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| 1 | Overexpression of ADAM9 in non-small cell lung cancer correlates with brain metastasis显示文摘The 'a disintegrin and metalloprotease' (ADAM) family contributes to regulation of the cell-cell and cell-matrix interactions that are critical determinants of malignancy. To determine the relationship between metastasis and ADAM proteins, we compared the mRNA levels of ADAM9,-10,-12,-15, and-17 in sublines of an EBC-1 lung cancer cell line that were highly metastatic to either brain or bone. ADAM9 mRNA levels were significantly higher in highly brain-metastatic sublines than in the parent or highly bonemetastalic sublines. To elucidate the role ofADAM9 in brain metastasis, we stably transfected A549 and EBC-1 cells with a fulllength ADAM9 expression vector. Compared with mock-transfectants, ADAM9 overexpression resulted in increased invasive capacity | Shintani Y Higashiyama S Ohta M Hirabayashi H Yamamoto S Yoshimasu T Matsuda H Matsuura N | 2004 | 中国神经肿瘤杂志2004，2，2： | 36 |
| 2 | Troglitazone induces GIUT4 translocation in L6 myotubes 显示文摘 | Yonemitsu S Nishimura H Shintani M | 2001 | Diabetes2001，50，： | 1 |
| 3 | lesioning of the rat basal forebrain leads to memory impairments in passive and active avoidance tasks显示文摘 | Miyamoto M shintani M Gaoka A | 1985 | Brain Res1985，328，： | 1 |
| 4 | Can News be a Major Source of Aggregate Fluctuations?A Bayesian DSGE Approach显示文摘 | Fujiwara I Hirose Y Shintani M | 2011 | Journal of Money Credit and Banking2011，43，1： | 1 |
| 5 | High frequency of homo- zygous deletion and methylation of p16 (INK4A)gene in oral squa- mous cell carcinomas 显示文摘 | Nakahara Y Shintani S Mihara M | 2001 | Cancer Lett2001，163，2： | 1 |
| 6 | Ghrelin, an Endogenous Growth Hormone Secretagogue, Is a Novel Orexigenic Peptide That Antagonizes Leptin Action Through the Activation of Hypothalamic Neuropeptide Y/Y1 Receptor Pathway显示文摘 | Shintani M Ogawa Y Ebihara K | 2001 | Diabetes2001，50，： | 1 |
| 7 | Ghrelin,an Endogenous Growth Hormone Secretagogue,is a Novel Orexigenic Peptide That an Tagonizes Leptin Action Through the Activation of Hypothalamic Neuropeptide Y/Y1 Pathway显示文摘 | SHINTANI M OGAWA Y EBIHARA K | 2002 | Diabetes2002，282，6： | 1 |
| 8 | Lesioning of the rat basal forebrain leads to memory impairments in pas- sive and active avoidance tasks 显示文摘 | Miyamoto M Shintani M Nagaoka A | 1985 | Brain Res1985，328，1： | 1 |
| 9 | Ambulatory blood pressure, blood pressure variability and the prevalence of carotid artery alteration: the Ohasama study显示文摘 | Shintani Y Kikuya M Hara A | 2007 | J Hypertens2007，25，8： | 1 |
| 10 | Reduction of p-12DOC-1 expression is a negative prognostic indicator in patients with surgically resected oral squamous cell carcinoma显示文摘 | SHINTANI S MIHARA M TERAKADO N | 2001 | Clin Cancer Res2001，7，： | 1 |
| 11 | Overexpression of CDK2 is a prognostic indicator of oral cancer progression显示文摘 | Mihara M Shintani S Nakahara Y | 2001 | JPN J Cancer Res2001，92，3： | 1 |
| 12 | Anti-epidermal growth factor receptor monoclonal antibody 225 upregulates p27 (KIP1) and p15 (INK4B) and induces G1 arrest in oral squamous carcinoma cell lines显示文摘 | Kiyota A Shintani S Mihara M | 2002 | Oncol2002，63，1： | 1 |
| 13 | Ambulatory blood pressure, blood pressure variability and the prevalence of cm'otid artery al- treation : the Ohasama study 显示文摘 | Shintani Y Kikuya M Hara A | 2007 | J Hyperterns2007，25，8： | 1 |
| 14 | Apelin is a novel angiogenic factor in retinal endothelial cells显示文摘 | Kasai A Shintani N Oda M | | 0，，： | 1 |
| 15 | Lesioning of the rat basal forebrain leads to memory impairments in passive and active avoidance tasks显示文摘 | Miyamoto M Shintani M Nagaoka A | 1985 | Brain Res1985，328，1： | 1 |
| 16 | New prognostic indicator for non-small-cell lung cancer, quantitation of thymidylate synthase by real-time reverse transcription polymerase chain reaction显示文摘 | Shintani Y Ohta M Hirabayashi H | 2003 | Int J Cancer2003，104，6： | 1 |
| 17 | Apelin is a novel angiogenic factor in retinal endothelial cells显示文摘 | Kasai A Shintani N Oda M | | 0，，02： | 1 |
| 18 | Insulin resistance,role of leptin and leptin receptor显示文摘 | Ogawa Y Nakao K | 2000 | Nippon Rinsho2000，58，： | 1 |
| 19 | Expression of cell cycle control proteins in normal epithelium, premalignant and malignant lesions of oral cavity显示文摘 | Shintani S Mihara M Nakahara Y | 2002 | Oral Oncol2002，38，3： | 1 |
| 20 | Ghrelin, an endogenous growth hormone secretagogue,is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway 显示文摘 | Shintani M Ogawa Y Ebihara K | 2001 | Am Diabe Assoc2001，50，2： | 1 |
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