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| 1 | Chemotherapy plus percutaneous radiofrequency ablation in patients with inoperable colorectal liver metastases显示文摘AIM:To access the efficacy of chemotherapy plus radiofrequency ablation(RFA)as one line of treatment in inoperable colorectal liver metastases.METHODS:Eligible patients were included in three PhaseⅡstudies.In the first study percutaneous RFA was used first followed by 6 cycles of 5-fluorouracil,leucovorin and irinotecan combination(FOLFIRI)(adjunctive chemotherapy trial).In the other two,chemotherapy(FOLFIRI or 5-fluorouracil,leucovorin and oxaliplatin combination)up to 12 cycles was used first with percutaneous RFA offered to responding patients (primary chemotherapy trials).RESULTS:Thirteen patients were included in the adjunctive chemotherapy trial and 17 in the other two.At inclusion they had 1-4 liver metastases(up to 6.5 cm in size).Two patients died during chemotherapy.All patients in the adjunctive chemotherapy trial and 44%in the primary chemotherapy studies had their metastases ablated.Median PFS and overall survival in the adjunctive study were 13 and 24 mo respectively while in the primary chemotherapy studies they were 10 and 21 mo respectively.Eighty one percent of the patients had tumour relapse in at least one previously ablated lesion.CONCLUSION:Chemotherapy plus RFA in patients with low volume inoperable colorectal liver metastases seems safe and relatively effective.The high local recurrence rate is of concern. | Joseph Sgouros James Cast Krishna K Garadi Maria Belechri David J Breen John RT Monson Anthony Maraveyas | 2011 | World Journal of Gastrointestinal Oncology2011，3，4： | 4 |
| 2 | A prospective cross-over study using a sphincterotome and a guidewire to increase the success rate of common bile duct cannulation显示文摘AIM: During endoscopic retrograde cholangiopancreatography (ERCP), selective cannulation of the common bile duct (CBD) is required in most of the cases.METHODS: From June 2001 till December 2002, all patients referred to our unit for ERCP were considered for entry into the study. Selective CBD cannulation was first attempted with a standard catheter with or without the use of a guidewire. In cases, where CBD cannulation was considered unsuccessful, patients were crossed over to a double-lumen sphincterotome and a guidewire. All patients were hospitalized for 24 h after the procedure in order to assess the incidence of post-ERCP complications.RESULTS: The study sample consisted of 158 patients.Selective CBD cannulation using a standard ERCP catheter with or without the assistance of a guidewire, was accomplished in 129 patients (success rate: 81.65%).From the 29 patients who were crossed over to a sphincterotome and a guidewire, selective CBD cannulation was achieved in 24; the overall success rate rising to 96.8%. Meanwhile, the use of this technique did not increase the incidence of post-ERCP complications.CONCLUSION: The use of a sphincterotome and a guidewire increases the success rate of selective bile duct cannulation in cases that this has not been accomplished with a standard catheter. | Georgios Karamanolis Aikaterini Katsikani Nikos Viazis Gerasimos Stefanidis Spilios Manolakopoulos Spiros Sgouros Efthimia Papadopoulou Apostolos Mantides | 2005 | World Journal of Gastroenterology2005，11，11： | 3 |
| 3 | 消化性溃疡出血患者使用生长抑素抑制胃酸分泌效果优于潘托拉唑:一项前瞻性、随机、安慰剂对照试验 | Avgerinos A. Sgouros S. Viazis N. 陈云茹 | 2005 | 世界核心医学期刊文摘(胃肠病学分册)2005，0，9： | 2 |
| 4 | Radionuclide photon dose kernel for internal emitter dosimetry 显示文摘 | Furhang EE Sgouros G Chui CS | 1996 | Med Phys1996，23，： | 1 |
| 5 | Gemcitabine versus gemcitabine plus dalteparin thromboprophylaxis in pancreatic cancer显示文摘 | A. Maraveyas J. Waters R. Roy D. Fyfe D. Propper F. Lofts J. Sgouros E. Gardiner K. Wedgwood C. Ettelaie G. Bozas | 2011 | European Journal of Cancer2011，，9： | 1 |
| 6 | Human DNA repair genes 显示文摘 | Wood R D Mitchell M Sgouros J | 2001 | Science2001，291，： | 1 |
| 7 | Early decompressive craniectomy may be effective in the treatment of refractory intracranial hypertension after traumatic brain injury显示文摘 | Josan Sgouros | 2006 | Childs Nerv Syst2006，22，10： | 1 |
| 8 | Assessment of the influence of operative factors in the success of endoscopic third ventriculostomy in children显示文摘 | Kombogiorgas D Sgouros S | 2006 | Childs Nerv Syst2006，22，： | 1 |
| 9 | The clinical valie of electroen-cephjalogram/magnetic resonance imaging co-registration and tree-dimensional reconstruction in the surgical treatment of epileptogenic lesion显示文摘 | Seri S Natarajan K | 2001 | Childs Nerv Syst2001，17，3： | 1 |
| 10 | Human DNA repair genes显示文摘 | Wood RD Mitchell M Sgouros J | 2001 | Sci2001，291，： | 1 |
| 11 | Intra-craniaI volume change in childhood显示文摘 | SGOUROS S GOLDIN J H HOCKLEY A D | | 0，，02： | 1 |
| 12 | Targeted alpha particle immunotherapy for myeloid leukemia显示文摘 | Jurcic JG Larson SM Sgouros G | 2002 | Blood2002，100，： | 1 |
| 13 | Incidence of vascular malformations in spontaneous intra-cerebral haemorrhage in children显示文摘 | Papadias A Taha A Sgouros S | 2007 | Childs Nerv Syst2007，23，8： | 1 |
| 14 | The International Infant Hydrocephalus Study: concept and rational 显示文摘 | Sgouros S Kulkharni AV Constantini S | 2006 | Childs Nerv Syst2006，22，： | 1 |
| 15 | Risk factors for developing epilepsy after craniotomy in children 显示文摘 | Kombogiorgas D Jatavallabhula NS Sgouros S | 2006 | Childs Nerv Syst2006，22，11： | 1 |
| 16 | Human DNA repair genes显示文摘 | Wood RD Mitchell M Sgouros J | | 0，，5507： | 1 |
| 17 | Complications of endoscopic third ventriculostomy: A review显示文摘 | Bouras T Sgouros S | 2011 | J Neurosurg Pediatric2011，7，6： | 1 |
| 18 | Brain tissue oxygenation changes in children during the first 24h following head injury显示文摘 | Ushewokunze S Sgouros S | 2009 | Childs Nerv Syst2009，25，3： | 1 |
| 19 | Complications of endoscopic third ventriculostomy显示文摘 | Bouras T Sgouros S | 2011 | Neurosurg Pediatrics2011，7，6： | 1 |
| 20 | Posterior fossa volume in children with Chiari malformation Type I显示文摘 | Sgouros S Kountouri M Natarajan K | 2006 | J Neurosurg2006，105，2： | 1 |
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