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| 1 | Drainage vs. non-drainage after cholecystectomy for acute cholecystitis:a retrospective study显示文摘Many surgeons practice prophylactic drainage after cholecystectomy without reliable evidence,this study was conducted to answer the question whether to drain or not to drain after cholecystectomy for acute calculous cholecystitis.A retrospective review of all patients who had cholecystectomy for acute cholecystitis in Aseer Central Hospital,Abha,Saudi Arabia,was conducted from April 2010 to April 2012.Data were extracted from hospital case files.Preoperative data included clinical presentation,routine investigations and liver function tests.Operative data included excessive adhesions,bleeding,bile leak,and drain insertion.Complicated cases such as pericholecystic collections,mucocele and empyema were also reported.Patients who needed therapeutic drainage were excluded.Postoperative data included hospital stay,volume of drained fluid,time of drain removal,and drain site problems.The study included 103 patients allocated into two groups;group A(n = 38) for patients with operative drain insertion and group B(n = 65) for patients without drain insertion.The number of patients with preoperative diagnosis of acute non-complicated cholecystitis was significantly greater in group B(80%) than group A(36.8%)(P < 0.001).Operative time was significantly longer in group A.All patients who were converted from laparoscopic to open cholecystectomy were in group A.Multivariate analysis revealed that hospital stay was significantly(P < 0.001) longer in patients with preoperative complications.There was no added benefit for prophylactic drain insertion after cholecystectomy for acute calculous cholecystitis in non-complicated or in complicated cases. | Mohammed A Bawahab Walid M Abd El Maksoud Saeed A Alsareii Fahad S Al Amri Hala F Ali Abdul Rahman Nimeri Abdul Rahman M Al Amri Adel A Assiri Mohammed I Abdul Aziz | 2014 | The Journal of Biomedical Research2014，28，3： | 3 |
| 2 | Efficacy and safety of treatment of hepatitis C virus infection in renal transplant recipients显示文摘AIM: To assess the efficacy and safety of combinedpegylated interferon and ribavirin therapy in hepatitis C virus (HCV) infection in renal transplant recipients. METHODS: This is a retrospective chart review of post renal transplant patients who were positive for anti-HCV and HCV-RNA, and who have received treatment with combination of pegylated interferon and ribavirin between October 2003 and December 2008. Only patients with stable graft function and absence of evidence of cirrhosis and who received the therapy for continuous 48 wk were included. Nineteen patients (13 male and 6 female) were identified and included. The patient's complete blood count, liver and kidney prof ile, and cal- culated glomerular f iltration rate (GFR) were monitored every 6-8 wk while on treatment. HCV-RNA was tested at 12 wk for early virological response, at 48 wk for end of treatment response (ETR), and then retested at 24, and 48 wk after completion of therapy for sustained virological response (SVR). Liver biopsies were obtained before treatment from all patients and graft kidney biopsies were performed as required. RESULTS: Of the entire cohort, 9 patients (47.4%) showed an ETR and 8 had SVR (42.1%). Of the 8 patients with abnormal alanine aminotransferase (ALT) levels at baseline, 78.9% had their ALT normalized (including the virological non responders). ALT was normal in all responders at the end of therapy and at 24 wk post therapy (100%). Only one patient (5.3%) developed an increase in creatinine and decline in GFR from baseline towards the end of treatment. This patient's kidney biopsy revealed borderline rejection. There was no impact on response by HCV-genotype, initial HCV RNA load, age or sex of the patient or duration post transplant before commencement of therapy. All patients tolerated treatment in the same way as non-transplant with no unusual or increased occurrence of side effects. CONCLUSION: The combination of pegylated interferon and ribavirin is effective in suppressing HCV-RNA,with a low risk of graft rejection or failure in HCV infected renal transplant recipients. | Abdulrahman A Aljumah Mohamed A Saeed Ahmed I Al Flaiw Ibrahim H Al Traif Abduljaleel M Al Alwan Salem H Al Qurashi Ghormallah A Al Ghamdi Fayez F Al Hejaili Mohammed A Al Balwi Abdulla A Al Sayyari | 2012 | World Journal of Gastroenterology2012，18，1： | 2 |
| 3 | Symptomatic meck- el's diverticulum in children:a 16 year review显示文摘 | Menezes M Tareen F Saeed A | 2008 | Pediatr Surg Int2008，24，5： | 1 |
| 4 | Ichnaea a low overhead ro- bust WLAN device free passive localization system 显示文摘 | Saeed A Kosba AE Yousse M f | 2013 | IEEE J Sel Topics Signal Process2013，8，1： | 1 |
| 5 | Novel,rapid assay for measuring entry of diverse enveloped viruses,including HIV and rabies显示文摘 | Saeed M F Kolokoltsov A A Davey R A | 2006 | J Virol Methods2006，135，2： | 1 |
| 6 | Cellular entry of ebola virus involves uptake by amacropinocytosis-like mechanism and subsequenttrafficking through early and late endosomes 显示文摘 | SAEED M F KOLOKOLTSOV A A ALBRECHT T | 2010 | PLoS Pathog2010，6，00： | 1 |
| 7 | Development of somaelones in sugarcane genotype BF - 162 and assessment of variability by random amplified polyrnorphic DNA (RAPD) and simple sequence repeats (SSR) markers in selected red rot resistant somaelones 显示文摘 | Shahid M T H Khan F A Saeed A Aslam M Rasul F | 2012 | African Journal of Bioteehnology2012，11，15： | 1 |
| 8 | Peripartum hysterectomy:a ten-year experience at a tertiary care hospital in a developing counlry显示文摘 | Saeed F Khatid R Khan M | 2010 | Trop Doer2010，40，1： | 1 |
| 9 | Progno- sis in pediatric idiopathic pulmonary hemosiderosis 显示文摘 | Saeed M M Woo M S Mac Laughlin E F | 1999 | Chest1999，116，3： | 1 |
| 10 | Inhibition of catechol-O-methyltransferase increases estrogen-DNA adduct formation显示文摘 | Zahid M Saeed M Lu F | | 0，，11： | 1 |
| 11 | Arabinoxylans and Arabinogalactans: A Comprehensive Treatise显示文摘 | Saeed F Pasha I Anjum F M | 2011 | Critical Reviews in Food Science and Nutrition2011，，51： | 1 |
| 12 | Anion recognition and sensing by a new macrocyclic dinuclear copper (Ⅱ ) complex: a selective receptor for iodide显示文摘 | MENDY J S SAEED M A FRONCZEK F R | 2010 | Inorg Chem2010，49，： | 1 |
| 13 | Phylogeny of the Simbu se-rogroup of the genus Bunyavirus显示文摘 | Saeed M F Li L Wang H | 2001 | J Gen Virol2001，82，9： | 1 |
| 14 | Conceptual reactor design for the methanol-to-olefins process on SAPO-34显示文摘 | Saeed M Alwahabi Gilbert F Froment | 2004 | Ind Eng Chem Res2004，43，： | 1 |
| 15 | Travassos da Rosa A, Li L, Shope R E, Tesh R B, Barrett A D Jatobal virus is a reassortant containing the small RNA of Oropouche virus显示文摘 | Saeed M F Wang H Suderman M | 2001 | Virus Res2001，77，： | 1 |
| 16 | Prognosis in pediatric idiopathic pulmonary hemosiderosis 显示文摘 | SAEED M M WOO M S MACLAUGHLIN E F | 1999 | Chest1999，116，3： | 1 |
| 17 | Reperfused myocardial infarction as seen with use of necrosis specific versus standard extracellular MR contrast media in rats显示文摘 | Saeed M Bremerich J Wendland M F Wyttenbach R Weinmann H J H iggins C B | 1999 | Radiology1999，213，： | 1 |
| 18 | Iquitos virus:a novel reassortant Orthobunyavirus associated with human ill-ness in Peru显示文摘 | Aguilar P V Barrett A D Saeed M F | 2011 | PLoS Negl Trop Dis2011，5，9： | 1 |
| 19 | Influence of TiO2 nanoparticle filler on the properties of PET and PLA nanocomposites显示文摘 | MEHDI F SAEED D MOHAMMAD M | 2012 | Polymer(Korea)2012，36，6： | 1 |
| 20 | Occlusive and reperfused myocardial infacts: MR imaging differentiation with nonionic Gd-DTPA-BAM 显示文摘 | Masui T Saeed M Wendland M F | 1991 | Radiology1991，181，： | 1 |
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