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| 1 | Fluid resuscitation in acute pancreatitis: Normal saline or lactated Ringer's solution?显示文摘AIM: To investigate whether administration of Ringer's solution(RL) could have an impact on the outcome of acute pancreatitis(AP).METHODS: We conducted a retrospective study on 103 patients [68 men and 35 women,mean age 51.2 years(range,19-92 years)] hospitalized between 2011 and 2012. All patients admitted to the Department of Gastroenterology of the Central Clinical Hospital of the Ministry of Interior(Poland) with a diagnosis of AP who had disease onset within 48 h of presentation were included in this study. Based on the presence of persistent organ failure(longer than 48 h) as a criterion for the diagnosis of severe AP(SAP) and the presence of local complications [diagnosis of moderately severe AP(MSAP)],patients were classified into 3 groups: mild AP(MAP),MSAP and SAP. Data were compared between the groups in terms of severity(using the revised Atlanta criteria) and outcome. Patients were stratified into 2 groups based on the type of fluid resuscitation: the 1-RL group who underwent standard fluid resuscitation with a RL 1000 m L solution or the 2-NS group who underwent standard fluid resuscitation with 1000 m L normal saline(NS). All patients from both groups received an additional 5% glucose solution(1000-1500 m L) and a multi-electrolyte solution(500-1000 m L).RESULTS: We observed 64(62.1%) patients with MAP,26(25.24%) patients with MSAP and 13(12.62%) patients with SAP. No significant difference in the distribution of AP severity between the two groups was found. In the 1-RL group,we identified 22(55.5%) MAP,10(25.5%) MSAP and 8(20.0%) SAP patients,compared with 42(66.7%) MAP,16(24.4%) MSAP and 5(7.9%) SAP cases in the 2-NS group(P = 0.187). The volumes of fluid administered during the initial 72-h period of hospitalization were similar among the patients from both the 1-RL and 2-NS groups(mean 3400 m L vs 3000 m L,respectively). No significant differences between the 1-RL and 2-NS groups were found in confirmed pancreatic necrosis [10 patients(25%) vs 12 patients(19%),respectively,P = 0.637]. There were no statistically significant differences between the 1-RL and 2-NS groups in the percentage of patients who required enteral nutrition(23 patients vs 17 patients,respectively,P = 0.534). Logistic regression analysis confirmed these findings(OR = 1.344,95%CI: 0.595-3.035,P = 0.477). There were no significant differences between the 1-RL and 2-NS groups in mortality and the duration of hospital stay(median of 9 d for both groups,P = 0.776).CONCLUSION: Our study failed to find any evidence that the administration of RL in the first days of AP leads to improved clinical outcomes. | Michal Lipinski Alicja Rydzewska-Rosolowska Andrzej Rydzewski Grazyna Rydzewska | 2015 | World Journal of Gastroenterology2015，21，31： | 21 |
| 2 | N-acetylcysteine does not prevent post-endoscopic retrograde cholangiopancreatography hyperamylasemia and acute pancreatitis显示文摘瞄准:尖锐胰腺炎(AP ) 是最普通、经常严重的复杂并发症内视镜后退 cholangiopancreatography (ERCP ) 。在尖锐胰腺炎的致病的早步可能是毛状的内皮损害由导出氧的自由基调停了。N-acetylcysteine - 自由基 scavenger 可能在阻止尖锐胰腺炎和它是的 post-ERCP 是潜在地有效的也知道那个 N-acetylcysteine (ACC ) 罐头在 AP 的试验性的模型减少疾病的严厉。方法:106 个病人随机被分配到二个组。55 个病人被给 N-acetylcysteine (口头上地,在 ERCP 和 600 mg 前的 24 和 12 h 被给 iv 的二 600 mg 剂量,两次为在 ERCP 以后的二天的一天) 。控制组由被给 iv 的 51 个病人组成了。等渗盐两次为在 ERCP 以后的二天的一天。浆液和尿淀粉酶活动在过程以后在 ERCP 和 8 和 24 h 前被测量。主要结果参数是尖锐胰腺炎和第二等的结果参数是的 post-ERCP 在浆液和尿淀粉酶活动的组之间的差别。结果:处于在二个组之间的 post-ERCP 胰腺炎的率没有有效差量(10 病人外套, 4 在 ACC 组织, 6 在控制组织) 。也在在 ACC 组和控制组之间的基线和 post-ERCP 浆液和尿淀粉酶活动没有有效差量。结论:N-acetylcysteine 没能在 post-ERCP 胰腺炎上,以及在浆液和尿淀粉酶活动上表明任何重要预防效果。 | Janusz Milewski Grazyna Rydzewska Malgorzata Degowska Maciej Kierzkiewicz Andrzej Rydzewski | 2006 | World Journal of Gastroenterology2006，12，23： | 10 |
| 3 | Factors associated with irritable bowel syndrome symptoms in hemodialysis patients显示文摘AIM: To investigate clinical characteristics associated with the presence of irritable bowel syndrome (IBS) symptoms in hemodialysis (HD) patients.METHODS: This was a cross-sectional study. A questionnaire based on the Bowel Disease Questionnaire that records gastrointestinal symptoms was given to 294 patients in 4 dialysis centers. A total of 196 (67%) subjects returned the survey. A multivariable logistic regression model was used to identify factors significantly associated with IBS symptoms. RESULTS: Symptoms compatible with IBS were present in 27 (13.8%) subjects and independently associated with low post-dialysis serum potassium [OR = 0.258, 95% CI (0.075-0.891), P = 0.032], paracetamol use [OR = 3.159, 95% CI (1.214-8.220), P = 0.018], and Kidney Disease Quality of Life (KDQOL) cognitive function score [OR = 0.977, 95% CI (0.956-0.999), P = 0.042]. Univariate regressions were also performed and the reported significance is for multivariate analysis. No association was detected for age, gender, depressed mood, smoking (present or past), body mass index, albumin level, Kt/V, sodium preor post-dialysis level, change in potassium level during HD, proton pump inhibitor or H2 blocker use, aspirin use, residual diuresis, hepatitis B or C infection, diabetes mellitus, marital status and education level. CONCLUSION: This study examined potential risk factors for symptoms compatible with IBS in HD patients and identified an association with paracetamol use, post-dialysis potassium level and KDQOL-cognitive function score. | Bartosz Fiderkiewicz Alicja Rydzewska-Rosoowska Micha Myliwiec Magdalena Birecka Bozenna Kaczanowska Grazyna Rydzewska Andrzej Rydzewski | 2011 | World Journal of Gastroenterology2011，17，15： | 5 |
| 4 | 显示文摘 | RYDZEWSKI B MATUSIAK M | 2005 | Otolaryngol Pol2005，59，： | 1 |
| 5 | Free fatty acids promote hepati clipotoxieity by stimulating TNF alpha expression via a lysose real pathway显示文摘 | Feldstein A E Werneburg N W Canbay A Guicciardi M E Bronk S F Rydzewski R | 2004 | Hepatology2004，40，： | 1 |
| 6 | Assessment of smell and taste in pati- ents with allergic rhinitis显示文摘 | Rydzewski B Pruszewicz A Sulkowski WJ | 2000 | Acta Otola- ryngol2000，120，： | 1 |
| 7 | Low protein diet causes a decrease in serum concentrations of leptin and tumour necrosis factor-alpha in patients with conservatively treated chronic renal failure显示文摘 | Kozlowska L Rosolowska-Huszcz D Rydzewski A | 2004 | Nephrology(Carhon)2004，9，5： | 1 |
| 8 | Angiotensin II stimulation of plasminogen activator inhibitor- 1 gene expression in astroglial cells from the brain显示文摘 | Rydzewski B Zelezna B Tang W | 1992 | Endocrinology1992，130，： | 1 |
| 9 | Adiponectin, resistin and leptin response to dietary intervention in diabetic nephropathy显示文摘 | Koz'towska L Rydzewski A Fiderkiewicz B | 2010 | J Ren Nutr2010，20，4： | 1 |
| 10 | Assesment of smell and taste in patients with allergic rhinitis显示文摘 | Rydzewski B Prttszewicz A Sulkowski WJ | 2000 | Acta Otolaryngol2000，120，2： | 1 |
| 11 | Adiponectin, resistin and leptin response to dietary intervention in diabetic nephropathy 显示文摘 | Koziowska L Rydzewski A Fiderkiewicz B | 2010 | Medline Journals2010，20，4： | 1 |
| 12 | Influence of low protein diet on nonthyroidal illness syndrome in chronic renal failure显示文摘 | Rosolowska-Huszcz D Kozlowska L Rydzewski A | 2005 | Endocrine2005，27，3： | 1 |
| 13 | Establishing a versatile fermentation and purification procedure for human proteins expressed in the yeasts Saccharomyces cerevisiae and Pichia pastoris for structural genomics显示文摘 | Prinz B Schultchen J Rydzewski R | | 0，，1： | 1 |
| 14 | Heart weights of white in man 20 to39 years of age:An analysis of autopsy cases显示文摘 | Rydzewski D | 1990 | Am J Forensic Med Pathol1990，11，3： | 1 |
| 15 | Early changes in serum creat-inine level and estimated glomerular filtration rate predict pancreatic necrosis andmortality in acute pancreatitis: Creatinine and eGFR in acute pancreatitis显示文摘 | Lipinski M Rydzewski A Rydzewska G | 2013 | Pancreatology2013，13，3： | 1 |
| 16 | Age related macular degeneration and presence of posterior vitreous detachment显示文摘 | Gawecki M Doroszkiewicz M Rydzewski J | | 0，，7： | 1 |
| 17 | Early changes in serum creat- inine level and estimated glomerular filtration rate predict pancreatic necrosis andmortality in acute pancreatitis: Creatinine and eGFR in a- cute pancreatitis 显示文摘 | Lipinski M Rydzewski A Rydzewska G | 2013 | Pancreatology2013，13，3： | 1 |
| 18 | The cellular and physiological actions of insulin in the central nervous system显示文摘 | Wozniak M Rydzewski B Baker SP | 1993 | Neurochem Int1993，22，1： | 1 |
| 19 | Iatrogenic foreign bodies found in the middle ear as a result of prosthetic management 显示文摘 | RYDZEWSKI B KROKOWICZ A | 2002 | Otolaryngol Pol2002，56，： | 1 |
| 20 | Assessment of smell and taste in patients with allergic rhinitis显示文摘 | RYDZEWSKI B PRUSZEWICZ A SULKOWSKI W J | 2000 | Aeta Otolaryngol2000，120，： | 1 |
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