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| 1 | Listening to Turkish classical music decreases patients’anxiety,pain,dissatisfaction and the dose of sedative and analgesic drugs during colonoscopy:A prospective randomized controlled trial显示文摘AIM: To determine whether listening to music decreases the requirement for dosages of sedative drugs, patients’ anxiety, pain and dissatisfaction feelings during colonoscopy and makes the procedure more comfortable and acceptable. METHODS: Patients undergoing elective colonoscopy between October 2005 and February 2006 were randomized into either listening to music (Group 1, n = 30) or not listening to music (Group 2, n = 30). Anxiolytic and analgesic drugs (intravenous midazolam and meperidine) were given according to the patients’ demand. Administered medications were monitored. We determined their levels of anxiety using the State-Trait Anxiety Inventory Test form. Patients’ satisfaction, pain, and willingness to undergo a repeated procedure were self-assessed using a visual analog scale.RESULTS: The mean dose of sedative and analgesic drugs used in group 1 (midazolam: 2.1 ± 1.4, meperidine: 18.1 ± 11.7) was smaller than group 2 (midazolam: 2.4 ± 1.0, meperidine: 20.6 ± 11.5), but without a significant difference (P > 0.05). The mean anxiety level in group 1 was lower than group 2 (36.7 ± 2.2 vs 251.0 ± 1.9, P < 0.001). The mean satisfaction score was higher in group 1 compared to group 2 (87.8 ± 3.1 vs 58.1 ± 3.4, P < 0.001). The mean pain score in group 1 was lower than group 2 (74.1 ± 4.7 vs 39.0 ± 3.9, P < 0.001).CONCLUSION: Listening to music during colonoscopy helps reduce the dose of sedative medications, as well as patients’ anxiety, pain, dissatisfaction during the procedure. Therefore, we believe that listening to music can play an adjunctive role to sedation in colonoscopy. It is a simple, inexpensive way to improve patients’ comfort during the procedure. | Nimet Ovayolu Ozlem Ucan Seda Pehlivan Yavuz Pehlivan Hakan Buyukhatipoglu M Cemil Savas Murat T Gulsen | 2006 | World Journal of Gastroenterology2006,12,46: | 10 |
| 2 | Leptin levels in the differential diagnosis between benign and malignant ascites显示文摘AIM: To evaluate the role of leptin levels in the differential diagnosis of ascites. METHODS: Ascitic leptin, TNFα and serum leptin levels were measured in 77 patients with ascites (35 with malignancies, 30 cirrhosis and 12 tuberculosis). Control serum samples were obtained from 20 healthy subjects. Leptin and TNFα levels were measured by ELISA. Body mass index (BMI) and percentage of body fat (BFM) by skin fold measurement were calculated for all patients and control groups. Peritoneal biopsy, ascites cytology and cultures or biochemical values were used for the diagnosis of patients. RESULTS: In patients with malignancies, the mean serum and ascites leptin levels and their ratios were significantly decreased compared to the other patient groups and controls. In tuberculosis peritonitis, ascitic fluid TNFα levels were significantly higher than malignant ascites and cirrhotic sterile ascites. BMI and BFM values did not distinguish between patients and controls. CONCLUSION: In patients with malignant ascites, levels of leptin and TNFα were significantly lower than in patients with tuberculous ascites. | Mehmet Buyukberber Mehmet Koruk M Cemil Savas Murat T Gulsen Yavuz Pehlivan Rukiye Deveci Alper Sevinc Serdar Gergerlioglu | 2007 | World Journal of Gastroenterology2007,13,3: | 7 |
| 3 | Therapeutic effect of caffeic acid phenethyl ester on cerulein-induced acute pancreatitis显示文摘AIM: To evaluate the therapeutic role of caffeic acid phenethyl ester (CAPE) in a rat model of ceruleaninduced acute pancreatitis (AP).METHODS: Seventy male Wistar albino rats were divided into seven groups. Acute edematous pancreatitis was induced by subcutaneous cerulein injection (20 μg/kg) four times at 1-h intervals. CAPE (30 mg/kg) was given by subcutaneous injection at the beginning (CAPE 1 group) and 12 h after the last cerulein injection (CAPE 2 group). Serum amylase, lipase, white blood cell count, and tumor necrosis factor (TNF)-α levels were measured, and pancreatic histopathology was assessed. RESULTS: In the AP group, amylase and lipase levels were found to be elevated and the histopathological evaluation showed massive edema and inflammation of the pancreas, with less fatty necrosis when compared with sham and control groups. Amylase and lipase levels and edema formation decreased signif icantly in the CAPE therapy groups (P < 0001); especially in the CAPE 2 group, edema was improved nearly completely (P = 0001). Inflammation and fatty necrosis were partially recovered by CAPE treatment. The pathologicalresults and amylase level in the placebo groups were similar to those in the AP group. White blood cell count and TNF-α concentration was nearly the same in the CAPE and placebo groups.CONCLUSION: CAPE may be useful agent in treatment of AP but more experimental and clinical studies are needed to support our observation of benef icial effects of CAPE before clinical usage of this agent. | Mehmet Buyukberber M Cemil Savas Cahit Bagci Mehmet Koruk Murat T Gulsen Ediz Tutar Tugba Bilgic Nurdan Ceylan | 2009 | World Journal of Gastroenterology2009,15,41: | 4 |
| 4 | Pentoxifylline improves blood flow to both testes in testicular torsion 显示文摘 | Savas C Dindar H Aras T | 2002 | Int Urol Nephrol2002,33,1: | 1 |
| 5 | Effect of cooling rate on the structure and mechanical properties of monotectoid zinc-aluminium alloys 显示文摘 | Savas T S Murphy S | 2003 | Journal of Materials Science and Technology2003,19,1: | 1 |
| 6 | Free insulin-like growth factor-1 and unilateral complete ureteral obstrustion in the rats显示文摘 | SEREL T A SAVAS C DELIBAS N | 2000 | Urology2000,56,65: | 1 |
| 7 | Docetaxel with or without estramustine phosphate,as first-line chemotherapy for hormone-refractory prostate cancer:results of a multicentre,randomized phase Ⅱ trial显示文摘 | Caffo O Sava T Comploj E | 2008 | BJU Int2008,102,9: | 1 |
| 8 | Phonon effects in molecular transistors:Quantal and classical treatment显示文摘 | Savas Berber D T | 2004 | Physical Reiew B2004,69,24: | 1 |
| 9 | Pentoxifylline improves blood flow to both testes in testicular torsion显示文摘 | Savas C Dindar H Aras T | 2002 | Int Urol Nephrol2002,33,1: | 1 |
| 10 | Microfluidic cell culture 显示文摘 | MATTHIAS M SAVAS T | 2014 | Current Opinion in Biotechnology2014,25,: | 1 |
| 11 | Characteristics of soil actinomycetes from Antarctica显示文摘 | Penka M Sava T Nadezhda D et at | 2000 | J Cult Collect2000,3,: | 1 |
| 12 | Application of fluidized carrier to bacterial sulphate reduction in industrial wastewaters purification 显示文摘 | VLADISLAV S SAVA T | 1992 | Biotechnology Techniques1992,6,1: | 1 |
| 13 | Clinical coiof hepatits B virus- infection in renal allograft recipients显示文摘 | Savas N Colak T Selcuk H | 2007 | Dig Dis Sci2007,52,12: | 1 |
| 14 | Optimal Reverse Channel Structure for Consumer Product Returns 显示文摘 | SCHULMAN J D COUGHLAN A T SAVAS KAN R C | 2010 | Marketing Science2010,,6: | 1 |
| 15 | Fabrication of patterned media for high density magnetic storage显示文摘 | Ross C A Smith Henry I Savas T | 1999 | J Vac Sci Technol B1999,17,3: | 1 |
| 16 | Fabrication ofpat- terned media for high density magnetic storage显示文摘 | Ross C A Smith H I Savas T | 1999 | J Vac Sei Technol1999,17,6: | 1 |
| 17 | Trigeminal nerve: MRI anatomy and ease presentation of trigeminal neuralgia due to arterial compression 显示文摘 | Sava A Furnie C Petreu T | 2012 | Rom J Morphol Embryol2012,53,4: | 1 |
| 18 | Differences in AMPA andkainate receptor interactomes facilitate identification of AMPA receptor auxiliary subunit GSG1L显示文摘 | Shanks NF Savas JN Maruo T | 2012 | Cell Rep2012,1,6: | 1 |
| 19 | Interference lithography显示文摘 | CARTER J M FLEMING R C SAVAS T A | 2003 | MTL Annual Report2003,,: | 1 |
| 20 | Imaging of extranodal lymphoma with PET/CT显示文摘 | ILICA A T KOCACELEBI K SAVAS R | 2011 | Clin Nucl Med2011,36,10: | 1 |