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| 1 | Deep sedation during gastrointestinal endoscopy: Propofol-fentanyl and midazolam-fentanyl regimens显示文摘AIM: To compare deep sedation with propofol-fentanyl and midazolam-fentanyl regimens during upper gastrointestinal endoscopy. METHODS: After obtaining approval of the research ethics committee and informed consent, 200 patients were evaluated and referred for upper gastrointestinal endoscopy. Patients were randomized to receive propofol-fentanyl or midazolam-fentanyl (n = 100/group).We assessed the level of sedation using the observer's assessment of alertness/sedation (OAA/S) score and bispectral index (BIS). We evaluated patient and physician satisfaction, as well as the recovery time and complication rates. The statistical analysis was performed using SPSS statistical software and included the MannWhitney test, χ 2 test, measurement of analysis of variance, and the κ statistic. RESULTS: The times to induction of sedation, recovery, and discharge were shorter in the propofolfentanyl group than the midazolam-fentanyl group. According to the OAA/S score, deep sedation events occurred in 25% of the propofol-fentanyl group and 11% of the midazolam-fentanyl group (P = 0.014). Additionally, deep sedation events occurred in 19% of the propofol-fentanyl group and 7% of the midazolamfentanyl group according to the BIS scale (P = 0.039). There was good concordance between the OAA/S score and BIS for both groups (κ = 0.71 and κ = 0.63, respectively). Oxygen supplementation was required in 42% of the propofol-fentanyl group and 26% of the midazolam-fentanyl group (P = 0.025). The mean time to recovery was 28.82 and 44.13 min in the propofolfentanyl and midazolam-fentanyl groups, respectively (P < 0.001). There were no severe complications in either group. Although patients were equally satisfied with both drug combinations, physicians were more satisfied with the propofol-fentanyl combination. CONCLUSION: Deep sedation occurred with propofolfentanyl and midazolam-fentanyl, but was more frequent in the former. Recovery was faster in the propofol-fentanyl group. | Marcos Eduardo Lera dos Santos Fauze Maluf-Filho Dalton Marques Chaves Sergio Eiji Matuguma Edson Ide Gustavo de Oliveira Luz Thiago Ferreira de Souza Fernanda C Simoes Pessorrusso Eduardo Guimares Hourneaux de Moura Paulo Sakai | 2013 | World Journal of Gastroenterology2013，19，22： | 16 |
| 2 | Effects of elevated [CO_2] on stem and root lodging among rice cultivars显示文摘Studies showed that elevated [CO2] would improve photosynthetic rates and enhance yields of rice;however,few studies have focused on the response of rice lodging,which is a major cause of cereal yield loss and quality reduction,under elevated [CO2].In this study,we examined the effects of elevated [CO2] on stem and root lodging using 4 rice cultivars(86Y8,japonica hybrid;LYP9,2-line indica hybrid;variety 9311,type of indica inbred rice,and SY63,3-line indica hybrid) grown under two [CO2] levels:400 and 680 μmol mol-1.Our results indicated that under elevated [CO2],the stem-lodging risk(SLR) of 9311 decreased,while in SY63 the SLR increased,86Y8 and LYP9 were not significantly affected;the risk of root lodging was reduced for all cultivars,because root biomass(instead of root number) and bending strength were increased significantly,and then the increase of anti-lodging ability is far higher than that of self-weight mass moment for all cultivars.These findings suggested that higher [CO2] can enhance the risk of stem-lodging for cultivars with strong-[CO2]-responses,but may not aggravate the root lodging for all rice cultivars. | ZHU ChunWu CHENG WeiGuo SAKAI Hidemitsu OIKAWA Shimpei LAZA Rebecca C USUI Yasuhiro HASEGAWA Toshihiro | 2013 | Chinese Science Bulletin2013，58，15： | 4 |
| 3 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 4 | Biocompatibility of subsieve-size capsules versus conventional-size microcapsules 显示文摘 | Sakai S Mu C Kawabata K | 2006 | J Biomed Mater Res A2006，78，2： | 1 |
| 5 | Simultaneous removal of SOx and NOx using slaked lime at low temperature显示文摘 | SAKAI M SU C SASAOKA E | 2002 | Industrial & Engineering Chemistry Research2002，41，20： | 1 |
| 6 | Correction of recurrent inverted nipples with the Sakai method 显示文摘 | Taneda H Sakai S Kamei C | 2013 | Ann Plast Surg2013，71，2： | 1 |
| 7 | Regulation of GFRa-1 and GFRa-2 mRNAs in rat brain by electroconvulsive seizure显示文摘 | HEN A C H EISCH A J SAKAI N | 2001 | Synapse2001，39，： | 1 |
| 8 | The activities of myco- toxins derived from Fusarium and related substances in a short-term transformation assay using v-Ha-ras-transfected BALB/3T3 cells (Bhas 42 cells) 显示文摘 | Sakai A Suzuki C Masui Y | 2007 | Mutation Research2007，630，12： | 1 |
| 9 | The effects of pulsed streamer-like discharge on cyanobacteria cells显示文摘 | LI Z SAKAI S YAMADA C | 2006 | IEEE Transactions on Plasma Science2006，34，5： | 1 |
| 10 | The dy-namic measurement of surface charge distribution de-posited from partial discharge in air by pockels effecttechnique显示文摘 | ZHU Y C TAKADA T SAKAI K | 1996 | Journal of Physics:D Applied Phys-ics1996，29，11： | 1 |
| 11 | Pseudobulb injected growth regulators as aids for year around production of Hawaiian Dendrobium orchid cut flowers 显示文摘 | SAKAI W S ADAMS C BRAUN G | 2000 | Acta Horticuhurae2000，514，2： | 1 |
| 12 | Direct comparison of brain natriuretie peptide(BNP)and N-terminal pro-BNP secre-tion andextent of coronary artery stenosis in patients with stable coronary artery disease显示文摘 | Sakai H Tsutamoto T Ishikawa C et a1 | 2007 | Circ J2007，71，4： | 1 |
| 13 | Inhibitory effect of magnesium 1-ascorbyl-2-phosphate (VC-PMG) on melanogenesis in vitro and in vivo显示文摘 | Kameyama K Sakai C Kondoh S | 1996 | Journal of the American Academy of Dermatology1996，34，1： | 1 |
| 14 | Takayasu arteritis显示文摘 | Sakai C Kawasaki T Sakaguchi T | | 0，，： | 1 |
| 15 | Correction of recurrent inverted nip- pies with the Sakai method显示文摘 | Taneda H Sakai S Kamei C | 2013 | Ann Plast Surg2013，71，2： | 1 |
| 16 | Mutations in CBL occur frequently in juvenile myelomonocytic leukemia显示文摘 | Lob ML Sakai DS Flotho C | | 0，，： | 1 |
| 17 | Virulence-associated genetic regions comprising 31 kilobases of the 230- kilobase plasmid in Shigella flexneri 2a 显示文摘 | Sasakawa C Kamata K Sakai T | 1988 | J Bacteriol1988，170，6： | 1 |
| 18 | Cryopreservation of in vitro-grown apical meristems of wasabi (Wasabi japonica) by encapsulationvitrification method显示文摘 | Matsumoto T Sakai A Takahashi C | 1995 | Cryo-Letters1995，16，4： | 1 |
| 19 | Cyclic tests on steel and concrete-filled tube frames with slit walls 显示文摘 | Hitaka T Matsui C Sakai J | 2007 | Earthquake Engineering and Structural Dynamics2007，36，6： | 1 |
| 20 | Mutations in CBL occur frequently in juvenile myelomonocytic leukemia显示文摘 | Loh ML Sakai DS Flotho C | 2009 | Blood2009，114，9： | 1 |
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