cases had mild gastritis.CONCLUSION: We revealed the prevalence of H. pylori infection in patients with dyspeptic symptoms in Myanmar. The H. pylori infection was a risk factor for peptic ulcer and stronger gastritis. | Thein Myint Seiji Shiota Ratha-korn Vilaichone New Ni Than Than Aye Miyuki Matsuda Trang Thi Huyen Tran Tomohisa Uchida Varocha Mahachai Yoshio Yamaoka | 2015 | World Journal of Gastroenterology2015，21，2： | 10 |
| 2 | 多普勒组织成像技术评价左心室扭转重构:标记磁共振成像验证研究 | Notomi Y. Setser R.M. Shiota T. J.D. Thomas 苏畅 | 2005 | 世界核心医学期刊文摘(心脏病学分册)2005，0，9： | 10 |
| 3 | Extremely high prevalence of Helicobacter pylori infection in Bhutan显示文摘AIM: To revealed the prevalence of Helicobacter pylori (H. pylori ) infection in the Bhutanese population. METHODS: We recruited a total of 372 volunteers (214 females and 158 males; mean age of 39.6 ± 14.9 years) from three Bhutanese cities (Thimphu, Punaka, and Wangdue). The status of H. pylori infection was determined based on five different tests: the rapid urease test (CLO test), culture, histology, immunohistochemistry (IHC), and serum anti H. pylori -antibody. RESULTS: The serological test showed a significantly higher positive rate compared with the CLO test, culture, histology and IHC (P < 0.001, P < 0.001, P=0.01, and P=0.01, respectively). When the subjects were considered to be H. pylori positive in the case of at least one test showing a positive result, the overall prevalence of H. pylori infection in Bhutan was 73.4%. The prevalence of H. pylori infection significantly decreased with age (P < 0.01). The prevalence of H. pylori infection was lower in Thimphu than in Punakha and Wangdue (P=0.001 and 0.06, respectively). The prevalence of H. pylori infection was significantly higher in patients with peptic ulcers than in those with gastritis (91.4% vs 71.3%, P=0.003). CONCLUSION: The high incidence of gastric cancer in Bhutan may be attributed to the high prevalence of H. pylori infection. | Ratha-korn Vilaichone Varocha Mahachai Seiji Shiota Tomohisa Uchida Thawee Ratanachu-ek Lotay Tshering Nguyen Lam Tung Toshio Fujioka Masatsugu Moriyama Yoshio Yamaoka | 2013 | World Journal of Gastroenterology2013，19，18： | 8 |
| 4 | 实时三维超声心动图对右心室功能及三尖瓣环运动的评价显示文摘目的 :应用实时三维超声心动图检查分析三尖瓣环运动和右室收缩功能的关系。方法 :2 7例包括健康志愿者 1 4例 ,接受心脏移植术后患者 7例 ,扩张型心肌病 3例 ,冠心病 2例 ,先天性心脏病 1例 ,所有实验对象均接受三维超声检查。将采集的实时三维图像转移至计算机图像分析仪上。从心尖将右心室三维图像沿右室长轴分成 9个切面 (每个切面间隔 2 0度 )。在舒张末期及收缩末期分别标定出三尖瓣环三维空间位置。计算机描绘并测量出不同时期三尖瓣环面积、周长及运动距离。利用实时三维超声的 C—平面 ,我们测量出三维超声的右心室舒张末期及收缩末期容积 ,并计算出右室射血分数。结果 :右心室射血分数平均为 48% (2 1 %~ 6 3% )。三尖瓣环空间运动距离为 1 5 mm。三尖瓣环面积改变为 1 7.7% ,周长改变为 33.3%。右室射血分数与三尖瓣环运动距离有很好的相关性 (y=2 .2 x+1 5 .5 ,r=0 .88,P<0 .0 1 ) ,但与瓣环的面积及周长改变无关。结论 :用三尖瓣环运动距离来评价右室收缩功能是一种有用的方法。 | 徐勇 智光 李天德 Takahiro Shiota Jian Xin Qin James | 2000 | 中国超声医学杂志2000，16，9： | 7 |
| 5 | Antibiotics resistance rate of Helicobacter pylori in Bhutan显示文摘AIM:To survey the antibiotic resistance pattern of Helicobacter pylori(H.pylori)strains isolated from Bhutanese population.METHODS:We isolated 111 H.pylori strains from the gastric mucosa of H.pylori-infected patients in Bhutan in 2010.The Epsilometer test was used to determine the minimum inhibitory concentrations(MICs)of amoxicillin(AMX),clarithromycin(CLR),metronidazole(MNZ),levofloxacin(LVX),ciprofloxacin(CIP),and tetracycline(TET).RESULTS:Nineteen of the isolated H.pylori strains were susceptible to all antibiotics tested.The isolated strains showed the highest rate of antibiotic resistance to MNZ(92/111,82.9%).Among the 92 MNZresistant strains,74 strains(80.4%)showed high-level resistance(MIC≥256 g/mL).Three strains were resistance to LVX(2.7%).These strains were also resistance to CIP.None of the strains showed resistance to CLR,AMX and TET.CONCLUSION:CLR-based triple therapy is a more effective treatment approach over MNZ-based triple therapy for H.pylori infection in Bhutan. | Ratha-korn Vilaichone Yoshio Yamaoka Seiji Shiota Thawee Ratanachu-ek Lotay Tshering Tomohisa Uchida Toshio Fujioka Varocha Mahachai | 2013 | World Journal of Gastroenterology2013，19，33： | 6 |
| 6 | Ten-year prospective follow-up of histological changes at five points on the gastric mucosa as recommended by the updated Sydney system after Helicobacter pylori eradication显示文摘 | Masaaki Kodama Kazunari Murakami Tadayoshi Okimoto Ryugo Sato Masahiro Uchida Takashi Abe Seiji Shiota Yoshifumi Nakagawa Kazuhiro Mizukami Toshio Fujioka | 2012 | Journal of Gastroenterology2012，，4： | 4 |
| 7 | The Pathogenesis of Nonalcoholic Steatohepatitis and Other Fatty Liver Diseases: A Four-Step Model including the Role of Lipid Release and Hepatic Venular Obstruction in the Progression to Cirrhosis显示文摘 | Ian Wanless Koji Shiota | 2004 | Semin Liver Dis2004，，01： | 3 |
| 8 | The significance of virulence factors in H elicobacter pylori显示文摘 | Seiji Shiota Rumiko Suzuki Yoshio Yamaoka | 2013 | Journal of Digestive Diseases2013，，7： | 3 |
| 9 | The Incidence of Primary Antibiotic Resistance of Helicobacter pylori in Vietnam显示文摘 | Tran T. Binh Seiji Shiota Lam T. Nguyen Dung D.Q. Ho Hai H. Hoang Long Ta Dung T. Trinh Toshio Fujioka Yoshio Yamaoka | 2013 | Journal of Clinical Gastroenterology2013，，3： | 2 |
| 10 | Evaluation of Pesticide Residues in Mango by a Multi-residue Analysis and GC/MS Triple Quadrupole显示文摘 | Claudia Helena Pastor Ciscato Kumi Shiota Ozawa Claudia Maria Barbosa Amir Bertoni Gebara | 2015 | Journal of Agricultural Science and Technology(B)2015，5，8： | 2 |
| 11 | Molecular epidemiology, population genetics, and pathogenic role of Helicobacter pylori显示文摘 | Rumiko Suzuki Seiji Shiota Yoshio Yamaoka | 2011 | Infection Genetics and Evolution2011，，2： | 2 |
| 12 | Pathomorphologic study on the mechanism of fatty change in small hepatocellular carcinoma of humans显示文摘 | Rumiko Kutami Yutaka Nakashima Osamu Nakashima Koji Shiota Masamichi Kojiro | 2000 | Journal of Hepatology2000，，2： | 2 |
| 13 | Seroprevalence of Helicobacter pylori infection and gastric mucosal atrophy in Bhutan, a country with a high prevalence of gastric cancer显示文摘 | Seiji Shiota Varocha Mahachai Ratha-korn Vilaichone Thawee Ratanachu-ek Lotay Tshering Tomohisa Uchida Osamu Matsunari Yoshio Yamaoka | 2013 | Journal of Medical Microbiology2013，，1： | 2 |
| 14 | Cell-specific roles of glucokinase in glucose homeostasis显示文摘 | Postic C Shiota M Magnuson M M | 2001 | Recent Prog Horm Res2001，56，： | 1 |
| 15 | Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1lymphoma cell line,AMS3显示文摘 | Shiota M Fujimoto J Semba T | 1994 | Oncogene1994，9，： | 1 |
| 16 | Percutaneous mitral valve repair for chomic ischemic mitral regurgitation: a real-time three-dimensional echocardiography study in an ovine model显示文摘 | Daimon M Shiota T Gillinov AM | 2005 | Circulation2005，111，： | 1 |
| 17 | Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for 0^6 - alkylgua- nine显示文摘 | Tano K Shiota S Collier J | 1990 | Proc Natl Acad Sci USA1990，87，2： | 1 |
| 18 | Transgenic rice containing human CYP2B6 detoxifies various classes of herbicides 显示文摘 | Hirose S Kawahigashi H Ozawa K Shiota N Inui H Ohkawa H Ohkawa Y | 2005 | Journal of Agricultural and Food Chemistry2005，53，9： | 1 |
| 19 | Inhibition of RSK/YB-1 signaling enhances the anti-cancer effect of enzalutamide in pros- rate cancer 显示文摘 | Shiota M Yokomizo A Takeuchi A | 2014 | Prostate2014，74，9： | 1 |
| 20 | Inhibition of RSK/YB-1signaling enhances the anti-cancer effect of enzalutamide in prostate cancer显示文摘 | Shiota M Yokomizo A Takeuchi A | 2014 | Prostate2014，74，9： | 1 |
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