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| 1 | Preparation and characterization of nanoparticles from quaternized cyclodextrin-grafted chitosan associated with hyaluronic acid for cosmetics显示文摘Hyaluronic acid(HA, 20–50 kDa) is a hydrophilic macromolecule with anti-wrinkle effects and moisturizing properties. However, its high molecular weight prevents it from penetrating into the deeper layers of the skin and, thus, limits its benefits to topical effects. Thus, the objective of this study is to prepare nanoparticles of quaternized cyclodextrin-grafted chitosan(QCD-g-CS) associated with HA in different molar ratios of QCD-g-CS and HA. The conjugation of the carboxylic moieties of HA and the amides of QCD-g-CS was confirmed by Fourier-transform infrared spectroscopy. Thus, the system was optimized to create nanoparticles with a small size(235.63 ± 21.89 nm), narrow polydispersity index(0.13 ± 0.02), and zeta potential of 16.07 ± 0.65 m V. The association efficiency and loading efficiency were determined by ultra-performance liquid chromatography as 86.77 ± 0.69% and 10.85 ± 0.09%, respectively. The spherical morphology of the obtained nanoparticles was confirmed by transmission electron microscopy. Moreover, the in-vitro hydrating ability was significantly higher( P < 0.001) than that of bulk HA(3.29 ± 0.41 and 1.71 ± 0.05 g water/g sample, respectively). The safety of these nanoparticles at concentrations in the range of 0.01–0.10 mg/ml was confirmed via tests on human skin fibroblasts. Together, these results demonstrate that the developed nanoparticles are promising for future applications in cosmetics. | Sakhiran Sakulwech Nattaya Lourith Uracha Ruktanonchai Mayuree Kanlayavattanakul | 2018 | Asian Journal of Pharmaceutical Sciences2018，13，5： | 3 |
| 2 | Mucoadhesive property and biocompatibility of methylated N -aryl chitosan derivatives显示文摘 | Warayuth Sajomsang Uracha Rungsardthong Ruktanonchai Pattarapond Gonil Onanong Nuchuchua | 2009 | Carbohydrate Polymers2009，，4： | 1 |
| 3 | Encapsulation of citral isomers in extracted lemongrass oil with cyclodextrins:molecular modeling and physicochemical characterizations显示文摘 | RUNGSARDTHONG RUKTANONCHAI U Srinuanchai W Saesoo S | 2011 | Bioscience biotechnology and biochemistry2011，75，12： | 1 |
| 4 | Preparation and characterization of asiaticoside-loaded alginate films and their po- tential for use as effectual wound dressings显示文摘 | Sikareepaisan P Ruktanonchai U Supaphol P | 2011 | Carbohyd Polym2011，83，4： | 1 |
| 5 | Methytated N-aryl chitosan derivative/DNA complexnanoparticles for gene delivery: Synthesis and structure-activity relationships显示文摘 | SAJOMSANG W RUKTANONCHAI U GONIL P etal | 2009 | Carbohydrate Polymers2009，78，： | 1 |
| 6 | Incorporation methods for cholic acid chitosan-g-mPEG self-assembly micellar system containing camptothecin显示文摘 | Tanasait Ngawhirunpat Nanthida Wonglertnirant Praneet Opanasopit Uracha Ruktanonchai Rangrong Yoksan Kaewkarn Wasanasuk Suwabun Chirachanchai | 2009 | Colloids and Surfaces B: Biointerfaces2009，，1： | 1 |
| 7 | Electrospun cellulose acetate fiber mats contai- ning curcumin and release characteristic of the herbal substance显示文摘 | SUWANTONG O OPANASOPIT P RUKTANONCHAI U | 2007 | Polymer2007，48，26： | 1 |
| 8 | Process Optimization of Electrospun Silk Fibroin Fiber Mat for Accelerated Wound Healing 显示文摘 | Chutipakdeevong J Ruktanonchai U R | 2013 | Journal of Applied Polymer Science2013，130，5： | 1 |
| 9 | Quaterniza- tion of N-(3-pyridylmethyl) chitosan derivatives: effects of the de- gree of quaternization, molecular weight and ratio of N-methylpyri- dinium and N,N,N-trimethyl ammonium moieties on bactericidal ac- tivity显示文摘 | SAJOMSANG W RUKTANONCHAI U R GONI P | 2011 | Carbohydrate Polymers2011，82，： | 1 |
| 10 | Review:Development of SARS-CoV-2 immuno-enhanced COVID-19 vaccines with nano-platform显示文摘Vaccination is the most effective way to prevent coronavirus disease 2019(COVID-19).Vaccine development approaches consist of viral vector vaccines,DNA vaccine,RNA vaccine,live attenuated virus,and recombinant proteins,which elicit a specific immune response.The use of nanoparticles displaying antigen is one of the alternative approaches to conventional vaccines.This is due to the fact that nano-based vaccines are stable,able to target,form images,and offer an opportunity to enhance the immune responses.The diameters of ultrafine nanoparticles are in the range of 1–100 nm.The application of nanotechnology on vaccine design provides precise fabrication of nanomaterials with desirable properties and ability to eliminate undesirable features.To be successful,nanomaterials must be uptaken into the cell,especially into the target and able to modulate cellular functions at the subcellular levels.The advantages of nano-based vaccines are the ability to protect a cargo such as RNA,DNA,protein,or synthesis substance and have enhanced stability in a broad range of pH,ambient temperatures,and humidity for long-term storage.Moreover,nano-based vaccines can be engineered to overcome biological barriers such as nonspecific distribution in order to elicit functions in antigen presenting cells.In this review,we will summarize on the developing COVID-19 vaccine strategies and how the nanotechnology can enhance antigen presentation and strong immunogenicity using advanced technology in nanocarrier to deliver antigens.The discussion about their safe,effective,and affordable vaccines to immunize against COVID-19 will be highlighted. | Nawamin Sa-nguanmoo Katawut Namdee Mattaka Khongkow Uracha Ruktanonchai YongXiang Zhao Xing-Jie Liang | 2022 | Nano Research2022，15，3： | 1 |
| 11 | Physical characteristics of fish oil encapsulated by β-cyclodextrin using an aggregation method or polycaprolactone using an emulsion-diffusion method显示文摘 | CHOI M J RUKTANONCHAI U MIN S G | 2010 | Food Chemistry2010，119，4： | 1 |
| 12 | Morphological characterization of encapsulated fish oil with b-cyclodextrin and polycaprolactone 显示文摘 | Mi-Jung Choi Uracha Ruktanonchai Apinan Soottitantawat | 2009 | Food Research International2009，42，： | 1 |
| 13 | Physicochemical characteristics, cytotoxicity, and antioxidant ac- tivity of three lipid nanoparticulate formulations of alpha-lipoic acid显示文摘 | RUKTANONCHAI U BEJRAPHA P SAKULKHU U | 2009 | AAPS Pharm Sci Tech2009，10，1： | 1 |
| 14 | Physical characteristics of fish oil encapsulated by 显示文摘 | Choi M J Ruktanonchai U Mi S G | 2010 | Food Chem2010，119，： | 1 |
| 15 | Effect of lipid types on physicochemical characteris-tics, stability and antioxidant activity of gamma-o- ryzanol-loaded lipid nanoparticles显示文摘 | RUKTANONCHAI U SAKULKHU U BEJRAPHA P ct al | 2009 | Journal of Micro- encapsulation2009，26，： | 1 |
| 16 | Morphological characterization of encapsulated fish oil with P -cyclodextrin and polycaprolactone显示文摘 | CHOI M-J RUKTANONCHAI U SOOTTITANTAWATA | 2009 | Food research international2009，42，8： | 1 |
| 17 | In vitro biological evaluation of electrospun cellulose acetate fiber mats containing asiaticoside or curcumin显示文摘 | Orawan Suwantong Uracha Ruktanonchai Pitt Supaphol | | 0，，04： | 1 |
| 18 | Electrospun cellulose acetate fiber mats containing asiaticoside or Centella asiatica crude extract and the release characteristics of asiaticoside显示文摘 | Orawan Suwantong Uracha Ruktanonchai Pitt Supaphol | | 0，，19： | 1 |
| 19 | Physicalcharacteristics of fish oil encapsulated byβ-cyclodextrin using anaggregation method or polycaprolactone using an emulsion-diffusionmethod显示文摘 | CHOI M J RUKTANONCHAI U SANG-GI MIN S G | 2010 | Food Chemistry2010，119，4： | 1 |
| 20 | Novel quatern- ized chitosan containing β-cyclodextrin moiety: synthesis, char- acterization and antimicrobial activity显示文摘 | Gonil P Sajomsang W Ruktanonchai U R | 2011 | Carbohydrate Poly- mers2011，83，2： | 1 |
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