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1Incidental congenital coronary artery vascular fistulas in adults:Evaluation with adenosine-13N-ammonia PET-CT显示文摘AIM To assess the functionality of congenital coronary artery fistulas(CAFs) using adenosine stress ^(13)N-ammonia positron emission tomography computed tomography(PET-CT).METHODS Congenital CAFs were incidentally detected during coronary angiography(CAG) procedures in 11 adult patients(six males and five females) with a mean age of 64.3 years(range 41-81). Patients were collected from three institutes in the Netherlands. The characteristics of the fistulas(origin, pathway and termination), multiplicity of the origins and pathways of the fistulous vessels were assessed by CAG. Five patients underwent adenosine pharmacologic stress ^(13)N-ammonia PET-CT to assess myocardial perfusion and the functional behavior of the fistula. RESULTS Eleven patients with 12 CAFs, 10 unilateral and one bilateral, originating from the left anterior descending coronary artery(n = 8), right coronary artery(n = 2) and circumflex(n = 2). All fistulas were of the vascular type, terminating into either the pulmonary artery(n = 11) or coronary sinus(n = 1). The CAG delineated the characteristics of the fistula(origin, pathway and termination). Multiplicity of the origins and pathways of the fistulous vessels were common in most fistulas(8/12, 67% and 9/12, 75%, respectively). Multiplicity was common among the different fistula components(23/36, 64%). Adenosine pharmacologic stress ^(13)N-ammonia PET-CT revealed normal myocardial perfusion and ejection fraction in all but one patient, who showed a reduced ejection fraction.CONCLUSION PET-CT may be helpful for assessing the functional status of congenital CAFs in selected patients regarding clinical decision-making. Studies with a larger patient series are warranted.Salah AM Said Aly Agool Arno HM Moons Mounir WZ Basalus Nils RL Wagenaar Rogier LG Nijhuis Jutta M Schroeder-Tanka Riemer HJA Slart 2018World Journal of Cardiology2018,10,10:2
2Coronary-cameral fistulas in adults: Acquired types(second of two parts)显示文摘Acquired coronary artery fistulas(CCFs)are infrequently detected during conventional coronary angiography.To delineate the characteristics of congenital(first part)and acquired(second part)CCFs in adults,a PubMed search was conducted for papers dealing with congenital or acquired CCFs.None of the publications describing patients with coronary-vascular fistulas were included.Papers dealing with pediatric subjects were excluded.From the world literature,a total of 243adult patients were selected who had congenital(n=159/243,65%)and acquired(n=84/243,35%)CCFs.Among the acquired types(n=72,85.7%)were traumatic(iatrogenic(n=65/72,90%),accidental(n=7/72,10%)and(n=12,14.3%)spontaneously developing in relation to severe coronary atherosclerosis or myocardial infarction.A high incidence of spontaneousresolution of iatrogenic CCFs resulting from endomyocardial biopsy or following post-septal myectomy was reported.Spontaneous CCFs associated with myocardial ischemia or infarction resolved completely in 8%of the subjects.Early surgical intervention was the treatment of choice in acquired traumatic accidental CCFs.The congenital types are addressed in a previous issue of this journal(first part).In this review(second of two parts,partⅡ),we describe the acquired coronarycameral fistulas.Salah AM Said Rikke HM Schiphorst Richard Derksen Lodewijk J Wagenaar 2013World Journal of Cardiology2013,5,12:2
3Biotin uptake by human proximal tubular epithelial cells: cellular and molecular aspects 显示文摘BALAMURUGAN K VAZIRI ND SAID HM 2005Am J Physiol Renal Physiol2005,288,4:1
4Congenitally Corrected Transposition of Great Arteries Surgical Options for the Failing Right Ventricle and/or Severe Tricuspid Regurgitation显示文摘Said SM Burkhart HM Schaff HV 2011World J Pediatr Congenit Heart Surg2011,2,1:1
5High-frequency oscillatory ventilation reduces lung inflammation: a large animal 24h model of respiratory distress 显示文摘Muellenbach RM Kredel M Said HM 2007Intens Care Med2007,33,8:1
6High - frequen- cy oscillatory ventilation reduces lung inflammation: a large animal 24 h model of respiratory distress 显示文摘Muellenbach RM Kredel M Said HM 2007Intens Care Med2007,33,8:1
7A carrier-mediated mechanism for pyridoxine uptake by human intestinal epithelial Caco-2 cells:regulation by a PKA-mediated pathway显示文摘Said HM Ortiz A Ma TY 2003Am J Physiol Cell Physiol2003,285,5:1
8Surgical management of congenital (non-Ebstein) tricuspid valve regurgitation 显示文摘Said SM Burkhart HM Dearani JA 2012Semin Thorac Cardio- vase Surg Pediatr Card Surg Annu2012,15,1:1
9Gressner, Y-box protein-1 is the crucial mediator of antifibrotic interferon-y effects 显示文摘Steven D Said HM Axel M 2006J Biol Chem2006,281,3:1
10High-frequency oscillatory ventilation reduces lung inflammation : a large- animal 24 h model of respiratory distress 显示文摘Muellenbach RM Kredel M Said HM 2007Intensive Care Med2007,33,8:1
11Immunohistochemical detection of osteopontin in advanced head-and-neck cancer:prognostic role and correlation with oxygen electrode measurements,hypoxia-inducible-factor-1alpha-related markers and hemoglobin levels显示文摘Bache M Reddemann R Said HM 0,,05:1
12Expression patterns of the hypoxia-related genes osteopontin, CA9, erythropoie- tin, VEGF and HIF-lalpha in human glioma in vitro and in vivo显示文摘Said HM Hagemann C Staab A 2007Radiother Oncol2007,83,3:1
13Recent advances in carrier-mediated intestinal absorption of water-soluble vitamins 显示文摘Said HM 2004Ann Rev Physiol2004,66,:1
14Expression patterns of the hypoxia-related genes osteopontin, CA9, erythropoietin, VEGF and HIF-lalpha in human glioma in vitro and in vivo显示文摘Said HM Hagemann C Staab A 2007Radiother Oncol2007,83,3:1
15Transport of glycyl-L-Proline in intestinal brush border membrane vesicles of the suckling rat: characteristics and maturation 显示文摘Said HM Ghishan FK Resha R 1988Biochem BiophysActa1988,941,5:1
16Immunohistochemical detection of osteopontin in advanced head-and-neck cancer:p-rognostic role and correlation with oxygen electrode measurem-ents,hypoxia-inducible-factor-1α-related markers,and hemo-globin levels显示文摘Bache M Reddenann R Said HM 2006Int J Radia Oncol Biol Phys2006,66,5:1
17Expression patterns of the hypoxia-related genes osteopontin,CA9,erythropoietin,VEGF and HIF-1alpha in human glioma in vitro and in vivo显示文摘Said HM Hagemann C Staab A 2007Radiother Oncol2007,83,3:1
18Oxygen-dependent regulation of NDRG1 in human glioblastoma cells in vitro and in vivo显示文摘Said HM Stein S Hagemann C 2009Oncol Rep2009,21,1:1
19An endogenous carrier- mediated uptake system for folate in oocytes of Xenopus laevis 显示文摘Lo RS Said HM Unger TF 1991Proc Biol Sci1991,246,1316:1
20Effects of HIF-1 inhibition by chetomin on hypoxia-related transcription and radiosensitivity in HT 1080 human fibrosarcoma cells显示文摘Staab A Loeffler J Said HM Diehlmann D Katzer A Beyer M 2007BMC Cancer2007,7,:1
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