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| 1 | Characterisation of human non-proliferative diabetic retinopathy using the fractal analysis显示文摘· AIM: To investigate and quantify changes in the branching patterns of the retina vascular network in diabetes using the fractal analysis method.·METHODS: This was a clinic-based prospective study of 172 participants managed at the Ophthalmological Clinic of Cluj-Napoca, Romania, between January 2012 and December 2013. A set of 172 segmented and skeletonized human retinal images, corresponding to both normal(24 images) and pathological(148 images)states of the retina were examined. An automatic unsupervised method for retinal vessel segmentation was applied before fractal analysis. The fractal analyses of the retinal digital images were performed using the fractal analysis software Image J. Statistical analyses were performed for these groups using Microsoft Office Excel2003 and Graph Pad In Stat software.·RESULTS: It was found that subtle changes in the vascular network geometry of the human retina are influenced by diabetic retinopathy(DR) and can be estimated using the fractal geometry. The average of fractal dimensions D for the normal images(segmented and skeletonized versions) is slightly lower than the corresponding values of mild non-proliferative DR(NPDR) images(segmented and skeletonized versions).The average of fractal dimensions D for the normal images(segmented and skeletonized versions) is higher than the corresponding values of moderate NPDR images(segmented and skeletonized versions). The lowestvalues were found for the corresponding values of severe NPDR images(segmented and skeletonized versions).· CONCLUSION: The fractal analysis of fundus photographs may be used for a more complete understanding of the early and basic pathophysiological mechanisms of diabetes. The architecture of the retinal microvasculature in diabetes can be quantitative quantified by means of the fractal dimension.Microvascular abnormalities on retinal imaging may elucidate early mechanistic pathways for microvascular complications and distinguish patients with DR from healthy individuals. | Stefan Tǎlu Dan Mihai Cǎlugǎru Carmen Alina Lupascu | 2015 | International Journal of Ophthalmology(English edition)2015，8，4： | 4 |
| 2 | Resistance switching for RRAM applications显示文摘Resistive random access memory (RRAM or ReRAM) is a non-volatile memory (NVM) technology that consumes minimal energy while offering sub-nanosecond switching. In addition, the data stability against high temperature and cycling wear is very robust, allowing new NVM applications in a variety of markets (au- tomotive, embedded, storage, RAM). Based on sudden conduction through oxide insulators, the characteristics of RRAM technology have still yet to be fully described. In this paper, we present our current understanding of this very promising technology. | CHEN Frederick T LEE HengYuan CHEN YuSheng HSU YenYa ZHANG LiJie CHEN PangShiu CHEN WeiSu GU PeiYi LIU WenHsing WANG SuMin TSAI ChenHan SHEU ShyhShyuan TSAI MingJinn HUANG Ru | 2011 | Science China(Information Sciences)2011，54，5： | 3 |
| 3 | Cincinnati pre- hospital stroke scale: reproducibility and validity 显示文摘 | Kothari RU Pancioli A Liu T | 1999 | Ann Emerg Med1999，33，4： | 1 |
| 4 | V203 modified LiFePO^C composite with improved electrochemical performance 显示文摘 | JIN Y YANG C P RU X H CHENG T CHEN C H | 2011 | J Power Sources2011，196，： | 1 |
| 5 | The ABCs of measuring intracerehral hemorrhage volumes显示文摘 | Kothari RU Brott T Broderick JP | 1996 | Stroke1996，27，8： | 1 |
| 6 | The ABCs of measuring intracerebral hemorrhage volumes 显示文摘 | Kothari RU Brott T Broderick JP | 1996 | Stroke1996，27，8： | 1 |
| 7 | The role of microRNAs in the regulation of cancer stem cells 显示文摘 | Takahashi RU Miyazaki H Ochiya T | 2014 | Front Genet2014，4，3： | 1 |
| 8 | The role of microRNAs in the regulation of cancer slem cells 显示文摘 | Takahashi RU Miyazaki H Ochiya T | 2014 | Front Genet2014，4，： | 1 |
| 9 | Two host cytoplasmic effectors are required for pathogenesis of Phytophthora sojae by suppression of host c]efenses 显示文摘 | Liu T Ye W Ru Y | 2011 | Plant Physio12011，155，： | 1 |
| 10 | Kinetic modeling of liquid- phase adsorption of reactive dyesand metallonson ehitosan显示文摘 | Feng C W Ru L T Juang R S | 2001 | Water Resource2001，35，3： | 1 |
| 11 | The ABCS of intracerebral hemorrhage volumes显示文摘 | Kothari RU Brott T Brodefick JP | | 0，，08： | 1 |
| 12 | Appearance of the levator animuscle subdivisions in magnetic resonance images 显示文摘 | Margulies RU Kearney R Stein T | 2006 | Obstetrics Gynecology2006，107，5： | 1 |
| 13 | Cincinnati Prehospital Stroke Scale:reproducibility and validity显示文摘 | Kothari RU Pancioli A Liu T | 1999 | Ann Emerg Med1999，33，4： | 1 |
| 14 | Role of microRNA in cancerdevelopment:biology and clinical applications显示文摘 | Takahashi RU Makiko O Ochiya T | 2012 | Nihon Geka Gak-kai Zasshi2012，113，2： | 1 |
| 15 | In vitro nasal drug delivery studies: comparison of derivatised, fibrillar and polymerized collagen matrix-based human nasal primary culture systems for nasal drug delivery studies显示文摘 | Agu RU Jorisscn M Willems T | 2001 | J Pharm Pharmacol2001，53，11： | 1 |
| 16 | Safety assessment of selected cyclodextrins-effect on ciliary activity using a human cell suspension culture model exhib-ting in vitro ciliogenesis显示文摘 | UCHENNA AGU RU JORISSEN M WILLEMS T | 2000 | Int J Pharm2000，193，2： | 1 |
| 17 | Sexual dysfunction in men with chroIfic prostafitis/ chronic pelvic pain syndrome: im- provement after trigger point release and paradoxical relaxation training显示文摘 | Anderson RU Wise D Sawyer T | 2006 | J Urol2006，176，4： | 1 |
| 18 | The mir-34 nicroRNA is required for the DNA damage response in vivo in Celegans and in vitro in human breast cancer cells显示文摘 | Kato M Paranjape T Muller RU | | 0，，25： | 1 |
| 19 | Spectrotemporal modulation transfer functions and speech intelligibility显示文摘 | Chi T Gao Y Guyton M C Ru P Shamma S | | 0，，05： | 1 |
| 20 | Frequency acqusition and tracking in high dynamic environments 显示文摘 | Su Yu T Wu Ru Chwen | 2000 | IEEE Transaction on Vehicular Technology2000，49，6： | 1 |
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