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| 1 | MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer显示文摘Despite tremendous efforts from scientists and clinicians worldwide, pancreatic adenocarcinoma(PDAC) remains a deadly disease due to the lack of early diagnostic tools and reliable therapeutic approaches. Consequently, a majority of patients(80%) display an advanced disease that results in a low resection rate leading to an overall median survival of less than 6 months. Accordingly, robust markers for the early diagnosis and prognosis of pancreatic cancer, or markers indicative of survival and/or metastatic disease are des-perately needed to help alleviate the dismal prognosis of this cancer. In addition, the discovery of new therapeutic targets is mandatory to design effective treatments. In this review, we will highlight the translational studies demonstrating that microRNAs may soon translate into clinical applications as long-awaited screening tools and therapeutic targets for PDAC. | Marion Gayral Sébastien Jo Naima Hanoun Alix Vignolle-Vidoni Hubert Lulka Yannick Delpu Aline Meulle Marlène Dufresne Marine Humeau Maёl Chalret du Rieu Barbara Bournet Janick Sèlves Rosine Guimbaud Nicolas Carrère Louis Buscail Jérome Torrisani Pierre Cordelier | 2014 | World Journal of Gastroenterology2014，20，32： | 4 |
| 2 | Effect of chemical treatments on technical fibres of flax:effects on water sorption and mechanical properties显示文摘 | Alix S Philippe E Bedassok A | 2012 | Carbohydrate Polymers2012，87，1： | 1 |
| 3 | IgE and IgG4 antibody responses to Aedes saliva in African children 显示文摘 | Remoue F Alix E Comelie S | 2007 | Acta Trop2007，104，23： | 1 |
| 4 | Cloning,sequence,and expression of the pantothenate permease (panF) gene of Escherichia coli显示文摘 | Jackowski S Alix J H | 1990 | Journal of Biological Chemistry1990，172，： | 1 |
| 5 | Pectinase treatments on technical fibres of flax: effects on water sorption and mechanical properties显示文摘 | Alix S Lebrun L Marais S | 2012 | Carbohydrate Polymers2012，87，1： | 1 |
| 6 | Effect of chemicaltreatments on water orption and mechanical properties of flax fibres显示文摘 | ALIX S PHILIPPE E BESSADOK A | 2009 | Bioresour Technol2009，100，20： | 1 |
| 7 | Effect of Chemical Treatments on Water Sorption and Mechanical Properties of Flax Fibres 显示文摘 | Alix S Philippe E Bessadok A | 2009 | Bioresource Technology2009，100，20： | 1 |
| 8 | Effect of chemical treatments on water sorption and mechanical properties of flax fibres 显示文摘 | Alix S Philippe E Bessadok A | 2009 | Bioresource Technology2009，100，11： | 1 |
| 9 | Cancer mi- crometastases 显示文摘 | Pantel K Alix - Panabieres C Riethdorf S | 2009 | Nat Rev Clin Oncol2009，6，6： | 1 |
| 10 | Pectinase treatments on technical fibres of flax:Effects on water sorption and mechanical properties显示文摘 | S Alix L Lebrun S Marais | 2012 | Carbohydrate Polymers2012，87，1： | 1 |
| 11 | Circulating tumor cells and bone marrow micrometastasis 显示文摘 | Alix - Panabieres C Riethdorf S Pantel K | 2008 | Clin Cancer Res2008，14，16： | 1 |
| 12 | Structure of the tetraspanin main extracellular domain显示文摘 | MICHEL S ALIX D CECILE L G | 2001 | J Biol Chem2001，276，40： | 1 |
| 13 | Effect of Chemi- cal Treatments on Water Sorption and Mechanical Pro- perties of Flax Fibres 显示文摘 | Alix S Philippe E Bessadok A | 2009 | Bioresource Technology2009，100，20： | 1 |
| 14 | Circulating tumor cells and bone marrow micrometastasis显示文摘 | Alix Panabieres C Riethdorf S Pantel K | 2008 | Clin Cancer Res2008，14，16： | 1 |
| 15 | Peptic ulcerdisease and the risk of bladder cancer in a prospective study of male health professionals显示文摘 | MICHAUD D S MYSLIWIEC P A ALIX)ORI W | 2004 | Cancer Epidem 15iomar2004，，13： | 1 |
| 16 | CVD diamond films:from growth to applications显示文摘 | ALIX G KHALED H FRANCOIS S | 2001 | Current Applied Physics2001，1，6： | 1 |
| 17 | Pressure impact of autoclave treatment on water sorption and pectin composition of flax cellulosic-fibres显示文摘 | Alix S Colasse L Morvan C | 2014 | Carbohydrate Polymers2014，102，： | 1 |
| 18 | Hygrothermal/UV Aging Effect on Visual Aspect and Mechanical Properties of Non-Woven Natural-Fiber Composites显示文摘This work aims at studying the effect of hygrothermal and UV cyclic aging on the tensile properties and esthetic characteristics of non-woven composites.The composite materials were thermo-compressed from non-woven mats made up of PP and flax or kenaf fibers.This works included evaluating the change in color appearance and analyzing the variations in tensile properties and damage mechanisms,depending on the aging time.The presence of the UV protection film on the composite surface showed its effectiveness against aging.From visual observations and measurement of colorimetric parameters,it has been proved effective in the reduction of the bleaching and yellowing of the composites.As regards the tensile tests,the UV protection film enabled to stabilize the Young’s modulus after 1-week aging for Kenaf/PP and after 3-weeks for Flax/PP.After 4-weeks aging,it halved the number of acoustic emission events related to interfacial decohesion and fiber slippage/pull out for Flax/PP and Kenaf/PP composites. | Daniel Scida Sébastien Alix Stéphane Buet El Hadi Saidane François Courmont Karim Behlouli Rezak Ayad | 2019 | Journal of Renewable Materials2019，7，9： | 0 |
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