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| 1 | Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro显示文摘Dear Editor,In December 2019,a novel pneumonia caused by a previously unknown pathogen emerged in Wuhan,a city of 11 million people in central China.The initial cases were linked to exposures in a seafood market in Wuhan.1 As of January 27,2020,the Chinese authorities reported 2835 confirmed cases in China's Mainland,including 81 deaths.Additionally,19 confirmed cases were identified in Hong Kong,Macao and Taiwan,and 39 imported cases were identified in Thailand,Japan,South Korea,United States,Vietnam,Singapore,Nepal,France,Australia and Canada.The pathogen was soon identified as a novel coronavirus(2019-nCoV),which is closely related to sever acute respiratory syndrome CoV(SARS-CoV).2 Currently,there is no specific treatment against the new virus.Therefore,identifying effective antiviral agents to combat the disease is urgently needed. | Manli Wang Ruiyuan Cao Leike Zhang Xinglou Yang Jia Liu Mingyue Xu Zhengli Shi Zhihong Hu Wu Zhong Gengfu Xiao | 2020 | Cell Research2020,30,3: | 563 |
| 2 | Early screening and diagnosis strategies of pancreatic cancer:a comprehensive review显示文摘Pancreatic cancer is a highly malignant digestive system tumor with a poor prognosis.Most pancreatic cancer patients are diagnosed at an advanced stage or even metastasis due to its highly aggressive characteristics and lack of typical early symptoms.Thus,an early diagnosis of pancreatic cancer is crucial for improving its prognosis.Currently,screening is often applied in high-risk individuals to achieve the early diagnosis of pancreatic cancer.Fully understanding the risk factors of pancreatic cancer and pathogenesis could help us identify the high-risk population and achieve early diagnosis and timely treatment of pancreatic cancer.Notably,accumulating studies have been undertaken to improve the detection rate of different imaging methods and the diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration(EUS-FNA)which is the golden standard for pancreatic cancer diagnosis.In addition,there are currently no biomarkers with sufficient sensitivity and specificity for the diagnosis ofpancreatic cancer to be applied in the clinic. As the only serum biomarkerapproved by the United States Food and Drug Administration, carbohydrateantigen 19-9 (CA19-9) is not recommended to be used in the early screeningof pancreatic cancer because of its limited specificity. Recently, increasingnumbers of studies focused on the discovering of novel serum biomarkersand exploring their combination with CA19-9 in the detection of pancreaticcancer. Besides, the application of liquid biopsy involving circulating tumor cells(CTCs), circulating tumor DNA (ctDNA), microRNAs (miRNAs), and exosomesin blood and biomarkers in urine, and saliva in pancreatic cancer diagnosis aredrawing more and more attention. Furthermore, many innovative technologiessuch as artificial intelligence, computer-aided diagnosis system, metabolomicstechnology, ion mobility spectrometry (IMS) associated technologies, and novelnanomaterials have been tested for the early diagnosis of pancreatic cancer andhave shown promising prospects. Hence, this review aims to summarize therecent progress in the development of early screening and diagnostic methods,including imaging, pathological examination, serological examination, liquidbiopsy, as well as other potential diagnostic strategies for pancreatic cancer. | Jinshou Yang Ruiyuan Xu Chengcheng Wang Jiangdong Qiu Bo Ren Lei You | 2021 | Cancer Communications2021,41,12: | 23 |
| 3 | Application of autocorrelation method on ionospheric short--term forecasting in China显示文摘Adopting the autocorrelation method in the ionospheric short-term forecasting, we put for- ward a simple and practical forecasting method― the sectional autocorrelation method, that is, for pre- dictions of one hour to four hours ahead the auto- correlation coefficient of RDF with the “iteration” method is selected, for prediction of more than four hours ahead, the autocorrelation coefficient of f0F2 with the “at once” method is used. The prediction precisions have been quantitatively estimated based on the data from Chongqing and Guangzhou Ionos- onde Stations. It is shown that the method is much improved for the predictions of one hour to four hours ahead. For the predictions of more than four hours ahead the prediction error reaches a saturation value, which is still lower than that of the “median” method. This new method could also be applied to the short-term forecasting of other ionospheric parame- ters. | LIU Ruiyuan LIU Shunlin XU Zhonghua WU Jian WANG Xianyi ZHANG Beichen HU Hongqiao | 2006 | Chinese Science Bulletin2006,51,3: | 17 |
| 4 | High-performance planar heterojunction perovskite solar cells: Preserving long charge carrier diffusion lengths and interracial engineering显示文摘 | Sai Bai Zhongwei Wu Xiaojing Wu Yizheng Jin Ni Zhao Zhihui Chen Qingqing Mei Xin Wang Zhizhen Ye Tao Song Ruiyuan Liu Shuit-tong Lee Baoquan Sun | 2014 | Nano Research2014,7,12: | 13 |
| 5 | Impact of impregnation pressure on desulfurization performance of Zn-based sorbents supported on semi-coke显示文摘High-pressure impregnation, a new preparation method for sorbents to remove H2S from hot coal gas, is introduced in this paper. Semi-coke (SC) and ZnO is selected as the support and active component of sorbent, respectively. The sorbent preparation process includes high-pressure impregnation, filtration, ovendry and calcination. The aim of this research is to primarily study the effects of the impregnation pressure on physical properties and desulfurization ability of the sorbent. The desulfurization experiment was carried out in a fixed-bed reactor at 500°C and a simulated coal gas used in this work was composed of CO (33 vol%), H2 (39 vol%), H2S (300 ppm in volume), and N2 (balance). Experimental results show that the pore structure of the SC support can be improved effectively and ZnO active component can be uniformly dispersed on the support, with the small particle size of 10-500 nm. Sorbents prepared using high-pressure impregnation have better desulfurization capacity and their active components have higher utilization rate. P20-ZnSC sorbent, obtained by high-pressure impregnation at 20 atm, has the best desulfurization ability with a sulfur capacity of 7.54 g S/100g sorbent and a breakthrough time of 44 h. Its desulfurization precision and efficiency of removing H2S from the middle temperature gases can reach <1 ppm and >99.7%, respectively, before sorbent breakthrough. | Xianrong Zheng Weiren Bao Qingmai Jin Ruiyuan He Liping Chang Kechang Xie | 2012 | Journal of Natural Gas Chemistry2012,21,1: | 10 |
| 6 | Integrated solar capacitors for energy conversion and storage显示文摘太阳能是最流行的干净精力来源之一并且是一种有希望的选择完成现代社会的增加的精力要求。太阳能电池长在为与高力量变换效率和低费用从日光收获精力的集中的研究注意下面。然而,光电的设备的力量产量由于太阳的放射的断断续续的本能受不了变化。作为自我驱动的系统集成太阳能电池和 energystorage 设备可以通过精力产量的电和操作的同时的存储解决这个问题。这评论与 supercapacitors 在新产生的太阳能电池的集成总结研究进步,与结构,材料,表演,和新设计特征上的强调。当前的挑战和未来前景与在这个领域里扩展研究和开发的目的被讨论。 | Ruiyuan Liu Yuqiang Liu Haiyang Zou Tao Song Baoquan Sun | 2017 | Nano Research2017,10,5: | 7 |
| 7 | Desulfurization kinetics of ZnO sorbent loaded on semi-coke support for hot coal gas显示文摘Zn-based sorbent (Z20SC) prepared through semi-coke support in 20 wt% zinc nitrate solution by high-pressure impregnation presents an excellent desulfurization capacity in hot coal gas,in which H2 S can not be nearly detected in the outlet gas before 20 h breakthrough time.The effects of the main operational conditions and the particle size of Z20SC sorbent on its desulfurization performances sorbent were investigated in a fixed-bed reactor and the desulfurization kinetics of Z20SC sorbent removing H2 S from hot coal gas was calculated based on experimental data.Results showed that the conversion of Z20SC sorbent desulfurization reaction increased with the decrease of the particle size of the sorbent and the increases of gas volumetric flow rate,reaction temperature and H 2 S content in inlet gas.Z20SC sorbent obtained from hydrothermal synthesis by high-pressure impregnation possessed much larger surface area and pore volume than semi-coke support,and they were significantly reduced after the desulfurization reaction.The equivalent grain model was reasonably used to analyze experimental data,in which k s=4.382×10-3 exp(-8.270×103/RgT) and Dep=1.262×10-4exp(1.522×104/RgT).It suggests that the desulfurization reaction of the Z20SC sorbent is mainly controlled by the chemical reaction in the initial stage and later by the diffusion through the reacted sorbent layer. | Zhiwei Ma Xianrong Zheng Liping Chang Ruiyuan He Weiren Bao | 2012 | Journal of Natural Gas Chemistry2012,21,5: | 7 |
| 8 | Tree-ring based PDSI reconstruction since 1853 AD in the source of the Fenhe River Basin,Shanxi Province,China显示文摘A robust tree-ring-width chronology was developed from two Pinus tabulaeformis sampling sites in the source of the Fenhe River,Shanxi Province,China.Based on the tree-ring-width indices,a 157-year long Palmer Drought Severity Index(PDSI) was reconstructed,which explains 53.7% of the variance of the modeled PDSI over the common period 1957-2008.The drought periods in the study area include 1914-1931 and 1970 to the present,whereas the wet periods were 1866-1892 and 1932-1969.The drought of 1914-1931 was a severe long-lasting drought with a low inter-annual variability,and the drought of 1970-2009 was an overall long-term drought with a high inter-annual variability.The period of 1866-1892 is a continuously wet period with a low inter-annual variability and the period of 1932-1969 is an overall long-term wet period with a high inter-annual variability.The reconstructed PDSI series in the source of the Fenhe River shows synchronous variations with the regional drought/wetness indices.Spatial correlation analyses indicate that the higher correlations lie exclusively in the Fenhe River Basin.This indicates that the reconstructed PDSI has regional representativeness and can represent the drought history of the entire Fenhe River Basin to some extent.Furthermore,the reconstructed PDSI matches with the variability of the per unit yield of summer grain crops in Shanxi Province very well and they have significant correlation.From a long-term perspective the reconstructed PDSI series could supply scientific and valuable information to the water resources management and then help the sustainable development in agricultural production,economic development,and ecosystem balance. | SUN JunYan LIU Yu SUN Bo WANG RuiYuan | 2012 | Science China Earth Sciences2012,55,11: | 6 |
| 9 | Variations of thioredoxin system contributes to increased susceptibility to apoptosis in cardiomyocytes of type 2 diabetic rats显示文摘心脏的复杂并发症是在糖尿病的死亡的领先的原因。thioredoxin (Trx ) 系统不管多么,并且是否被包含,在导致 myocardialinjury 和 apoptosis 的糖尿病的机制仍然保持不清楚。在这研究,男 SpragueDawleyrats 随机被划分成二个组:控制和糖尿病组,然后随机被划分成 fivedifferent timepoints (第一,第二,第 4,第 12,和第 24 星期) 。结果在类型显示出那导致糖尿病的心脏的损害 wasenhanced 2 只糖尿病老鼠由加重的心脏的机能障碍证实了生物化学的指示物,和 increasedmyocardial apoptosis (TUNEL 和 caspase-3 活动) 。在糖尿病的 ratswas 的心肌的 Trx 和 Trx reductase (TR ) 的活动显著地从第二个星期减少了并且不断地与疾病前进加重了。在糖尿病的老鼠, Trx1, Trx2, TR1,和 TR2 的 mRNA 表示首先被减少然后在第四个星期以后增加了。同时,这些 Trx 系统 memberswas 的蛋白质表示显著地在第 12 星期增加了。Trx 硝代被清除, Trx/ASK1 相互作用显著地被减少,并且 p38 的活动显著地在在第 12 星期的心脏的纸巾被提高。这些结果表明了那个 diabetesmay 原因心肌的损害和 apoptosis,和哪个伴有疾病的发展的程度。Themechanism 与糖尿病和 Trx 和 TR 的减少的活动的发展被联系。为 decreasedTrx 活动的原因可以包括:Trx 和 TR 蛋白质表示的减少;Trx 的硝代修正;并且 TXNIPexpression 的起来规定。 | Xiaoqin Zhao Yan Zhang Xiaoyu Li Ruiyuan Wang Xiangying Jiao | 2014 | Acta Biochimica et Biophysica Sinica2014,46,4: | 5 |
| 10 | Broadband transmission-type 1-bit coding metasurface for electromagnetic beam forming and scanning显示文摘Coding metasurfaces make it possible to manipulate electromagnetic(EM)waves digitally by means of several discrete particles.Hence,there have been rapid advances in this field recently.Here we propose a novel design of a broadband transmission-type coding metasurface,which is valid to both x-and y-polarized EM incidences from 8.1-12.5 GHz while satisfies the requirements of 1-bit coding without changing the polarization.Two types of multi-layer coding particles with different geometrical parameters are adopted to represent the digital states'0'and'1',which are easily promoted to terahertz and optics through modifying the size scale.To verify the ability to manipulate the EM waves,we first adopt the coding metasurface to achieve broadband beam forming by converting spherical waves to plane waves and realize high-directivity pencil beam in far field with low side lobes.We further arrange the particles according to the coding sequence 010101…to steer two symmetrical beams in different directions controlled by frequencies with the maximum range of the scanning angle of 30°-50.5°.The good agreements between the simulated and measured results validate the proposed broadband coding metasurface,indicating its huge potential in communication and radar imaging systems. | RuiYuan Wu Lei Bao LiangWei Wu TieJun Cui | 2020 | Science China(Physics,Mechanics & Astronomy)2020,63,8: | 5 |
| 11 | SuperDARN CUTLASS Finland radar observations of high-latitude magnetic reconnections under northward interplanetary magnetic field (IMF) conditions显示文摘A number of backscatter power enhancement events with 'equatorward-moving radar auroral forms' in the high-latitude ionosphere were observed by SuperDARN CUTLASS Finland radar when the IMF was northward during 09:00 -10:00 UT on 26 March 2004. These events were also associated with sunward flow enhancements at each location in the Northern Hemisphere which were shown in ionospheric convections measured by the SuperDARN radars. These are typical features of high-latitude (lobe) magnetic reconnections. The durations of the velocity enhancements imply that the evolution time of the lobe reconnections is about 8-16 min from their origin at the reconnection site to their addition to the magnetotail lobe again. In additional, the Double Star TC-1 spacecraft was moving from magnetosheath into magnetosphere, and crossing the magnetopause near the subsolar region during this interval, and observed typical low-latitude magnetic reconnection signatures. This infers that the dayside high- and low-latitude reconnections may occur simultaneously. | ZHANG QingHe LIU RuiYuan YANG HuiGen HU HongQiao ZHANG BeiChen DUNLOP Malcolm LESTER Mark BOGDANOVA Yulia WALSH Andrew | 2012 | Science China(Technological Sciences)2012,55,5: | 5 |
| 12 | The role of histone methylation in the development of digestive cancers:a potential direction for cancer management显示文摘Digestive cancers are the leading cause of cancer-related death worldwide and have high risks of morbidity and mortality.Histone methylation,which is mediated mainly by lysine methyltransferases,lysine demethylases,and protein arginine methyltransferases,has emerged as an essential mechanism regulating pathological processes in digestive cancers.Under certain conditions,aberrant expression of these modifiers leads to abnormal histone methylation or demethylation in the corresponding cancer-related genes,which contributes to different processes and phenotypes,such as carcinogenesis,proliferation,metabolic reprogramming,epithelial–mesenchymal transition,invasion,and migration,during digestive cancer development.In this review,we focus on the association between histone methylation regulation and the development of digestive cancers,including gastric cancer,liver cancer,pancreatic cancer,and colorectal cancer,as well as on its clinical application prospects,aiming to provide a new perspective on the management of digestive cancers. | Yuan Chen Bo Ren Jinshou Yang Huanyu Wang Gang Yang Ruiyuan Xu Lei You Yupei Zhao | 2020 | Signal Transduction and Targeted Therapy2020,5,1: | 4 |
| 13 | Mapping epistasis and environment × QTX interaction based on four-omics genotypes for the detected QTX loci controlling complex traits in tobacco显示文摘Using newly developed methods and software, association mapping was conducted for chromium content and total sugar in tobacco leaf, based on four-omics datasets. Our objective was to collect data on genotype and phenotype for 60 leaf samples at four developmental stages, from three plant architectural positions and for three cultivars that were grown in two locations. Association mapping was conducted to detect genetic variants at quantitative trait SNP(QTS) loci, quantitative trait transcript(QTT) differences,quantitative trait protein(QTP) variability, and quantitative trait metabolite(QTM) changes,which can be summarized as QTX locus variation. The total heritabilities of the four-omics loci for both traits tested were 23.60% for epistasis and 15.26% for treatment interaction.Epistasis and environment × treatment interaction had important impacts on complex traits at all-omics levels. For decreasing chromium content and increasing total sugar in tobacco leaf, six methylated loci can be directly used for marker-assisted selection, and expression of ten QTTs, seven QTPs and six QTMs can be modified by selection or cultivation. | Liyuan Zhou Ruiyuan Li Longjiang Fan Yuewei Shi Zhihong Wang Shengdong Xie Yijie Gui Xueliang Ren Jun Zhu | 2013 | The Crop Journal2013,1,2: | 4 |
| 14 | Perfection of Perovskite Grain Boundary Passivation by Rhodium Incorporation for Efficient and Stable Solar Cells显示文摘Organic cation and halide anion defects are omnipresent in the perovskite films,which will destroy perovskite electronic structure and downgrade the properties of devices.Defect passivation in halide perovskites is crucial to the application of solar cells.Herein,tiny amounts of trivalent rhodium ion incorporation can help the nucleation of perovskite grain and passivate the defects in the grain boundaries,which can improve efficiency and stability of perovskite solar cells.Through first-principle calculations,rhodium ion incorporation into the perovskite structure can induce ordered arrangement and tune bandgap.In experiment,rhodium ion incorporation with perovskite can contribute to preparing larger crystalline and uniform film,reducing trap-state density and enlarging charge carrier lifetime.After optimizing the content of 1% rhodium,the devices achieved an efficiency up to 20.71% without obvious hysteresis,from 19.09% of that pristine perovskite.In addition,the unencapsulated solar cells maintain 92% of its initial efficiency after 500 h in dry air.This work highlights the advantages of trivalent rhodium ion incorporation in the characteristics of perovskite solar cells,which will promote the future industrial application. | Wei Liu Nanjing Liu Shilei Ji Hongfeng Hua Yuhui Ma Ruiyuan Hu Jian Zhang Liang Chu Xing’ao Li Wei Huang | 2020 | Nano-Micro Letters2020,12,9: | 4 |
| 15 | Statistical characteristics of ionospheric backscatter observed by SuperDARN Zhongshan radar in Antarctica显示文摘Zhongshan HF radar, as one component of SuperDARN, has been established and in operation since April, 2010. Using data from the first two years of its operation, this paper investigates the radar's performance, the diurnal and seasonal variations of ionospheric echoes, and their dependence on geomagnetic activity. Statistical studies show that the occurrence of echoes in different beams varies at different frequencies, which arises from the direction of the beam and the area over which the beam can achieve the orthogonality condition between the wave vector and the Earth's magnetic field. The diurnal variation is obvious with double peak structures both in the occurrence rate and average power at 04-08 UT and 16-17 UT. The line-of-sight velocities are mainly positive on the dayside and negative on the nightside for Beam 0, which is the opposite of the trend for Beam 15. The spectral widths on the dayside are often higher than those on the nightside owing to the high energy particle precipitation in the cusp region. The seasonal variations are more obvious for those beams with larger numbers. The occurrence, the average power, the line-of-sight velocity, and the spectral widths are generally larger in the winter months than in the summer months. The influence of geomagnetic activity on radar echoes is significant. The peak echo occurrence appears on the dayside during geomagnetically quiet times, and shifts toward the nightside and exhibits an obvious decrease with increasing Kp. With increasing geomagnetic activity, the line-of-sight velocities increase, whereas the spectral widths decrease. The frequency dependence is investigated and it is found that in the operating frequency bands in 2010, 9-10 MHz is the most appropriate band for the SuperDARN Zhongshan radar. | HU Hongqiao LIU Erxiao LIU Ruiyuan YANG Huigen ZHANG Beichen | 2013 | Advances in Polar Science2013,24,1: | 4 |
| 16 | Astrocytes in depression and Alzheimer’s disease显示文摘Astrocytes are an abundant subgroup of cells in the central nervous system(CNS)that play a critical role in controlling neuronal circuits involved in emotion,learning,and memory.In clinical cases,multiple chronic brain diseases may cause psychosocial and cognitive impairment,such as depression and Alzheimer’s disease(AD).For years,complex pathological conditions driven by depression and AD have been widely perceived to contribute to a high risk of disability,resulting in gradual loss of self-care ability,lower life qualities,and vast burden on human society.Interestingly,correlational research on depression and AD has shown that depression might be a prodrome of progressive degenerative neurological disease.As a kind of multifunctional glial cell in the CNS,astrocytes maintain physiological function via supporting neuronal cells,modulating pathologic niche,and regulating energy metabolism.Mounting evidence has shown that astrocytic dysfunction is involved in the progression of depression and AD.We herein review the current findings on the roles and mechanisms of astrocytes in the development of depression and AD,with an implication of potential therapeutic avenue for these diseases by targeting astrocytes. | Yang Liao Qu Xing Qianqian Li Jing Zhang Ruiyuan Pan Zengqiang Yuan | 2021 | Frontiers of Medicine2021,15,6: | 4 |
| 17 | Progress in polar upper atmospheric physics research in China显示文摘The Chinese Antarctic Great Wall, Zhongshan, Kunlun and Arctic Yellow River stations have unique geographical locations, well suited to carry out polar upper atmospheric observations. This paper reviews the tremendous history of nearly 30 years of Chinese polar expeditions and major progress in polar upper atmospheric physics research. This includes the polar upper atmospheric physics conjugate observation system at Zhongshan Station in the Antarctic and Yellow River Station in the Arctic, and original research achievements in polar ionospheric fields, aurora and particle precipitation, the polar current system, polar plasma convection, geomagnetic pulsations and space plasma waves, inter-hemispheric comparisons of the space environment, space weather in polar regions, power spectrum of the incoherent scatter radar, ionospheric heating experiments and polar meso- spheric summer echoes, polar ionosphere-magnetosphere numerical simulation and others. Finally, prospects for Chinese polar upper atmospheric physics research are outlined. | LIU Ruiyuan YANG Huigen | 2012 | Advances in Polar Science2012,23,2: | 4 |
| 18 | Synthesis and characterization of oriented linked LiFePO4 nanoparticles with fast electron and ion transport for high-power lithium-ion batteries显示文摘有不同形态学和尺寸的 LiFePO 4 nanoparticles 作为表面活化剂用环境地良性、便宜的甘油经由一个 solvothermal 方法被综合。粒子的形态学,尺寸,和结构被发现仔细联系到甘油的集中。面向非主要连接了 LiFePO 4 nanorods --[010 ] 与甘油的合适的集中被获得。nanorods 显示出好电子、离子的传导性,导致优异的率能力和骑车的性能。这表演非主要被归因于面向的连接[010 ] ,小粒子尺寸沿着[010 ] ,并且在 Fe 地点的李的职业。162.4 | Yi Jiang Ruiyuan Tian Haiqiang Liu Jiankun Chen Xinghua Tan Lina Zhang Guangyao Liu Hanfu Wang Lianfeng Sun Weiguo Chu | 2015 | Nano Research2015,8,12: | 4 |
| 19 | Pathological features of COVID-19-associated lung injury:a preliminary proteomics report based on clinical samples显示文摘The COVID-19 pandemic has emerged as a global health emergency due to its association with severe pneumonia and relative high mortality.However,the molecular characteristics and pathological features underlying COVID-19 pneumonia remain largely unknown.To characterize molecular mechanisms underlying COVID-19 pathogenesis in the lung tissue using a proteomic approach,fresh lung tissues were obtained from newly deceased patients with COVID-19 pneumonia.After virus inactivation,a quantitative proteomic approach combined with bioinformatics analysis was used to detect proteomic changes in the SARS-CoV-2-infected lung tissues.We identified significant differentially expressed proteins involved in a variety of fundamental biological processes including cellular metabolism,blood coagulation,immune response,angiogenesis,and cell microenvironment regulation.Several inflammatory factors were upregulated,which was possibly caused by the activation of NF-κB signaling.Extensive dysregulation of the lung proteome in response to SARS-CoV-2 infection was discovered.Our results systematically outlined the molecular pathological features in terms of the lung response to SARS-CoV-2 infection,and provided the scientific basis for the therapeutic target that is urgently needed to control the COVID-19 pandemic. | Ling Leng Ruiyuan Cao Jie Ma Danlei Mou Yunping Zhu Wei Li Luye Lv Dunqin Gao Shikun Zhang Feng Gong Lei Zhao Bintao Qiu Haiping Xiang Zhongjie Hu Yingmei Feng Yan Dai Jiang Zhao Zhihong Wu Hongjun Li Wu Zhong | 2020 | Signal Transduction and Targeted Therapy2020,5,1: | 4 |
| 20 | Identification of Parameters in 2D-FEM of Valve Piping System within NPP Utilizing Seismic Response显示文摘Nuclear power plants(NPP)contain plenty of valve piping systems(VPS’s)which are categorized into high anti-seismic grades.Tasks such as seismic qualification,health monitoring and damage diagnosis of VPS’s in its design and operation processes all depend on finite element method.However,in engineering practice,there is always deviations between the theoretical and the measured responses due to the inaccurate value of the structural parameters in the model.The structure parameters identification of VPS within NPP is still an unexplored domain to a large extent.In this paper,the initial 2D-finite element model(FEM)for VPS with a DN80 gate valve was updated by utilizing seismic response.The objective function used in the model updating procedure is the vibration control equation error of the VPS.The experimental results show that the updated 2D-FEM can accurately predict the original dynamic characteristic of the VPS.It was also found the Rayleigh damping coefficients corresponding to the VPS vary slightly with the change in seismic excitation amplitude.The research displayed the complete procedure of updating the complex structured initial FEM by utilizing seismic response,and the results show that the parameters can be accurately identified even if the seismic response used for updating merely contained the fundamental frequency information of the structure. | Ruiyuan Xue Shurong Yu Xiheng Zhang | 2020 | Computers, Materials & Continua2020,,10: | 3 |