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| 1 | Effect of Liuweidihuang pill and Jinkuishenqi pill on inhibition of spontaneous breast carcinoma growth in mice显示文摘OBJECTIVE: To investigate the preventing and treating action of Liuweidihuang pill(LP) and Jinkuishenqi pill(JP) on spontaneous breast carcinoma in mice.METHODS: A model of spontaneous breast carcinoma was derived from 11.5-month-old female Kunming breeding mice following the delivery of several litters. The mice were randomly divided into five groups: model control group(C),Liuweidihuang pill high-dose group(LH; 4.6 g·kg1·d1),Liuweidihuang pill low-dose group(LL;2.3 g·kg1·d﹣1),Jinkuishenqi pill high-dose group(JH; 4.6 g·kg﹣1·d1) and Jinkuishenqi pill low-dose group(JL;2.3 g·kg﹣1·d﹣1). Cancer tissue volume was measured by water immersion. Histopathology was analyzed by hematoxylin and eosin staining. Vascular endothelial growth factor(VEGF),extracellular signal-regulated kinase(ERK) and cyclin D1 protein expression in cancer tissue was assayed by western blotting.RESULTS: Compared with the control group,cancer tissue volume and weight were lower in the LP and JP groups,and survival time was longer. The expression of VEGF,ERK and Cyclin D1 were inhibited in the LP and JP groups(P < 0.05),and cell differentiation was increased. Tumor weights and volumes and VEGF,ERK and Cyclin D1 expression in LL or LH were significantly lower than in JL and JH(P < 0.01).CONCLUSION: Both LP and JP could restrain cancer growth and promote cancer cell differentiation;moreover,LP was more effective than JP The likely mechanism of action was via inhibition of VEGF,ERK and cyclin D1. | Zheng Lixiang Liu Hongning Gong Yan Meng Xianming Jiang Runde Wang Xiaomin Wang Qiaofeng Wang Yue | 2015 | Journal of Traditional Chinese Medicine2015，35，4： | 8 |
| 2 | Emergency department rectal temperatures in over 10 years:A retrospective observational study显示文摘BACKGROUND:Fever in patients can provide an important clue to the etiology of a patient's symptoms.Non-invasive temperature sites(oral,axillary,temporal) may be insensitive due to a variety of factors.This has not been well studied in adult emergency department patients.To determine whether emergency department triage temperatures detected fever adequately when compared to a rectal temperature.METHODS:A retrospective chart review was made of 27 130 adult patients in a high volume,urban emergency department over an eight-year period who received first a non-rectal triage temperature and then a subsequent rectal temperature.RESULTS:The mean difference in temperatures between the initial temperature and the rectal temperature was 1.3 °F(P<0.001),with 25.9%of the patients having higher rectal temperatures >2°F,and 5.0%having higher rectal temperatures >4 °F.The mean difference among the patients who received oral,axillary,and temporal temperatures was 1.2 °F(PO.001),1.8 °F(PO.001),and 1.2 °F(P<0.001) respectively.About 18.1%of the patients were initially afebrile and found to be febrile by rectal temperature,with an average difference of 2.5 °F(P<0.001).These patients had a higher rate of admission(61.4%,P<0.005),and were more likely to be admitted to the hospital for a higher level of care,such as an intensive care unit,when compared with the full cohort(12.5%vs.5.8%,P<0.005).CONCLUSIONS:There are significant differences between rectal temperatures and noninvasive triage temperatures in this emergency department cohort.In almost one in five patients,fever was missed by triage temperature. | Graham A.Walker Daniel Runde Daniel M.Rolston Dan Wiener Jarone Lee | 2013 | World Journal of Emergency Medicine2013，4，2： | 2 |
| 3 | β-Thalassemia 显示文摘 | Rund D Rachmilewitz E | 2005 | N Engl J Med2005，353，11： | 1 |
| 4 | Nonobstetric emergencies in pregnancy, trauma and surgical conditions显示文摘 | Coleman MT Trianfo VA Rund DA | 1997 | Am J Obstet Gynecol1997，177，： | 1 |
| 5 | Therapy-related leukemia:clinical characteristics and analysis of new molecular risk factors in 96 adult patients显示文摘 | Rund D Krichevsky S Bar-Cohen S | 2005 | Leukemia2005，19，11： | 1 |
| 6 | Screening, prevention and treat- ment of viral hepatitis B reactivation in patients with haemato- logical malignaneies显示文摘 | Lalazar G Rund D Shouval D | 2007 | Br J Haematol2007，136，： | 1 |
| 7 | Screening,preventionand treatment of viral hepatitis B reactivation inpatients with haematological malignancies review显示文摘 | Lalazar G Rund D Shouval D | 2007 | Br J Haematol2007，136，5： | 1 |
| 8 | Vibration analysis for periodic diagnostic testing of circuit breakers显示文摘 | RUNDE M OTTESEN G E SKYBERG B | 1999 | IEEE Transactions on Power Delivery1999，11，4： | 1 |
| 9 | Attentional and executive dysfunctions in schizophrenia and depression: evidence from di-chotic listening performance显示文摘 | Hugdahl K Rund B R Lurid A et aI | 2003 | Biological Psychiatry2003，53，7： | 1 |
| 10 | Stocks and the weather: An exercise in data mining or yet another capital market anomaly? 显示文摘 | RUNDE K | 1997 | Empirical Economics1997，22，： | 1 |
| 11 | Solubility and sorption of redox-sensitive radionuclides (Np, Pu) in J-13 water from the Yucca Mountain site: comparison between experiment and theory显示文摘 | Runde W Conradson S D Efurd D W | 2002 | Appl Geochem2002，17，： | 1 |
| 12 | Hepatitis B infection and myeloma in developing coun- tries: therapeutic dilemmas 显示文摘 | Rund D | 2012 | Leuk Lymphoma2012，53，2： | 1 |
| 13 | Air-flow investigation for a medium-voltage load break switch显示文摘 | Aanensen N S Jonsson E Runde M | 2015 | IEEE Transactions on Power Delivery2015，30，1： | 1 |
| 14 | TANGENTS:THE MACHINE OF THE MIND显示文摘 | Nan Runde | | 0，，03： | 1 |
| 15 | Empirical relation- ships between air-load break switch parameters and interrupting performance显示文摘 | Stoa-Aanensen N S Runde M Jonsson E | 2016 | IEEE Transactions on Power Delivery2016，31，1： | 1 |
| 16 | Interruption in air for different medium-voltage switching duties显示文摘 | Jonsson E Runde M | 2015 | IEEE Transactions on Power Delivery2015，30，1： | 1 |
| 17 | More than a marine propeller – the flagellum of the probiotic Escherichia coli strain Nissle 1917 is the major adhesin mediating binding to human mucus显示文摘 | Anja Troge Wolfgang Scheppach Bjoern O. Schroeder Stefan A. Rund Klaus Heuner Jan Wehkamp Eduard F. Stange Tobias A. Oelschlaeger | 2012 | International Journal of Medical Microbiology . 2012 (7-8)2012，，7： | 1 |
| 18 | Brain activation measured with fMRI during a mental arithmetic task in schizophrenia and major depression显示文摘 | HUGDAHL K RUND B R LUND A | 2004 | Am J Psychiatry2004，161，： | 1 |
| 19 | Vibration Analysis for Periodic Diagnostic Testing of CircuitBreakers显示文摘 | RUNDE M OTIESEN G E SKYBERG B | 1996 | IEEE Transactions on Power Delivery1996，11，4： | 1 |
| 20 | Automatic continuity of derivations and epimorphisms显示文摘 | RUNDE V | 1991 | Pacific J Math1991，147，2： | 1 |
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